Heterocyclic compound and composition containing same

ABSTRACT

A heterocyclic compound is represented by formula (I):in which R2 represents a C1-C6 alkyl group optionally having one or more halogen atoms, n is 0, R3 represents a C1-C6 chain hydrocarbon group optionally having one or more substituents selected from Group B, q is 0, Het represents a group represented by the formulae Het 1 or Het 2, A1 represents a nitrogen atom, and Q2 represents an oxygen atom. The compound has excellent efficacy for controlling harmful arthropods. A composition is provided which contains the compound of formula (I) and one or more additional ingredients.

CROSS-REFERENCE TO RELATED APPLICATIONS

This application is a Section 371 of International Application No.PCT/JP2018/021157, filed Jun. 1, 2018, which was published in theJapanese language on Dec. 6, 2018 under International Publication No. WO2018/221720 A1, which claims priority under 35 U.S.C. § 119(b) toJapanese Application No. 2017-108998, filed on Jun. 1, 2017, JapaneseApplication No. 2017-245956, filed on Dec. 22, 2017, and JapaneseApplication No. 2018-070879, filed on Apr. 2, 2018, the disclosures ofwhich are incorporated herein by reference in their entireties.

TECHNICAL FIELD

The present invention is related to a certain class of heterocycliccompound, an intermediate compound thereof, and an agent for controllingharmful arthropods comprising the same.

BACKGROUND ART

To date, in order to control harmful arthropods, some compounds havebeen studied and come into practical use.

Also, a certain class of compound has been known to have an effect oncontrolling pests (see Patent Document 1).

CITATION LIST Patent Document

Patent Document 1: WO 2013/018928 pamphlet

SUMMARY OF THE INVENTION Problems to be Solved by Invention

An object of the present invention is to provide a compound having anexcellent efficacy for controlling harmful arthropods.

Means to Solve Problems

The present invention includes the followings.

[1] A compound represented by formula (I):

wherein,

R² represents a C1-C6 alkyl group optionally having one or more halogenatoms, a cyclopropyl group or a cyclopropylmethyl group,

n is 0, 1 or 2,

R³ represents a C1-C6 chain hydrocarbon group optionally having one ormore substituents selected from Group B, a C3-C7 cycloalkyl groupoptionally having one or more substituents selected from group E, aC3-C7 cycloalkenyl group optionally having one or more substituentsselected from Group J, a phenyl group optionally having one or moresubstituents selected from Group H, a five or six membered aromaticheterocyclic group optionally having one or more substituents selectedfrom Group H, OR¹², NR¹¹R¹², NR^(11a)R^(12a), NR²⁴NR¹¹R¹², NR²⁴OR¹¹,NR¹¹C(O)R¹³, NR²⁴NR¹¹C(O)R¹³, NR¹¹C(O)OR¹⁴, NR²⁴NR¹¹C(O)OR¹⁴,NR¹¹C(O)NR¹⁵R¹⁶, NR²⁴NR¹¹C(O) NR¹⁵R¹⁶, N═CHNR¹⁵R¹⁶, N═S(O)_(x)R¹⁵R¹⁶,C(O)R¹⁷, C(O)OR¹⁷, C(O)NR¹⁵R¹⁶, CR²⁴═NOR¹⁷, NR¹¹CR²⁴═NOR¹⁷, a cyanogroup, a nitro group, or a halogen atom,

q is 0, 1, 2 or 3, and when q is 2 or 3, a plurality of R³ may beidentical to or different from each other,

When two R³ are adjacent to each other, said two R³ may combinedtogether with a carbon atom to which they are attached to form benzenering, pyrrole ring, furan ring, thiophene ring, pyrazole ring, imidazolering, triazole ring, oxazole ring, isoxazole ring, thiazole ring,oxadiazole ring, thiadiazole ring, pyridine ring, pyridazine ring,pyrimidine ring, or pyrazine ring {the benzene ring, the pyrrole ring,the furan ring, the thiophene ring, the pyrazole ring, the imidazolering, the triazole ring, the oxazole ring, the isoxazole ring, thethiazole ring, the pyridine ring, the pyridazine ring, the pyrimidinering, and the pyrazine ring each independently may optionally have oneor more substituents selected from Group H},

Het represents a group represented by the following formula Het 1 or agroup represented by the following formula Het 2:

A¹ represents a nitrogen atom or CR⁶,

A² represents a nitrogen atom or CR^(4a),

A³ represents a nitrogen atom or CR^(4b),

A⁴ represents a nitrogen atom or CR^(4c),

Q¹ represents an oxygen atom or a sulfur atom,

Q² represents an oxygen atom, N—CN, N—NO₂, NR²⁰, N—C(O)R²⁰, orN—C(O)OR¹⁵, and when n is 2, two Q² may be identical to or differentfrom each other,

R²⁰ represents a C1-C6 alkyl group optionally having one or more halogenatoms, or a hydrogen atom,

R⁵ represents a C1-C6 chain hydrocarbon group optionally having one ormore substituents selected from group F, a C3-C6 cycloalkyl groupoptionally having one or more substituents selected from Group J, aphenyl group optionally having one or more substituents selected fromGroup H, or a five or six membered aromatic heterocyclic groupoptionally having one or more substituents selected from Group H,

R^(4a), R^(4b) and R^(4c) are identical to or different from each otherand each represents independently a C1-C6 chain hydrocarbon groupoptionally having one or more halogen atoms, a nitro group, OR¹⁸,NR¹⁸R¹⁹, a cyano group, an amino group, a halogen atom, or a hydrogenatom,

R⁶ represents a hydrogen atom or a halogen atom,

T represents a C1-C10 chain hydrocarbon group, a (C1-C5 alkoxy)C2-C5alkyl group, a (C1-C5 alkylsulfanyl)C2-C5 alkyl group, a (C1-C5alkylsulfinyl)C2-C5 alkyl group, a (C1-C5 alkylsulfonyl)C2-C5 alkylgroup {the C1-C10 chain hydrocarbon group, the (C1-C5 alkoxy)C2-C5 alkylgroup, the (C1-C5 alkylsulfanyl)C2-C5 alkyl group, the (C1-C5alkylsulfinyl)C2-C5 alkyl group, and the (C1-C5 alkylsulfonyl)C2-C5alkyl group each independently have one or more substituents selectedfrom the group consisting of a cyano group and a halogen atom}, a (C3-C7cycloalkyl)C1-C3 alkyl group, a C3-C7 cycloalkyl group {the (C3-C7cycloalkyl)C1-C3 alkyl group and the C3-C7 cycloalkyl group eachindependently have one or more substituents selected from the groupconsisting of a cyano group, a halogen atom and a C1-C6 haloalkylgroup}, OR¹, S(O)_(v)R¹, OS(O)₂R¹, CH₂OR¹, NR¹R²⁹, C(O)R¹, C(O)NR¹R²⁹,NR²⁹C(O)R¹, N═CR¹R³⁰, a group represented by formula T-1, a grouprepresented by formula T-2, a group represented by formula T-3, a grouprepresented by formula T-4, a group represented by formula T-5, a grouprepresented by formula T-6, a group represented by formula T-7, a grouprepresented by formula T-8, a group represented by formula T-9, a grouprepresented by formula T-10, a group represented by formula T-11, or agroup represented by formula T-12:

X¹ represents a nitrogen atom or CR^(1a),

X² represents a nitrogen atom or CR^(1b),

X³ represents a nitrogen atom or CR^(1c),

X⁴ represents a nitrogen atom or CR^(1d),

X⁵ represents a nitrogen atom or CR^(1e),

R^(1x) represents a C1-C5 chain hydrocarbon group having one or morehalogen atoms, OR⁷, OS(O)₂R⁷, S(O)_(m)R⁷, NR⁸S(O)₂R⁷, or a halogen atom,

R^(1a), R^(1b), R^(1c), R^(1d), and R^(1e) are identical to or differentfrom each other and each represents independently a C1-C6 chainhydrocarbon group optionally having one or more halogen atoms, a C3-C6cycloalkyl group optionally having one or more halogen atoms, a halogenatom, or a hydrogen atom,

Y² represents NR²⁵, an oxygen atom or a sulfur atom,

Y² represents a nitrogen atom or CR²⁶,

Y³ represents a nitrogen atom or CR²⁷,

Y⁴ represents a nitrogen atom or CR²⁸,

R²⁵, R²⁶, R²⁷ and R²⁸ are identical to or different from each other andeach represents independently a C1-C6 chain hydrocarbon group optionallyhaving one or more halogen atoms, a C3-C6 cycloalkyl group optionallyhaving one or more halogen atoms, a halogen atom or a hydrogen atom,

R^(1y) represents a C1-C5 chain hydrocarbon group having one or morehalogen atoms, OR⁷, OS(O)₂R⁷, S(O)_(m)R⁷, NR⁸S(O)₂R⁷, a cyano group, ora halogen atom,

R^(1ay) and R⁷ are identical to or different from each other and eachrepresents independently a C1-C6 chain hydrocarbon group having one ormore halogen atoms,

m and v are identical to or different from each other and each is 0, 1or 2,

R¹ represents a C1-C10 chain hydrocarbon group, a (C1-C5 alkoxy)C2-C5alkyl group, a (C1-C5 alkylsulfanyl)C2-C5 alkyl group, a (C1-C5alkylsulfinyl)C2-C5 alkyl group, a (C1-C5 alkylsulfonyl)C2-C5 alkylgroup {the C1-C10 chain hydrocarbon group, the (C1-C5 alkoxy)C2-C5 alkylgroup, the (C1-C5 alkylsulfanyl)C2-C5 alkyl group, the (C1-C5alkylsulfinyl)C2-C5 alkyl group, and the (C1-C5 alkylsulfonyl)C2-C5alkyl group each independently have one or more substituents selectedfrom the group consisting of a cyano group and a halogen atom}, a (C3-C7cycloalkyl)C1-C3 alkyl group, or a C3-C7 cycloalkyl group {the (C3-C7cycloalkyl)C1-C3 alkyl group and the C3-C7 cycloalkyl group eachindependently have one or more substituents selected from the groupconsisting of a cyano group, a halogen atom and a C1-C6 haloalkylgroup},

R³⁰ represents a C1-C6 chain hydrocarbon group optionally having one ormore halogen atoms, a halogen atom, OR³⁵, NR³⁶R³⁷, or a hydrogen atom,

R¹⁸ and R³⁵ are identical to or different from each other and eachrepresents independently a C1-C6 chain hydrocarbon group optionallyhaving one or more halogen atoms,

R¹⁷ represents a C1-C6 chain hydrocarbon group optionally having one ormore halogen atoms, a phenyl group optionally having one or moresubstituents selected from Group D, or a hydrogen atom,

R⁸, R¹¹, R¹⁹, R²⁴, R²⁹, R³⁶, and R³⁷ are identical to or different fromeach other and each represents independently a C1-C6 chain hydrocarbongroup optionally having one or more halogen atoms, or a hydrogen atom,

R¹² represents a C1-C6 chain hydrocarbon group optionally having one ormore substituents selected from Group F, a C3-C7 cycloalkyl groupoptionally having one or more substituents selected from. Group J, aC3-C7 cycloalkenyl group optionally having one or more substituentsselected from Group J, a phenyl group, a six membered heterocyclic group{the phenyl group, and the six membered heterocyclic group eachindependently may optionally have one or more substituents selected fromGroup D}, a hydrogen atom, or a S(O)₂R²³,

R²³ represents a C1-C6 chain hydrocarbon group optionally having one ormore halogen atoms, or a phenyl group optionally having one or moresubstituents selected from Group D,

R^(11a) and R^(12a) combine together with the nitrogen atom to whichthey are attached to form a three to seven membered nonaromaticheterocyclic group optionally having one or more substituents selectedfrom group E,

R¹³ represents a hydrogen atom, a C1-C6 chain hydrocarbon groupoptionally having one or more halogen atoms, a C3-C7 cycloalkyl groupoptionally having one or more halogen atoms, a (C3-C6 cycloalkyl)C1-C3alkyl group optionally having one or more halogen atoms, a phenyl groupoptionally having one or more substituents selected from Group D, or afive or six membered aromatic heterocyclic group optionally having oneor more substituents selected from Group D,

R¹⁴ represents a C1-C6 chain hydrocarbon group optionally having one ormore halogen atoms, a C3-C7 cycloalkyl group optionally having one ormore halogen atoms, a (C3-C6 cycloalkyl)C1-C3 alkyl group optionallyhaving one or more halogen atoms, or a phenyl C1-C3 alkyl group {thephenyl moiety in the phenyl C1-C3 alkyl group may optionally have one ormore substituents selected from Group D},

R¹⁵ represents a C1-C6 alkyl group optionally having one or more halogenatoms, or a hydrogen atom,

R¹⁶ represents a C1-C6 chain hydrocarbon group optionally having one ormore substituents selected from Group F, a C3-C7 cycloalkyl groupoptionally having one or more substituents selected from Group J,S(O)₂R²³ or a hydrogen atom,

x is 0 or 1,

Group B: a group consisting of a C1-C6 alkoxy group optionally havingone or more halogen atoms, a C3-C6 alkenyloxy group optionally havingone or more halogen atoms, a C3-C6 alkynyloxy group optionally havingone or more halogen atoms, a C1-C6 alkylsulfanyl group optionally havingone or more halogen atoms, a C1-C6 alkylsulfinyl group optionally havingone or more halogen atoms, a C1-C6 alkylsulfonyl group optionally havingone or more halogen atoms, a C3-C6 cycloalkyl group optionally havingone or more halogen atoms, a cyano group, a hydroxy group, and a halogenatom,

Group D: a group consisting of a C1-C6 chain hydrocarbon groupoptionally having one or more halogen atoms, a hydroxy group, a C1-C6alkoxy group optionally having one or more halogen atoms, a C3-C6alkenyloxy group optionally having one or more halogen atoms, a C3-C6alkynyloxy group optionally having one or more halogen atoms, a sulfanylgroup, a C1-C6 alkylsulfanyl group optionally having one or more halogenatoms, a C1-C6 alkylsulfinyl group optionally having one or more halogenatoms, a C1-C6 alkylsulfonyl group optionally having one or more halogenatoms, an amino group, NR⁹R¹⁰, C(O)R¹⁰, OC(O)R⁹, C(O)OR⁹, a cyano group,a nitro group, and a halogen atom,

R⁹ represents a C1-C6 alkyl group optionally having one or more halogenatoms, or a C3-C6 cycloalkyl group optionally having one or more halogenatoms,

R¹⁰ represents a C1-C6 alkyl group optionally having one or more halogenatoms, a C3-C6 cycloalkyl group optionally having one or more halogenatoms, or a hydrogen atom,

Group E; a group consisting of a C1-C6 chain hydrocarbon groupoptionally having one or more halogen atoms, a C1-C6 alkoxy groupoptionally having one or more halogen atoms, a C3-C6 alkenyloxy groupoptionally having one or more halogen atoms, a C3-C6 alkynyloxy groupoptionally having one or more halogen atoms, a halogen atom, an oxogroup, a hydroxy group, a cyano group, and a nitro group;

Group F: a group consisting of a C3-C6 cycloalkyl group optionallyhaving one or more halogen atoms, a phenyl group or a six memberedaromatic heterocyclic group {the phenyl group and the six memberedaromatic heterocyclic group each independently may optionally have oneor more substituents selected from Group D}, OR¹⁰, an amino group,NR⁹R¹⁰, a halogen atom, a nitro group, and a cyano group;

Group H: a group consisting of a five or six membered aromaticheterocyclic group, a C1-C6 alkyl group optionally having one or morehalogen atoms, a C3-C6 cycloalkyl group optionally having one or morehalogen atoms, OR¹⁰, an amino group, NR⁹R¹⁰, C(O)R¹⁰, C(O)NR⁹R¹⁰,OC(O)R⁹, OC(O)OR⁹, NR¹⁰C(O)R⁹, NR¹⁰C(O)OR⁹, C(O)OR¹⁰, a halogen atom, anitro group, and a cyano group;

Group J; a group consisting of a C1-C6 alkyl group optionally having oneor more halogen atoms, a halogen atom, a cyano group, a triazolyl group,and NR¹⁰C(O)R⁹. (hereinafter, referred to as “Present compound Z” or“Compound Z of the present invention”).

[2] The compound according to [1] wherein

T represents a C1-C10 chain hydrocarbon group having one or more halogenatoms, a (C1-C5 alkoxy)C2-C5 alkyl group having one or more halogenatoms, a (C1-C5 alkylsulfanyl)C2-C5 alkyl group having one or morehalogen atoms, a (C1-C5 alkylsulfinyl)C2-C5 alkyl group having one ormore halogen atoms, a (C1-C5 alkylsulfonyl)C2-C5 alkyl group having oneor more halogen atoms, a (C3-C7 cycloalkyl)C1-C3 alkyl group having oneor more substituents selected from Group G, a C3-C7 cycloalkyl grouphaving one or more substituents selected from Group G, OR¹, S(O)_(v)R¹,OS(O)₂R¹, CH₂OR¹, NR¹R²⁹, C(O)R¹, C(O)NR¹R²⁹, NR²⁹C(O)R¹, N═CR¹R³⁰, agroup represented by formula T-1, a group represented by formula T-2, agroup represented by formula T-3, a group represented by formula T-4, agroup represented by formula T-5, a group represented by formula T-6, agroup represented by formula T-7, a group represented by formula T-8, agroup represented by formula T-9, a group represented by formula T-10, agroup represented by formula T-11, or a group represented by formulaT-12, and

R¹ represents a C1-C10 chain hydrocarbon group having one or morehalogen atoms, a (C1-C5 alkoxy)C2-C5 alkyl group having one or morehalogen atoms, a (C1-C5 alkylsulfanyl)C2-C5 alkyl group having one ormore halogen atoms, a (C1-C5 alkylsulfinyl)C2-C5 alkyl group having oneor more halogen atoms, a (C1-C5 alkylsulfonyl)C2-C5 alkyl group havingone or more halogen atoms, a (C3-C7 cycloalkyl)C1-C3 alkyl group havingone or more substituents selected from Group G, or a C3-C7 cycloalkylgroup having one or more substituents selected from Group G.

(hereinafter, referred to as “Present compound” or “Compound of thepresent invention”).

[3] The compound according to [1] or [2] wherein A¹ represents CH.

[4] The compound according to [1] or [2] wherein A¹ represents anitrogen atom.

[5] The compound according to any one of [1] to [4] wherein Hetrepresents Het 1.

[6] The compound according to any one of [1] to [4] wherein Hetrepresents Het 2.

[7] The compound according to any one of [1] to [4] wherein Hetrepresents Het 1, A² represents CR^(4a), and A³ represents CR^(4b).

[8] The compound according to any one of [1] to [4] wherein Hetrepresents Het 2, A² represents CR^(4a), and A⁴ represents CR^(4c).

[9] The compound according to any one of [1] to [8] wherein Q¹represents an oxygen atom, T represents a C1-C10 chain hydrocarbon grouphaving one or more halogen atoms, OR¹, S(O)_(v)R¹, OS(O)₂R¹, NR¹R²⁹, agroup represented by formula T-1, a group represented by formula T-2, agroup represented by formula T-3, a group represented by formula T-4, ora group represented by formula T-8.[10] The compound according to any one of [1] to [8] wherein Q¹represents an oxygen atom, T represents a C1-C5 chain hydrocarbon grouphaving one or more halogen atoms, OR¹, S(O)_(v)R¹, OS(O)₂R¹, NR¹R²⁹, agroup represented by formula T-1, a group represented by formula T-2, agroup represented by formula T-3, a group represented by formula T-4, ora group represented by formula T-8, R¹, R^(1x) and R^(1y) are identicalto or different from each other and each represents independently aC1-C5 chain hydrocarbon group having one or more halogen atoms, and q is0 or 1.[11] The compound according to any one of [1] to [8] wherein Q¹represents an oxygen atom, T represents a C1-C5 chain hydrocarbon grouphaving one or more halogen atoms, or OR¹, R¹ represents a C1-C5 chainhydrocarbon group having one or more halogen atoms, and q is 0 or 1.[12] The compound according to any one of [1] to [11] wherein R³represents a C1-C6 alkyl group optionally having one or moresubstituents selected from Group B, a C3-C7 cycloalkyl group optionallyhaving one or more substituents selected from Group E, a phenyl group, afive aromatic heterocyclic group containing one to four nitrogen atoms,a six aromatic heterocyclic group {the phenyl group, the five aromaticheterocyclic group containing one to four nitrogen atoms, and the sixaromatic heterocyclic group each independently may optionally have oneor more substituents selected from Group J}, NR¹¹R¹², NR¹¹C(O)OR¹⁴,OR¹², or a halogen atom.[13] The compound according to any one of [1] to [12] wherein R²represents an ethyl group.[14] The compound according to any one of [1] to [13] wherein Q²represents an oxygen atom.[15] A composition for controlling harmful arthropod comprising thecompound according to any one of [1] to [14] and an inert carrier.[16] A method for controlling harmful arthropod which comprises applyingan effective amount of the compound according to any one of [1] to [14]to a harmful arthropod or a habitat where a harmful arthropod lives.[17] A method for controlling harmful arthropod which comprises applyingan effective amount of the compound according to any one of [1] to [14]to a plant or a soil where a plant grows.[18] A method for controlling harmful arthropod which comprises applyingan effective amount of the compound according to any one of [1] to [14]to a seed or a bulb.[19] A composition comprising one or more ingredients selected from thegroup consisting of the following Group (a), Group (b), Group (c), Group(d) and Group (e), and the compound according to any one of [1] to [14](hereinafter, referred to as “Present composition” or “Composition ofthe present invention”),

Group (a): one or more ingredients selected from the group consisting ofinsecticidal ingredients, miticidal ingredients, and nematicidalingredients;

Group (b): fungicidal ingredients;

Group (c): plant growth modulating ingredients;

Group (d): phytotoxicity-reducing ingredients; and

Group (e): synergist ingredients.

[20] A composition for controlling pest comprising the compositionaccording to [19] and an inert carrier.

[21] A method for controlling pest which comprises applying an effectiveamount of the composition according to [19] to a pest or a habitat wherea pest lives.

[22] A method for controlling pest which comprises applying an effectiveamount of the composition according to [19] to a plant or a soil where aplant grows. [23] A method for controlling pest which comprises applyingan effective amount of the compound according to [19] to a seed or abulb.[24] A seed or bulb carrying an effective amount of the compoundaccording to any one of [1] to [14] or an effective amount of thecomposition according to [19].[25] A compound represented by formula (II):

[wherein,

R² represents a C1-C6 alkyl group optionally having one or more halogenatoms, a cyclopropyl group or a cyclopropylmethyl group,

n is 0, 1 or 2,

A² represents a nitrogen atom or CR^(4a),

a combination of A³ and A⁴ represents a combination where A³ representsa nitrogen atom, A⁴ represents a nitrogen atom or CR^(4c), or acombination where A³ represents CR^(4b), and A⁴ represents a nitrogenatom,

R^(4a), R^(4b) and R^(4c) are identical to or different from each otherand each represents independently a C1-C6 chain hydrocarbon groupoptionally having one or more halogen atoms, a nitro group, OR¹⁸,NR¹⁸R¹⁹, a cyano group, an amino group, a halogen atom, or a hydrogenatom,

R¹⁹ represents a C1-C6 chain hydrocarbon group optionally having one ormore halogen atoms, or a hydrogen atom,

R^(w) represents a C1-C6 chain hydrocarbon group optionally having oneor more halogen atoms, a benzyl group optionally having one or moresubstituents selected from Group A, a C2-C7 alkylcarbonyl group, a(C1-C3 alkoxy)methyl group, or a hydrogen atom,

T^(w) represents a C1-C10 chain hydrocarbon group, a (C1-C5 alkoxy)C2-C5alkyl group, a (C1-C5 alkylsulfanyl)C2-C5 alkyl group, a (C1-C5alkylsulfinyl)C2-C5 alkyl group, a (C1-C5 alkylsulfonyl)C2-C5 alkylgroup {the C1-C10 chain hydrocarbon group, the (C1-C5 alkoxy)C2-C5 alkylgroup, the (C1-C5 alkylsulfanyl)C2-C5 alkyl group, the (C1-C5alkylsulfinyl)C2-C5 alkyl group, and the (C1-C5 alkylsulfonyl)C2-C5alkyl group each independently have one or more substituents selectedfrom the group consisting of a cyano group and a halogen atom}, a (C3-C7cycloalkyl)C1-C3 alkyl group or a C3-C7 cycloalkyl group {the (C3-C7cycloalkyl)C1-C3 alkyl group and the C3-C7 cycloalkyl group eachindependently have one or more substituents selected from the groupconsisting of a cyano group, a halogen atom and a C1-C6 haloalkylgroup}, OR¹, S(O)_(v)R¹, OS(O)₂R¹, CH2OR¹, NR¹R²⁹, C(O)R¹, C(O)NR¹R²⁹,NR²⁹C(O)R¹, N═CR¹R³⁰, a group represented by formula T-1, a grouprepresented by formula T-2, a group represented by formula T-3, a grouprepresented by formula T-4, a group represented by formula T-5, a grouprepresented by formula T-6, a group represented by formula T-7, a grouprepresented by formula T-8, a group represented by formula T-9, a grouprepresented by formula T-10, a group represented by formula T-11, or agroup represented by formula T-12, a halogen atom, a C1-C6 alkylsulfanylgroup, a C1-C6 alkylsulfinyl group, a C1-C6 alkylsulfonyl group {theC1-C6 alkylsulfanyl group, the C1-C6 alkylsulfinyl group, and the C1-C6alkylsulfonyl group each may optionally have a C3-C6 cycloalkyl group},a C3-C6 cycloalkylsulfanyl group, a C3-C6 cycloalkylsulfinyl group, aC3-C6 cycloalkylsulfonyl group, a benzyloxy group optionally having oneor more substituents selected from Group A, a C2-C7 alkylcarbonyloxygroup optionally having one or more halogen atoms, a (C1-C3alkoxy)methoxy group, or a hydroxy group,

X¹ represents a nitrogen atom or CR^(1a),

X² represents a nitrogen atom or CR^(1b),

X³ represents a nitrogen atom or CR^(1c),

X⁴ represents a nitrogen atom or CR^(1d),

X⁵ represents a nitrogen atom or CR^(1e),

R^(1x) represents a C1-C5 chain hydrocarbon group having one or morehalogen atoms, OR⁷, OS(O)₂R⁷, S(O)_(m)R⁷, NR⁸S(O)₂R⁷, or a halogen atom,

R^(1a), R^(1b), R^(1c), R^(1d), and R^(1e) are identical to or differentfrom each other and each represents independently a C1-C6 chainhydrocarbon group optionally having one or more halogen atoms, a C3-C6cycloalkyl group optionally having one or more halogen atoms, a halogenatom, or a hydrogen atom,

Y¹ represents NR²⁵, an oxygen atom or a sulfur atom,

Y² represents a nitrogen atom or CR²⁶,

Y³ represents a nitrogen atom or CR²⁷,

Y⁴ represents a nitrogen atom or CR²⁸,

R²⁵, R²⁶, R²⁷ and R²⁹ are identical to or different from each other andeach represents independently a C1-C6 chain hydrocarbon group optionallyhaving one or more halogen atoms, a C3-C6 cycloalkyl group optionallyhaving one or more halogen atoms, a halogen atom or a hydrogen atom,

R^(1y) represents a C1-C5 chain hydrocarbon group having one or morehalogen atoms, OR⁷, OS(O)₂R⁷, S(O)_(m)R⁷, NR⁸S(O)₂R⁷, a cyano group, ora halogen atoms,

R^(1ay) and R⁷ are identical to or different from each other and eachrepresents independently a C1-C6 chain hydrocarbon group having one ormore halogen atoms,

m and v are identical to or different from each other and each is 0, 1or 2,

R¹ represents a C1-C10 chain hydrocarbon group, a (C1-C5 alkoxy)C2-C5alkyl group, a (C1-C5 alkylsulfanyl)C2-C5 alkyl group, a (C1-C5alkylsulfinyl)C2-C5 alkyl group, a (C1-C5 alkylsulfonyl)C2-C5 alkylgroup {the C1-C10 chain hydrocarbon group, the (C1-C5 alkoxy)C2-C5 alkylgroup, the (C1-C5 alkylsulfanyl)C2-C5 alkyl group, the (C1-C5alkylsulfinyl)C2-C5 alkyl group, and the (C1-C5 alkylsulfonyl)C2-C5alkyl group each independently have one or more substituents selectedfrom the group consisting of a cyano group and a halogen atom}, a (C3-C7cycloalkyl)C1-C3 alkyl group, or a C3-C7 cycloalkyl group {the (C3-C7cycloalkyl)C1-C3 alkyl group and the C3-C7 cycloalkyl group eachindependently have one or more substituents selected from the groupconsisting of a cyano group, a halogen atom and a C1-C6 haloalkylgroup},

R³⁰ represents a C1-C6 chain hydrocarbon group optionally having one ormore halogen atoms, a halogen atom, OR³⁵, NR³⁵R³⁷, or a hydrogen atom,

R¹⁸ and R³⁵ are identical to or different from each other and eachrepresents independently a C1-C6 chain hydrocarbon group optionallyhaving one or more halogen atoms,

R⁸, R²⁹, R³⁶, and R³⁷ are identical to or different from each other andeach represents independently a C1-C6 chain hydrocarbon group optionallyhaving one or more halogen atoms, or a hydrogen atom,

Group A: a group consisting of a C1-C6 alkyl group optionally having oneor more halogen atoms, a C1-C6 alkoxy group optionally having one ormore halogen atoms, a halogen atom, a cyano group and a nitro group.]

(hereinafter, referred to as “Intermediate compound D”).

[26] A compound represented by formula (III):

[wherein,

R² represents a C1-C6 alkyl group optionally having one or more halogenatoms, a cyclopropyl group or a cyclopropylmethyl group,

n is 0, 1 or 2,

A¹ represents a nitrogen atom or CR⁶,

A² represents a nitrogen atom or CR^(4a),

a combination of A³ and A⁴ represents a combination where A³ representsa nitrogen atom, A⁴ represents a nitrogen atom or CR^(4c), or acombination where A³ represents CR^(4b), and A⁴ represents a nitrogenatom,

R^(4a), R^(4b) and R^(4c) are identical to or different from each otherand each represents independently a C1-C6, chain hydrocarbon groupoptionally having one or more halogen atoms, a nitro group, OR¹⁸,NR¹⁸R¹⁹, a cyano group, an amino group, a halogen atom, or a hydrogenatom,

R⁶ represents a hydrogen atom or a halogen atom,

R^(w) represents a C1-C6 chain hydrocarbon group optionally having oneor more halogen atoms, a benzyl group optionally having one or moresubstituents selected from Group A, a C2-C7 alkylcarbonyl group, a(C1-C3 alkoxy)methyl group, or a hydrogen atom,

T^(W2) represents a C1-C10 chain hydrocarbon group, a (C1-C5alkoxy)C2-C5 alkyl group, a (C1-C5 alkylsulfanyl)C2-C5 alkyl group, a(C1-C5 alkylsulfinyl)C2-C5 alkyl group, a (C1-C5 alkylsulfonyl)C2-C5alkyl group {the C1-C10 chain hydrocarbon group, the (C1-C5 alkoxy)C2-C5alkyl group, the (C1-C5 alkylsulfanyl)C2-C5 alkyl group, the (C1-C5alkylsulfinyl)C2-C5 alkyl group, and the (C1-C5 alkylsulfonyl)C2-C5alkyl group each independently have one or more substituents selectedfrom the group consisting of a cyano group and a halogen atom}, a (C3-C7cycloalkyl)C1-C3 alkyl group or a C3-C7 cycloalkyl group {the (C3-C7cycloalkyl)C1-C3 alkyl group and the C3-C7 cycloalkyl group eachindependently have one or more substituents selected from the groupconsisting of a cyano group, a halogen atom and a C1-C6 haloalkylgroup}, OR¹, S(O)_(v)R¹, OS(O)₂R¹, CH₂OR¹, NR¹R²⁹, C(O)R¹, C(O)NR¹R²⁹,NR²⁹C(O)R¹, N═CR¹R³⁰, a group represented by formula T-1, a grouprepresented by formula T-2, a group represented by formula T-3, a grouprepresented by formula T-4, a group represented by formula T-5, a grouprepresented by formula T-6, a group represented by formula T-7, a grouprepresented by formula T-8, a group represented by formula T-9, a grouprepresented by formula T-10, a group represented by formula T-11, or agroup represented by formula T-12, a halogen atom, a C1-C6 alkoxy group,a C1-C6 alkylsulfanyl group, a C1-C6 alkylsulfinyl group, a C1-C6alkylsulfonyl group {the C1-C6 alkylsulfanyl group, the C1-C6alkylsulfinyl group, and the C1-C6 alkylsulfonyl group eachindependently may optionally have a C3-C6 cycloalkyl group}, a C3-C6cycloalkylsulfanyl group, a C3-C6 cycloalkylsulfinyl group, a C3-C6cycloalkylsulfonyl group, a benzyloxy group optionally having one ormore substituents selected from Group A, a C2-C7 alkylcarbonyloxy groupoptionally having one or more halogen atoms, a (C1-C3 alkoxy)methoxygroup, or a hydroxy group,

X¹ represents a nitrogen atom or CR^(1a),

X² represents a nitrogen atom or CR^(1b),

X³ represents a nitrogen atom or CR^(1c),

X⁴ represents a nitrogen atom or CR^(1d),

X⁵ represents a nitrogen atom or CR^(3e),

R^(1x) represents a C1-C5 chain hydrocarbon group having one or morehalogen atoms, OR⁷, OS(O)₂R⁷, S(O)_(m)R⁷, NR⁸S(O)₂R⁷, or a halogen atom,

R^(1a), R^(1b), R^(1c), R^(1d), and R^(1e) are identical to or differentfrom each other and each represents independently a C1-C6 chainhydrocarbon group optionally having one or more halogen atoms, a C3-C6cycloalkyl group optionally having one or more halogen atoms, a halogenatom, or a hydrogen atom,

Y¹ represents NR²⁵, an oxygen atom or a sulfur atom,

Y² represents a nitrogen atom or CR²⁶,

Y³ represents a nitrogen atom or CR²⁷,

Y⁴ represents a nitrogen atom or CR²⁸,

R²⁵, R²⁶, R²⁷ and R²⁸ are identical to or different from each other andeach represents independently a C1-C6 chain hydrocarbon group optionallyhaving one or more halogen atoms, a C3-C6 cycloalkyl group optionallyhaving one or more halogen atoms, a halogen atom or a hydrogen atom,

R^(1y) represents a C1-C5 chain hydrocarbon group having one or morehalogen atoms, OR⁷, OS(O)₂R⁷, S(O)_(m)R⁷, NR⁸S(O)₂R⁷, a cyano group, ora halogen atom,

R^(1ay) and R⁷ are identical to or different from each other and eachrepresents independently a C1-C6 chain hydrocarbon group having one ormore halogen atoms,

m and v are identical to or different from each other and each is 0, 1or 2,

R¹ represents a C1-C10 chain hydrocarbon group, a (C1-C5 alkoxy)C2-C5alkyl group, a (C1-C5 alkylsulfanyl)C2-C5 alkyl group, a (C1-C5alkylsulfinyl)C2-C5 alkyl group, a (C1-C5 alkylsulfonyl)C2-C5 alkylgroup {the C1-C10 chain hydrocarbon group, the (C1-C5 alkoxy)C2-C5 alkylgroup, the (C1-C5 alkylsulfanyl)C2-C5 alkyl group, the (C1-C5alkylsulfinyl)C2-C5 alkyl group, and the (C1-C5 alkylsulfonyl)C2-C5alkyl group each independently have one or more substituents selectedfrom the group consisting of a cyano group and a halogen atom}, a (C3-C7cycloalkyl)C1-C3 alkyl group, or a C3-C7 cycloalkyl group {the (C3-C7cycloalkyl)C1-C3 alkyl group and the C3-C7 cycloalkyl group eachindependently have one or more substituents selected from the groupconsisting of a cyano group, a halogen atom and a C1-C6 haloalkylgroup},

R³⁰ represents a C1-C6 chain hydrocarbon group optionally having one ormore halogen atoms, a halogen atom, OR³⁵, NR³⁶R³⁷, or a hydrogen atom,

R¹⁸ and R³⁵ are identical to or different from each other and eachrepresents independently a C1-C6 chain hydrocarbon group optionallyhaving one or more halogen atoms,

R³ represents a C1-C6 chain hydrocarbon group optionally having one ormore substituents selected from Group B, a C3-C7 cycloalkyl groupoptionally having one or more substituents selected from group E, aC3-C7 cycloalkenyl group optionally having one or more substituentsselected from Group J, a phenyl group optionally having one or moresubstituents selected from Group H, a five or six membered aromaticheterocyclic group optionally having one or more substituents selectedfrom Group H, OR¹², NR¹¹R¹², NR^(11a)R^(12a), NR²⁴NR¹¹R¹², NR²⁴OR¹¹,NR¹¹C(O)R¹³, NR²⁴NR¹¹C(O)R¹³, NR¹¹C(O)OR¹⁴, NR²⁴NR¹¹C(O)OR¹⁴,NR¹¹C(O)NR¹⁵R¹⁶, NR²⁴NR¹¹C(O)NR¹⁵R¹⁶, N═CHNR¹⁵R¹⁶, N═S(O)_(x)R¹⁵R¹⁶,C(O)R¹⁷, C(O)OR¹⁷, C(O)NR¹⁵R¹⁶, CR²⁴═NOR¹⁷, NR¹¹CR²⁴═NOR¹⁷, a cyanogroup, a nitro group, or a halogen atom,

q is 0, 1, 2 or 3, and when q is 2 or 3, a plurality of R³ may beidentical to or different from each other,

When two R³ are adjacent to each other, said two R³ may combinedtogether with a carbon atom to which they are attached to form benzenering, pyrrole ring, furan ring, thiophene ring, pyrazole ring, imidazolering, triazole ring, oxazole ring, isoxazole ring, thiazole ring,oxadiazole ring, thiadiazole ring, pyridine ring, pyridazine ring,pyrimidine ring, or pyrazine ring {the benzene ring, the pyrrole ring,the furan ring, the thiophene ring, the pyrazole ring, the imidazolering, the triazole ring, the oxazole ring, the isoxazole ring, thethiazole ring, the pyridine ring, the pyridazine ring, the pyrimidinering, and the pyrazine ring each independently may optionally have oneor more substituents selected from Group H},

R¹⁷ represents a C1-C6 chain hydrocarbon group optionally having one ormore halogen atoms, a phenyl group optionally having one or moresubstituents selected from Group D, or a hydrogen atom,

R⁸, R¹¹, R¹⁹, R²⁴, R²⁹, R³⁶, and R³⁷ are identical to or different fromeach other and each represents independently a C1-C6 chain hydrocarbongroup optionally having one or more halogen atoms, or a hydrogen atom,

R¹² represents a C1-C6 chain hydrocarbon group optionally having one ormore substituents selected from Group F, a C3-C7 cycloalkyl groupoptionally having one or more substituents selected from Group J, aC3-C7 cycloalkenyl group optionally having one or more substituentsselected from Group J, a phenyl group, a six membered heterocyclic group{the phenyl group, and the six membered heterocyclic group eachindependently may optionally have one or more substituents selected fromGroup D}, a hydrogen atom, or a S(O)₂R²³,

R²³ represents a C1-C6 chain hydrocarbon group optionally having one ormore halogen atoms, or a phenyl group optionally having one or moresubstituents selected from Group D,

R^(11a) and R^(12a) combine together with the nitrogen atom to whichthey are attached to form a three to seven membered nonaromaticheterocyclic group optionally having one or more substituents selectedfrom group E,

R¹³ represents a hydrogen atom, a C1-C6 chain hydrocarbon groupoptionally having one or more halogen atoms, a C3-C7 cycloalkyl groupoptionally having one or more halogen atoms, a (C3-C6 cycloalkyl)C1-C3alkyl group optionally having one or more halogen atoms, a phenyl groupoptionally having one or more substituents selected from Group D, or afive or six membered aromatic heterocyclic group optionally having oneor more substituents selected from Group D,

R¹⁴ represents a C1-C6 chain hydrocarbon group optionally having one ormore halogen atoms, a C3-C7 cycloalkyl group optionally having one ormore halogen atoms, a (C3-C6 cycloalkyl)C1-C3 alkyl group optionallyhaving one or more halogen atoms, or a phenyl C1-C3 alkyl group {thephenyl moiety in the phenyl C1-C3 alkyl group may optionally have one ormore substituents selected from Group D},

R¹⁵ represents a C1-C6 alkyl group optionally having one or more halogenatoms, or a hydrogen atom,

R¹⁶ represents a C1-C6 chain hydrocarbon group optionally having one ormore substituents selected from Group F, a C3-C7 cycloalkyl groupoptionally having one or more substituents selected from Group J,S(O)₂R²³ or a hydrogen atom,

x is 0 or 1,

Group A: a group consisting of a C1-C6 alkyl group optionally having oneor more halogen atoms, a C1-C6 alkoxy group optionally having one ormore halogen atoms, a halogen atom, a cyano group and a nitro group,

Group B: a group consisting of a C1-C6 alkoxy group optionally havingone or more halogen atoms, a C3-C6 alkenyloxy group optionally havingone or more halogen atoms, a C3-C6 alkynyloxy group optionally havingone or more halogen atoms, a C1-C6 alkylsulfanyl group optionally havingone or more halogen atoms, a C1-C6 alkylsulfinyl group optionally havingone or more halogen atoms, a C1-C6 alkylsulfonyl group optionally havingone or more halogen atoms, a C3-C6 cycloalkyl group optionally havingone or more halogen atoms, a cyano group, a hydroxy group, and a halogenatom,

Group D: a group consisting of a C1-C6 chain hydrocarbon groupoptionally having one or more halogen atoms, a hydroxy group, a C1-C6alkoxy group optionally having one or more halogen atoms, a C3-C6alkenyloxy group optionally having one or more halogen atoms, a C3-C6alkynyloxy group optionally having one or more halogen atoms, a sulfanylgroup, a C1-C6 alkylsulfanyl group optionally having one or more halogenatoms, a C1-C6 alkylsulfinyl group optionally having one or more halogenatoms, a C1-C6 alkylsulfonyl group optionally having one or more halogenatoms, an amino group, NR⁹R¹⁰, C(O)R¹⁰, OC(O)R⁹, C(O)OR⁹, a cyano group,a nitro group, and a halogen atom,

R⁹ represents a C1-C6 alkyl group optionally having one or more halogenatoms, or a C3-C6 cycloalkyl group optionally having one or more halogenatoms,

R¹⁰ represents a C1-C6 alkyl group optionally having one or more halogenatoms, a C3-C6 cycloalkyl group optionally having one or more halogenatoms, or a hydrogen atom,

Group E: a group consisting of a C1-C6 chain hydrocarbon groupoptionally having one or more halogen atoms, a C1-C6 alkoxy groupoptionally having one or more halogen atoms, a C3-C6 alkenyloxy groupoptionally having one or more halogen atoms, a C3-C6 alkynyloxy groupoptionally having one or more halogen atoms, a halogen atom, an oxogroup, a hydroxy group, a cyano group, and a nitro group;

Group F: a group consisting of a C3-C6 cycloalkyl group optionallyhaving one or more halogen atoms, a phenyl group or a six memberedaromatic heterocyclic group {the phenyl group and the six memberedaromatic heterocyclic group each independently may optionally have oneor more substituents selected from Group D}, OR¹⁰, an amino group,NR⁹R¹⁰, a halogen atom, a nitro group, and a cyano group;

Group H: a group consisting of a five or six membered aromaticheterocyclic group, a C1-C6 alkyl group optionally having one or morehalogen atoms, a C3-C6 cycloalkyl group optionally having one or morehalogen atoms, OR¹⁰, an amino group, NR⁹R¹⁰, C(O)R¹⁰, C(O)NR⁹R¹⁰,OC(O)R⁹, OC(O)OR⁹, NR¹⁰C(O)R⁹, NR¹⁰C(O)OR⁹, C(O)OR¹⁰, a halogen atom, anitro group, and a cyano group.

Group J: a group consisting of a C1-C6 alkyl group optionally having oneor more halogen atoms, a halogen atom, a cyano group, a triazolyl group,and NR¹⁰C(O)R⁹. (hereinafter, referred to as “Intermediate compound E”).

[27] A compound represented by formula (IV):

[wherein,

R² represents a C1-C6 alkyl group optionally having one or more halogenatoms, a cyclopropyl group or a cyclopropylmethyl group,

n is 0, 1 or 2,

R³ represents a C1-C6 chain hydrocarbon group optionally having one ormore substituents selected from Group B, a C3-C7 cycloalkyl groupoptionally having one or more substituents selected from group E, aC3-C7 cycloalkenyl group optionally having one or more substituentsselected from Group J, a phenyl group optionally having one or moresubstituents selected from Group H, a five or six membered aromaticheterocyclic group optionally having one or more substituents selectedfrom Group H, OR¹², NR¹¹R¹², NR^(11a)R^(12a), NR²⁴NR¹¹R¹², NR²⁴OR¹¹,NR¹¹C(O)R¹³, NR²⁴NR¹¹C(O)R¹³, NR¹¹C(O)OR¹⁴, NR²⁴NR¹¹C(O)OR¹⁴,NR¹¹C(O)NR¹⁵R¹⁶, NR²⁴NR¹¹C(O)NR¹⁵R¹⁶, N═CHNR¹⁵R¹⁶, N═S(O)_(x)R¹⁵R¹⁶,C(O)R¹⁷, C(O)OR¹⁷, C(O)NR¹⁵R¹⁶, CR²⁴═NOR¹⁷, NR¹¹CR²⁴═NOR¹⁷, a cyanogroup, a nitro group, or a halogen atom,

q is 0, 1, 2 or 3, and when q is 2 or 3, a plurality of R³ may beidentical to or different from each other,

When two R³ are adjacent to each other, said two R³ may combinedtogether with a carbon atom to which they are attached to form benzenering, pyrrole ring, furan ring, thiophene ring, pyrazole ring, imidazolering, triazole ring, oxazole ring, isoxazole ring, thiazole ring,oxadiazole ring, thiadiazole ring, pyridine ring, pyridazine ring,pyrimidine ring, or pyrazine ring {the benzene ring, the pyrrole ring,the furan ring, the thiophene ring, the pyrazole ring, the imidazolering, the triazole ring, the oxazole ring, the isoxazole ring, thethiazole ring, the pyridine ring, the pyridazine ring, the pyrimidinering, and the pyrazine ring each independently may optionally have oneor more substituents selected from Group H},

Het^(W) represents a group represented by the following formula Het 3 ora group represented by the following formula Het 4:

A¹ represents a nitrogen atom or CR⁶,

A² represents a nitrogen atom or CR^(4a),

A³ represents a nitrogen atom or CR^(4b),

A⁴ represents a nitrogen atom or CR^(4c),

Q¹ represents an oxygen atom or a sulfur atom,

R²⁰ represents a C1-C6 alkyl group optionally having one or more halogenatoms, or a hydrogen atom,

R⁵ represents a C1-C6 chain hydrocarbon group optionally having one ormore substituents selected from group F, a C3-C6 cycloalkyl groupoptionally having one or more substituents selected from Group J, aphenyl group optionally having one or more substituents selected fromGroup H, or a five or six membered aromatic heterocyclic groupoptionally having one or more substituents selected from Group H,

R^(4a), R^(4b) and R^(4c) are identical to or different from each otherand each represents independently a C1-C6 chain hydrocarbon groupoptionally one or more halogen atoms, a nitro group, OR¹⁸, NR¹⁸R¹⁹, acyano group, an amino group, a halogen atom, or a hydrogen atom,

R⁶ represents a hydrogen atom or a halogen atom,

X^(L) represents a halogen atom, a C1-C6 alkoxy group, a C1-C6alkylsulfanyl group, a C1-C6 alkylsulfinyl group, a C1-C6 alkylsulfonylgroup {the C1-C6 alkylsulfanyl group, the C1-C6 alkylsulfinyl group, andthe C1-C6 alkylsulfonyl group each independently may optionally have aC3-C6 cyaloalkyl group}, a C3-C6 cycloalkylsulfanyl group, a C3-C6cycloalkylsulfinyl group, a C3-C6 cycloalkylsulfonyl group, a benzyloxygroup optionally having one or more substituents selected from Group A,a C2-C7 alkylcarbonyloxy group optionally having one or more halogenatoms, a (C1-C3 alkoxy)methoxy group, or a hydroxy group,

R¹⁸ represents a C1-C6 chain hydrocarbon group optionally having one ormore halogen atoms,

R¹⁷ represents a C1-C6 chain hydrocarbon group optionally having one ormore halogen atoms, a phenyl group optionally having one or moresubstituents selected from Group D, or a hydrogen atom,

R¹¹, R¹⁹ and R²⁴ are identical to or different from each other and eachrepresents independently a C1-C6 chain hydrocarbon group optionally oneor more halogen atoms, or a hydrogen atom,

R¹² represents a C1-C6 chain hydrocarbon group optionally having one ormore substituents selected from Group F, a C3-C7 cycloalkyl groupoptionally having one or more substituents selected from Group J, aC3-C7 cycloalkenyl group optionally having one or more substituentsselected from Group J, a phenyl group, or six membered heterocyclicgroup {the phenyl group, and the six membered heterocyclic group eachindependently may have optionally one or more substituents selected fromGroup D}, a hydrogen atom, or S(O)₂R²³,

R²³ represents a C1-C6 chain hydrocarbon group optionally having one ormore halogen atoms, or a phenyl group optionally having one or moresubstituents selected from Group D,

R^(11a) and R^(12a) combine together with the nitrogen atom to whichthey are attached to form a three to seven membered nonaromaticheterocyclic group optionally having one or more substituents selectedfrom group E,

R¹³ represents a hydrogen atom, a C1-C6 Chain hydrocarbon groupoptionally having one or more halogen atoms, a C3-C7 cycloalkyl groupoptionally having one or more halogen atoms, a (C3-C6 cycloalkyl)C1-C3alkyl group optionally having one or more halogen atoms, a phenyl groupoptionally having one or more substituents selected from Group D, or afive or six membered aromatic heterocyclic group optionally having oneor more substituents selected from Group D,

R¹⁴ represents a C1-C6 chain hydrocarbon group optionally having one ormore halogen atoms, a C3-C7 cycloalkyl group optionally having one ormore halogen atoms, a (C3-C6 cycloalkyl)C1-C3 alkyl group optionallyhaving one or more halogen atoms, or a phenyl C1-C3 alkyl group {thephenyl moiety in the phenyl C1-C3 alkyl group may optionally have one ormore substituents selected from Group D},

R¹⁵ represents a C1-C6 alkyl group optionally having one or more halogenatoms, or a hydrogen atom,

R¹⁶ represents a C1-C6 chain hydrocarbon group optionally having one ormore substituents selected from Group F, a C3-C7 cycloalkyl groupoptionally having one or more substituents selected from Group J,S(O)₂R²³ or a hydrogen atom,

x is 0 or 1,

Group A; a group consisting of a C1-C6 alkyl group optionally having oneor more halogen atoms, a C1-C6 alkoxy group optionally having one ormore halogen atoms, a halogen atom, a cyano group and a nitro group,

Group B: a group consisting of a C1-C6 alkoxy group optionally havingone or more halogen atoms, a C3-C6 alkenyloxy group optionally havingone or more halogen atoms, a C3-C6 alkynyloxy group optionally havingone or more halogen atoms, a C1-C6 alkylsulfanyl group optionally havingone or more halogen atoms, a C1-C6 alkylsulfinyl group optionally havingone or more halogen atoms, a C1-C6 alkylsulfonyl group optionally havingone or more halogen atoms, a C3-C6 cycloalkyl group optionally havingone or more halogen atoms, a cyano group, a hydroxy group, and a halogenat

Group D: a group consisting of a C1-C6 chain hydrocarbon groupoptionally having one or lore halogen atoms, a hydroxy group, a C1-C6alkoxy group optionally having one or more halogen atoms, a C3-C6alkenyloxy group optionally having one or more halogen atoms, a C3-C6alkynyloxy group optionally having one or more halogen atoms, a sulfanylgroup, a C1-C6 alkylsulfanyl group optionally having one or more halogenatoms, a C1-C6 alkylsulfinyl group optionally having one or more halogenatoms, a C1-C6 alkylsulfonyl group optionally having one or more halogenatoms, an amino group, NR⁹R¹⁰, C(O)R¹⁰, OC(O)R⁹, C(O)OR⁹, a cyano group,a nitro group, and a halogen atom,

R⁹ represents a C1-C6 alkyl group optionally having one or more halogenatoms, or a C3-C5 cycloalkyl group optionally having one or more halogenatoms,

R¹⁰ represents a C1-C6 alkyl group optionally having one or more halogenatoms, a C3-C6 cycloalkyl group optionally having one or more halogenatoms, or a hydrogen atom,

Group E: a group consisting of a C1-C6 chain hydrocarbon groupoptionally having one or more halogen atoms, a C1-C6 alkoxy groupoptionally having one or more halogen atoms, a C3-C6 alkenyloxy groupoptionally having one or more halogen atoms, a C3-C6 alkynyloxy groupoptionally having one or more halogen atoms, a halogen atom, an oxogroup, a hydroxy group, a cyano group, and a nitro group;

Group F: a group consisting of a C3-C6 cycloalkyl group optionallyhaving one or more halogen atoms, a phenyl group or a six memberedaromatic heterocyclic group {the phenyl group and the six memberedaromatic heterocyclic group each independently may optionally have oneor more substituents selected from Group n}, OR¹⁰, an amino group,NR⁹R¹⁰, a halogen atom, a nitro group, and a cyano group;

Group H: a group consisting of a five or six membered aromaticheterocyclic group, a C1-C6 alkyl group optionally having one or morehalogen atoms, a C3-C6 cycloalkyl group optionally having one or morehalogen atoms, OR¹⁰, an amino group, NR⁹R¹⁰, C(O)R¹⁰, C(O)NR⁹R¹⁰,OC(O)R⁹, OC(O)OR⁹, NR¹⁰C(O)R⁹, NR¹⁰C(O)OR⁹, C(O)OR¹⁰, a halogen atom, anitro group, and a cyano group.

Group J: a group consisting of a C1-C6 alkyl group optionally having oneor more halogen atoms, a halogen atom, a cyano group, a triazolyl group,and NR¹⁰C(O)R⁹].

(hereinafter, referred to as “Intermediate compound F”).

Effect of Invention

The present invention can control harmful arthropods.

MODE FOR CARRYING OUT THE INVENTION

The substituent(s) as described herein is/are explained.

The term “halogen atom” represents fluorine atom, chlorine atom, bromineatom, or iodine atom.

When the substituents have two or more halogen atoms, these halogenatoms may be identical to or different from each other.

The expression of “CX-CY” as used herein represents that the number ofcarbon atom is from X to Y. For example, the expression of “C1-C6”represents that the number of carbon atom is from 1 to 6,

The term of “chain hydrocarbon group” represents an alkyl group, analkenyl group, or an alkynyl group.

Example of the term of “alkyl group” include methyl group, ethyl group,propyl group, isopropyl group, 1,1-dimethylpropyl group,1,2-dimethylpropyl group, 1-ethylpropyl group, butyl group, sec-butylgroup, tert-butyl group, pentyl group, hexyl group, octyl group, nonylgroup, and decyl group.

Example of the term of “alkenyl group” include vinyl group, 1-propenylgroup, 2-propenyl group, 1-methyl-1-propenyl group, 1-methyl-2-propenylgroup, 1,2-dimethyl-1-propenyl group, 1-ethyl-2-propenyl group,3-butenyl group, 4-pentenyl group, 5-hexenyl group, 7-octenyl group,8-nonenyl group, and 9-decenyl group.

Example of the term of “alkynyl group” includes ethynyl group,1-propynyl group, 2-propynyl group, 1-methyl-2-propynyl group,1,1-dimethyl-2-propynyl group, 1-ethyl-2-propynyl group, 2-butynylgroup, 4-pentynyl group, 5-hexynyl group, 7-octynyl group, 8-nonynylgroup, and 9-decynyl group.

Example of the term of “C1-C6 alkyl group optionally having one or morehalogen atoms” or “C1-C6 haloalkyl group” include trifluoromethyl group,2,2,2-trifluoroethyl group, 2-bromo-1,1,2,2-tetrafluoroethyl group,2,2,3,3-tetrafluoropropyl group, 1-methyl-2,2,3,3-tetrafluoropropylgroup, and perfluorohexyl group.

Example of the term of “cycloalkyl group” includes cyclopropyl group,cyclobutyl group, cyclopentyl group, cyclohexyl group and cycloheptylgroup.

Example of the term of “cycloalkenyl group” includes cyclopropenylgroup, cyclobutenyl group, cyclopentenyl group, cyclohexenyl group, andcycloheptenyl group. Examples of the term of “C3-C6 cycloalkyl groupoptionally having one or more halogen atoms” includes2,2-difluorocyclopropyl group, 1-(2,2,2-trifluoroethyl)cyclopropylgroup, and 4-(trifluoromethyl)cyclohexyl group.

Examples of the term of “alkoxy group” includes methoxy group, ethoxygroup, propoxy group, butoxy group, pentoxy group, and hexyloxy group.

The term of “C1-C6 alkoxy group optionally having one or more halogenatoms” represents a C1-C6 alkoxy group wherein one or more halogen atomsare replaced by a halogen atom, and includes, for example,trifluoromethoxy group, difluoromethoxy group, 2,2,2-trichloroethoxygroup, and 2,2,2-trifluoroethoxy group.

The terms of “alkylsulfanyl”, “alkylsulfinyl”, and “alkylsulfonyl”represent an alkyl group containing a S(O)_(z) moiety, respectively.

For example, examples of the “alkylsulfanyl” when z is 0 includemethylsulfanyl group, ethylsulfanyl group, propylsulfanyl group, andisopropylsulfanyl group.

For example, examples of the “alkylsulfinyl” when z is 1 includemethylsulfinyl group, ethylsulfinyl group, propylsulfinyl group, andisopropylsulfinyl group.

For example, examples of the “alkylsulfonyl” when z is includemethylsulfonyl group, ethylsulfonyl group, propylsulfonyl group, andisopropylsulfonyl group.

Examples of the term of “three (3) to seven (7) membered nonaromaticheterocyclic group” include aziridine ring, azetidine ring, pyrrolidinering, imidazoline ring, imidazolidine ring, piperidine ring,tetrahydropyrimidine ring, hexahydropyrimidine ring, piperazine ring,azepane ring, oxazolidine ring, isoxazolidine ring, 1,3-oxazinane ring,morpholine ring, 1,4-oxazepane ring, thiazolidine ring, isothiazolidinering, 1,3-thiazinane ring, thiomorpholine ring, and 1,4-thiazepane ring.Examples of the three to seven membered nonaromatic heterocyclic groupoptionally having one or more substituents selected from Group E includethe followings:

The term of “(C1-C5 alkoxy)C2-C5 alkyl group having one or mare halogenatom” represents a group wherein the (C1-C5 alkoxy) and/or the (C2-C5alkyl) has/have one or more halogen atoms, and includes, for example,2-(trifluoromethoxy)ethyl group, 2,2-difluoro-3-methoxypropyl group,2,2-difluoro-3-(2,2,2-trifluoroethoxy)propyl group, and3-(2-chloroethoxy)propyl group.

The term of “(C1-C5 alkylsulfanyl)C2-C5 alkyl group having one or morehalogen atoms” represents a group wherein the (C1-C5 alkylsulfanyl)and/or the (C2-C5 alkyl) has/have one or more halogen atoms, andincludes, for example, 2,2-difluoro-2-(trifluoromethylthio)ethyl group.

The term of “(C1-C5 alkylsulfinyl)C2-C5 alkyl group having one or morehalogen atoms” represents a group wherein the (C1-C5 alkylsulfinyl)and/or the (C2-C5 alkyl) has/have one or more halogen atoms, andincludes, for example, 2,2-difluoro-2-(trifluoromethansulfinyl)ethylgroup.

The term of “(C1-C5 alkylsulfonyl)C2-C5 alkyl group having one or morehalogen atoms” represents a group wherein the (C1-C5 alkylsulfonyl)and/or the (C2-C5 alkyl) has/have one or more halogen atoms, andincludes, for example, 2,2-difluoro-2-(trifluoromethansulfonyl) ethylgroup.

The term of “(C3-C7 cycloalkyl)C1-C3 alkyl group optionally having oneor more halogen atoms” represents a group wherein the (C3-C7 cycloalkyl)and/or the (C1-C3 alkyl) has/have one car more halogen atoms, andincludes, for example, (2,2-difluorocyclopropyl)methyl group,2-cyclopropyl-1,1,2,2-tetrafluoroethyl group, and2-(2,2-difluorocyclopropyl)-1,1,2,2-tetrafluoroethyl group.

The term of “(C3-C7 cycloalkyl)C1-C3 alkyl group having one or toresubstituents selected from Group G” represents a group wherein the(C3-C7 cycloalkyl) and/or the (C1-C3 alkyl) has/have one or moresubstituents selected from Group G, and includes, example,(2,2-difluorocyclopropyl)methyl group,[1-(trifluoromethyl)cyclopropyl]methyl group,[2-(trifluoromethyl)cyclopropyl]methyl group,2-cyclopropyl-1,1,2,2-tetrafluoroethyl group,2-cyclopropyl-3,3,3-trifluoropropyl group, and 1,1,2,2,tetrafluoro-2-[2-(trifluoromethyl)cyclopropyl]ethyl group.

Examples of the term of “phenyl C1-C3 alkyl group {the phenyl moiety inthe phenyl C1-C3 alkyl group may optionally have one or moresubstituents selected from Group D}” include benzyl group,2-fluorobenzyl group, 4-chlorobenzyl group, 4-(trifluoromethyl)benzylgroup, and 2-[4-(trifluoromethyl)phenyl]ethyl group.

The term of “five (5) or six (6) membered aromatic heterocyclic group”represents a five membered aromatic heterocyclic group or a six memberedaromatic heterocyclic group, and examples of the five membered aromaticheterocyclic group include pyrrolyl group, furyl group, thienyl group,pyrazolyl group, imidazolyl group, triazolyl group, tetrazolyl group,oxazolyl group, isoxazolyl group, thiazolyl group, isothiazolyl group,oxadiazolyl group, and thiadiazolyl group. As the five membered aromaticheterocyclic group, a five membered aromatic heterocyclic groupcontaining 1 to 4 nitrogen atoms, that is, pyrrolyl group, pyrazolylgroup, imidazolyl group, 1,2,4-triazolyl group, 1,2,3-triazolyl group,or tetrazolyl group is preferably included. Examples of the six memberedaromatic heterocyclic group include pyridyl group, pyridazinyl group,pyrimidinyl group, pyrazinyl group, and triazinyl group.

The term of “when two R³ are adjacent to each other, said two R³ combinetogether with a carbon atom to which they are attached to form benzenering, pyrrole ring, furan ring, thiophene ring, pyrazole ring, imidazolering, triazole ring, oxazole ring, isoxazole ring, thiazole ring,oxadiazole ring, thiadiazole ring, pyridine ring, pyridazine ring,pyrimidine ring, or pyrazine ring” represents, for example, thefollowing compounds when pyrrole ring is formed.

(wherein, R^(Ha), R^(Hb), and R^(Hc) are identical to or different fromeach other and each represents independently a five or six memberedaromatic heterocyclic group, a C1-C6 alkyl group optionally having oneor more halogen atoms, a C3-C6 cycloalkyl group optionally having one ormore halogen atoms, OR¹⁰, an amino group, NR⁹R¹⁰, C(O)R¹⁰, C(O)NR⁹R¹⁰,OC(O)R⁹, OC(O)CR⁹, NR¹⁰C(O)R⁹, NR¹⁰C(O)OR⁹, C(O)OR¹⁰, a halogen atom, anitro group, or a cyano group, and the other symbols are the same asdefined above.]

Examples of the embodiment of the compound of the present inventioninclude the following compounds.

When “Present compound Z of the present invention” is described herein,encompasses “Present compound of the present invention” unless specifiedotherwise.

Embodiment 1

A compound of the present invention wherein A¹ represents a nitrogenatom or CH.

Embodiment 2

The compound described in Embodiment 1 wherein R² represents an ethylgroup, R³ represents a C1-C6 alkyl group optionally having one or moresubstituents selected from Group B, a C3-C7 cycloalkyl group optionallyhaving one or more substituents selected from Group E, a phenyl group, apyridyl group, a pyrimidinyl group, a pyrazolyl group, a triazolyl group{the phenyl group, the pyridyl group, the pyrimidinyl group, thepyrazolyl group, and the triazolyl group each independently mayoptionally have one or more substituents selected from Group J}, OR¹²,NR¹¹R¹², NR¹¹C(O)OR¹⁴ or a halogen atom, R^(4a), R^(4b) and R^(4c)represent a hydrogen atom, R⁵ represents a C1-C6 alkyl group optionallyhaving one or more halogen atoms, q is 0 or 1, and Q¹ and Q² representan oxygen atom.

Embodiment 3

A compound of the present invention wherein A¹ represents a nitrogenatom.

Embodiment 4

The compound described in Embodiment 3 wherein R³ represents a C1-C6alkyl group optionally having one or more substituents selected fromGroup B, a C3-C7 cycloalkyl group optionally having one or moresubstituents selected from Group E, a phenyl group, a pyridyl group, apyrimidinyl group, a pyrazolyl group, a triazolyl group {the phenylgroup, the pyridyl group, the pyrimidinyl group, the pyrazolyl group,and the triazolyl group each independently may optionally have one ormore substituents selected from Group J}, OR¹², NR¹¹R¹², NR¹¹C(O)OR¹⁴,or a halogen atom.

Embodiment 5

The compound described in Embodiment 3 wherein R² represents a C1-C6alkyl group, R^(4a), R^(4b) and R^(4c) represent a hydrogen atom or ahalogen atom, q is 0 or 1, and Q¹ and Q² represent an oxygen atom.

Embodiment 6

The compound described in Embodiment 5 wherein R³ represents a C1-C6alkyl group optionally having one or more substituents selected fromGroup B, a C3-C7 cycloalkyl group optionally having one or moresubstituents selected from Group E, a phenyl group, a pyridyl group, apyrimidinyl group, a pyrazolyl group, a triazolyl group {the phenylgroup, the pyridyl group, the pyrimidinyl group, the pyrazolyl group,and the triazolyl group each independently may optionally have one ormore substituents selected from Group J}, OR¹², NR¹¹R¹², NR¹¹C(O)OR¹⁴ ora halogen atom, and R⁵ represents a C1-C6 alkyl group optionally havingone or more halogen atoms.

Embodiment 7

The compound described in Embodiment 3 wherein R² represents a C1-C6alkyl group, R³ represents a C1-C6 alkyl group, C3-C7 cycloalkyl group{the C1-C6 alkyl group and the C3-C7 cycloalkyl group each independentlymay optionally have one or more substituents selected from the groupconsisting of a halogen atom and a cyano group}, a phenyl group, apyridyl group {the phenyl group and the pyridyl group each independentlymay optionally have one or more substituents selected from Group G}, ora halogen atom, R^(4a), R^(4b) and R^(4c) represent a hydrogen atom, R⁵represents a C1-C6 alkyl group optionally having one or more halogenatoms, q is 0 or 1, and Q¹ and Q² represent an oxygen atom.

Embodiment 8

A compound of the present invention wherein A¹ represents CH.

Embodiment 9

The compound described in Embodiment 8 wherein R² represents an ethylgroup, R³ represents a C1-C6 alkyl group optionally having one or moresubstituents selected from Group B, a C3-C7 cycloalkyl group optionallyhaving one or more substituents selected from Group E, a phenyl group, apyridyl group, a pyrimidinyl group, a pyrazolyl group, a triazolyl group{the phenyl group, the pyridyl group, the pyrimidinyl group, thepyrazolyl group, and the triazolyl group each independently mayoptionally have one or more substituents selected from Group J}, OR¹²,NR¹¹R¹², NR¹¹C(O)OR¹⁴, or a halogen atom, R^(4a), R^(4b) and R^(4c)represent a hydrogen atom, R⁵ represents a C1-C6 alkyl group optionallyhaving one or more halogen atoms, q is 0 or 1, and Q¹ and Q² representan oxygen atom.

Embodiment 10

A compound of the present invention wherein Het represents Het 1.

Embodiment 11

The compound described in Embodiment 10 wherein A¹ represents a nitrogenatom or CH.

Embodiment 12

The compound described in Embodiment 11 wherein R² represents an ethylgroup, R³ represents a C1-C6 alkyl group optionally having one or moresubstituents selected from Group B, a C3-C7 cycloalkyl group optionallyhaving one or more substituents selected from Group E, a phenyl group, apyridyl group, a pyrimidinyl group, a pyrazolyl group, a triazolyl group{the phenyl group, the pyridyl group, the pyrimidinyl group, thepyrazolyl group, and the triazolyl group each independently mayoptionally have one or more substituents selected from Group J}, OR¹²,NR¹¹R¹², NR¹¹C(O) OR¹⁴, or a halogen atom, R^(4a) and R^(4b) represent ahydrogen atom, R⁵ represents a C1-C6 alkyl group optionally having oneor more halogen atoms, q is 0 or 1, and Q¹ and Q² represent an oxygenatom.

Embodiment 13

The compound described in Embodiment 10 wherein A¹ represents a nitrogenatom.

Embodiment 14

The compound described in Embodiment 13 wherein R³ represents a C1-C6alkyl group optionally having one or more substituents selected fromGroup B, a C3-C7 cycloalkyl group optionally having one or moresubstituents selected from Group E, a phenyl group, a pyridyl group, apyrimidinyl group, a pyrazolyl group, a triazolyl group {the phenylgroup, the pyridyl group, the pyrimidinyl group, the pyrazolyl group,and the triazolyl group each independently may optionally have one ormore substituents selected from Group J}, OR¹², NR¹¹R¹², NR¹¹C(O) OR¹⁴or a halogen atom.

Embodiment 15

The compound described in Embodiment wherein R² represents a C1-C6 alkylgroup, R^(4a) and R^(4b) represent a hydrogen atom or a halogen atom, qis 0 or 1, and Q¹ and Q² represent an oxygen atom.

Embodiment 16

The compound described in Embodiment 15 wherein R³ represents a C1-C6alkyl group optionally having one or more substituents selected fromGroup B, a C3-C7 cycloalkyl group optionally having one or moresubstituents selected from Group E, a phenyl group, a pyridyl group,pyrimidinyl group, a pyrazolyl group, a triazolyl group {the phenylgroup, the pyridyl group, the pyrimidinyl group, the pyrazolyl group,and the triazolyl group each independently may optionally have one ormore substituent: selected from Group J}, OR¹², NR¹¹R¹², NR¹¹C(O)OR¹⁴,or a halogen atom, and R⁵ represents a C1-C6 alkyl group optionallyhaving one or more halogen atoms.

Embodiment 17

The compound described in Embodiment 13 wherein R² represents a C1-C6alkyl group, R³ represents a C1-C6 alkyl group, a C3-C7 cycloalkyl group{the C1-CG alkyl group and the C3-C7 cycloalkyl group each independentlymay optionally have one or more substituents selected from the groupconsisting of a halogen atom and a cyano group}, a phenyl group, apyridyl group {the phenyl group, and the pyridyl group eachindependently may optionally have one or more substituents selected fromGroup G}, or a halogen atom, R^(4a) and R^(4b) represent a hydrogenatom, R⁵ represents a C1-C6 alkyl group optionally having one or morehalogen atoms, q is 0 or 1, and Q¹ and Q² represent an oxygen atom.

Embodiment 18

The compound described in Embodiment 10 wherein A¹ represents CH.

Embodiment 19

The compound described in Embodiment 18 wherein R² represents an ethylgroup, R³ represents a C1-C6 alkyl optionally having one or moresubstituents selected from group B, a C3-C7 cycloalkyl group optionallyhaving one or more substituents selected from Group E, a phenyl group, apyridyl group, a pyrimidinyl group, a pyrazolyl group, a triazolyl group{the phenyl group, the pyridyl group, the pyrimidinyl group, thepyrazolyl group, and the triazolyl group each independently mayoptionally have one or more substituents selected from Group J}, OR¹²,NR¹¹R¹², NR¹¹C(O)OR¹⁴, or a halogen atom, R^(4a) and R^(4b) represent ahydrogen atom, R⁵ represents a C1-C6 alkyl group optionally having oneor more halogen atoms, q is 0 or 1, and Q¹ and Q² represent an oxygenatom.

Embodiment 20

The compound described in Embodiment 10 wherein A² represents CR^(4a),and A³ represents CR^(4b).

Embodiment 21

The compound described in Embodiment 11 wherein A² represents CR^(4a)and A³ represents CR^(4b).

Embodiment 22

The compound described in Embodiment 12 wherein A² represents CR^(4a)and A³ represents CR^(4b).

Embodiment 23

The compound described in Embodiment 13 wherein A² represents CR^(4a)and A³ represents CR^(4b).

Embodiment 24

The compound described in Embodiment 14 wherein A² represents CR^(4a)and A³ represents CR^(4b).

Embodiment 25

The compound described in Embodiment 15 wherein A² represents CR^(4a)and A³ represents CR^(4b).

Embodiment 26

The compound described in Embodiment 16 wherein A² represents CR^(4a)and A³ represents CR^(4b).

Embodiment 27

The compound described in Embodiment 17 wherein A² represents CR^(4a)and A³ represents CR^(4b).

Embodiment 28

The compound described in Embodiment 18 wherein A² represents CR^(4a)and A³ represents CR^(4b).

Embodiment 29

The compound described in Embodiment 19 wherein A² represents CR^(4a)and A³ represents CR^(4b).

Embodiment 30

A compound of the present invention wherein Het represents a grouprepresented by formula Het 1, A² represents CR^(4a), and A³ represents anitrogen atom.

Embodiment 31

The compound described in Embodiment 30 wherein A¹ represents a nitrogenatom or CH.

Embodiment 32

The compound described in Embodiment 31 wherein R² represents an ethylgroup, R³ represents a C1-C6 alkyl group optionally having one or moresubstituents selected from Group B, a C3-C7 cycloalkyl group optionallyhaving one or more substituents selected from Group E, a phenyl group, apyridyl group, a pyrimidinyl group, a pyrazolyl group, a triazolyl group{the phenyl group, the pyridyl group, the pyrimidinyl group, thepyrazolyl group, and the triazolyl group each independently mayoptionally have one or more substituents selected from Group J}, OR¹²,NR¹¹R¹², NR¹¹C(O)OR¹⁴, or a halogen atom, R^(4a) represents a hydrogenatom, R⁵ represents a C1-C6 alkyl group optionally having one or morehalogen atoms, q is 0 or 1, and Q¹ and Q² represent an oxygen atom.

Embodiment 33

The compound described in Embodiment 30 wherein A¹ represents a nitrogenatom.

Embodiment 34

The compound described in Embodiment 33 wherein R³ represents a C1-C6alkyl group optionally having one or more substituents selected fromGroup B, a 03-C7 cycloalkyl group optionally having one or moresubstituents selected from Group E, a phenyl group, a pyridyl group, apyrimidinyl group, a pyrazolyl group, a triazolyl group {the phenylgroup, the pyridyl group, the pyrimidinyl group, the pyrazolyl group,and the triazolyl group each independently may optionally have one ormore substituents selected from Group J}, OR¹², NR¹¹R¹², NR¹¹C(O)OR¹⁴,or a halogen atom.

Embodiment 35

The compound described in Embodiment 33 wherein R² represents a C1-C6alkyl group, R^(4a) represents a hydrogen atom or a halogen atom, q is 0or 1, and Q¹ and Q² represent an oxygen atom.

Embodiment 36

The compound described in Embodiment 35 wherein R³ represents a C1-C6alkyl group optionally having one or more substituents selected fromGroup B, a C3-C7 cycloalkyl group optionally having one or moresubstituents selected from group E, a phenyl group, a pyridyl group, apyrimidinyl group, a pyrazolyl group, a triazolyl group {the phenylgroup, the pyridyl group, the pyrimidinyl group, the pyrazolyl group,and the triazolyl group each independently may optionally have one ormore substituents selected from group J}, OR¹², NR¹¹R¹², NR¹¹C(O) OR¹⁴,or a halogen atom, and R⁵ represents a C1-C6 alkyl group optionallyhaving one or more halogen atoms.

Embodiment 37

The compound described in Embodiment 33 wherein R² represents a C1-C6alkyl group, R³ represents a C1-C6 alkyl group, a C3-C7 cycloalkyl group{the C1-C6 alkyl group and the C3-C7 cycloalkyl group each independentlymay optionally have one or more substituents selected from the groupconsisting of a halogen atom and a cyano group}, a phenyl group, apyridyl group {the phenyl group and the pyridyl group each independentlymay optionally have one or more substituents selected from Group G}, ora halogen atom, R^(4a) represents a hydrogen atom, R⁵ represents a C1-C6alkyl group optionally having one or more halogen atoms, q is 0 or 1,and Q¹ and Q² represent an oxygen atom.

Embodiment 38

The compound described in Embodiment 30 wherein A¹ represents CH.

Embodiment 39

The compound described in Embodiment 38 wherein R² represents an ethylgroup, R³ represents a C1-C6 alkyl group optionally having one or moresubstituents selected from group B, a C3-C7 cycloalkyl group optionallyhaving one or more substituents selected from Group E, a phenyl group, apyridyl group, a pyrimidinyl group, a pyrazolyl group, triazolyl groupthe {the phenyl group, the pyridyl group, the pyrimidinyl group, thepyrazolyl group, and the triazolyl group each independently mayoptionally have one or more substituents selected from group J}, OR¹²,NR¹¹R¹², NR¹¹C(O)OR¹⁴, or a halogen atom, R^(4a) represents a hydrogenatom, R⁵ represents a C1-C6 alkyl group optionally having one or morehalogen atoms, q is 0 or 1, and Q¹ and Q² represent an oxygen atom.

Embodiment 40

A compound of the present invention wherein Het represents a grouprepresented by formula Het1, A² represents a nitrogen atom, and A³represents CR^(4b).

Embodiment 41

The compound described in Embodiment 40 wherein A¹ represents a nitrogenatom or a CH.

Embodiment 42

The compound described in Embodiment 41 wherein R² represents an ethylgroup, R³ represents a C1-C6 alkyl group optionally having one or moresubstituents selected from Group B, a C3-C7 cycloalkyl group optionallyhaving one or more substituents selected from Group E, a phenyl group, apyridyl group, a pyrimidinyl group, a pyrazolyl group, a triazolyl group{the phenyl group, the pyridyl group, the pyrimidinyl group, thepyrazolyl group, and the triazolyl group each independently mayoptionally have one or more substituents selected from Group J}, OR¹²,NR¹¹R¹², NR¹¹C(O)OR¹⁴, or a halogen atom, R^(4b) represents a hydrogenatom, R⁵ represents a C1-C6 alkyl group optionally having one or morehalogen atoms, q is 0 or 1, and Q¹ and Q² represent an oxygen atom.

Embodiment 43

The compound described in Embodiment 40 wherein A¹ represents a nitrogenatom.

Embodiment 44

The compound described in Embodiment 43 wherein R³ represents a C1-C6alkyl group optionally having one or more substituents selected fromGroup B, a C3-C7 cycloalkyl group optionally having one or moresubstituents selected from Group E, a phenyl group, a pyridyl group, apyrimidinyl group, a pyrazolyl group, a triazolyl group {the phenylgroup, the pyridyl group, the pyrimidinyl group, the pyrazolyl group,and the triazolyl group each independently may optionally have one ormore substituents selected from Group J}, OR¹², NR¹¹R¹², NR¹¹C(O)OR¹⁴,or a halogen atom.

Embodiment 45

The compound described in Embodiment 43 wherein R² represents a C1-C6alkyl group, R^(4b) represents a hydrogen atom or a halogen atom, q is 0or 1, and Q¹ and Q² represent an oxygen atom.

Embodiment 46

The compound described in Embodiment 45 wherein R³ represents a C1-C6alkyl group optionally having one or ore substituents selected fromGroup B, a C3-C7 cycloalkyl group optionally having one or moresubstituents selected from Group E, a phenyl group, a pyridyl group apyrimidinyl group, a pyrazolyl group, a triazolyl group {the phenylgroup, the pyridyl group, the pyrimidinyl group, the pyrazolyl group,and the triazolyl group each independently may optionally have one ormore substituents selected from Group J}, OR¹², NR¹¹R¹², NR¹¹C(O) OR¹⁴,or a halogen atom, and R⁵ represents a C1-C6 alkyl group optionallyhaving one or more halogen atoms.

Embodiment 47

The compound described in Embodiment 43 wherein R² represents a C1-C6alkyl group, R³ represents a C1-C6 alkyl group, a C3-C7 cycloalkyl group{the C1-C6 alkyl group and the C3-C7 cycloalkyl group each independentlymay optionally have one or more substituents selected from the groupconsisting of a halogen atom and a cyano group}, a phenyl group, apyridyl group {the phenyl group and the pyridyl group each independentlymay optionally have one or more substituents selected from Group G}, ora halogen atom, R^(4b) represents a hydrogen atom, R⁵ represents a C1-C6alkyl group optionally having one or more halogen atoms, q is 0 or 1,and Q¹ and Q² represent an oxygen atom.

Embodiment 48

The compound described in Embodiment 40 wherein A¹ represents CH.

Embodiment 49

The compound described in Embodiment 48 wherein R² represents an ethylgroup, R³ represents a C1-C6 alkyl group optionally having one or moresubstituents selected from Group B, a C3-C7 cycloalkyl group optionallyhaving one or more substituents selected from Group E, a phenyl group, apyridyl group, a pyrimidinyl group, a pyrazolyl group, a triazolyl group{the phenyl group, the pyridyl group, the pyrimidinyl group, thepyrazolyl group, and the triazolyl group each independently mayoptionally have one or more substituents selected from Group J}, OR¹²,NR¹¹R¹², NR¹¹C(O)OR¹⁴, or halogen atom, R^(4b) represents a hydrogenatom, R⁵ represents a C1-C6 alkyl group optionally having one or morehalogen atoms, q is 0 or 1, and Q¹ and Q² represent an oxygen atom.

Embodiment 50

A compound of the present invention wherein Het represents a grouprepresented by formula Het1, and A² and A³ represent a nitrogen atom.

Embodiment 51

The compound described in Embodiment 50 wherein A¹ represents a nitrogenatom or CH.

Embodiment 52

The compound described in Embodiment 51 wherein R² represents an ethylgroup, R³ represents a C1-C6 alkyl group optionally having one or moresubstituents selected from Group B, a C3-C7 cycloalkyl group optionallyhaving one or more substituents selected from Group E, a phenyl group, apyridyl group, a pyrimidinyl group, a pyrazolyl group, a triazolyl group{the phenyl group, the pyridyl group, the pyrimidinyl group, thepyrazolyl group, and the triazolyl group each independently mayoptionally have one or more substituents selected from Group L}, OR¹²,NR¹¹R¹², NR¹¹C(O)OR¹⁴, or a halogen atom, R⁵ represents a C1-C6 alkylgroup optionally having one or more halogen atoms, q is 0 or 1, and Q¹and Q² represent an oxygen atom.

Embodiment 53

The compound described in Embodiment 50 wherein A¹ represent a nitrogenatom.

Embodiment 54

The compound described in Embodiment 53 wherein R³ represents a C1-C6alkyl group optionally having one or more substituents selected fromGroup B, a C3-C7 cycloalkyl group optionally having one or moresubstituents selected from Group E, a phenyl group, a pyridyl group, apyrimidinyl group, a pyrazolyl group, a triazolyl group {the phenylgroup, the pyridyl group, the pyrimidinyl group, the pyrazolyl group,and the triazolyi group each independently may optionally have one ormore substituents selected from Group J}, OR¹², NR¹¹R¹², NR¹¹C(O)OR¹⁴,or a halogen atom.

Embodiment 55

The compound described in Embodiment 53 wherein R² represent, a C1-C6alkyl group, q is 0 or 1, and Q¹ and Q² represent an oxygen atom.

Embodiment 56

The compound described in Embodiment 55 wherein R³ represents a C1-C6alkyl group optionally having one or more substituents selected fromGroup B, or a C3-C7 cycloalkyl group optionally having one or moresubstituents selected from Group E, a phenyl group, a pyridyl group, apyrimidinyl group, a pyrazolyl group, a triazolyl group {the phenylgroup, the pyridyl group, the pyrimidinyl group, the pyrazolyl group,and the triazolyl group each independently may optionally have one ormore substituents selected from Group J}, OR¹², NR¹¹R¹², NR¹¹C(O)OR¹⁴,or a halogen atom, and R⁵ represents a C1-C6 alkyl group optionallyhaving one or more halogen atoms.

Embodiment 57

The compound described in Embodiment 53 wherein R² represents a C1-C6alkyl group, R³ represents a C1-C6 alkyl group, a C3-C7 cycloalkyl group{the C1-C6 alkyl group and the C3-C7 cycloalkyl group each independentlymay optionally have one or more substituents selected from the groupconsisting of a halogen atom and a cyano group}, a phenyl group, apyridyl group {the phenyl group and the pyridyl group each independentlymay optionally have one or more substituents selected from Group G}, ora halogen atom, R⁵ represents a C1-C6 alkyl group optionally having oneor more halogen atoms, q is 0 or 1, and Q¹ and Q² represent an oxygenatom.

Embodiment 58

The compound described in Embodiment 50 wherein A¹ represents CH.

Embodiment 59

The compound described in Embodiment 58 wherein R² represents an ethylgroup, R³ represents a C1-C6 alkyl group optionally having one or moresubstituents selected from Group B, a C3-C7 cycloalkyl group optionallyhaving one or more substituents selected from Group E, a phenyl group, apyridyl group, a pyrimidinyl group, pyrazolyl group, a triazolyl group{the phenyl group, the pyridyl group, the pyrimidinyl group, thepyrazolyl group, and the triazolyl group each independently mayoptionally have one or more substituents selected from Group J}, OR¹²,NR¹¹R¹², NR¹¹C(O)OR¹⁴, or a halogen atom, R⁵ represents a C1-C6 alkylgroup optionally having one or more halogen atoms, q is 0 or 1, and Q¹and Q² represent an oxygen atom.

Embodiment 60

A compound of the present invention wherein Het represents a grouprepresented by formula Het2.

Embodiment 61

The compound described in Embodiment 60 wherein A¹ represents a nitrogenatom or CH.

Embodiment 62

The compound described in Embodiment 61 wherein R² represents an ethylgroup, R³ represents a C1-C6 alkyl group optionally having one or moresubstituents selected from Group B, a C3-C7 cycloalkyl group optionallyhaving one or more substituents selected from Group E, a phenyl group, apyridyl group, a pyrimidinyl group, pyrazolyl group, a triazolyl group{the phenyl group, the pyridyl group, the pyrimidinyl group, thepyrazolyl group, and the triazolyl group each independently mayoptionally have one or more substituents selected from Group J}, OR¹²,NR¹¹R¹², NR¹¹C(O)OR¹⁴, or a halogen atom, R^(4a) and R^(4c) represent ahydrogen atom, R⁵ represents a C1-C6 alkyl group optionally having oneor more halogen atoms, q is 0 or 1, and Q¹ and Q² represent an oxygenatom.

Embodiment 63

The compound described in Embodiment 60 wherein A¹ represents a nitrogenatom.

Embodiment 64

The compound described in Embodiment 63 wherein R³ represents a C1-C6alkyl group optionally having one or more substituents selected fromGroup B, a C3-C7 cycloalkyl group optionally having one or moresubstituents selected from Group E, a phenyl group, a pyridyl group,pyrimidinyl group, a pyrazolyl group, a triazolyl group {the phenylgroup, the pyridyl group, the pyrimidinyl group, the pyrazolyl group,and the triazolyl group each independently may optionally have one ormore substituents selected from Group J}, OR¹², NR¹¹R¹², NR¹¹C(O)OR¹⁴,or a halogen atom.

Embodiment 65

The compound described in Embodiment 63 wherein R² represents a C1-C6alkyl group, R^(4a) and R^(4c) represent a hydrogen atom or a halogenatom, q is 0 or 1, and Q¹ and Q² represent an oxygen atom.

Embodiment 66

The compound described in Embodiment 65 wherein R³ represents a C1-C6alkyl group optionally having one or more substituents selected fromGroup B, a C3-C7 cycloalkyl group optionally having one or poresubstituents selected from Group E, a phenyl group, a pyridyl group, apyrimidinyl group, a pyrazolyl group, a triazolyl group {the phenylgroup, the pyridyl group, the pyrimidinyl group, the pyrazolyl group,and the triazolyl group each independently may optionally have one ormore substituents selected from Group J}, OR¹², NR¹¹R¹², NR¹¹C(O)OR¹⁴,or a halogen atom, and R⁵ represents a C1-C6 alkyl group optionallyhaving one or more halogen atoms.

Embodiment 67

The compound described in Embodiment 63 wherein R² represents a C1-C6alkyl group, R³ represents a C1-C6 alkyl group, a C3-C7 cycloalkyl group{the C1-C6 alkyl group and the C3-C7 cycloalkyl group each independentlymay optionally have one or more substituents selected from the groupconsisting of a halogen atom and a cyano group}, a phenyl group, apyridyl group {the phenyl group and the pyridyl group each independentlymay optionally have one or more substituents selected from Group G}, ora halogen atom, R^(4a) and R^(4c) represent a hydrogen atom, R⁵represents a C1-C6 alkyl group optionally having one or more halogenatoms, q is 0 or 1, and Q¹ and Q² represent an oxygen atom.

Embodiment 68

The compound described in Embodiment 60 wherein A¹ represents a CH.

Embodiment 69

The compound described in Embodiment 68 wherein R² represents an ethylgroup, R³ represents a C1-C6 alkyl group optionally having one or moresubstituents selected from Group B, a C3-C7 cycloalkyl group optionallyhaving one or more substituents selected from Group E, a phenyl group, apyridyl group, a pyrimidinyl group, a pyrazolyl group, a triazolyl group{the phenyl group, the pyridyl group, the pyrimidinyl group, thepyrazolyl group, and the triazolyl group each independently mayoptionally have one or more substituents selected from Group J}, OR¹²,NR¹¹R¹², NR¹¹C(O)OR¹⁴, or a halogen atom, R^(4a) and R^(4c) represent ahydrogen atom, R⁵ represents a C1-C6 alkyl group optionally having oneor more halogen atoms, q is 0 or 1, and Q¹ and Q² represent an oxygenatom.

Embodiment 70

The compound described in Embodiment 60 wherein A² represents CR^(4a)and A⁴ represents CR^(4c).

Embodiment 71

The compound described in Embodiment 61 wherein A² represents CR^(4a)and A⁴ represents CR^(4c).

Embodiment 72

The compound described in Embodiment 62 wherein A² represents CR^(4a)and A⁴ represents CR^(4c).

Embodiment 73

The compound described in Embodiment 63 wherein A² represents CR^(4a)and A⁴ represents CR^(4c).

Embodiment 74

The compound described in Embodiment 64 wherein A² represents CR^(4a)and A⁴ represents CR^(4c).

Embodiment 75

The compound described in Embodiment 65 wherein A² represents CR^(4a)and A⁴ represents CR^(4c).

Embodiment 76

The compound described in Embodiment 66 wherein A² represents CR^(4a)and A⁴ represents CR^(4c).

Embodiment 77

The compound described in Embodiment 67 wherein A² represents CR^(4a)and A⁴ represents CR^(4c).

Embodiment 78

The compound described in Embodiment 68 wherein A² represents CR^(4a)and A⁴ represents CR^(4c).

Embodiment 79

The compound described in Embodiment 69 wherein A² represents CR^(4a)and A⁴ represents CR^(4c).

Embodiment 80

A compound of the present invention wherein Het represents a grouprepresented by formula Het2, A² represents CR^(4a) and A⁴ represents anitrogen atom.

Embodiment 81

The compound described in Embodiment 80 wherein A¹ represents a nitrogenatom or CH.

Embodiment 82

The compound described in Embodiment 81 wherein R² represents an ethylgroup, R³ represents a C1-C6 alkyl group optionally having one or moresubstituents selected from Group B, a C3-C7 cycloalkyl group optionallyhaving one or more substituents selected from Group E, a phenyl group, apyridyl group, a pyrimidinyl group, a pyrazolyl group, a triazolyl group{the phenyl group, the pyridyl group, the pyrimidinyl group, thepyrazolyl group, and the triazolyl group each independently mayoptionally have one or more substituents selected from Group J}, OR¹²,NR¹¹R¹², NR¹¹C(O)OR¹⁴, or a halogen atom, R^(4a) represents a hydrogenatom, R⁵ represents a C1-C6 alkyl group optionally having one or morehalogen atoms, q is 0 or 1, and Q¹ and Q² represent an oxygen atom.

Embodiment 83

The compound described in Embodiment 80 wherein A¹ represents a nitrogenatom.

Embodiment 84

The compound described in Embodiment 83 wherein R³ represents a C1-C6alkyl group optionally having one or more substituents selected fromGroup B, a C3-C7 cycloalkyl group optionally having one or moresubstituents selected from Group E, a phenyl group, a pyridyl group, apyrimidinyl group, a pyrazolyl group, a triazolyl group {the phenylgroup, the pyridyl group, the pyrimidinyl group, the pyrazolyl group,and the triazolyl group each independently may optionally have one ormore substituents selected from Group J}, OR¹², NR¹¹R¹², NR¹¹C(O)OR¹⁴,or a halogen atom.

Embodiment 85

The compound described in Embodiment 83 wherein R² represents a C1-C6alkyl group, R^(4a) represents a hydrogen atom or a halogen atom, q is 0or 1, Q¹ and Q² represent an oxygen atom.

Embodiment 86

The compound described in Embodiment 85 wherein R³ represents a C1-C6alkyl group optionally having one or more substituents selected fromGroup B, a C3-C7 cycloalkyl group optionally having one or moresubstituents selected from Group E, a phenyl group, a pyridyl group, apyrimidinyl group, a pyrazolyl group, a triazolyl group {the phenylgroup, the pyridyl group, the pyrimidinyl group, the pyrazolyl group,and the triazolyl group each independently may optionally have one ormore substituents selected from Group J}, OR¹², NR¹¹R¹², NR¹¹C(O)OR¹⁴,or a halogen atom, R⁵ represents a C1-C6 alkyl group optionally havingone or more halogen atoms.

Embodiment 87

The compound described in Embodiment 83 wherein R² represents a C1-C6alkyl group, R³ represents a C1-C6 alkyl group, a C3-C7 cycloalkyl group{the C1-C6 alkyl group and the C3-C7 cycloalkyl group each independentlymay optionally have one or more substituents selected from the groupconsisting of a halogen atom and a cyano group}, a phenyl group, apyridyl group {the phenyl group and the pyridyl group each independentlymay optionally have one or more substituents selected from Group G}, ora halogen atom, R^(4a) represents a hydrogen atom, R⁵ represents a C1-C6alkyl group optionally having one or more halogen atoms, q is 0 or 1,and Q¹ and Q² represent an oxygen atom.

Embodiment 88

The compound described in Embodiment 80 wherein A¹ represents CH.

Embodiment 89

The compound described in Embodiment 88 wherein R² represents an ethylgroup, R³ represents a C1-C6 alkyl group optionally having one or moresubstituents selected from Group B, a C3-C7 cycloalkyl group optionallyhaving one or more substituents selected from Group E, a phenyl group,pyridyl group, a pyrimidinyl group, a pyrazolyl group, a triazolyl group{the phenyl group, the pyridyl group, the pyrimidinyl group, thepyrazolyl group, and the triazolyl group each independently mayoptionally have one or more substituents selected from Group J}, OR¹²,NR¹¹R¹², NR¹¹C(O)OR¹⁴, or a halogen atom, R^(4a) represents a hydrogenatom, R⁵ represents a C1-C6 alkyl group optionally having one or morehalogen atoms, q is 0 or 1, and Q¹ and Q² represent an oxygen atom.

Embodiment 90

A compound of the present invention wherein Het represents a grouprepresented by formula Het2, A² represents a nitrogen atom, and A⁴represents CR^(4c).

Embodiment 91

The compound described in Embodiment 90 wherein A¹ represents a nitrogenatom or CH.

Embodiment 92

The compound described in Embodiment 91 wherein R² represents an ethylgroup, R³ represents a C1-C6 alkyl group optionally having one or moresubstituents selected from Group B, a C3-C7 cycloalkyl group optionallyhaving one or more substituents selected from Group E, a phenyl group, apyridyl group, a pyrimidinyl group, a pyrazolyl group, a triazolyl group{the phenyl group, the pyridyl group, the pyrimidinyl group, thepyrazolyl group, and the triazolyl group each independently mayoptionally have one or more substituents selected from Group J}, OR¹²,NR¹¹R¹², NR¹¹C(O)OR¹⁴, or a halogen atom, R^(4c) represents a hydrogenatom, R⁵ represents a C1-C6 alkyl group optionally having one or morehalogen atoms, q is 0 or 1, and Q¹ and Q² represent an oxygen atom.

Embodiment 93

The compound described in Embodiment 90 wherein A¹ represents a nitrogenatom.

Embodiment 94

The compound described in Embodiment 93 wherein R³ represents a C1-C6alkyl group optionally having one or more substituents selected fromGroup B, a C3-C7 cycloalkyl group optionally having one or moresubstituents selected from Group E, a phenyl group, a pyridyl group, apyrimidinyl group, a pyrazolyl group, a triazolyl group {the phenylgroup, the pyridyl group, the pyrimidinyl group, the pyrazolyl group,and the triazolyl group each independently may optionally have one ormore substituents selected from Group J}, OR¹², NR¹¹R¹², NR¹¹C(O)OR¹⁴,or a halogen atom.

Embodiment 95

The compound described in Embodiment 93 wherein R² represents a C1-C6alkyl group, R^(4c) represents a hydrogen atom or a halogen atom, q is 0or 1, and Q¹ and Q² represent an oxygen atom.

Embodiment 96

The compound described in Embodiment 95 wherein R³ represents a C1-C6alkyl group optionally having one or more substituents selected fromGroup B, a C3-C7 cycloalkyl group optionally having one or moresubstituents selected from Group E, a phenyl group, a pyridyl group, apyrimidinyl group, a pyrazolyl group, a triazolyl group {the phenylgroup, the pyridyl group, the pyrimidinyl group, the pyrazolyl group,and the triazolyl group each independently may optionally have one ormore substituents selected from Group J}, OR¹², NR¹¹R¹², NR¹¹C(O)OR¹⁴,or a halogen atom, R⁵ represents a C1-C6 alkyl group optionally havingone or more halogen atoms, and Q¹ and Q² represent an oxygen atom.

Embodiment 97

The compound described in Embodiment 93 wherein R² represents a C1-C6alkyl group, R³ represents a C1-C6 alkyl group, a C3-C7 cycloalkyl group{the C1-C6 alkyl group and the C3-C7 cycloalkyl group each independentlymay optionally have one or more substituents selected from the groupconsisting of a halogen atom and a cyano group}, a phenyl group, apyridyl group {the phenyl group and the pyridyl group each independentlymay optionally have one or more substituents selected from Group G}, ora halogen atom, R^(4c) represents a hydrogen atom, R⁵ represents a C1-C6alkyl group optionally having one or more halogen atoms, q is 0 or 1,and Q¹ and Q² represent an oxygen atom.

Embodiment 98

The compound described in Embodiment 90 wherein A¹ represents CH.

Embodiment 99

The compound described in Embodiment 98 wherein R² represents an ethylgroup, R³ represents a C1-C6 alkyl group optionally having one or moresubstituents selected from Group B, a C3-C7 cycloalkyl group optionallyhaving one or more substituents selected from Group E, a phenyl group, apyridyl group, a pyrimidinyl group, a pyrazolyl group, a triazolyl group{the phenyl group, the pyridyl group, the pyrimidinyl group, thepyrazolyl group, and the triazolyl group each independently mayoptionally have one or more substituents selected from Group J}, OR¹²,NR¹¹R¹², NR¹¹C(O)OR¹⁴, or a halogen atom, R^(4c) represents a hydrogenatom, R⁵ represents a C1-C6 alkyl group optionally having one or morehalogen atoms, q is 0 or 1, and Q¹ and Q² represent an oxygen atom.

Embodiment 100

A compound of the present invention wherein Het represents a grouprepresented by formula Het2 and A² and A⁴ represent a nitrogen atom.

Embodiment 101

The compound described in Embodiment 100 wherein A¹ represents anitrogen atom or CH.

Embodiment 102

The compound described in Embodiment 101 wherein R² represents an ethylgroup, R³ represents a C1-C6 alkyl group optionally having one or moresubstituents selected from Group B, a C3-C7 cycloalkyl group optionallyhaving one or more substituents selected from Group E, a phenyl group, apyridyl group, a pyrimidinyl group, a pyrazolyl group, a triazolyl group{the phenyl group, the pyridyl group, the pyrimidinyl group, thepyrazolyl group, and the triazolyl group each independently mayoptionally have one or more substituents selected from Group J}, OR¹²,NR¹¹R¹², NR¹¹C(O)OR¹⁴, or a halogen atom, R⁵ represents a C1-C6 alkylgroup optionally having one or more halogen atoms, q is 0 or 1, and Q¹and Q² represent an oxygen atom.

Embodiment 103

The compound described in Embodiment 100 wherein A¹ represents anitrogen atom.

Embodiment 104

The compound described in Embodiment 103 wherein R³ represents a C1-C6alkyl group optionally having one or more substituents selected fromGroup B, a C3-C7 cycloalkyl group optionally having one or moresubstituents selected from Group E, a phenyl group, a pyridyl group, apyrimidinyl group, a pyrazolyl group, a triazolyl group {the phenylgroup, the pyridyl group, the pyrimidinyl group, the pyrazolyl group,and the triazolyl group each independently may optionally have one ormore substituents selected from Group J}, OR¹², NR¹¹R¹², NR¹¹C(O) OR¹⁴,or a halogen atom.

Embodiment 105

The compound described in Embodiment 103 wherein R² represents a C1-C6alkyl group, q is 0 or 1, and Q¹ and Q² represent an oxygen atom.

Embodiment 106

The compound described in Embodiment 105 wherein R³ represents a C1-C6alkyl group optionally having one or more substituents selected fromGroup B, a C3-C7 cycloalkyl group optionally having one or moresubstituents selected from Group B, a phenyl group, a pyridyl group, apyrimidinyl group, a pyrazolyl group, a triazolyl group {the phenylgroup, the pyridyl group, the pyrimidinyl group, the pyrazolyl group,and the triazolyl group each independently may optionally have one ormore substituents selected from Group J}, OR¹², NR¹¹R¹², NR¹¹C(O)OR¹⁴,or a halogen atom, and R⁵ represents a C1-C6 alkyl group optionallyhaving one or more halogen atoms.

Embodiment 107

The compound described in Embodiment 103 wherein R² represents a C1-C6alkyl group, R³ represents a C1-C6 alkyl group, a C3-C7 cycloalkyl group{the C1-C6 alkyl group and the C3-C7 cycloalkyl group each independentlymay optionally have one or more substituents selected from the groupconsisting of a halogen atom and a cyano group}, phenyl group, a pyridylgroup {the phenyl group and the pyridyl group each independently mayoptionally have one or more substituents selected from Group G}, or ahalogen atom, R⁵ represents a C1-C6 alkyl group optionally having one ormore halogen atoms, q is 0 or 1, and Q¹ and Q² represent an oxygen atom.

Embodiment 108

The compound described in Embodiment 100 wherein A¹ represents CH.

Embodiment 109

The compound described in Embodiment 108 wherein R² represents an ethylgroup, R³ represents a C1-C6 alkyl group optionally having one or moresubstituents selected from Group B, a C3-C7 cycloalkyl group optionallyhaving one or more substituents selected from Group E, a phenyl group, apyridyl group, a pyrimidinyl group, a pyrazolyl group, a triazolyl group{the phenyl group, the pyridyl group, the pyrimidinyl group, thepyrazolyl group, and the triazolyl group each independently mayoptionally have one or more substituents selected from Group J}, OR¹²,NR¹¹R¹², NR¹¹C(O) OR¹⁴, or a halogen atom, R⁵ represents a C1-C6 alkylgroup optionally having one or more halogen atoms, q is 0 or 1, and Q¹and Q² represent an oxygen atom.

Embodiment 110

A compound of the present invention wherein Het represents a grouprepresented by formula Het1, A² represents CR^(4a), A³ representsCR^(4b), and when Het represent a group represented by Het2, A²represents CR^(4a) and A⁴ represents CR^(4c).

Embodiment 111

The compound described in Embodiment 110 wherein A¹ represents anitrogen atom or CH.

Embodiment 112

The compound described in Embodiment 111 wherein R² represents an ethylgroup, R³ represents a C1-C6 alkyl group optionally having one or moresubstituent selected from Group B, a C3-C7 cycloalkyl group optionallyhaving one or more substituents selected from Group E, a phenyl group, apyridyl group, a pyrimidinyl group, a pyrazolyl group, a triazolyl group{the phenyl group, the pyridyl group, the pyrimidinyl group, thepyrazolyl group, and the triazolyl group each independently mayoptionally have one or more substituents selected from Group J}, OR¹²,NR¹¹R¹², NR¹¹C(O)OR¹⁴, or a halogen atom, R^(4a), R^(4b) and R^(4c)represent a hydrogen atom, R⁵ represents a C1-C6 alkyl group optionallyhaving one or more halogen atoms, q is 0 or 1, and Q¹ and Q² representan oxygen atom.

Embodiment 113

The compound described in Embodiment 110 wherein A¹ represents anitrogen atom.

Embodiment 114

The compound described in Embodiment 113 wherein R³ representsa C1-C6alkyl group optionally having one or more substituents selected fromGroup B, a C3-C7 cycloalkyl group optionally having one or moresubstituents selected from Group E, a phenyl group, a pyridyl group, apyrimidinyl group, a pyrazolyl group, a triazolyl group {the phenylgroup, the pyridyl group, the pyrimidinyl group, the pyrazolyl group,and the triazolyl group each independently may optionally have one ormore substituents selected from Group J}, OR¹², NR¹¹R¹², NR¹¹C(O)OR¹⁴,or a halogen atom.

Embodiment 115

The compound described in Embodiment 113 wherein R² represents a C1-C6alkyl group, R^(4a), R^(4b) and R^(4c) represent a hydrogen atom or ahalogen atom, q is 0 or 1, and Q¹ and Q² represent an oxygen atom.

Embodiment 116

The compound described in Embodiment 115 wherein R³ represents a C1-C6alkyl group optionally having one or more substituents selected fromGroup B, a C3-C7 cycloalkyl group optionally having one or moresubstituents selected from Group E, a phenyl group, a pyridyl group, apyrimidinyl group, a pyrazolyl group, a triazolyl group {the phenylgroup, the pyridyl group, the pyrimidinyl group, the pyrazolyl group,and the triazolyl group each independently may optionally have one ormore substituents selected from Group J}, OR¹², NR¹¹R¹², NR¹¹C(O)OR¹⁴,or a halogen atom, and R⁵ represents a C1-C6 alkyl group optionallyhaving one or more halogen atoms.

Embodiment 117

The compound described in Embodiment 113 wherein R² represents a C1-C6alkyl group, R³ represents a C1-C6 alkyl group, a C3-C7 cycloalkyl group{the C1-C6 alkyl group and the C3-C7 cycloalkyl group each independentlymay optionally have one or more substituents selected from the groupconsisting of a halogen atom and a cyano group}, a phenyl group, apyridyl group {the phenyl group and the pyridyl group each independentlymay optionally have one or more substituents selected from Group G}, ora halogen atom, R^(4a), R^(4b), R^(4c) represent a hydrogen atom, R⁵represents a C1-C6 alkyl group optionally having one or more halogenatoms, q is 0 or 1, and Q¹ and Q² represent an oxygen atom.

Embodiment 118

The compound described in Embodiment 113 wherein R² represents an ethylgroup, R³, R^(4a), R^(4b) and R^(4c) represent a hydrogen atom, R⁵represents a C1-C6 alkyl group, q is 0, n is 2, and Q¹ and Q² representan oxygen atom.

Embodiment 119

The compound described in Embodiment 110 wherein A¹ represents CH.

Embodiment 120

The compound described in Embodiment 119 wherein R² represents an ethylgroup, R³ represents a C1-C6 alkyl group optionally having one or moresubstituents selected from Group B, a C3-C7 cycloalkyl group optionallyhaving one or more substituents selected from Group E, a phenyl group, apyridyl group, a pyrimidinyl group, a pyrazolyl group, a triazolyl group{the phenyl group, the pyridyl group, the pyrimidinyl group, thepyrazolyl group, and the triazolyl group each independently mayoptionally have one or more substituents selected from Group J}, OR¹²,NR¹¹R¹², NR¹¹C(O)OR¹⁴, or a halogen atom, R^(4a), R^(4b) and R^(4c)represent a hydrogen atom, R⁵ represents a C1-C6 alkyl group optionallyhaving one or more halogen atoms, q is 0 or 1, and Q¹ and Q² representan oxygen atom.

Embodiment 121

A compound of the present invention wherein A¹ represents a nitrogenatom or CH, R² represents an ethyl group, R³ represents a C1-C5 alkylgroup, a C3-C7 cycloalkyl group {the C1-C6 alkyl group and the C3-C7cycloalkyl group each independently may optionally have one or moresubstituents selected from the group consisting of a halogen atom and acyano group}, a phenyl group, a pyrazolyl group, a pyridyl group {thephenyl group, the pyrazolyl group, and the pyridyl group eachindependently may optionally have one or more substituents selected fromGroup G}, or a halogen atom, R^(4a), R^(4b) and R^(4c) represent ahydrogen atom, R⁵ represents a C1-C6 alkyl group or a C3-C6 cycloalkylgroup, q is 0 or 1, n is 2, and Q¹ and Q² represent an oxygen atom.

Embodiment 122

A compound of the present invention wherein A¹ represents a nitrogenatom or CH, R² represents an ethyl group, R³ represents a C1-C6 alkylgroup, a C3-C7 cycloalkyl group {the C1-C6 alkyl group and the C3-C7cycloalkyl group each independently may optionally have one or moresubstituents selected from the group consisting a halogen atom and acyano group}, a phenyl group, a pyridyl group {the phenyl group, thepyrimidinyl group, and the pyridyl group each independently mayoptionally have one or more substituents selected from Group G}, or ahalogen atom, R^(4a), R^(4b) and R^(4c) represent a hydrogen atom, R⁵represents a C1-C6 alkyl group, q is 0 or 1, n is 2, and Q² and Q²represent an oxygen atom.

Embodiment 123

A compound of the present invention wherein T represents a C1-C5 chainhydrocarbon group having one or more halogen atoms, OR¹, S(O)_(v)R¹,OS(O)₂R¹, CH₂OR¹, NR¹R²⁹, C(O)R¹, C(O)NR¹R²⁹, NR²⁹C(O)R¹, N═CR¹R³⁰, agroup represented by formula T-1, a group represented by formula T-2, agroup represented by formula T-3, a group represented by formula T-4, agroup represented by formula T-5, a group represented by formula T-6, agroup represented by formula T-7, a group represented by formula T-8, agroup represented by formula T-9, a group represented by formula T-10, agroup represented by formula T-11, or a group represented by formulaT-12, and R¹, R^(1x), R^(1y) and R^(1ay) are identical to or differentfrom each other and each represents independently a C1-C5 chainhydrocarbon group having one more halogen atoms.

Embodiment 124

A compound of the present invention wherein T represents a C1-C5 alkylgroup having three or more fluorine atoms, OR¹, S(O)_(v)R¹, OS(O)₂R¹,CH₂OR¹, NR¹R²⁹, C(O)R¹, C(O)NR¹R²⁹, NR²⁹C(O)R¹, N═CR¹R³⁰, a grouprepresented by formula T-1, a group represented by formula T-2, a grouprepresented by formula T-3, a group represented by formula T-4, a grouprepresented by formula T-5, a group represented by formula T-6, a grouprepresented by formula T-7, a group represented by formula T-8, a grouprepresented by formula T-9, a group represented by formula T-10, a grouprepresented by formula T-11, or a group represented by formula T-12, andR¹, R^(1x), R^(1y) and R^(1ay) are identical to or different from eachother and each represents independently a C1-C5 alkyl group having threeor more fluorine atoms.

Embodiment 125

A compound of the present invention wherein T represents a C1-C5 chainhydrocarbon group having one or more halogen atoms, OR¹, S(O)_(v)R¹,OS(O)₂R¹, NR¹R²⁹, a group represented by formula T-1, a grouprepresented by formula T-2, a group represented by formula T-3, a grouprepresented by formula T-4, or a group represented by formula T-8, andR¹, R^(1x) and R^(1y) are identical to or different from each other andeach represents independently a C1-C5 chain hydrocarbon group having oneor more halogen atoms.

Embodiment 126

A compound of the present invention wherein T represents a C1-C5 alkylgroup having three or more fluorine atoms, OR¹, S(O)_(v)R¹, OS(O)₂R¹,NR¹R²⁹, a group represented by formula T-1, a group represented byformula T-2, a group represented by formula T-3, a group represented byformula T-4, or a group represented by formula T-8, and R¹, R^(1x) andR^(1y) are identical to or different from each other and each representsindependently a C1-C5 alkyl group having three or more fluorine atoms.

Embodiment 127

A compound of the present invention wherein T represents a C1-C5 chainhydrocarbon group having one or more halogen atoms, OR¹, S(O)_(v)R¹,OS(O)₂R¹, NR¹R²⁹, and R¹ represents a C1-C5 chain hydrocarbon grouphaving one more halogen atoms.

Embodiment 128

A compound of the present invention wherein T represents a C1-C5 alkylgroup having three or more fluorine atoms, OR¹, S(O)_(v)R¹, OS(O)₂R¹,NR¹R²⁹, and R¹ represents a C1-C5 alkyl group having three or morefluorine atoms.

Embodiment 129

A compound of the present invention wherein T represents OR¹.

Embodiment 130

The compound described in Embodiment 129 wherein R¹ represents a C1-C5chain hydrocarbon group having one or more halogen atoms.

Embodiment 131

The compound described in Embodiment 129 wherein R¹ represents a C1-C5alkyl group having three or more fluorine atoms.

Embodiment 132

A compound of the present invention wherein T represents a grouprepresented by formula T-1, a group represented by formula T-2, a grouprepresented by formula T-3, a group represented by formula T-4, or agroup represented by formula T-8.

Embodiment 133

The compound described in Embodiment 132 wherein R^(1x) and R^(1y) areidentical to or different from each other and each representsindependently a C1-C5 chain hydrocarbon group having one or more halogenatoms.

Embodiment 134

The compound described in Embodiment 132 wherein R^(1x) and R^(1y) areidentical to or different from each other and each representsindependently a C1-C5 alkyl group having three or more fluorine atoms.

Embodiment 135

The compound described in anyone of Embodiments 1 to 121 or 122 whereinT represents a C1-C5 chain hydrocarbon group having one or more halogenatoms, OR¹, S(O)_(v)R¹, OS(O)₂R¹, CH₂OR¹, NR¹R²⁹, C(O)R¹, C(O)NR¹R²⁹,NR²⁹C(O)R¹, N═CR¹R³⁰, a group represented by formula T-1, a grouprepresented by formula T-2, a group represented by formula T-3, a grouprepresented by formula T-4, a group represented by formula T-5, a grouprepresented by formula T-6, a group represented by formula T-7, a grouprepresented by formula T-8, a group represented by formula T-9, a grouprepresented by formula T-10, a group represented by formula T-11, or agroup represented by formula T-12, and R¹, R^(1x), R^(1y) and R^(1ay)are identical to or different from each other and each representsindependently a C1-C5 chain hydrocarbon group having one or more halogenatoms.

Embodiment 136

The compound described in Embodiments 1 to 121 or 122 wherein Trepresents a C1-C5 alkyl group having three or more fluorine atoms, OR¹,S(O)_(v)R¹, OS(O)₂R¹, CH₂OR¹, NR¹R²⁹, C(O)R¹, C(O)NR¹R²⁹, NR²⁹C(O)R¹,N═CR¹R³⁰, a group represented by formula T-1, a group represented byformula T-2, a group represented by formula T-3, a group represented byformula T-4, a group represented by formula T-5, a group represented byformula T-6, a group represented by formula T-7, a group represented byformula T-8, a group represented by formula T-9, a group represented byformula T-10, a group represented by formula T-11, or a grouprepresented by formula T-12, and R¹, R^(1x), R^(1y) and R^(1ay) areidentical to or different from each other and each representsindependently a C1-C5 alkyl group having three or more fluorine atoms.

Embodiment 137

The compound described in anyone of Embodiments 1 to 121 or 122 whereinT represents a C1-C5 chain hydrocarbon group having one or more halogenatoms, OR¹, S(O)_(v)R¹, OS(O)₂R¹, NR¹R²⁹, a group represented by formulaT-1, a group represented by formula T-2, a group represented by formulaT-3, a group represented by formula T-4, or a group represented byformula T-8, and R¹, R^(1x), and R^(1y) are identical to or differentfrom each other and each represents independently a C1-C5 chainhydrocarbon group having one or more halogen atoms.

Embodiment 138

The compound described in anyone of Embodiments 1 to 121 or 122 whereinT represents a C1-C5 alkyl group having three or more fluorine atoms,OR¹, S(O)_(v)R¹, OS(O)₂R¹, NR¹R²⁹, a group represented by formula T-1, agroup represented by formula T-2, a group represented by formula T-3, agroup represented by formula T-4, or a group represented by formula T-8,and R¹, R^(1x), and R^(1y) are identical to or different from each otherand each represents independently a C1-C5 alkyl group having three ormore fluorine atoms.

Embodiment 139

The compound described in anyone or more Embodiments 1 to 121 or 122wherein T represents a C1-C5 chain hydrocarbon group having one or morehalogen atoms, OR¹, S(O)_(v)R¹, OS(O)₂R¹, NR¹R²⁹, anal R¹ represents aC1-C5 chain hydrocarbon group having one or more halogen atoms.

Embodiment 140

The compound described in anyone of Embodiments 1 to 121 or 122 whereinT represents a C1-C5 alkyl group having three or more fluorine atoms,OR¹, S(O)_(v)R¹, OS(O)₂R¹, or NR¹R²⁹, and R¹ represents a C1-C5 alkylgroup having three or more fluorine atoms.

Embodiment 141

The compound described in anyone of Embodiments 1 to 121 or 122 whereinT represents OR¹.

Embodiment 142

The compound described in anyone of Embodiments 1 to 121 or 122 whereinT represents OR¹, and R¹ represents a C1-C5 chain hydrocarbon grouphaving one or more halogen atoms.

Embodiment 143

The compound described in anyone of Embodiments 1 to 121 or 122 whereinT represents OR¹⁰, and R¹ represents a C1-C5 alkyl group having three ormore fluorine atoms.

Embodiment 144

The compound described in anyone of Embodiments 1 to 121 or 122 whereinT represents a group represented by formula T-1, a group represented byformula T-2, a group represented by formula T-3, a group represented byformula T-4, or a group represented by formula T-8.

Embodiment 145

The compound described in anyone of Embodiments 1 to 121 or 122 whereinT represents a group represented by formula T-1, a group represented byformula T-2, a group represented by formula T-3, a group represented byformula T-4, or a group represented by formula T-8, and R^(1x) andR^(1y) are identical to or different from each other and each representsindependently a C1-C5 chain hydrocarbon group having one or more halogenatoms.

Embodiment 146

The compound described in anyone of Embodiments 1 to 121 or 122 whereinT represents a group represented by formula T-1, a group represented byformula T-2, a group represented by formula T-3, a group represented byformula T-4, or a up represented by formula T-8, and R^(1x) and R^(1y)are identical to or different from each other and each representindependently a C1-C5 alkyl group having three or more fluorine atoms.

Embodiment 147

The compound described in Embodiments 1 to 121 or 122 wherein Trepresents OR¹, a group represented by formula T-1, a group representedby formula T-2, or a group represented by formula T-8, R¹, R^(1x) andR^(1y) are identical to or different from each other and each representsindependently a C1-C5 alkyl group having one or more fluorine atoms, X¹represents CR^(1a), X² represents CR^(1b), X³ represents CR^(1c) and X⁵represents CR^(1e).

Examples of the embodiment of the compound Z of the present inventioninclude the following compounds.

Embodiment 148

A compound Z of the present invention wherein R² represents an ethylgroup, R³ represents a C1-C6 alkyl group optionally having one or moresubstituents selected from Group B, a C3-C7 cycloalkyl group optionallyhaving one or more substituents selected from Group E, a phenyl group, apyridyl group, a pyrimidinyl group, pyrazolyl group, a triazolyl group{the phenyl group, the pyridyl group, the pyrimidinyl group, thepyrazolyl group, and the triazolyl group each independently mayoptionally have one or more substituents selected from Group J}, OR¹²,NR¹¹R¹², NR¹¹C(O)OR¹⁴, or a halogen atom, R^(4a), R^(4b) and R^(4c)represent a hydrogen atom, R⁵ represents a C1-C6 alkyl group optionallyhaving one or more halogen atoms, q is 0 or 1, n is 2, and Q¹ and Q²represent an oxygen atom.

Embodiment 149

The compound described in Embodiment 148 wherein A¹ represents anitrogen atom, T represents a C1-C5 alkyl group having one or moresubstituents selected from the group consisting of a cyano group and ahalogen atom, OR¹, S(O)_(v)R¹, OS(O)₂R¹, NR¹R²⁹, a group represented byformula T-1, a group represented by formula T-2, a group represented byformula T-3, a group represented by formula T-4, or a group representedby formula T-8, and R¹, R^(1x) and R^(1y) are identical to or differentfrom each other and each represents independently a C1-C5 alkyl groupoptionally having one or more substituents selected from the groupconsisting of a cyano group and a halogen atom.

Embodiment 150

The compound described in Embodiment 148 wherein A¹ represents anitrogen atom or CH, T represents a C1-C5 alkyl group having one or moresubstituents selected from the group consisting of a cyano group and ahalogen atom, OR¹, S(O)_(v)R¹, OS(O)₂R¹, or NR¹R²⁹, and R¹ represent aC1-C5 alkyl group having one or more substituents selected from thegroup consisting of a cyano group and a halogen atom.

Embodiment 151

The compound described in Embodiment 148 wherein A¹ represents anitrogen atom, T represents a group represented by formula T-1, a grouprepresented by formula T-2, a group represented by formula T-3, a grouprepresented by formula T-4, or a group represented by formula T-8, andR^(1x) and R^(1y) are identical to or different from each other and eachrepresents independently a C1-C5 alkyl group optionally having one ormore substituents selected from the group consisting of a cyano groupand a halogen atom.

Embodiment 152

The compound described in Embodiment 148 wherein A¹ represents anitrogen atom, and T represents a C1-C5 alkoxy group having one or moresubstituents selected from the group consisting of a cyano group and ahalogen atom.

Embodiment 153

The compound described in Embodiment 148 wherein R⁵ represents a C1-C6alkyl group optionally having one or more halogen atoms.

Embodiment 154

The compound described in Embodiment 153 wherein A¹ represents anitrogen atom or CH, T represents a C1-C5 alkyl group having one or moresubstituents selected from the group consisting of a cyano group and ahalogen atom, OR¹, S(O)_(v)R¹, OS(O)₂R¹, NR¹R²⁹, a group represented byformula T-1, a group represented by formula T-2, a group represented byformula T-3, a group represented by formula T-4, or a group representedby formula T-8, and R¹, R^(1x) and R^(1y) are identical to or differentfrom each other and each represents independently a C1-C5 alkyl groupoptionally having one or more substituents selected from the groupconsisting of a cyano group and a halogen atom.

Embodiment 155

The compound described in Embodiment 154 wherein A¹ represents anitrogen atom.

Embodiment 156

The compound described in Embodiment 153 wherein A¹ represents anitrogen atom or CH, T represents a C1-C5 alkyl group having one or moresubstituents selected from the group consisting of a cyano group and ahalogen atom, OR¹, S(O)_(v)R¹, OS(O)₂R¹, or NR¹R²⁹, and R¹ representsC1-C5 alkyl group optionally having one or more substituents selectedfrom the group consisting of a cyano group and a halogen atom.

Embodiment 157

The compound described in Embodiment 156 wherein A¹ represents anitrogen atom.

Embodiment 158

The compound described in Embodiment 153 wherein A¹ represents anitrogen atom or CH, T represents a group represented by formula T-1, agroup represented by formula T-2, a group represented by formula T-3, agroup represented by formula T-4, or a group represented by formula T-8,and R^(1x) and R^(1y) are identical to or different from each other andeach represents independently a C1-C5 alkyl group optionally having oneor more substituents selected from the group consisting of a cyano groupand a halogen atom.

Embodiment 159

The compound described in Embodiment 158 wherein A¹ represents anitrogen atom.

Embodiment 160

The compound described in Embodiment 153 wherein A¹ represents anitrogen atom or CH, and T represents a C1-C5 alkoxy group having one ormore substituents selected from the group consisting of a cyano groupand a halogen atom.

Embodiment 161

The compound described in Embodiment 160 wherein A¹ represents anitrogen atom.

Examples of the embodiment of the intermediate compound D include thefollowing compounds.

Embodiment 162

An intermediate compound D wherein R² represents a C1-C6 alkyl groupoptionally having one or more halogen atoms, n is 2, R^(w) representsC1-C6 chain hydrocarbon group optionally having one or more halogenatoms, T^(W) represents a halogen atom, a C1-C6 alkylsulfanyl group, aC1-C6 alkylsulfinyl group, a C1-C6 alkylsulfonyl group, and R^(4a),R^(4b) and R^(4c) each represents a hydrogen atom.

Embodiment 163

The compound described in Embodiment 162 wherein A² represents CH, A³represents a nitrogen atom or CH, and A⁴ represents a nitrogen atom orCH.

Embodiment 164

The compound described in Embodiment 162 wherein A² represents CH, A³represents CH, and A⁴ represents a nitrogen atom.

Embodiment 165

The compound described in Embodiment 162 wherein A² represents CH, A³represents a nitrogen atom, and A⁴ represents CH.

Embodiment 166

The compound described in Embodiments 162 to 165 wherein R² representsan ethyl group, R^(w) represents a C1-C3 alkyl group, and T^(W)represents a halogen atom or a C1-C3 alkylsulfanyl group.

Embodiment 167

The compound described in Embodiments 162 to 165 wherein R² representsan ethyl group, R^(w) represents a C1-C3 alkyl group, and T^(W)represents a halogen atom.

Examples of the embodiment of the intermediate compound E include thefollowing compounds.

Embodiment 168

An intermediate compound E wherein R² represents a C1-C6 alkyl groupoptionally having one or more halogen atoms, n is 0 or 2, R^(w)represents a C1-C6 chain hydrocarbon group optionally having one or morehalogen atoms, a benzyl group optionally having one or more substituentsselected from Group A, or a hydrogen atom, T^(W2) represents a halogenatom, a C1-C6 alkylsulfanyl group, a C1-C6 alkylsulfinyl group, or aC1-C6 alkylsulfonyl group, R³ represents a C1-C6 alkyl group optionallyhaving one or more substituents selected from Group B, or a hydrogenatom, and R^(4a), R^(4b) and R^(4c) each represents a hydrogen atom.

Embodiment 169

The compound described in Embodiment 168 wherein A² represents CH, A³represents a nitrogen atom or CH, and A⁴ represents a nitrogen atom orCH.

Embodiment 170

The compound described in Embodiment 168 wherein A² represents CH, A³represents CH, and A⁴ represents a nitrogen atom.

Embodiment 171

The compound described in Embodiment 168 wherein A² represents CH, A³represents a nitrogen atom, and A⁴ represents CH.

Embodiment 172

The compound described in Embodiments 168 to 171 wherein R² representsan ethyl group, R^(w) represents a C1-C3 alkyl group or a benzyl group,T^(W2) represents a halogen atom or a C1-C3 alkylsulfanyl group, and qis 0 or 1.

Embodiment 173

The compound described in Embodiments 168 to 171 wherein R² representsan ethyl group, R^(w) represents a C1-C3 alkyl group or a benzyl group,T^(W2) represents a halogen atom, and q is 0 or 1.

Examples of the embodiment of the intermediate compound F include thefollowing compounds.

Embodiment 174

An intermediate compound F wherein A¹ represents a nitrogen atom or CH,R² represents a C1-C6 alkyl group optionally having one or more halogenatoms, n is 0 or 2, X^(L) represents a halogen atom, a hydroxy group, aC1-C6 alkylsulfanyl group, a C1-C6 alkylsulfinyl group, a C1-C6alkylsulfonyl group, R³ represents a C1-C6 alkyl group optionally havingone or more substituents selected from Group B, a halogen atom orNR¹¹R¹¹, and R^(4a), R^(4b) and R^(4c) each represents a hydrogen atom.

Embodiment 175

The compound described in Embodiment 175 wherein A² represents CH, A³represents a nitrogen atom or CH, and A⁴ represents a nitrogen atom orCH.

Embodiment 176

The compound described in Embodiment 174 wherein A² represents CH, A³represents CH, and A⁴ represents a nitrogen atom.

Embodiment 177

The compound described in Embodiment 174 wherein A² represents CH, A³represents a nitrogen atom, and A⁴ represents CH.

Embodiment 178

The compound described in Embodiments 174 to 177 wherein R² representsan ethyl group, X^(L) represents a halogen atom, a C1-C3 alkylsulfanylgroup or a C1-C3 alkylsulfonyl group, and q is 0 or 1.

Embodiment 179

The compound described in Embodiments 174 to 177 wherein Q represents anoxygen atom.

Embodiment 180

The compound described in Embodiments 174 to 177 wherein R⁵ represents aC1-C6 chain hydrocarbon group {the C1-C6 chain hydrocarbon group haveone or more substituents selected from the group consisting of a halogenatom, a cyclopropyl group, a phenyl group, and a cyclothiazolyl group}or a C3-C6 cycloalkyl group.

Next, a process for preparing the compound Z of the present invention isexplained.

Process 1

A compound represented by formula (Ib) (hereinafter, referred to asCompound (Ib)) or a compound represented by formula (Ic) (hereinafter,referred to as Compound (Ic)) may be prepared by oxidizing a compoundrepresented by formula (Ia) (hereinafter, referred to as Compound (Ia)).

[wherein the symbols are the same as defined above]

First, a process for preparing the Compound (Ib) from the Compound (Ia)is described.

The reaction is usually carried out in a solvent.

Examples of the solvent to be used in the reaction include halogenatedhydrocarbons such as dichloromethane and chloroform (hereinafter,collectively referred to as halogenated hydrocarbons); nitriles such asacetonitrile (hereinafter collectively referred to nitriles); alcoholssuch as methanol and ethanol (hereinafter, collectively referred to asalcohols); acetic acid; water; and mixed solvents thereof.

Examples of the oxidizing agent to be used in the reaction includesodium periodate, m-chloroperoxybenzoic acid (hereinafter, referred toas mCPBA) and hydrogen peroxide. When hydrogen peroxide is used as anoxidizing agent, sodium carbonate or a catalyst may be added as needed.

Examples of the catalyst to be used in the reaction include tungsticacid, and sodium tungstate.

In the reaction, the oxidizing agent is used usually within a range of 1to 1.2 molar ratio(s), the base is used usually within a range of 0.01to 1 molar ratio(s), and the catalyst is used usually within a range of0.01 to 0.5 molar ratios, as opposed to 1 mole of the compound (Ia).

The reaction temperature of the reaction is usually within a range of−20 to 80° C. The reaction period of the reaction is usually within arange of 0.1 to 12 hours.

When the reaction is completed, water is added to reaction mixtures, andthe reaction mixtures are extracted with organic solvent(s), and ifnecessary, the organic layers are washed with an aqueous solution of areducing agent (such as sodium sulfite, and sodium thiosulfate) and anaqueous solution of a base (such as sodium hydrogen carbonate). Theresulting organic layers are worked up (for example, drying andconcentration) to give the compound (Ib).

Next, a process for preparing the compound (IC) from the compound (Ib)is described.

The reaction is usually carried out in a solvent. Examples of thesolvent to be used in the reaction include halogenated hydrocarbons,nitriles, alcohols, acetic acid, water, and mixed solvents thereof.

Examples of the oxidizing agent to be used in the reaction include mCPBAand peroxide hydrogen. When peroxide hydrogen is used as an oxidizingagent, a base or a catalyst may be added as needed.

Examples of the base to be used in the reaction include sodiumcarbonate.

Examples of the catalyst to be used in the reaction include sodiumtungstate.

In the reaction, the oxidizing agent is used usually within a range of 1to 2 molar ratio(s), the base is used usually within a range of 0.01 to1 molar ratio(s), and the catalyst is used usually within a range of0.01 to 0.5 molar ratios, as opposed to 1 mole of the compound (Ib).

The reaction temperature of the reaction is usually within a range of−20 to 120° C. The reaction period of the reaction is usually within arange of 0.1 to 12 hours.

When the reaction is completed, water is added to reaction mixtures, andthe reaction mixtures are extracted with organic solvent(s), and ifnecessary, the organic layers are washed with an aqueous solution of areducing agent (such as sodium sulfite, and sodium thiosulfate) and anaqueous solution of a base (such as sodium hydrogen carbonate). Theresulting organic layers are worked up (for example, drying andconcentration) to give the compound (Ic).

Also, the compound (Ic) may be prepared by reacting the compound (Ia)with an oxidizing agent in one step (one pot).

The reaction may be carried out by using the oxidizing agent in a ratioof usually 2 to 5 molar ratios as opposed to 1 mole of the compound (Ia)according to the method for preparing the compound (Ic) from thecompound (Ib).

Process 2

A compound represented by formula (Id-2) (hereinafter, referred to asCompound (Id-2)) may be prepared by reacting a compound represented byformula (M-2) (hereinafter, referred to as Compound (M-2)) and acompound represented by formula (R-1) (hereinafter, referred to asCompound (R-1)) in the presence of a base.

[wherein X^(b) represents a chlorine atom or a bromine atom, T¹represents OR¹, NR¹R²⁹ a group represented by formula T-5, a grouprepresented by formula T-6, a group represented by formula T-7, or agroup represented by formula T-8, and the other symbols are the same asdefined above.]

The reaction is usually carried out in the presence of a solvent.Examples of the solvents to be used in the reaction include ethers suchas tetrahydrofuran (hereinafter, sometimes referred to as THF) andmethyl tert-butyl ether (hereinafter, referred to as MTBE) (hereinafter,collectively referred to as ethers); aromatic hydrocarbons such astoluene and xylene (hereinafter, collectively referred to as aromatichydrocarbons); nitriles; N-methyl pyrrolidone (hereinafter, referred toas NMP); and aprotic polar solvents such as dimethylformamide(hereinafter, referred to as DMF) and dimethyl sulfoxide (hereinafter,referred to DMSO) (hereinafter, collectively referred to as polaraprotic solvent); and mixed solvents thereof.

Examples of the base to be used in the reaction include alkali metalcarbonates (such as potassium carbonate) (hereinafter, collectivelyreferred to as alkali metal carbonates); and alkali metal hydrides suchas sodium hydride (hereinafter, collectively referred to as alkali metalhydrides).

In the reaction, the compound (R-1) is used usually within a range of 1to 2 molar ratio(s), and the base is used usually within a range of 1 to10 molar ratio(s), as opposed to 1 mole of the compound (M-2)

The reaction temperature of the reaction is usually within a range of−20 to 150° C. The reaction period the reaction is usually within arange of 0.5 to 24 hours.

When the reaction is completed, water is added to reaction mixtures, andthe reaction mixtures are extracted with organic solvent(s), and theorganic layers are worked up (for example, drying and concentration) togive the compound (Id-2).

Process 3

A compound represented by formula (Id-4) may be Prepared by reacting acompound represented by formula (M-3) (hereinafter, referred to asCompound (M-3)) with the compound (R-1) in the presence of a base.

[wherein the symbols are the same as defined above]

The reaction may be carried out according to the method described inProcess 2.

Process 4

A compound represented by formula (Ie-2) (hereinafter, referred toCompound (Ie-2)) may be prepared by reacting the compound (M-2) with acompound represented by formula (R-2) (hereinafter, referred to Compound(R-2)) in the presence of a metal catalyst.

[wherein T² represents a group represented by formula T-1, a grouprepresented by formula T-2, group represented by formula T-3, a grouprepresented by formula T-4, a group represented by formula T-9, a grouprepresented by formula T-10, a group represented by formula T-11, or agroup represented by formula T-12, M represents9-borabiclo[3,3,1]nonan-9-yl, a borono group, a4,4,5,5,-tetramethyl-1,3,2-dioxaborolan-2-yl, a tributylstannyl group,ZnCl, MgCl, or MgBr; and the other symbols are the same as definedabove]

The reaction is usually carried out in the presence of a solvent.Examples of the solvent to be used in the reaction include ethers,aromatic hydrocarbons, aprotic polar solvents, water, and mixed solventsthereof.

Examples of the metal catalyst to be used in the reaction includepalladium catalysts such as tetrakis(triphenylphosphine)palladium(0),1,1′-bis(diphenylphosphino)ferrocene palladium(II) dichloride,tris(dibenzylideneacetone)dipalladium(0), and palladium(II) acetate;nickel catalysts such as bis(cyclooctadiene)nickel(0) and nickel (II)chloride; and copper catalyst such as copper (I) iodide and copper(I)chloride.

A ligand, a base and/or an inorganic halogenated compound may be addedto the reaction as needed.

Examples of the ligand to be used in the reaction includetriphenylphosphine, Xantphos,2,2′-bis(diphenylphoshino)-1,1′-binaphthyl,1,1′-bis(diphenylphoshino)ferrocene,2-dicyclohexylphosphino-2′,4′,6′-triisopropylbiphenyl,2-dicyclohexylphosphino-2′,6′-dimethoxybiphenyl,1,2-bis(diphenylphosphino)ethane, 2,2′-bipyridine, 2-aminoethanol,8-hydroxyquinoline, and 1,10-phenanthroline.

Examples of the base to be used in the reaction include alkali metalhydrides; alkali metal carbonates; and organic bases such astriethylamine, diisopropylethylamine, pyridine, and4-(dimethylanino)pyridine.

Examples of the inorganic halogenated compounds include alkali metalfluorides such as potassium fluoride, and sodium fluoride; and alkalimetal chlorides such as lithium chloride, and sodium chloride.

In the reaction, the compound (R-2) is usually used within a range of 1to 10 molar ratio(s), the metal catalyst is usually used within a rangeof 0.01 to 0.5 molar ratios, the ligand is usually used within a rangeof 0.01 to 1 molar ratio(s), the base is usually used within a range of0.1 to 1 molar ratio(s), and the inorganic halogenated compound isusually used within a range of 0.1 to 5 molar ratios, as opposed to 1mole of the compound (M-2).

The reaction temperature is usually within a range of −20 to 200° C. Thereaction period of the reaction is usually within a range of 0.1 to 24hours.

When the reaction is completed, water is added to the reaction mixtures,and the reaction mixtures are extracted with organic solvent(s), and theorganic solvents are worked up (for example, drying and concentration)to give the compound (Ie-2).

The compound (R-2) is a commercially available compound, or can beprepared by using a known method.

Process 5

A compound represented by formula (Ie-4) may be prepared by reacting thecompound (M-3) with the compound (R-2) in the presence of a metalcatalyst.

[wherein the symbols are the same as defined above.]

The reaction may be carried out according to the method described inProcess 4.

Process 6

A compound represented by formula (If-2) may be prepared by reacting acompound represented by formula (M-4) (hereinafter, referred to asCompound (M-4)) with a compound represented by formula (R-3)(hereinafter, referred to as Compound (R-3)) in the presence of a base.

[wherein X^(c) represents a chlorine atom, a bromine atom or an iodineatom, T³ represents a C1-C10 chain hydrocarbon group having one or morehalogen atoms, a (C1-C5 alkoxy)C2-C5 alkyl group having one or morehalogen atoms, a (C1-C5 alkylsulfanyl)C2-C5 alkyl group having one ormore halogen atoms, a (C1-C5 alkylsulfinyl)C2-C5 alkyl group having oneor more halogen atoms, a (C1-C5 alkylsulfonyl)C2-C5 alkyl group havingone or more halogen atoms, a (C3-C7 cycloalkyl)C1-C3 alkyl group havingone or more substituents selected from Group G, a C3-C7 cycloalkyl grouphaving one or more substituents selected from Group G, or S(O)₂R¹, andthe other symbols are the same as defined above.]

The reaction may be carried out by using the compound (M-4) in place ofthe compound (R-1), and the compound (R-3) in place of the compound(M-2) according to the method described in Process 2.

The compound (R-3) is a commercially available compound, or can beprepared by using a known method.

Process 7

A compound represented by formula (If-4) may be prepared by reacting acompound represented by formula (M-5) (hereinafter, referred to Compound(M-5)) with the compound (R-3) in the presence of a base.

[wherein the symbols are the same as defined above.]

The reaction may be carried out according to the method described inProcess 6.

Process 8

A compound represented by formula (Ig-2) (hereinafter, referred to asCompound (Ig-2)) may be prepared by reacting the compound (M-2) with acompound represented by formula (R-4) (hereinafter, referred to asCompound (R-4)) in the presence of a copper.

[wherein, T⁴ represents a C1-C10 chain hydrocarbon group having one ormore halogen atoms, a (C1-C5 alkoxy)C2-C5 alkyl group having one or morehalogen atoms, (C1-C5 alkylsulfanyl)C2-C5 alkyl group having one or morehalogen atoms, a (C1-C5 alkylsulfinyl)C2-C5 alkyl group having one ormore halogen atoms, a (C1-C5 alkylsulfonyl)C2-C5 alkyl group having oneor more halogen atoms, a (C3-C7 cycloalkyl)C1-C3 alkyl group having oneor more substituents selected from Group G, or a C3-C7 cycloalkyl grouphaving one or more substituents selected from Group G, and the othersymbols are the same as defined above.]

The compound (R-4) is a commercially available compound, or can beprepared by using a known method.

The reaction is usually carried out in the presence of a solvent.Examples of the solvent to be used in the reaction include aromatichydrocarbons, aprotic polar solvents, and mixed solvents thereof.

In the reaction, the compound (R-4) is usually used within a range of 1to 10 molar ratio (s), and the copper is usually used within a range of1 to 10 molar ratio(s), as opposed to 1 mole of the compound (M-2).

The reaction temperature is usually within a range of 40 to 200° C. Thereaction period of the reaction is usually within a range of 0.1 to 24hours.

When the reaction is completed, water is added to the reaction mixtures,and the reaction mixtures are extracted with organic solvent(s), and theorganic solvents are worked up (for example, drying and concentration)to give the compound (Ig-2).

Process 9

The compound represented by formula (Ig-4) may be prepared by reactingthe compound (M-3) with the compound (R-4) in the presence of a copper.

[wherein the symbols are the same as defined above.]

The reaction may be carried out according to the method described inProcess 8.

Process 10

A compound represented by formula (Ih-2) (hereinafter, referred toCompound (Ih-2)) may be prepared by reacting the compound (M-2) with acompound represented by formula (R-5) (hereinafter, referred to asCompound (R-5)) in the presence of a base.

[wherein, R⁴⁰ represents a methoxy group, an ethoxy group, a phenoxygroup, or N(CH₃)CH₃, and the other symbols are the same as definedabove.]

The compound (R-5) is a commercially available compound, or can beprepared by using a known method.

The reaction is usually carried out in the presence of a solvent.Examples of the solvent to be used in the reaction include ethers, andaromatic hydrocarbons.

Examples of the base to be used in the reaction include butyl lithium,lithium diisopropylamide, lithium tetramethylpiperidide, lithiumbis(trimethylsilyl)amide and the like.

In the reaction, the compound (R-5) is usually used within a range of 1to 10 molar ratio(s), and the base is usually used within a range of 1.0to 2.0 molar ratio(s), as opposed to 1 mole of the compound (M-2).

The reaction temperature is usually within a range of −100 to 60° C. Thereaction period of the reaction is usually within a range of 0.1 to 24hours.

When the reaction is completed, water is added to the reaction mixtures,and the reaction mixtures are extracted with organic solvent(s), and theorganic solvents are worked up (for example, drying and concentration)to give the compound (Ih-2).

Process 11

A compound represented by formula (Ih-4) may be prepared by reacting thecompound (M-3) with the compound (R-5) in the presence of a base.

[wherein the symbols are the same as defined above.]

The reaction may be carried out according to the method described inProcess 10.

Process 12

A compound represented by formula (Ii-2) (hereinafter, referred to asCompound (Ii-2)) may be prepared by reacting compound represented byformula (M-6) (hereinafter, referred to as Compound (M-6)) with acompound represented by formula (R-6) (hereinafter, referred to asCompound (R-6)) in the presence of a condensing agent.

[wherein the symbols are the same as defined above.]

The compound (R-6) is a commercially available compound, or can beprepared by using a known method.

The reaction is usually carried out in a solvent. Examples of thesolvent to be used in the reaction include ethers, halogenatedhydrocarbons, aromatic hydrocarbons, aprotic polar solvents, and mixedsolvents thereof.

Examples of the condensing agent to be used in the reaction include1-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride and thelike.

A base may be added to the reaction as needed, and examples of the basesinclude organic bases.

In the reaction, the compound (R-6) is used usually within a range of 1to 10 molar ratio(s), the condensing agent is used usually within arange of 1 to 5 molar ration(s), and the base is used usually within arange of 0.1 to 10 molar ratios, as opposed to 1 mole of the compound(M-6).

The reaction temperature of the reaction is usually within a range of−20 to 120° C. The reaction period of the reaction is usually within arange of 0.1 to 24 hours.

When the reaction is completed, water is added to the reaction mixtures,and the reaction mixtures are extracted with organic solvent(s), and theorganic solvents are worked up (for example, drying and concentration)to give the compound (Ii-2).

Process 13

A compound represented by formula (Ii-4) may be prepared by reacting acompound represented by formula (M-7) (hereinafter, referred to asCompound (M-7)) with the compound (R-6) in the presence a condensingagent.

[wherein the symbols are the same as defined above.]

The reaction may be carried out according to the method described inProcess 12.

Process 14

A compound represented by formula (Ij-2) (hereinafter, referred to asCompound (Ij-2)) may be prepared by reacting a compound represented byformula (M-8) (hereinafter, referred to as Compound (M-8)) with acompound represented by formula (R-7) (hereinafter, referred to asCompound (R-7)) in the presence of a base.

[wherein the symbols are the same as defined above.]

The compound (R-7) is a commercially available compound, or can beprepared by a known method.

The reaction is usually carried out in a solvent. Examples of thesolvent to be used in the reaction include ethers, aromatichydrocarbons, aprotic polar solvents, and mixed solvents thereof.

Examples of the base to be used in the reaction include organic bases,alkali metal hydrides, and alkali metal carbonates.

In the reaction, the compound (R-7) is used usually within a range of 1to 10 molar ratio(s), and the base is used usually within a range of 0.1to 5 molar ratios, as opposed to 1 mole of the compound (M-8).

The reaction temperature of the reaction is usually within a range of−20 to 120° C. The reaction period of the react usually within a rangeof 0.1 to 24 hours.

When the reaction is completed, water is added to the reaction mixtures,and the reaction mixtures are extracted with organic solvent(s), and theorganic solvents are worked up (for example, drying and concentration)to give the compound (Ij2)

Process 15

A compound represented by formula (Ij-4) may be prepared by reacting acompound represented by formula (M-9) (hereinafter, referred to asCompound (M-9)) with the compound (R-7) in the presence of a base.

[wherein the symbols are the same as defined above.]

The reaction may be carried out according to the method described inProcess 14.

Process 16

A compound represented by formula (Ik-2) (hereinafter, referred to asCompound (Ik-2)) may be prepared by reacting a compound represented byformula (M-10) (hereinafter, referred to as Compound (M-10)) with acompound represented by formula (R-8) (hereinafter, referred to asCompound (R-8)).

[wherein the symbols are the same as defined above.]

The compound (R-8) is a commercially available compound, or can beprepared by using a known method.

The reaction is usually carried out in the presence of a solvent.Examples of the solvent to be used in the reaction include ethers,halogenated hydrocarbons, aromatic hydrocarbons, aprotic polar solvents,and mixed solvents thereof.

An acid may be added to the reaction as needed, and examples of the acidinclude p-toluenesulfonic acid and 10-camphorsulfonic acid and theothers.

In the reaction, the compound (R-8) is used usually within a range of 1to 10 molar ratio(s), and the acid is used usually within a range of 0.1to 10 molar ratios, as opposed to 1 mole of the compound (M-10).

The reaction temperature is usually within a range of −20 to 180° C. Thereaction period of the reaction is usually within a range of 0.1 to 24hours.

When the reaction is completed, water is added to the reaction mixtures,and the reaction mixtures are extracted with organic solvent (s), andthe organic solvents are worked up (for example, drying andconcentration) to give the compound (Ik-2).

Process 17

The compound (Ik-4) may be prepared by reacting compound represented byformula (M-11) (hereinafter, referred to as Compound (M-11)) with thecompound (R-8).

[wherein the symbols are the same as defined above.]

The reaction may be carried out according to the method described inProcess 16.

Process 18

A compound represented by formula (Im-2) (hereinafter, referred to asCompound (Im-2)) may be prepared by reaction a compound represented byformula (M-12) (hereinafter, referred to as Compound (M-12)) with acompound represented by formula (R-9) (hereinafter, referred to asCompound (R-9).

[wherein the symbols are the same as defined above.]

The compound (R-9) is a commercially available compound, or can beprepared by using a known method.

The reaction is usually carried out in the presence of a solvent.Examples of the solvent to be used in the reaction include ethers,halogenated hydrocarbons, aromatic hydrocarbons, aprotic polar solvents,and mixed solvents thereof.

A base may be added to the reaction as needed, and examples of the baseinclude organic bases.

In the reaction, the compound (R-9) is used usually within a range of 1to 10 molar ratio(s), and the base is used usually within a range of 0.1to 10 molar ratios, as opposed to 1 mole of the compound (M-12).

The reaction temperature is usually within a range of −20 to 120° C. Thereaction period of the reaction is usually within a range of 0.1 to 24hours.

When the reaction is completed, water is added to the reaction mixtures,and the reaction mixtures are extracted with organic solvent(s), and theorganic solvents are worked up (for example, drying and concentration)to give the compound (Im-2).

Process 19

The compound represented by formula (Im-4)) may be prepared by reactinga compound represented by formula (M-13) (hereinafter, referred to asCompound (M-13)) with the compound (R-9).

[wherein the symbols are the same as defined above.]

The reaction nay be carried out according to the method described inProcess 18.

Process 20

A compound represented by formula (In-2) (hereinafter, referred to asCompound (In-2)), a compound represented by formula (Io-2) (hereinafter,referred to as Compound (Io-2)) and a compound represented by formula(Ip-2) (hereinafter, referred to as Compound (Ip-2)) may be preparedaccording to the following method.

[wherein the symbols are the same as defined above.]

First, the process for preparing the compound (In-2) is described.

The compound (In-2)) may be prepared by using a compound represented byformula (M-14) (hereinafter, referred to as Compound (M-14)) in place ofthe compound (M-8) according to the method described in Process 14.

Next, the process for preparing the compound (Io-2) is described.

The compound (Io-2) can be prepared by using the compound (In-2) inplace of the compound (Ia) according to the method described in Process1.

Next, the process for preparing the compound (Ip-2) is described.

The compound (Ip-2) can be prepared by using the compound (Io-2) inplace of the compound (Ib) according to the method described in Process1.

Process 21

A compound represented by formula (In-4) (hereinafter, referred to asCompound (In-4)), a compound represented by formula (Io-4) (hereinafter,referred to as Compound (Io-4)), and a compound represented by formula(Ip-4) (hereinafter referred to as Compound (Ip-4)) can be preparedaccording to the following method.

[wherein the symbols are the same as defined above.]

The reaction may be carried out according to the method described inProcess 20.

Process 22

A compound represented by formula (Iq) (hereinafter, referred to asCompound (Iq)) and a compound represented by formula (Ir) (hereinafter,referred to as Compound (Ir)) may be prepared according to the followingscheme.

[wherein Q³ represents N—CN, N—NO₂, NR⁵, N—C(O)R⁵ or N—C(O)OR¹⁵, and theother symbols are the same as defined above.]

The compound (Iq) may be prepared by using the compound (Ia) accordingto the method described in Organic Letters, 9(19), 3809, 2007.

The compound (Ir) may be prepared by using the compound (Iq) accordingto the method described in Process 1 for preparing the compound (Ib)from the compound (Ia).

Process 23

A compound represented by formula (Is) (hereinafter, referred to asCompound (Is)) and a compound represented by formula (It) (hereinafter,referred to as Compound (It)) may be prepared according to the followingscheme.

[wherein the symbols are the same as defined above.]

The compound (Is) may be prepared by using the compound (Ia), or thecompound (It) may be prepared by using the compound (Is), each accordingto the method described in Russian Journal of Organic Chemistry, Vol,No. 5, 778-779, 2013.

Process 24

A compound represented by formula (Iu-2) (hereinafter, referred to asCompound (Iu-2)) may be prepared by reacting a compound represented byformula (M-25) (hereinafter, referred to as Compound (M-25)) withtrifluoroacetic anhydride in the presence of organic bases. Also, thecompound (Iu-2) may be prepared by reacting the compound (M-25) withacetic anhydride, followed by reacting with methanol.

[wherein, R⁵³ represents a C1-C6 alkyl group optionally having one ormore substituents selected from Group B, a C3-C7 cycloalkyl groupoptionally having one or more substituents selected from Group E, aphenyl group optionally having one or more substituents selected fromGroup H, or a five or six membered aromatic heterocyclic groupoptionally having one or more substituents selected from Group H, andthe other symbols are the same as defined above.]

The reaction may be carried out according to the method described in WO2009/076387.

Process 25

A compound represented by formula (Iv-2) may be prepared by reacting thecompound (Iu-2) with a compound represented by formula (R-20)(hereinafter, referred to as Compound (R-20)) in the presence of a base.

[wherein the symbols are the same as defined above.]

The reaction may be carried out by using the compound (Iu-2) in place ofthe compound (M-4) and using the compound (R-20) in place of thecompound (R-3) according to the method described in Process 6.

The compound (R-20) is a commercially available compound, or can beprepared by using a known method.

Process 26

A compound presented by formula (Iw-2) can be prepared by reacting acompound represented by formula (Iv-2-1) (hereinafter, referred to asCompound (Iv-2-1)) and a compound represented by formula (R-21)(hereinafter, referred to as Compound (R-21)) in the presence of metalcatalyst.

[where, R⁵⁵ represents a C1-C6 chain hydrocarbon group optionally havingone or more substituents selected from Group B, a C3-C7 cycloalkyl groupoptionally having one or more substituents selected from Group E, aphenyl group optionally having one or more substituents selected fromGroup H, or a five or six membered aromatic heterocyclic groupoptionally having one or more substituents selected from Group H, andthe other symbols are the same as defined above.]

The reaction may be carried out by using the compound (Iv-2-1) in placeof the compound (M-2) and using the compound (R-21) in place of thecompound (R-2) according to the method described in Process 4.

The compound (R-21) is a commercially available compound, or can beprepared by using a known method.

Process 27

A compound represented by formula (Iu-4) (hereinafter, referred to asCompound (Iu-4)) may be prepared by reacting a compound represented byformula (M-29) (hereinafter, referred to as Compound (M-29)) withtrifluroacetic anhydride in the presence of organic bases. Also, thecompound (Iu-4) may be prepared by reacting the compound (M-29) withacetic anhydride, followed by reacting with methanol.

[wherein the symbols are the same as defined above.]

The reaction may be carried out according to the method described in WO2009/076387.

Process 28

A compound represented by formula (Iv-4) may be prepared by reacting thecompound (Iu-4) with the compound (R-20) in the presence of a base.

[wherein the symbols are the same as defined above.]

The reaction may be carried out by using the compound (Iu-4) in place ofthe compound (M-4) and using the compound. (R-20) in place of thecompound (R-3) according to the method described in Process 6.

Process 29

A compound represented by formula (Iw-4) ray be prepared by reacting acompound represented by formula (Iv-4-1) (hereinafter, referred to asCompound (Iv-4-1)) with the compound (R-21) in the presence of a metalcatalyst.

[wherein the symbols are the same as defined above.]

The reaction may be carried out by using the compound (Iv-4-1) in placeof the compound (M-2) and using the compound (R-21) in place of thecompound (R-2) according to the method described Process 4.

Process 30

The compound may be prepared by reacting a compound represented byformula (M-30) (hereinafter, referred to as Compound (M-30)) with acompound represented by formula (R-16) (hereinafter, referred to asCompound (R-16)) in the presence of a base.

[wherein x^(a) represents a fluorine atom or a chlorine atom, and theother symbols are the same as defined above.]

The reaction may be carried out by using the compound (M-30) in place ofthe compound (M-2) and using the compound (R-16) in place of thecompound (R-1) according to the method described in Process 2.

The compound (R-16) is a commercially available compound, or can beprepared by using a known method.

Process 31

A compound represented by formula (Ix-2) (hereinafter, referred to asCompound (Ix-2)) may be prepared by reacting a compound represented byformula (M-31) (hereinafter, referred to as Compound (M-31)) with acompound represented by formula (M-1) (hereinafter, referred to asCompound (M-1)) in the presence of a metal catalyst.

[wherein the symbols are the same as defined above.]

The reaction may be carried out by using the compound (M-31) in place ofthe compound (R-2) and using the compound (M-1) in place of the compound(M-2) according to the method described in Process 4.

The compound (M-31) can be prepared by using the method described in thereference process 31 or a known method.

Process 32

A compound represented by formula (4) (hereinafter, referred to asCompound (Ix-4)) may be prepared by reacting a compound represented byformula (M-32) (hereinafter, referred to as Compound (M-32)) with thecompound (M-1) in the presence of a metal catalyst.

[wherein the symbols are the same as defined above.]

The reaction may be carried out by using the compound (M-32) in place ofthe compound (R-2) and using the compound (M-1) in place of the compound(M-2) according to the method described in Process 4.

The compound (M-32) can be prepared by using the method described in thereference process 32 or a known method,

Process 33

The compound (Id-2) may be prepared by reacting a compound representedby formula (M-43) (hereinafter, referred to as Compound (M-43)) with thecompound (R-1) in the presence of a base.

[wherein the symbols are the same as defined above.]

The reaction may be carried out by using the compound (M-43) in place ofthe compound (M-2) according to the method described in Process 2.

Process 34

The compound (Id-4) may be prepared by reacting a compound representedby formula (M-46) (hereinafter, referred to as Compound (M-46)) with thecompound (R-1) in the presence of a base.

[wherein the symbols are the same as defined above.]

The reaction may be carried out by using the compound (M46) in place ofthe compound (M-2) according to the method described in Process 1.

Reference Process 1

The compound (M-2) May be prepared by reacting a compound represented byformula (M-2c) (hereinafter, referred to as Compound (M-2c)) withcompound represented by formula (R-10) (hereinafter, referred to asCompound (R-10)) in the presence of a base.

[wherein the symbols are the same as defined above.]

The reaction may be carried out by using the compound (R-10) in place ofthe compound (M-2) and using the compound (M-2c) in place of thecompound (R-1) according to the method described in Process 2.

The compound (R-10) is a commercially available compound, or can beprepared by using a known method.

Reference Process 2

The compound (M-2c) may be prepared according to the following scheme.

[wherein, R⁵¹ represents a methyl group, an ethyl group, or a benzylgroup, and the other symbols are the same as defined above.]

A compound represented by formula (M-2b) (hereinafter, referred to asCompound (M-2b)) may be prepared by reacting a compound represented byformula (M-2a) (hereinafter, referred to as Compound (M-2a)) with acompound represented by formula (R-11) (hereinafter, referred to asCompound (R-11) in the presence of a base. The reaction may be carriedout according to method described in Process 2.

The compound (M-2c) may be prepared by reacting the compound (M-2b) withan acid. The reaction may be carried out according to the methoddescribed in, for example, WO 2016/052455.

The compound (R-11) is a commercially available compound, or can beprepared by using a known method.

Reference Process 3

The compound (M-2a) may be prepared by reacting a compound representedby formula (R-12) (hereinafter, referred to as Compound (R-12)) with thecompound (M-1) in the presence of a metal catalyst.

[wherein the symbols are the same as defined above.]

The reaction may be carried out by using the compound (M-1) in place ofthe compound (M-2) and using the compound (R-12) in place of thecompound (R-2) according to the method described in Process 4.

The compound (R-12) is a commercially available compound, or can beprepared by using known method.

Reference Process 4

The compound (M-3) may be prepared by reacting a compound represented byformula (M-3c) (hereinafter, referred to as Compound (M-3c)) with thecompound (R-10) in the presence of a base.

[wherein the symbols are the same as defined.]

The reaction may be carried out according to the method described inReference Process 1.

Reference Process 5

The compound (M-3c) may be prepared according to the following scheme.

[wherein the symbols are the same as defined above.]

These reactions may be carried out according to the methods described inReference Process 2.

Reference Process 6

A compound represented by formula (M-3a) may be prepared by reacting acompound represented by formula (R-13) (hereinafter, referred to asCompound (R-13)) with the compound (M-1) in the presence of a metalcatalyst.

[wherein the symbols are the same as defined above.]

The reaction may be carried out according to the method described inReference Process 3.

The compound (R-13) is a commercially available compound, or can beprepared by using a known method.

Reference Process 7

The compound (M-4) may be prepared according to the following scheme.

[wherein the symbols are the same as defined above.]

These reactions may be carried out according to the methods described inReference Process 2.

Reference Process 8

The compound (M-5) may be prepared according to the following scheme.

[wherein the symbols are the same as defined above.]

These reactions may be carried out according to the methods described inReference Process 2.

Reference Process 9

The compound (M-6) may be prepared by reacting the compound (M-2) withdry ice in the presence of a base.

[wherein the symbols are the same as defined above.]

The reaction may be carried out by using dry ice in place of thecompound (R-5) according to the method described in Process 10.

Reference Process 10

The compound (M-7) may be prepared by reacting the compound (M-3) withdry ice in the presence of a base.

[wherein the symbols are the same as defined above.]

The reaction may be carried out by using dry ice in place of thecompound (R-5) according to the method described in Process 10.

Reference Process 11

The compound (M-3) may be prepared by reacting the compound (M-6) with areducing agent.

[wherein the symbols are the same as defined above.]

The reaction is usually carried out in a solvent.

Examples of the solvent to be used in the reaction include ethers,aliphatic hydrocarbons, aromatic hydrocarbons, alcohols, and mixedsolvents thereof.

Examples of the reducing agent to be used in the reaction include sodiumborohydride, lithium borohydride, lithium aluminium hydride,diisobutylaluminum hydride, and the others.

In the reaction, the reducing agent is used usually within a range of 1to 5 molar ratio(s), as opposed to 1 mole of the compound (M-6).

The reaction temperature of the reaction is usually within a range of−20 to 120° C. The reaction period of the reaction is usually within arange of 0.1 to 24 hours.

When the reaction is completed, water is added to the reaction mixtures,and the reaction mixtures are extracted with organic solvent(s), and theorganic solvents are worked up (for example, drying and concentration)to give the compound (M-8).

Reference Process 12

The compound (M-9) may be prepared by reacting the compound (M-7) with areducing agent.

[wherein the symbols are the same as defined above.]

These reactions may be carried out according to the methods described inReference Process 11.

Reference Process 13

The compound (M-10) may be prepared according to the following scheme.

[wherein the symbols are the same as defined above.]

A compound represented by formula (M-10a) (hereinafter, referred to ascompound (M-10a)) may be prepared by using the compound (M-2) in placeof the compound (M-2a) and using p-methoxybenzylamine to in place of thecompound (R-11) according to the method described in Reference Process2.

The compound (M-10) may be prepared by using the compound (M-10a) inplace of the compound (M-2b) according to the method described inReference Process 2.

Reference Process 14

The compound (M-11) may be prepared according to the following scheme.

[wherein the symbols are the same as defined above.]

These reactions may be carried out according to the methods described inReference Process 13.

Reference Process 15

The compound (M-12) may be prepared by reacting the compound (M-2) witha compound represented by formula (R-14) (hereinafter, referred to asCompound (R-14)) in the presence of a base.

[wherein the symbols are the same as defined above.]

The compound (R-14) is a commercially available compound, or can beprepared by using a known method.

The reaction is usually carried out in a solvent.

Examples of the solvent to be used in the reaction include ethers,aromatic hydrocarbons, polar aprotic solvent, and mixed solventsthereof.

Examples of the palladium catalyst include aryl palladium (II) chloride.

In the reaction, phenol as the additive, and potassium tert-butoxide asthe base are used.

In the reaction, the compound (R-14) is usually used within a range of 1to 10 molar ratio(s), the palladium catalyst is usually used within arange of 0.01 to 1 molar ratio(s), phenol is usually used within a rangeof 1 to 5 molar ratio(s) and potassium tert-butoxide is usually usedwithin a range of 0.1 to 10 molar ratios, as opposed to 1 mole of thecompound (M-2).

The reaction temperature of the reaction is usually within a range of 40to 180° C. The reaction period of the reaction is usually within a rangeof 0.1 to 24 hours.

When the reaction is completed, water is added to reaction mixtures, andthe reaction mixtures are extracted with organic solvent(s), and theorganic layers are worked up (for example, drying and concentration) togive the compound (M-12).

Reference Process 16

The compound (M-13) may be prepared by reacting the compound (M-3) withthe compound (R-14) in the presence of a base.

[wherein the symbols are the same as defined above.]

The reaction may be carried out according to the method described inReference process 15.

Reference Process 17

The compound (M-14) may be prepared according to the following scheme.

[wherein the symbols are the same as defined above.]

First, a process for preparing a compound represented by formula (M-14a)(hereinafter, referred to as Compound (M-14a)) is described.

The compound (M-14a) may be prepared by reacting the compound (M-2) withthiobenzoic acid in the presence of a copper catalyst and a base.

The reaction is usually carried out in the presence of a solvent.Examples of the solvent to be used in the reaction include ethers,aromatic hydrocarbons, aprotic polar solvents, water, and mixed solventsthereof.

Examples of the copper catalyst to be used in the reaction includecopper chloride, copper bromide, and copper iodide.

Examples of the base to be used in the reaction include alkali metalhydrides, alkali metal carbonates, and organic bases.

A ligand may be added to the reaction as needed. Examples of the ligandto be used in the reaction include 2,2′-bipyridine, 2-aminoethanol,8-hydroxyquinoline, 1,10-phenanthroline, and the others.

In the reaction, thiobenzoic acid is usually used within a range of 1 to10 molar ratio(s), the copper catalyst is usually used within a range of0.01 to 0.5 molar ratios, the ligand is usually used within a range of0.01 to 1 molar ratio(s), and the base is usually used with a range of0.1 to 5 molar ratios, as opposed to 1 mole of the compound (M-2)

The reaction temperature is usually within a range of −20 to 200° C. Thereaction period of the reaction is usually within a range of 0.1 to 24hours.

When the reaction is completed, water is added to reaction mixtures, andthe reaction mixtures are extracted with organic solvent(s), and theorganic layers are worked up (for example, drying and concentration) togive the compound (M-14a).

Next, the process for preparing the compound (M-14) is described.

The compound (M-14) may be prepared, for example, according to themethod described WO 2011/068171 or the method described in Journal ofOrganic Chemistry, 1978, 43(6), 1190-1192.

Reference Process 18

The compound (M-15) may be prepared according to the following scheme.

[wherein the symbols are the same as defined above.]

These reactions may be carried out according to the methods described inReference Process 17.

Reference Process 19

A compound represented by formula (M-1b) and a compound represented byformula (M-1c) may be prepared by oxidizing a compound represented byformula (M-1a) (hereinafter, referred to as Compound (M-1a)).

[wherein the symbols are the same as defined above.]

These reactions may be carried out according to the methods described inProcess 1.

Reference Process 20

The compound (M-1a) may be prepared by reacting a compound representedby formula (R-15) (hereinafter, referred to as Compound (R-15)) with thecompound (R-16) in the presence of a base.

[wherein the symbols are the same as defined above.]

The reaction may be carried out according to the method described inProcess 2.

The compound (R-15) is commercially available compounds, or can beprepared by using a known method.

Reference Process 21

A compound represented by formula (M-2b-1) (hereinafter, referred to asCompound (M-2b-1)) may be prepared according to the following scheme.

[wherein R⁵⁰ represents a methyl group or an ethyl group, R⁵² and R⁵⁴are identical to or different from each other and each representsindependently a C1-C6 alkyl group, X^(d) represents a fluorine atom, achlorine atom, a bromine atom, an iodine atom, BF₄, or PF₆, and theother symbols are the same as defined above.]

A compound represented by formula (M-17) (hereinafter, referred to asCompound (M-17)) may be prepared by reacting a compound represented byformula (M-16) (hereinafter, referred to as Compound (M-16)) with acompound represented by formula (R-17) (hereinafter, referred to asCompound (R-17)) in the presence of a base.

The reaction is usually carried out in the presence of a solvent.Examples of the solvent to be used in the reaction include alcohols,ethers, aromatic hydrocarbons, aprotic polar solvents, and mixedsolvents thereof.

Examples of the base to be used in the reaction include n-butyl lithium,s-butyl lithium, t-butyl lithium, lithium diisopropylamide, lithiumbis(trimethylsilyl)amide, sodium bis(trimethylsilyl)amide, potassiumbis(trimethylsilyl)amide, potassium t-butoxide, sodium methoxide, sodiumethoxide, and alkali metal hydrides.

In the reaction, the compound (R-17) is usually used within a range of 1to 5 molar ratio(s), and the base is usually used within a range of 1 to5 molar ratio(s), as opposed to 1 mole of the compound (M-16).Preferably, the compound (R-17) is used within a range of 1.0 to 1.1molar ratio(s), and the base is used within a range of 1 to 2 molarratio(s), as opposed to 1 mole of the compound (M-16).

The reaction temperature of the reaction is usually within a range of−78 to 100° C. The reaction period of the reaction is usually within arange of 0.5 to 12 hours.

When the reaction is completed, water is added to reaction mixtures, andthe reaction mixtures are extracted with organic solvent(s), and theorganic layers are worked up (for example, drying and concentration) togive the compound (M-17).

The compound (M-16) is a commercially available compound, or can beprepared by using a known method.

The compound (R-17) is a commercially available compound, or can beprepared by using the method described in Journal of Molecular CatalysisA: Chemical, 2011, 341(1-2), 57.

The compound (M-2b-1) may be prepared by reacting the compound (M-17)with a compound represented by formula (R-18) (hereinafter, referred toas Compound (R-18)), followed by reacting with ammonia.

The step 1 in which the compound (M-17) is reacted with the compound(R-18) is described.

The reaction is usually carried out in a solvent.

Examples of the solvent to be used in the reaction include ethers;aromatic hydrocarbons; halogenated hydrocarbons (such as dichloromethaneand chloroform) (hereinafter, collectively referred to as aliphatichydrocarbons); alcohols; esters; nitriles; aprotic polar solvents;nitrogen-containing aromatic compounds such as pyridine and 2,6-lutidine(hereinafter, collectively referred to as nitrogen-containing aromaticcompounds); and mixed solvents thereof.

A base may be used in the reaction, and examples of the base includealkali metal carbonates, alkali metal hydrides, and organic bases.

When a base is used in the reaction, the base is usually used within arange of 1 to 10 molar ratio(s), as opposed to 1 mole of the compound(M-17).

In the reaction, the compound (R-18) is usually used within a range of 1to 10 molar ratio(s), as opposed to 1 mole of the compound (M-17).

The reaction temperature of the reaction is usually within a range of−50 to 200° C. The reaction period of the reaction is usually within arange of 0.1 to 24 hours.

When the reaction is completed, the reaction mixtures are concentratedto obtain the residues and then the residues are used as itself in thesecond step, or alternatively, water is added to the reaction mixturesand the mixtures are extracted with organic solvents(s), and the organiclayers are worked up (for example, drying and concentration) to obtainthe residues, and then the residues may be used as itself in the secondstep.

Next, the step 2 in which the residues obtained in the step 1 is reactedwith ammonia to obtain the compound (M-2b-1) is described.

The reaction is usually carried out in the presence of a solvent.Examples of the solvents to be used in the reaction include ethers,nitriles, alcohols, aprotic polar solvents, nitrogen-containing aromaticcompounds, and mixed solvents thereof.

Ammonia to be used in the reaction may be used as an aqueous solution oran alcoholic solution thereof.

In the reaction, ammonia is usually used within a range of 1 to 100molar ratio(s), as opposed to 1 mole of the compound (M-17) used in thestep 1.

The reaction temperature of the reaction is usually within a range of 0to 100° C. The reaction period of the reaction is usually within a rangeof 0.1 to 24 hours.

When the reaction is completed, water is added to reaction mixtures, andthe reaction mixtures are extracted with organic solvent(s), and theorganic layers are worked up (for example, drying and concentration) togive the compound (M-2b-1).

The compound (R-18) may be prepared according to the method described inWO 2009/054742.

Reference Process 29

A compound represented by formula (M-2b-2) (hereinafter, referred toCompound (M-2b-2)) may be prepared according to the following scheme.

[wherein X^(e) represents a chlorine atom, a bromine atom, an iodineatom, a methyl group, a nitro group, or a trifluoromethyl group, and theother symbols are the same as defined above.]

A compound represented by formula (M-20) (hereinafter, referred to asCompound (M-20)) may be prepared by reacting the compound (M-17) withammonia.

The reaction is usually carried out in the presence of a solvent.Examples of the solvents to be used in the reaction include ethers,aromatic hydrocarbons, nitriles, alcohols, aprotic polar solvents,water, and mixed solvents thereof.

Ammonia to be used in the reaction may be used as ammoia gas, or may beused as an aqueous solution or an alcoholic solution thereof. Also,ammonium salts including ammonium carboxylate such as ammonium acetate;ammonium phosphate such as ammonium dihydrogen phosphate; ammoniumcarbonate; and ammonium chloride may be used.

In the reaction, ammonia is usually used within a range of 0.1 to 100molar ratios, as opposed to 1 mole of the compound (M-17).

The reaction temperature of the reaction is usually within a range of 0to 200° C. The reaction period of the reaction is usually within a rangeof 0.5 to 24 hours.

When the reaction is completed, water is added to reaction mixtures, andthe reaction mixtures are extracted with organic solvent(s), and theorganic layers are worked up (for example, drying and concentration) togive the compound (M-20).

The compound (M-2b-2) may be prepared by reacting the compound (M-20)with a compound represented by formula (R-19) (hereinafter, referred toas Compound (R-19)).

The reaction is usually carried out in the presence of a solvent.Examples of the solvents to be used in the reaction include ethers,aromatic hydrocarbons, halogenated hydrocarbons, alcohols, esters,nitriles, aprotic polar solvents, nitrogen-containing aromaticcompounds, and mixed solvents thereof.

A base may be used in the reaction, and examples of the base includealkali metal carbonates, alkali metal hydrides, and organic bases.

When a base may be used in the reaction, the base is usually used withina range of 1 to 10 molar ratio(s), as opposed to 1 mole of the compound(M-20).

In the reaction, the compound (R-19) is usually used within a range of 1to 10 molar ratio(s), as opposed to 1 mole of the compound (M-20).

The reaction temperature of the reaction is usually within a range of−50 to 200° C. The reaction period of the reaction is usually within arange of 0.1 to 24 hours.

When the reaction is completed, water is added to reaction mixtures, andthe reaction mixtures are extracted with organic solvent(s), and theorganic layers are worked up (for example, drying and concentration) togive the compound (M-2b-2).

The compound (R-19) may be prepared according to the method described inOrganic Process Research & Development, 2005, 9, 141, or The Journal ofOrganic Chemistry 2000, 65, 4571-4574.

Reference process 23

A compound represented by formula (M-3b-1) (hereinafter, referred to asCompound (M-3b-1)) may be prepared according to the following scheme.

[wherein the symbols are the same as defined above.]

These reactions may be carried out by using the compound (M-18) in placeof the compound (M-16) according to the methods described in ReferenceProcess 21.

Reference process 24

A compound represented by formula (M-3b-2) (hereinafter, referred to asCompound (M-3b-2)) may be prepared according to the following scheme.

[wherein the symbols are the same as defined above.]

These reactions may be carried out by using the compound (M-19) in placeof the compound (M-17) according to the methods described in ReferenceProcess 22.

Reference Process 25

A compound represented by formula (M-22) (hereinafter, referred to asCompound (M-22)) may be prepared by reacting the compound (M-17) withthe compound (R-18), followed by reacting with hydroxyl amine.

[wherein the symbols are the same as defined above.]

The reaction may be carried out by using hydroxyl amine in place ofammonia according to the method described in Reference Process 21 forpreparing the compound (M-2b-1) from the compound (M-17).

Reference Process 26

The compound (M-25) may be prepared according to the following scheme.

[wherein the symbols are the same as defined above.]

A compound represented by formula (M-23) (hereinafter, referred to asCompound (M-23)) may be prepared by using the compound (M-22) in placeof the compound (M-2b) according to the method described in ReferenceProcess 2.

A compound represented by formula (M-24) (hereinafter, referred to asCompound (M-24)) may be prepared by using the compound (M-23) in placeof the compound (M-2c) according to the method described in ReferenceProcess 2.

The compound (M-25) may be prepared by using the compound (M-24) inplace of the compound (M-2) according to the method described in Process2.

Reference Process 27

A compound represented by formula (M-26) (hereinafter, referred to asCompound (M-26)) may be prepared by reacting the compound (M-19) withthe compound (M-18), followed by reacting with hydroxyl amine.

[wherein the symbols are the same as defined above.]

The reaction may be carried out by using the compound (M-19) in place ofthe compound (M-16) and using hydroxyl amine in place of ammonia,according to the method described in Reference Process 21 for preparingthe compound (M-2b-1) from the compound (M-17).

Reference Process 28

The compound (M-29) may be prepared according to the following scheme.

[wherein the symbols are the same as defined above.]

A compound represented by formula (M-27) (hereinafter, referred to asCompound (M-27)) may be prepared by using the compound (M-26) in placeof the compound (M-2b) according to the method described in ReferenceProcess 2.

A compound represented by formula (M-28) (hereinafter, referred to asCompound (M-28)) may be prepared by using the compound (M-27) in placeof the compound (M-2c) according to the method described in ReferenceProcess 2.

A compound represented by formula (M-29) may be prepared by using thecompound (M-28) in place of the compound (M-2) according to the methoddescribed in Process 2.

Reference Process 29

Among the compound (M-30), a compound represented by formula (M-33)wherein Het represents a group represented by formula Het 1 can beprepared by reacting the compound (M-31) and the compound (R-15).

[wherein the symbols are the same as defined above.]

The reaction may be carried out by using the compound (M-31) in place ofthe compound (R-2) and using the compound (R-15) in place of thecompound (M-2) according to the method described in the Process 4.

Reference Process 30

Among the compound (M-30), a compound represented by formula (M-34)wherein Het represents a group represented by formula Het 2 can beprepared by reacting the compound (M-32) and the compound (R-15).

[wherein the symbols are the same as defined above.]

The reaction may be carried out by using the compound (M-32) in place ofthe compound (R-2) and using the compound (R-15) in place of thecompound (M-2) according to the method described in the Process 4.

Reference Process 31

A compound represented by formula (M-37) (hereinafter, referred to asCompound (M-37)) can be prepared according to the following scheme.

[wherein the symbols are the same as defined above.]

A compound represented by formula (M-36) (hereinafter, referred to asCompound (M-36)) can be prepared by reacting a compound represented byformula (M-35) (hereinafter, referred to as Compound (M-35)) and thecompound (R-1). The reaction can be carried out by using the compound(M-35) in place of the compound (M-2) according to the method describedin the Process 2.

The compound (M-37) can be prepared by reacting the compound (M-36 andbis(pinacolato)diboron in the presence of a palladium catalyst and abase. The reaction can be carried out, for example, according the methoddescribed in Journal of Organic Chemistry, 1995, (60), 7508-7510.

The compound (M-35) is a commercially available compound, or can beprepared by using a known method.

Reference Process 32

A compound represented by formula (M-40) (hereinafter, referred to asCompound (M-40)) can be prepared according to the following scheme.

[wherein the symbols are the same as defined above.]

A compound represented by formula (M-39) (hereinafter, referred to asCompound (M-39)) can be prepared by reacting a compound represented byformula (M-38) (hereinafter, referred to as Compound (M-38)) and thecompound (R-1). The reaction can be carried out by using the compound(M-38) in place of the compound (M-2) according to the method describedin the Process 2.

The compound (M-40) can be prepared by reacting the compound (M-39) andbis(pinacolato)diboron in the presence of a palladium catalyst and abase. The reaction can be carried out, for example, according the methoddescribed in Journal of Organic Chemistry, 1995, (60), 7508-7510.

The compound (M-38) is a commercially available compound, or can beprepared by using a known method.

Reference Process 33

A compound represented by formula (M-41) (hereinafter, referred to asCompound (M-41)), a compound represented by formula (M-42) (hereinafter,referred to as Compound (M-42)), and the compound (M-43) can be preparedaccording to the following scheme.

[wherein the symbols are the same as defined above.]

The reaction can be carried out according to the method described in theProcess 20.

The compound (R-22) is a commercially available compound, or can beprepared by using a known method.

Reference Process 34

A compound represented by formula (M-44) (hereinafter, referred to asCompound (M-44)), a compound represented by formula (M-45) (hereinafter,referred to as Compound (M-45)), and the compound (M-46) can be preparedaccording to the following scheme.

[wherein the symbols are the same as defined above.]

The reaction can be carried out according to the method described in theProcess 20.

Examples of the embodiment of the compound (M-36) include the followingcompounds.

Reference Process 35

The compound (M-41) can be prepared by reacting the compound (M-2) andthe compound (R-16) in the presence of a base.

[wherein the symbols are the same as defined above.]

The reaction can be carried out by using the compound (R-16) in place ofthe compound (R-1) according to the method described in the process 2.

Reference Process 36

The compound (M-44) can be Prepared by reacting the compound (M-3) andthe compound (R-16) in the presence of a base.

[wherein the symbols are the dame as defined above.]

The reaction can be carried out by using the compound (R-16) in place ofthe compound (R-1) according to the method described in the process 2.

Embodiment M1

The compound (M-36) wherein A² represents a nitrogen atom or CH, A³represent a nitrogen atom or CH, R⁵ represents a C1-C3 alky group, andT¹ represents a C2-C6 alkoxy group having one or more halogen atoms.

Embodiment M2

The compound according to the embodiment M1 wherein A² represents CH,and A³ represents CH.

Embodiment M3

The compound according to the embodiment M1 wherein A² represents CH,and A³ represent, a nitrogen atom.

Examples of the embodiment of the compound (M-39) include the followingcompounds.

Embodiment M4

The compound (M-39) wherein A² represents a nitrogen atom or CH, A⁴represents a nitrogen atom or CH, R⁵ represents a C1-C3 alkyl group, andT¹ represents a C2-C6 alkoxy group having one or more halogen atoms.

Embodiment M5

The compound according to the embodiment M4 wherein A² represents CH,and A⁴ represents CH.

Embodiment M6

The compound according to the embodiment M4 wherein A² represents CH,and A⁴ represents a nitrogen atom.

Examples of the embodiment of the compound (M-31) includes the followingcompounds.

Embodiment M7

The compound (M-31) wherein A² represents a nitrogen atom or CH, A³represents a nitrogen atom or CH, R⁵ represents a C1-C3 alkyl group, andT represents a C2-C6 alkoxy group having one or more halogen atoms.

Embodiment M8

The compound according to the embodiment M7 wherein A² represents CH,and A³ represents CH.

Embodiment M9

The compound according to the embodiment M7 wherein A² represents CH,and A³ represents a nitrogen atom.

Embodiment M10

The compound according to the embodiment M7 wherein M represents a9-borabicyclo[3,3,1]nonan-9-yl, a borono group, a4,4,5,5,-tetramethyl-1,3,2-dioxaborolan-2-yl, or a tributylstannylgroup.

Examples of the embodiment of the compound (M-32) include the followingcompounds.

Embodiment M11

The compound (M-32) wherein A² represents a nitrogen atom or CH, A⁴represents a nitrogen atom or CH, R⁵ represents a C1-C3 alkyl group, andT represents a C2-C6 alkoxy group having one or more halogen atoms.

Embodiment M12

The compound according to the embodiment M11 wherein A² represents CH,and A⁴ represents CH.

Embodiment M13

The compound according to the embodiment M11 wherein A² represents CH,and A⁴ represents a nitrogen atom.

Embodiment M14

The compound according to the embodiment M11 wherein M represents a9-borabiclo[3,3,1]nonan-9-yl, a borono group, a4,4,5,5,-tetramethyl-1,3,2-dioxaborolan-2-yl, or a tributylstannylgroup.

Next, specific examples of the compound Z of the present invention areindicated below.

Herein, Me represents a methyl group, Et represents an ethyl group, Prrepresents a propyl group, i-Pr represents an isopropyl group, Burepresents a butyl group, c-Pr represents a cyclopropyl group, 1-CN-c-Prrepresents a 1-cyano-cyclopropyl group, Ph represents a phenyl group,Py2 represents a 2-pyridyl group, Py3 represents a 3-pyridyl group, Py4represents a 4-pyridyl group, and Bn represents a benzyl group. When thePh, Py2, Py3, and Py4 have any substituent(s), the substituent(s) isdescribed together with a substitution position before the symbol. Forexample, 4-CF₃-Py2 represents a 4-(trifluoromethyl)-2-pyridyl group, and3,5-(CF₃)₂-Ph represents a 3,5-bis(trifluoromethyl) phenyl group.

A compound represented by formula (L-1):

(hereinafter, referred to as Compound (L-1)) wherein A¹ represents CH,R⁴ represents a hydrogen atom, R⁵ represents a methyl group, and Trepresents any substituents indicated in Table 1 to Table 6(hereinafter, referred to as Compound Class SX₁).

TABLE 1 CF₃ CHF₂ CH₂CF₃ CF₂CF₃ CH₂CF₂CF₃ CF₂CF₂CF₃ CF₂CF₂CF₂CF₃CF₂CF₂CF₂CF₂CF₃ OCF₃ OCHF₂ OCH₂CF₃ OCH₂CHF₂ OCF₂CF₃ OCH(CH₃)CF₃OCH₂CF₂CHF₂ OCH₂CF₂CF₃ OCF₂CF₂CF₃ OCH₂CF₂CHFCF₃ OCH₂CF₂CF₂CF₃OCF₂CF₂CF₂CF₃ OCH₂CF₂CF₂CF₂CF₃ OCH₂CMe₂CN

TABLE 2 SCF₃ SCH₂CF₃ SCF₂CF₃ SCH₂CF₂CF₃ SCF₂CF₂CF₃ SCH₂CF₂CF₂CF₃SCF₂CF₂CF₂CF₃ S(O)CF₃ S(O)CH₂CF₃ S(O)CF₂CF₃ S(O)CH₂CF₂CF₃ S(O)CF₂CF₂CF₃S(O)CH₂CF₂CF₂CF₃ S(O)CF₂CF₂CF₂CF₃ S(O)₂CF₃ S(O)₂CH₂CF₃ S(O)₂CF₂CF₃S(O)₂CH₂CF₂CF₃ S(O)₂CF₂CF₂CF₃ S(O)₂CH₂CF₂CF₂CF₃ S(O)₂CF₂CF₂CF₂CF₃OCH₂(1-CN-c-Pr)

TABLE 3 NHCH₂CF₃ NHCH₂CF₂CF₃ NHCH₂CF₂CF₂CF₃ NMeCH₂CF₃ NMeCH₂CF₂CF₃NMeCH₂CF₂CF₂CF₃ NEtCH₂CF₃ NEtCH₂CF₂CF₃ NEtCH₂CF₂CF₂CF₃ OS(O)₂CF₃OS(O)₂CF₂CF₃ OS(O)₂CF₂CF₂CF₃ CH₂OCF₃ CH₂OCH₂CF₃ CH₂OCF₂CF₃ C(O)CF₃C(O)CF₂CF₃ C(O)CF₂CF₂CF₃ C(O)NMeCH₂CF₃ NMeC(O)CF₃ N═CEtCH₂CF₃OCH₂(1-CN-c-Bu)

TABLE 4 3-CF₃—Ph 4-CF₃—Ph 3,5-(CF₃)₂—Ph 3-SCF₃—Ph 3-S(O)CF₃—Ph3-S(O)₂CF₃—Ph 4-SCF₃—Ph 4-S(O)CF₃—Ph 4-S(O)₂CF₃—Ph

TABLE 5 4-CF₃—Py2 5-CF₃—Py2 4-SCF₃—Py2 4-S(O)CF₃—Py2 4-S(O)₂CF₃—Py25-SCF₃—Py2 5-S(O)CF₃—Py2 5-S(O)₂CF₃—Py2 5-NMeCH₂CF₃—Py2

TABLE 6 5-CF₃—Py3 6-CF₃—Py3 5-SCF₃—Py3 5-S(O)CF₃—Py3 5-S(O)₂CF₃—Py36-SCF₃—Py3 6-S(O)CF₃—Py3 6-S(O)₂CF₃—Py3 6-NMeCH₂CF₃—Py3

A compound (L-1) wherein A¹ represents CH, R⁴ represents a hydrogenatom, R⁵ represents an ethyl group, and T represents any substituentsindicated in Table 1 to Table 6 (hereinafter, referred to as CompoundClass SX₂).

A compound (L-1) wherein A¹ represents a nitrogen atom, R⁴ represents ahydrogen atom, R⁵ represents a methyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₃).

A compound (L-1) wherein A¹ represents a nitrogen atom, R⁴ represents ahydrogen atom, R⁵ represents an ethyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₄).

A compound (L-1) wherein A¹ represents a nitrogen atom, R⁴ represents ahydrogen atom, R⁵ represents a propyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₅).

A compound (L-1) wherein A¹ represents a nitrogen atom, R⁴ represents ahydrogen atom, R⁵ represents an isopropyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₆).

A compound (L-1) wherein A¹ represents a nitrogen atom, R⁴ represents ahydrogen atom, R⁵ represents a cyclopropyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₇).

A compound (L-1) wherein A¹ represents a nitrogen atom, R⁴ represents achlorine atom, R⁵ represents a methyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₈).

A compound (L-1) wherein A¹ represents a nitrogen atom, R⁴ represents achlorine atom, R⁵ represents an ethyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₉).

A compound (L-1) wherein A¹ represents a nitrogen atom, R⁴ represents achlorine atom, R⁵ represents a propyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₁₀).

A compound (L-1) wherein A¹ represents a nitrogen atom, R⁴ represents achlorine atom, R⁵ represents an isopropyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₁₁).

A compound (L-1) wherein A¹ represents a nitrogen atom, R⁴ represents achlorine atom, R⁵ represents a cyclopropyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₁₂).

A compound represented by formula (L-2):

(hereinafter, referred to as Compound (L-2)) wherein A¹ represents CH,R⁵ represents a methyl group, and T represents any substituentsindicated in Table 1 to Table 6 (hereinafter, referred to as CompoundClass SX₁₃).

A compound (L-2) wherein A¹ represents CH, R⁵ represents an ethyl group,and T represents any substituents indicated in Table 1 to Table 6(hereinafter, referred to as Compound Class SX₁₄).

A compound (L-2) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, and T represents any substituents indicated in Table 1 toTable 6 (hereinafter, referred to as Compound Class SX₁₅).

A compound (L-2) wherein A¹ represents a nitrogen atom, R⁵ represents anethyl group, and T represents any substituents indicated in Table 1 toTable 6 (hereinafter, referred to as Compound Class SX₁₆).

A compound (L-2) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, and T represents any substituents indicated in Table 1 toTable 6 (hereinafter, referred to as Compound Class SX₁₇).

A compound (L-2) wherein A¹ represents a nitrogen atom, R⁵ represents anisopropyl group, and T represents any substituents indicated in Table 1to Table 6 (hereinafter, referred to as Compound Class SX₁₈).

A compound (L-2) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, and T represents any substituents indicated in Table1 to Table 6 (hereinafter, referred to as Compound Class SX₁₉).

A compound represented by formula (L-3):

(hereinafter, referred to as Compound (L-3)) wherein A¹ represents CH,R⁴ represents a hydrogen atom, R⁵ represents a methyl group, and Trepresents any substituents indicated in Table 1 to Table 6(hereinafter, referred to as Compound Class SX₂₀).

A compound (L-3) wherein A¹ represents CH, R⁴ represents a hydrogenatom, R⁵ represents an ethyl group, and T represents any substituentsindicated in Table 1 to Table 6 (hereinafter, referred to as CompoundClass SX₂₁).

A compound (L-3) wherein A¹ represents a nitrogen atom, R⁴ represents ahydrogen atom, R⁵ represents a methyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₂₂).

A compound (L-3) wherein A¹ represents a nitrogen atom, R⁴ represents ahydrogen atom, R⁵ represents an ethyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₂₃).

A compound (L-3) wherein A¹ represents a nitrogen atom, R⁴ represents ahydrogen atom, R⁵ represents a propyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₂₄).

A compound (L-3) wherein A¹ represents a nitrogen atom, R⁴ represents ahydrogen atom, R⁵ represents an isopropyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₂₅).

A compound (L-3) wherein A¹ represents a nitrogen atom, R⁴ represents ahydrogen atom, R⁵ represents a cyclopropyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₂₆).

A compound (L-3) wherein A¹ represents a nitrogen atom, R⁴ represents achlorine atom, R⁵ represents a methyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₂₇).

A compound (L-3) wherein A¹ represents a nitrogen atom, R⁴ represents achlorine atom, R⁵ represents an ethyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₂₈).

A compound (L-3) wherein A¹ represents a nitrogen atom, R⁴ represents achlorine atom, R⁵ represents a propyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₂₉).

A compound (L-3) wherein A¹ represents a nitrogen atom, R⁴ represents achlorine atom, R⁵ represents an isopropyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₃₀).

A compound (L-3) wherein A¹ represents a nitrogen atom, R⁴ represents achlorine atom, R⁵ represents a cyclopropyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₃₁).

A compound represented by formula (L-4):

(hereinafter, referred to as Compound (L-4)) wherein A¹ represents CH,R⁵ represents a methyl group, and T represents any substituentsindicated in Table 1 to Table 6 (hereinafter, referred to as CompoundClass SX₃₂).

A compound (L-4) wherein A¹ represents CH, R⁵ represents an ethyl group,and T represents any substituents indicated in Table 1 to Table 6(hereinafter, referred to as Compound Class SX₃₃).

A compound (L-4) wherein A¹ represents a nitrogen atom, represents amethyl group, and T represent any substituents indicated in Table 1 toTable 6 (hereinafter, referred to as Compound Class SX₃₄).

A compound (L-4) wherein A¹ represents a nitrogen atom, R⁵ represents anethyl group, and T represents any substituents indicated in Table 1 toTable 6 (hereinafter, referred to as Compound Class SX₃₅).

A compound (L-4) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, and T represents any substituents indicated in Table 1 toTable 6 (hereinafter, referred to as Compound Class SX₃₆).

A compound (L-4) wherein A¹ represents a nitrogen atom, R⁵ represents anisopropyl group, and T represents any substituents indicated in Table 1to Table 6 (hereinafter, referred to as Compound Class SX₃₇).

A compound (L-4) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, and T represents any substituents indicated in Table1 to Table 6 (hereinafter, referred to as Compound Class SX₃₈).

A compound represented by formula (L-5):

(hereinafter, referred to as Compound (L-5)) wherein A¹ represents CH,R⁴ represents a hydrogen atom, R⁵ represents a methyl group, and Trepresents any substituents indicated in Table 1 to Table 6(hereinafter, referred to as Compound Class SX₃₉).

A compound (L-5) wherein A¹ represents CH, R⁴ represents a hydrogenatom, R⁵ represents an ethyl group, and represents any substituentsindicated in Table 1 to Table 6 (hereinafter, referred to as CompoundClass SX₄₀).

A compound (L-5) wherein A¹ represents a nitrogen atom, R⁴ represents ahydrogen atom, R⁵ represents a methyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₄₁).

A compound (L-5) wherein A¹ represents a nitrogen atom, R⁴ represents ahydrogen atom, R⁵ represents an ethyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₄₂).

A compound (L-5) wherein A¹ represents a nitrogen atom, R⁴ represents ahydrogen atom, R⁵ represents a propyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₄₃).

A compound (L-5) wherein A¹ represents a nitrogen atom, R⁴ represents ahydrogen atom, R⁵ represents an isopropyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₁₄).

A compound (L-5) wherein A¹ represents a nitrogen atom, R⁴ represents ahydrogen atom, R⁵ represents a cyclopropyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₄₅).

A compound (L-5) wherein A¹ represents a nitrogen atom, R⁴ representschlorine atom, R⁵ represents a methyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₄₆).

A compound (L-5) wherein A¹ represents a nitrogen atom, R⁴ represents achlorine atom, R⁵ represents an ethyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₄₇).

A compound (L-5) wherein A¹ represents a nitrogen atom, R⁴ represents achlorine atom, R⁵ represents a propyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₄₈).

A compound (L-5) wherein A¹ represents a nitrogen atom, R⁴ represents achlorine atom, R⁵ represents an isopropyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₄₉).

A compound (L-5) wherein A¹ represents a nitrogen atom, R⁴ represents achlorine atom, R⁵ represents a cyclopropyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₅₀).

A compound represented by formula (L-6):

(hereinafter, referred to as Compound (L-6)) wherein A¹ represents CH,R⁵ represents a methyl group, and T represents any substituentsindicated in Table 1 to Table 6 (hereinafter, referred to as CompoundClass SX₅₁).

A compound (L-6) wherein A¹ represents CH, R⁵ represents an ethyl group,and T represents any substituents indicated in Table 1 to Table 6(hereinafter, referred to as Compound Class SX₅₂).

A compound (L-6) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, and T represents any substituents indicated in Table 1 toTable 6 (hereinafter, referred to as Compound Class SX₅₃).

A compound (L-6) wherein A¹ represents a nitrogen atom, R⁵ represents anethyl group, and T represents any substituents indicated in Table 1 toTable 6 (hereinafter, referred to as Compound Class SX₅₄).

A compound (L-6) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, and T represents any substituents indicated in Table 1 toTable 6 (hereinafter, referred to as Compound Class SX₅₅).

A compound (L-6) wherein A¹ represents a nitrogen atom, R⁵ represents anisopropyl group, and T represents any substituents indicated in Table 1to Table 6 (hereinafter, referred to as Compound Class SX₅₆).

A compound (L-6) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, and T represents any substituents indicated in Table1 to Table 6 (hereinafter, referred to as Compound Class SX₅₇).

A compound represented by formula (L-7):

(hereinafter, referred to as Compound (L-7)) wherein A¹ represents CH,R⁴ represents a hydrogen atom, R⁵ represents a methyl group, and Trepresents any substituents indicated in Table 1 to Table 6(hereinafter, referred to as Compound Class SX₅₈).

A compound (L-7) wherein A¹ represents CH, R⁴ represents a hydrogenatom, R⁵ represents an ethyl group, and T represents any substituentsindicated in Table 1 to Table 6 (hereinafter, referred to as CompoundClass SX₅₉).

A compound (L-7) wherein A¹ represents a nitrogen atom, R⁴ represents ahydrogen atom, R⁵ represents a methyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₆₀).

A compound (L-7) wherein A¹ represents a nitrogen atom, R⁴ represents ahydrogen atom, R⁵ represents an ethyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₆₁).

A compound (L-7) wherein A¹ represents a nitrogen atom, R⁴ represents ahydrogen atom, R⁵ represents a propyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₆₂).

A compound (L-7) wherein A¹ represents a nitrogen atom, R⁴ represents ahydrogen atom, R⁵ represents an isopropyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₆₃).

A compound (L-7) wherein A¹ represents a nitrogen atom, R⁴ represents ahydrogen atom, R⁵ represents a cyclopropyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₆₄).

A compound (L-7) wherein A¹ represents a nitrogen atom, R⁴ represents achlorine atom, R⁵ represents a methyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₆₅).

A compound (L-7) wherein A¹ represents a nitrogen atom, R⁴ represents achlorine atom, R⁵ represents an ethyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₆₆).

A compound (L-7) wherein A¹ represents a nitrogen atom, R⁴ represents achlorine atom, R⁵ represents a propyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₆₇).

A compound (L-7) wherein A¹ represents a nitrogen atom, R⁴ represents achlorine atom, R⁵ represents an isopropyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₆₈).

A compound (L-7) wherein A¹ represents a nitrogen atom, R⁴ represents achlorine atom, R⁵ represents a cyclopropyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₆₉).

A compound represented by formula (L-8):

(hereinafter, referred to as Compound (L-8)) wherein A¹ represents CH,R⁵ represents a methyl group, and T represents any substituentsindicated in Table 1 to Table 6 (hereinafter, referred to as CompoundClass SX₇₀).

A compound (L-8) wherein A¹ represents CH, R⁵ represents an ethyl group,and T represents any substituents indicated in Table 1 to Table 6(hereinafter, referred to as Compound Class SX₇₁).

A compound (L-8) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, and T represents any substituents indicated in Table 1 toTable 6 (hereinafter, referred to as Compound Class SX₇₂).

A compound (L-8) wherein A¹ represents a nitrogen atom, R⁵ represents anethyl group, and T represents any substituents indicated in Table 1 toTable 6 (hereinafter, referred to as Compound Class SX₇₃).

A compound (L-8) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, and T represents any substituents indicated in Table 1 toTable 6 (hereinafter, referred to as Compound Class SX₇₄).

A compound (L-8) wherein A¹ represents a nitrogen atom, R⁵ represents anisopropyl group, and T represents any substituents indicated in Table 1to Table 6 (hereinafter, referred to as Compound Class SX₇₅).

A compound (L-8) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, and T represents any substituents indicated in Table1 to Table 6 (hereinafter, referred to as Compound Class SX₇₆).

A compound represented by formula (L-9):

(hereinafter, referred to as Compound (L-9)) wherein A¹ represents CH,R⁵ represents a methyl group, R^(3b) represents a hydrogen atom, andR^(3c) represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₇₇).

TABLE 7 F Cl Br Me Et Pr i-Pr c-Pr 1-CN-c-Pr OMe OEt OPr Oi-Pr CF₃ NH₂NHCH₂CF₃ CN C(O)OEt NHC(O)c-Pr NMeC(O)c-Pr CH═N—OH CH═N—OMe

TABLE 8 Ph 3-F—Ph 4-F—Ph 3-Cl—Ph 4-Cl—Ph 3-CF₃—Ph 4-CF₃—Ph 3-NMe₂—Ph4-NMe₂—Ph 3-CN—Ph 4-CN—Ph 4-C(O)NMe₂—Ph 4-NHC(O)Me—Ph 3,4-F₂—Ph3,5-F₂—Ph 2,4-F₂—Ph 3,4,5-F₃—Ph 3,4-Cl₂—Ph 3,5-Cl₂—Ph 3,5-Cl₂-4-F—Ph OPhO-2-F—Ph

TABLE 9 Py2 4-F-Py2 5-F-Py2 4-Cl-Py2 5-Cl-Py2 4-CF₃-Py2 5-CF₃-Py23-Me-Py2 4-Me-Py2 5-Me-Py2 6-Me-Py2 5-CN-Py2 5-OCH₂CF₂CF₃-Py2 3,5-F₂-Py2Py3 6-CF₃-Py3 5-CF₃-Py3 6-F-Py3 6-Cl-Py3 Py4 OPy2 OPy3

TABLE 10

TABLE 11

TABLE 12

TABLE 13

TABLE 14

TABLE 15

A compound (L-9) wherein A¹ represents CH, R⁵ represents an ethyl group,R^(3b) represents a hydrogen atom, and R^(3c) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₇₈).

A compound (L-9) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₇₉).

A compound (L-9) wherein A¹ represents a nitrogen atom, R⁵ represents anethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₈₀).

A compound (L-9) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₈₁).

A compound (L-9) wherein A¹ represents a nitrogen atom, R⁵ represents anisopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₈₂).

A compound (L-9) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₈₃).

A compound (L-9) wherein A¹ represents CH, R⁵ represents a methyl group,R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₈₄).

A compound (L-9) wherein A¹ represents CH, R⁵ represents an ethyl group,R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₈₅),

A compound (L-9) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₈₆).

A compound (L-9) wherein A¹ represents a nitrogen atom, R⁵ represents anethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₈₇).

A compound (L-9) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₈₈).

A compound (L-9) wherein A¹ represents a nitrogen atom, R⁵ represents anisopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₈₉).

A compound (L-9) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₉₀).

A compound represented by formula (L-10):

(hereinafter, referred to as Compound (L-10)) wherein A¹ represents CH,R⁵ represents a methyl group, R^(3b) represents a hydrogen atom, andR^(3c) represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₉₁).

A compound (L-10) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3b) represents a hydrogen atom, and R^(3c) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₉₂).

A compound (L-10) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₉₃).

A compound (L-10) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 thereinafter, referredto as Compound Class SX₉₄).

A compound (L-10) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₉₅).

A compound (L-10) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as compound Class SX₉₆).

A compound (L-10) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₉₇).

A compound (L-10) wherein A¹ represents CH, R⁵ represents a methylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₉₈).

A compound (L-10) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₉₉).

A compound (L-10) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₁₀₀).

A compound (L-10) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₁₀₁).

A compound (L-10) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₁₀₂).

A compound (L-10) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₁₀₃).

A compound (L-10) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₁₀₄).

A compound represented by formula (L-11):

(hereinafter, referred to as Compound (L-11)) wherein A¹ represents CH,R⁵ represents a methyl group, R^(3b) represents a hydrogen atom, andR^(3c) represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₁₀₅).

A compound (L-11) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3b) represents a hydrogen atom, and R^(3c) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₁₀₆).

A compound (L-11) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₁₀₇).

A compound (L-11) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₁₀₈).

A compound (L-11) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₁₀₉).

A compound (L-11) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₁₁₀).

A compound (L-11) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituent, indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₁₁₁).

A compound (L-11) wherein A¹ represents CH, R⁵ represents a methylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₁₁₂).

A compound (L-11) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₁₁₃).

A compound (L-11) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₁₁₄).

A compound (L-11) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₁₁₅).

A compound (L-11) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₁₁₆).

A compound (L-11) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₁₁₇).

A compound (L-11) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX¹¹⁸).

A compound represented by formula (L-12):

(hereinafter, referred to as Compound (L-12)) wherein A¹ represents CH,R⁵ represents a methyl group, R^(3b) represents a hydrogen atom, andR^(3c) represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₁₁₉).

A compound (L-12) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3b) represents a hydrogen atom, and R^(3c) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₁₂₀).

A compound (L-12) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₁₂₁).

A compound (L-12) wherein A¹ represents a nitrogen atom, R⁵ representsethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₁₂₂).

A compound (L-12) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₁₂₃).

A compound (L-12) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₁₂₄).

A compound (L-12) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₁₂₅).

A compound (L-12) wherein A¹ represents CH, R⁵ represents a methylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₁₂₆).

A compound (L-12) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₁₂₇).

A compound (L-12) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₁₂₈).

A compound (L-12) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₁₂₉).

A compound (L-12) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₁₃₀).

A compound (L-12) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₁₃₁).

A compound (L-12) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₁₃₂).

A compound represented by formula L-13):

(hereinafter, referred to as Compound (L-13)) wherein A¹ represents CH,R⁵ represents a methyl group, R^(3b) represents a hydrogen atom, andR^(3c) represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₁₃₃).

A compound (L-13) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3b) represents a hydrogen atom, and R^(3c) represents anysubstituents indicated in Table 7 Table 15 (hereinafter, referred to asCompound Class SX₁₃₄).

A compound (L-13) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₁₃₅).

A compound (L-13) wherein, A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₁₃₆).

A compound (L-13) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₁₃₇).

A compound (L-13) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX¹³⁸).

A compound (L-13) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₁₃₉).

A compound (L-13) wherein A¹ represents CH, R⁵ represents a methylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₁₄₀).

A compound (L-13) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX¹⁴¹).

A compound (L-13) wherein A¹ represents a nitrogen atom, and R⁵represents a methyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX¹⁴²).

A compound (L-13) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₁₄₃).

A compound (L-13) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₁₄₄).

A compound (L-13) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₁₄₅).

A compound (L-13) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₁₄₆).

A compound represented by formula (L-14):

(hereinafter, referred to as Compound (L-14)) wherein A¹ represents CH,R⁵ represents a methyl group, R^(3b) represents a hydrogen atom, andR^(3c) represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₁₄₇).

A compound (L-14) wherein A¹ represents CH, R⁵ represents an ethyl groupR^(3b) represents a hydrogen atom, and R^(3c) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₁₄₈).

A compound (L-14) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₁₄₉).

A compound (L-14) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₁₅₀).

A compound (L-14) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₁₅₁).

A compound (L-14) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₁₅₂).

A compound (L-14) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represent any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₁₅₃).

A compound (L-14) wherein A¹ represents CH, R⁵ represents a methylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₁₅₄).

A compound (L-14) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₁₅₅).

A compound (L-14) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₁₅₆).

A compound (L-14) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₁₅₇).

A compound (L-14) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₁₅₈).

A compound (L-14) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₁₅₉).

A compound (L-14) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₁₆₀).

A compound represented by formula (L-15):

(hereinafter, referred to as Compound (L-15)) wherein A¹ represents CH,R⁵ represents a methyl group, R^(3b) represents a hydrogen atom, andR^(3c) represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₁₆₁).

A compound (L-15) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3b) represents a hydrogen atom, and R^(3c) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₁₆₂).

A compound (L-15) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₁₆₃).

A compound (L-15) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₁₆₄).

A compound (L-15) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₁₆₅).

A compound (L-15) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₁₆₆).

A compound (L-15) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₁₆₇).

A compound (L-15) wherein A¹ represents CH, R⁵ represents a methylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₁₆₈).

A compound (L-15) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₁₆₉).

A compound (L-15) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₁₇₀).

A compound (L-15) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₁₇₁).

A compound (L-15) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₁₇₂).

A compound (L-15) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₁₇₃).

A compound (L-15) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₁₇₄).

A compound represented by formula (L-16):

(hereinafter, referred to as Compound (L-16)) wherein A¹ represents CH,R⁵ represents a methyl group, R^(3b) represents a hydrogen atom, andR^(3c) represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₁₇₅).

A compound (L-16) wherein A¹ represent CH, R⁵ represents an ethyl group,R^(3b) represents a hydrogen atom, and R^(3c) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₁₇₆).

A compound (L-16) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₁₇₇).

A compound (L-15) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₁₇₈).

A compound (L-16) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₁₇₉).

A compound (L-16) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₁₈₀).

A compound (L-16) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₁₈₁).

A compound (L-16) wherein A¹ represents CH, R⁵ represents a methylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₁₈₂).

A compound (L-16) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₁₈₃).

A compound (L-15) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₁₈₄).

A compound (L-16) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₁₈₅).

A compound (L-6) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₁₈₆).

A compound (L-16) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₁₈₇).

A compound (L-16) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3b) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₁₈₈).

A compound represented by formula (L-17):

(hereinafter, referred Compound (L-17)) wherein A¹ represents CH, R⁵represents a methyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₁₈₉).

A compound (L-17) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3b) represents a hydrogen atom, and R^(3c) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₁₉₀).

A compound (L-17) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₁₉₁).

A compound (L-17) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₁₉₂).

A compound (L-17) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₁₉₃).

A compound (L-17) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₁₉₄).

A compound (L-17) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₁₉₅).

A compound (L-17) wherein A¹ represents CH, R⁵ represents a methylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₁₉₆).

A compound (L-17) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₁₉₇).

A compound (L-17) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₁₉₈).

A compound (L-17) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₁₉₉).

A compound (L-17) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₂₀₀).

A compound (L-17) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₂₀₁).

A compound (L-17) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₂₀₂).

A compound represented by formula (L-18):

(hereinafter, referred to as Compound (L-18)) wherein A¹ represents CH,R⁵ represents a methyl group, R^(3b) represents a hydrogen atom, andR^(3c) represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₂₀₃).

A compound (L-18) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3b) represents a hydrogen atom, and R^(3c) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₂₀₄).

A compound (L-18) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₂₀₅).

A compound (L-18) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₂₀₆).

A compound (L-18) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₂₀₇).

A compound (L-18) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₂₀₈).

A compound (L-18) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₂₀₉).

A compound (L-18) wherein A¹ represents CH, R⁵ represents a methylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₂₁₀).

A compound (L-18) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₂₁₁).

A compound (L-18) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₂₁₂).

A compound (L-18) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₂₁₃).

A compound (L-18) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₂₁₄).

A compound (L-18) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represent any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₂₁₅).

A compound (L-18) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₂₁₆).

A compound represented by formula (L-19):

(hereinafter, referred to as Compound (L-19)) wherein A¹ represents CH,R⁵ represents a methyl group, R^(3b) represents a hydrogen atom, andR^(3c) represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₂₁₇).

A compound (L-19) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3b) represents a hydrogen atom, and R^(3c) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₂₁₈).

A compound (L-19) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₂₁₉).

A compound (L-19) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₂₂₀).

A compound (L-19) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₂₂₁).

A compound (L-19) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₂₂₂).

A compound (L-19) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₂₂₃).

A compound (L-19) wherein A¹ represents CH, R⁵ represents a methylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₂₂₄).

A compound (L-19) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₂₂₅).

A compound (L-19) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₂₂₆).

A compound (L-19) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₂₂₇).

A compound (L-19) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₂₂₈).

A compound (L-19) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₂₂₉).

A compound (L-19) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₂₃₀).

A compound represented by formula (L-20):

(hereinafter, referred to as Compound (L-20)) wherein A¹ represents CH,R⁵ represents a methyl group, R^(3b) represents a hydrogen atom, andR^(3c) represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₂₃₁).

A compound (L-20) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3b) represents a hydrogen atom, and R^(3c) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₂₃₂).

A compound (L-20) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₂₃₃).

A compound (L-20) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₂₃₄).

A compound (L-20) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₂₃₅).

A compound (L-20) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₂₃₆).

A compound (L-20) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₂₃₇).

A compound (L-20) wherein A¹ represents CH, R⁵ represents a methylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₂₃₈).

A compound (L-20) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₂₃₉).

A compound (L-20) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₂₄₀).

A compound (L-20) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₂₄₁).

A compound (L-20) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₂₄₂).

A compound (L-20) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₂₄₃).

A compound (L-20) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₂₄₄).

A compound represented by formula (L-21):

(hereinafter, referred to as Compound (L-21)) wherein A¹ represents CH,R⁵ represents a methyl group, R^(3b) represents a hydrogen atom, andR^(3c) represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₂₄₅).

A compound (L-21) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3b) represents a hydrogen atom, and R^(3c) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₂₄₆).

A compound (L-21) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3b) represent a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₂₄₇).

A compound (L-21) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₂₄₈).

A compound (L-21) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₂₄₉).

A compound (L-21) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₂₅₀).

A compound (L-21) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₂₅₁).

A compound (L-21) wherein A¹ represents CH, R⁵ represents a methylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₂₅₂).

A compound (L-21) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₂₅₃).

A compound (L-21) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₂₅₄).

A compound (L-21) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₂₅₅).

A compound (L-21) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₂₅₆).

A compound (L-21) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₂₅₇).

A compound (L-21) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₂₅₈).

A compound represented by formula (L-22):

(hereinafter, referred to as Compound (L-22)) wherein A¹ represents CH,R⁵ represents a methyl group, R^(3b) represents a hydrogen atom, andR^(3c) represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₂₅₉).

A compound (L-22) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3b) represents a hydrogen atom, and R^(3c) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₂₆₀).

A compound (L-22) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₂₆₁).

A compound (L-22) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₂₆₂).

A compound (L-22) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₂₆₃).

A compound (L-22) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₂₆₄).

A compound (L-22) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₂₆₅).

A compound (L-22) wherein A¹ represents CH, R⁵ represents a methylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₂₆₆).

A compound (L-22) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₂₆₇).

A compound (L-22) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₂₆₈).

A compound (L-22) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₂₆₉).

A compound (L-22) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₂₇₀).

A compound (L-22) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₂₇₁).

A compound (L-22) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₂₇₂).

A compound represented by formula (L-23):

(hereinafter, referred to as Compound (L-23)) wherein A¹ represents CH,R⁵ represents a methyl group, R^(3b) represents a hydrogen atom, andR^(3c) represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₂₇₃).

A compound (L-23) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3b) represents a hydrogen atom, and R^(3c) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₂₇₄).

A compound (L-23) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₂₇₅).

A compound (L-23) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₂₇₆).

A compound (L-23) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₂₇₇).

A compound (L-23) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3b) represents a hydrogen at and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₂₇₈).

A compound (L-23) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₂₇₉).

A compound (L-23) wherein A¹ represents CH, R⁵ represents a methylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₂₈₀).

A compound (L-23) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₂₈₁).

A compound (L-23) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₂₈₂).

A compound (L-23) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₂₈₃).

A compound (L-23) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₂₈₄).

A compound (L-23) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₂₈₅).

A compound (L-23) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₂₈₆).

A compound represented by formula (L-24):

(hereinafter, referred to as Compound (L-24)) wherein A¹ represents CH,R⁵ represents a methyl group, R^(3b) represents a hydrogen atom, andR^(3c) represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₂₈₇).

A compound (L-24) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3b) represents a hydrogen atom, and R^(3c) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₂₈₈).

A compound (L-24) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₂₈₉).

A compound (L-24) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₂₉₀).

A compound (L-24) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₂₉₁).

A compound (L-24) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₂₉₂).

A compound (L-24) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₂₉₃).

A compound (L-24) wherein A¹ represents CH, R⁵ represents a methylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₂₉₄).

A compound (L-24) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₂₉₅).

A compound (L-24) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₂₉₆).

A compound (L-24) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₂₉₇).

A compound (L-24) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₂₉₈).

A compound (L-24) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 1(hereinafter, referred to as Compound Class SX₂₉₉).

A compound (L-24) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₃₀₀).

A compound represented by formula (L-25):

(hereinafter, referred to as Compound (L-24)) wherein A¹ represents CH,R⁵ represents a methyl group, R^(3b) represents a hydrogen atom, andR^(3c) represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₃₀₁).

A compound (L-25) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3b) represents a hydrogen atom, and R^(3c) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₃₀₂).

A compound (L-25) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₃₀₃).

A compound (L-25) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₃₀₄).

A compound (L-25) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₃₀₅).

A compound (L-25) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₃₀₆).

A compound (L-25) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₃₀₇).

A compound (L-25) wherein A¹ represents CH, R⁵ represents a methylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₃₀₈).

A compound (L-25) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₃₀₉).

A compound (L-25) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₃₁₀).

A compound (L-25) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₃₁₁).

A compound (L-25) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₃₁₂).

A compound (L-25) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₃₁₃).

A compound (L-25) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₃₁₄).

A compound represented by formula (L-26):

(hereinafter, referred to as Compound (L-26)) wherein A¹ represents CH,R⁵ represents a methyl group, R^(3b) represents a hydrogen atom, andR^(3c) represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₃₁₅).

A compound (L-26) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3b) represents a hydrogen atom, and R^(3c) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₃₁₆).

A compound (L-26) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₃₁₇).

A compound (L-26) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₃₁₈).

A compound (L-26) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₃₁₉).

A compound (L-26) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₃₂₀).

A compound (L-26) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₃₂₁).

A compound (L-26) wherein A¹ represents CH, R⁵ represents a methylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₃₂₂).

A compound (L-26) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₃₂₃).

A compound (L-26) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₃₂₄).

A compound (L-26) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3c) represents a hydrogen atom, Table 15(hereinafter, referred to as Compound class SX₃₂₅).

A compound (L-26) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₃₂₆).

A compound (L-26) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₃₂₇).

A compound (L-26) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₃₂₈).

A compound represented by formula (L-27):

(hereinafter, referred to as Compound (L-27)) wherein A¹ represents CH,R⁵ represents a methyl group, R^(3b) represents a hydrogen atom, andR^(3c) represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₃₂₉).

A compound (L-27) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3b) represents a hydrogen atom, and R^(3c) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₃₃₀).

A compound (L-27) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₃₃₁).

A compound (L-27) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₃₃₂).

A compound (L-27) wherein A¹ represents a nitrogen atom, R⁵ represents apropel group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₃₃₃).

A compound (L-27) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₁₃₄).

A compound (L-27) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₃₃₅).

A compound (L-27) wherein A¹ represents CH, R⁵ represents a methylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₃₃₆).

A compound (L-27) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₃₃₇).

A compound (L-27) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₃₃₈).

A compound (L-27) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₃₃₉).

A compound (L-27) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₃₄₀).

A compound (L-27) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₃₄₁).

A compound (L-27) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₃₄₂).

A compound represented by formula (L-28):

(hereinafter, referred to as Compound (L-28)) wherein A¹ represents CH,R⁵ represents a methyl group, R^(3b) represents a hydrogen atom, andR^(3c) represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₃₄₃).

A compound (L-28) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3b) represents a hydrogen atom, and R^(3c) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₃₄₄).

A compound (L-28) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredCompound Class SX₃₄₅).

A compound (L-28) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₃₄₆).

A compound (L-28) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₃₄₇).

A compound (L-28) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₃₄₈).

A compound (L-28) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₃₄₉).

A compound (L-28) wherein A¹ represents CH, R⁵ represents a methylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₃₅₀).

A compound (L-28) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₃₅₁).

A compound (L-28) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₃₅₂).

A compound (L-28) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₃₅₃).

A compound (L-28) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₃₅₄).

A compound (L-28) wherein A¹ represents nitrogen atom, R⁵ represents anisopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₃₅₅).

A compound (L-28) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₃₅₆).

A compound represented by formula (L-29):

(hereinafter, referred to as Compound (L-29)) wherein A¹ represents CH,R⁵ represents a methyl group, R^(3b) represents a hydrogen atom, andR^(3c) represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₃₅₇).

A compound (L-29) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3b) represents a hydrogen atom, and R^(3c) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₃₅₈).

A compound (L-29) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₃₅₉).

A compound (L-29) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₃₆₀).

A compound (L-29) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₃₆₁).

A compound (L-29) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₃₆₂).

A compound (L-29) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₃₆₃).

A compound (L-29) wherein A¹ represents CH, R⁵ represents a methylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₃₆₄).

A compound (L-29) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₃₆₅).

A compound (L-29) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₃₆₆).

A compound (L-29) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₃₆₇).

A compound (L-29) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₃₆₈).

A compound (L-29) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₃₆₉).

A compound (L-29) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₃₇₀).

A compound represented by formula (L-30):

(hereinafter, referred to as Compound (L-30)) wherein A¹ represents CH,R⁵ represents a methyl group, R^(3b) represents a hydrogen atom, andR^(3c) represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₃₇₁).

A compound (L-30) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3b) represents a hydrogen atom, and R^(3c) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₃₇₂).

A compound (L-30) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₃₇₃).

A compound (L-30) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₃₇₄).

A compound (L-30) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₃₇₅).

A compound (L-30) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₃₇₆).

A compound (L-30) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₃₇₇).

A compound (L-30) wherein A¹ represents CH, R⁵ represents a methylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₃₇₈).

A compound (L-30) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₃₇₉).

A compound (L-30) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₃₈₀).

A compound (L-30) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₃₈₁).

A compound (L-30) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₃₈₂).

A compound (L-30) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₃₈₃).

A compound (L-30) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₃₈₄).

A compound represented by formula (L-31):

(hereinafter, referred to as Compound (L-31)) wherein A¹ represents CH,R⁵ represents a methyl group, R^(3b) represents a hydrogen atom, andR^(3c) represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₃₈₅).

A compound (L-31 wherein A¹ represents CH, R⁵ represents an ethyl group,R^(3b) represents a hydrogen atom, and R^(3c) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₃₈₆).

A compound (L-31) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₃₈₇).

A compound (L-31) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₃₈₈).

A compound (L-31) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₃₈₉).

A compound (L-31) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₃₉₀).

A compound (L-31) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₃₉₁).

A compound (L-31) wherein A¹ represents CH, R⁵ represents a methylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₃₉₂).

A compound (L-31) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₃₉₃).

A compound (L-31) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₃₉₄).

A compound (L-31) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₃₉₅).

A compound (L-31) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₃₉₆).

A compound (L-31) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₃₉₇).

A compound (L-31) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₃₉₈).

A compound represented by formula (L-32):

(hereinafter, referred to as Compound (L-32)) wherein A¹ represents CH,R⁵ represents a methyl group, R^(3b) represents a hydrogen atom, andR^(3c) represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₃₉₉).

A compound (L-32) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3b) represents a hydrogen atom, and R^(3c) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₄₀₀).

A compound (L-32) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₄₀₁).

A compound (L-32) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₄₀₂).

A compound (L-32) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₄₀₃).

A compound (L-32) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₄₀₄).

A compound (L-32) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₄₀₅).

A compound (L-32) wherein A¹ represents CH, R⁵ represents a methylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₄₀₆).

A compound (L-32) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₄₀₇).

A compound (L-32) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₄₀₈).

A compound (L-32) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₄₀₉).

A compound (L-32) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₄₁₀).

A compound (L-32) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₄₁₁).

A compound (L-32) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₄₁₂).

A compound represented by formula (L-33):

(hereinafter, referred to as Compound (L-33)) wherein A¹ represents CH,R⁵ represents a methyl group, R^(3b) represents a hydrogen atom, andR^(3c) represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₄₁₃).

A compound (L-33) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3b) represents a hydrogen atom, and R^(3c) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₄₁₄)

A compound (L-33) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₄₁₅).

A compound (L-33) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₄₁₆).

A compound (L-33) wherein A¹ represents a nitrogen atom, R⁵ representspropyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₄₁₇).

A compound (L-33) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₄₁₈).

A compound (L-33) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₁₁₉).

A compound (L-33) wherein A¹ represents CH, R⁵ represents a methylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₄₂₀).

A compound (L-33) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₄₂₁).

A compound (L-33) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₄₂₂).

A compound (L-33) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₄₂₃).

A compound (L-33) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₄₂₄).

A compound (L-33) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₄₂₅).

A compound (L-33) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₄₂₆).

A compound represented by formula (L-34):

(hereinafter, referred to as Compound (L-34)) wherein A¹ represents CH,R⁵ represents a methyl group, R^(3b) represents a hydrogen atom, andR^(3c) represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₄₂₇).

A compound (L-34) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3b) represents a hydrogen atom, and R^(3c) represents anysubstituents indicated in Table 7 to Table 1 (hereinafter, referred toas Compound Class SX₄₂₈).

A compound (L-34) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₄₂₉).

A compound (L-34) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₄₃₀).

A compound (L-34) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₄₃₁).

A compound (L-34) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₄₃₂).

A compound (L-34) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₄₃₃).

A compound (L-34) wherein A¹ represents CH, R⁵ represents a methylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₄₃₄).

A compound (L-34) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₄₃₅).

A compound (L-34) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₄₃₆).

A compound (L-34) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₄₃₇).

A compound (L-34) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₄₃₈).

A compound (L-34) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₄₃₉).

A compound (L-34) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₄₄₀).

A compound represented by formula (L-35):

(hereinafter, referred to as Compound (L-35)) wherein A¹ represents CH,R⁵ represents a methyl group, R^(3b) represents a hydrogen atom, andR^(3c) represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₄₄₁).

A compound (L-35) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3b) represents a hydrogen atom, and R^(3c) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₄₄₂).

A compound (L-35) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated it Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₄₄₃).

A compound (L-35) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₄₄₄).

A compound (L-35) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₄₄₅).

A compound (L-35) wherein A² represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₄₄₆).

A compound (L-35) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₄₄₇).

A compound (L-35) wherein A¹ represents CH, R⁵ represents a methylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₄₄₈).

A compound (L-35) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₄₄₉).

A compound (L-35) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₄₅₀).

A compound (L-35) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₄₅₁).

A compound (L-35) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₄₅₂).

A compound (L-35) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₄₅₃).

A compound (L-35) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₄₅₄).

A compound represented by formula (L-36):

(hereinafter, referred to as Compound (L-36)) wherein A¹ represents CH,R⁵ represents a methyl group, R^(3b) represents a hydrogen atom, andR^(3c) represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₄₅₅).

A compound (L-36) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3b) represents a hydrogen atom, and R^(3c) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₄₅₆).

A compound (L-36) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₄₅₇).

A compound (L-36) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₄₅₈).

A compound (L-36) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₄₅₉).

A compound (L-36) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₄₆₀).

A compound (L-36) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₄₆₁).

A compound (L-36) wherein A¹ represents CH, R⁵ represents a methylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₄₆₂).

A compound (L-36) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₄₆₃).

A compound (L-36) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated, in Table 7 to Table 15 (hereinafter,referred to as Compound Class SX₄₆₄).

A compound (L-36) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₄₆₅).

A compound (L-36) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₄₆₆).

A compound (L-36) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₄₆₇).

A compound (L-36) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₄₆₈).

A compound represented by formula (L-37):

(hereinafter, referred to as Compound (L-37)) wherein A¹ represents CH,R⁵ represents a methyl group, R^(3b) represents a hydrogen atom, andR^(3c) represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₄₆₉).

A compound (L-37) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3b) represents a hydrogen atom, and R^(3c) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₄₇₀).

A compound (L-37) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₄₇₁).

A compound (L-37) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₄₇₂).

A compound (L-37) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₄₇₃).

A compound (L-37) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₄₇₄).

A compound (L-37) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₄₇₅).

A compound (L 37) wherein A¹ represents CH, R⁵ represents a methylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₄₇₆).

A compound (L-37) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₄₇₇).

A compound (L-37) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₄₇₈).

A compound (L-37) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₄₇₉).

A compound (L-37) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₄₈₀).

A compound (L-37) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₄₈₁).

A compound (L-37) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₄₈₂).

A compound represented by formula (L-38):

(hereinafter, referred to as Compound (L-38)) wherein A¹ represents CH,R⁵ represents a methyl group, R^(3b) represents a hydrogen atom, andR^(3c) represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₄₈₃).

A compound (L-38) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3b) represents a hydrogen atom, and R^(3c) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₄₈₄).

A compound (L-38) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₄₈₅).

A compound (L-38) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₄₈₆).

A compound (L-38) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₄₈₇).

A compound (L-38) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₄₈₃).

A compound (L-38) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₄₈₉).

A compound (L-38) wherein A¹ represents CH, R⁵ represents a methylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₄₉₀).

A compound (L-38) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₄₉₁).

A compound (L-38) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₄₉₂).

A compound (L-38) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₄₉₃).

A compound (L-38) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₄₉₄).

A compound (L-38) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₄₉₅).

A compound (L-38) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₄₉₆).

A compound represented by formula (L-39):

(hereinafter, referred to as Compound (L-39)) wherein A¹ represents CH,R⁵ represents a methyl group, R^(3b) represents a hydrogen atom, andR^(3c) represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₄₉₇).

A compound (L-39) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3b) represents a hydrogen atom, and R^(3c) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₄₉₈).

A compound (L-39) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₄₉₉).

A compound (L-39) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₅₀₀).

A compound (L-39) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₅₀₁).

A compound (L-39) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₅₀₂).

A compound (L-39) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₅₀₃).

A compound (L-39) wherein A¹ represents CH, R⁵ represents a methylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₅₀₄).

A compound (L-39) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₅₀₅).

A compound (L-39) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₅₀₆).

A compound (L-39) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₅₀₇).

A compound (L-39) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₅₀₈).

A compound (L-39) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₅₀₉).

A compound (L-39) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₅₁₀).

A compound represented by formula (L-40):

(hereinafter, referred to as Compound (L-40)) wherein A¹ represents CH,R⁵ represents a methyl group, R^(3b) represents a hydrogen atom, andR^(3c) represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₅₁₁).

A compound (L-40) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3b) represents a hydrogen atom, and R^(3c) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₅₁₂).

A compound (L-40) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₅₁₃).

A compound (L-40) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₅₃₄).

A compound (L-40) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₅₁₅).

A compound (L-40) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₅₁₆).

A compound (L-40) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₅₁₇).

A compound (L-40) wherein A¹ represents CH, R⁵ represents a methylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₅₁₈).

A compound (L-40) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₅₁₉).

A compound (L-40) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₅₂₀).

A compound (L-40) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₅₂₁).

A compound (L-40) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₅₂₂).

A compound (L-40) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₅₂₃).

A compound (L-40) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₅₂₄).

A compound represented by formula (L-41):

(hereinafter, referred to as Compound (L-41)) wherein A¹ represents CH,R⁵ represents a methyl group, R^(3b) represents a hydrogen atom, andR^(3c) represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₅₂₅).

A compound (L-41) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3b) represents a hydrogen atom, and R^(3c) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₅₂₆).

A compound (L-41) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₅₂₇).

A compound (L-41) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₅₂₈).

A compound (L-41) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₅₂₉).

A compound (L-41) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₅₃₀).

A compound (L-41) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₅₃₁).

A compound (L-41) wherein A¹ represents CH, R⁵ represents a methylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₅₃₂).

A compound (L-41) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₅₃₃).

A compound (L-41) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₅₃₄).

A compound (L-41) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₅₃₅)

A compound (L-41) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₅₃₆).

A compound (L-41) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₅₃₇).

A compound (L-41) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₅₃₈).

A compound represented by formula (L-42):

(hereinafter, referred to as Compound (L-42)) wherein A¹ represents CH,R⁵ represents a methyl group, R^(3b) represents a hydrogen atom, andR^(3c) represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₅₃₉).

A compound (L-42) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3b) represents a hydrogen atom, and R^(3c) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₅₄₀).

A compound (L-42) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₅₄₁).

A compound (L-42) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₅₄₂).

A compound (L-42) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₅₄₃).

A compound (L-42) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₅₄₄).

A compound (L-42) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₅₄₅).

A compound (L-42) wherein A¹ represents CH, R⁵ represents a methylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₅₄₆).

A compound (L-42) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₅₄₇).

A compound (L-42) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₅₄₈).

A compound (L-42) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₅₄₉).

A compound (L-42) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₅₅₀).

A compound (L-42) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₅₅₁).

A compound (L-42) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₅₅₂).

A compound represented by formula (L-43):

(hereinafter, referred to as Compound (L-43)) wherein A¹ represents CH,R⁵ represents a methyl group, R^(3b) represents a hydrogen atom, andR^(3c) represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₅₅₃).

A compound (L-43) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3b) represents a hydrogen atom, and R^(3c) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₅₅₄).

A compound (L-43) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₅₅₅).

A compound (L-43) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₅₅₆).

A compound (L-43) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₅₅₇).

A compound (L-43) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₅₅₈).

A compound (L-43) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₅₅₉).

A compound (L-43) wherein A¹ represents CH, R⁵ represents a methylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₅₆₀).

A compound (L-43) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₅₆₁).

A compound (L-43) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₅₆₂).

A compound (L-43) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₅₆₃).

A compound (L-43) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₅₆₄).

A compound (L-43) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₅₆₅).

A compound (L-43) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₅₆₆).

A compound represented by formula (L-44):

(hereinafter, referred to as Compound (L-44)) wherein A¹ represents CH,R⁵ represents a methyl group, R^(3b) represents a hydrogen atom, andR^(3c) represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₅₆₇).

A compound (L-44) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3b) represents a hydrogen atom, and R^(3c) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₅₆₈).

A compound (L-44) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₅₆₉).

A compound (L-44) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₅₇₀).

A compound (L-44) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₅₇₁).

A compound (L-44) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₅₇₂).

A compound (L-44) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₅₇₃).

A compound (L-44) wherein A¹ represents CH, R⁵ represents a methylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₅₇₄).

A compound (L-44) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₅₇₅).

A compound (L-44) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₅₇₆).

A compound (L-44) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₅₇₇).

A compound (L-44) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₅₇₈).

A compound (L-44) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₅₇₉).

A compound (L-44) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₅₈₀).

A compound represented by formula (L-45):

(hereinafter, referred to as Compound (L-45)) wherein A¹ represents CH,R⁵ represents a methyl group, R^(3b) represents a hydrogen atom, andR^(3c) represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₅₈₁).

A compound (L-45) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3b) represents a hydrogen atom, and R^(3c) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₅₈₂).

A compound (L-45) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₅₈₃).

A compound (L-45) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₅₈₄).

A compound (L-45) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₅₈₅).

A compound (L-45) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₅₈₆).

A compound (L-45) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₅₈₇).

A compound (L-45) wherein A¹ represents CH, R⁵ represents a methylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₅₈₈).

A compound (L-45) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₅₈₉).

A compound (L-45) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₅₉₀).

A compound (L-45) wherein A¹ represents a nitrogen atom, R⁵ represents nethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₅₉₁).

A compound (L-45) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₅₉₂).

A compound (L-45) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3c) represent a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₅₉₃).

A compound (L-45) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₅₉₄).

A compound represented by formula (L-46):

(hereinafter, referred to as Compound (L-46)) wherein A¹ represents CH,R⁵ represents a methyl group, R^(3b) represents a hydrogen atom, andR^(3c) represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₅₉₅).

A compound (L-46) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3b) represents a hydrogen atom, and R^(3c) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₅₉₆).

A compound (L-46) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₅₉₇).

A compound (L-46) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₅₉₈).

A compound (L-46) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₅₉₉).

A compound (L-46) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₆₀₀).

A compound (L-46) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₆₀₁).

A compound (L-46) wherein A¹ represents CH, R⁵ represents a methylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₆₀₂).

A compound (L-46) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₆₀₃).

A compound (L-46) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₆₀₄).

A compound (L-46) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₆₀₅).

A compound (L-46) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₆₀₆).

A compound (L-46) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₆₀₇).

A compound (L-46) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₆₀₈).

A compound represented by formula (L-47):

(hereinafter, referred to as Compound (L-47)) wherein A¹ represents CH,R⁵ represents a methyl group, R^(3b) represents a hydrogen atom, andR^(3c) represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₆₀₉).

A compound (L-47) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3b) represents a hydrogen atom, and R^(3c) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₆₁₀).

A compound (L-47) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₆₁₁).

A compound (L-47) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₆₁₂).

A compound (L-47) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₆₁₃).

A compound (L-47) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₆₁₄).

A compound (L-47) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₆₁₅).

A compound (L-47) wherein A¹ represents CH, R⁵ represents a methylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₆₁₆).

A compound (L-47) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₆₁₇).

A compound (L-47) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₆₁₈).

A compound (L-47) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₆₁₉).

A compound (L-47) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₆₂₀).

A compound (L-47) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₆₂₁).

A compound (L-47) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₆₂₂).

A compound represented by formula (L-48):

(hereinafter, referred to as Compound (L-48)) wherein A¹ represents CH,R⁵ represents a methyl group, R^(3b) represents a hydrogen atom, andR^(3c) represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₆₂₃).

A compound (L-48) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3b) represents a hydrogen atom, and R^(3c) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₆₂₄).

A compound (L-48) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₆₂₅).

A compound (L-48) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₆₂₆).

A compound (L-48) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₆₂₇).

A compound (L-48) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₆₂₈).

A compound (L-48) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₆₂₉).

A compound (L-48) wherein A¹ represents CH, R⁵ represents a methylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₆₃₀).

A compound (L-48) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₆₃₁).

A compound (L-48) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₆₃₂).

A compound (L-48) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₆₃₃).

A compound (L-48) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₆₃₄).

A compound (L-48) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₆₃₅).

A compound (L-48) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₅₃₆).

A compound represented by formula (L-49):

(hereinafter, referred to as Compound (L-49)) wherein A¹ represents CH,R⁵ represents a methyl group, R^(3b) represents a hydrogen atom, andR^(3c) represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₆₃₇).

A compound (L-49) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3b) represents a hydrogen atom, and R^(3c) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₆₃₈).

A compound (L-49) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₆₃₉).

A compound (L-49) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₆₄₀).

A compound (L-49) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3b) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₆₄₁).

A compound (L-49) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₆₄₂).

A compound (L-49) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₆₄₃).

A compound (L-49) wherein A¹ represents CH, R⁵ represents a methylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₆₄₄).

A compound (L-49) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₆₄₅).

A compound (L-49) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₆₄₆).

A compound (L-49) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₆₄₇).

A compound (L-49) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₆₄₈).

A compound (L-49) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₆₄₉).

A compound (L-49) wherein represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₆₅₀).

A compound represented by formula (L-50):

(hereinafter, referred to as Compound (L-50)) wherein A¹ represents CH,R⁵ represents a methyl group, R^(3b) represents a hydrogen atom, andR^(3c) represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₆₅₁).

A compound (L-50) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3b) represents a hydrogen atom, and R^(3c) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₆₅₂).

A compound (L-50) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₆₅₃).

A compound (L-50) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3b) represents a hydrogen at and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₆₅₄).

A compound (L-50) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₆₅₅).

A compound L-50) wherein A¹ represents a nitrogen atom, R⁵ represents anisopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₆₅₆).

A compound (L-50) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₆₅₇).

A compound (L-50) wherein A¹ represents CH, R⁵ represents a methylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₆₅₈).

A compound (L-50) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₆₅₉).

A compound (L-50) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₆₆₀).

A compound (L-50) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₆₆₁).

A compound (L-50) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₆₆₂).

A compound (L-50) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₆₆₃).

A compound (L-50) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₆₆₄).

A compound represented by formula (L-51):

(hereinafter, referred to as Compound (L-51)) wherein A¹ represents CH,R⁵ represents a methyl group, R^(3b) represents a hydrogen atom, andR^(3c) represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₆₆₅).

A compound (L-51) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3b) represents a hydrogen atom, and R^(3c) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₆₆₆).

A compound (L-51) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₆₆₇).

A compound (L-51) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₆₆₉).

A compound (L-51) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₆₆₉).

A compound (L-51) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₆₇₀).

A compound (L-51) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₆₇₁).

A compound (L-51) wherein A¹ represents CH, R⁵ represents a methylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₆₇₂).

A compound (L-51) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₆₇₃).

A compound (L-51) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₆₇₄).

A compound (L-51) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₆₇₅).

A compound (L-51) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₆₇₆).

A compound (L-51) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₆₇₇).

A compound (L-51) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₆₇₈).

A compound represented by formula (L-52):

(hereinafter, referred to as Compound (L-52)) wherein A¹ represents CH,R⁵ represents a methyl group, R^(3b) represents a hydrogen atom, andR^(3c) represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₆₇₉).

A compound (L-52) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3b) represents a hydrogen atom, and R^(3c) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₆₈₀).

A compound (L-52) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₆₈₁).

A compound (L-52) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₆₈₂).

A compound (L-52) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₆₈₃).

A compound (L-52) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₆₈₄).

A compound (L-52) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₆₈₅).

A compound (L-52) wherein A¹ represents CH, R⁵ represents a methylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₆₈₆).

A compound (L-52) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₆₈₇).

A compound (L-52) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₆₈₈).

A compound (L-52) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₆₈₉).

A compound (L-52) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₆₉₀).

A compound (L-52) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₆₉₁).

A compound (L-52) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₆₉₂).

A compound represented by formula (L-53):

(hereinafter, referred to as Compound (L-53)) wherein A¹ represents CH,R⁵ represents a methyl group, R^(3b) represents a hydrogen atom, andR^(3c) represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₆₉₃).

A compound (L-53) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3b) represents a hydrogen atom, and R^(3c) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₆₉₄).

A compound (L-53) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₆₉₅).

A compound (L-53) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₆₉₆).

A compound (L-53) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 Table 15 (hereinafter, referred toas Compound Class SX₆₉₇).

A compound (L-53) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₆₉₈).

A compound (L-53) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₆₉₉).

A compound (L-53) wherein A¹ represents CH, R⁵ represents a methylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₇₀₀).

A compound (L-53) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₇₀₁).

A compound (L-53) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₇₀₂).

A compound (L-53) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₇₀₃).

A compound (L-53) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₇₀₄).

A compound (L-53) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₇₀₅).

A compound (L-53) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₇₀₆).

A compound represented by formula (L-54):

(hereinafter, referred to as Compound (L-54)) wherein A¹ represents CH,R⁵ represents a methyl group, R^(3b) represents a hydrogen atom, andR^(3c) represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₇₀₇).

A compound (L-54) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3b) represents a hydrogen atom, and R^(3c) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₇₀₈).

A compound (L-54) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₇₀₉).

A compound (L-54) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₇₁₀).

A compound (L-54) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₇₁₁).

A compound (L-54) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₇₁₂).

A compound (L-54) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₇₁₃).

A compound (L-54) wherein A¹ represents CH, R⁵ represents a methylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₇₁₄).

A compound (L-54) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₇₁₅).

A compound (L-54) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₇₁₆).

A compound (L-54) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₇₁₇).

A compound (L-54) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₇₁₈).

A compound (L-54) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₇₁₉).

A compound (L-54) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₇₂₀).

A compound represented by formula (L-55):

(hereinafter, referred to as Compound (L-55)) wherein A¹ represents CH,R⁵ represents a methyl group, R^(3b) represents a hydrogen atom, andR^(3c) represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₇₂₁).

A compound (L-55) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3b) represents a hydrogen atom, and R^(3c) represents nsubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₇₂₂).

A compound (L-55) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₇₂₃).

A compound (L-55) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₇₂₄).

A compound (L-55) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₇₂₅).

A compound (L-55) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₇₂₆).

A compound (L-55) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₇₂₇).

A compound (L-55) wherein A¹ represents CH, R⁵ represents a methylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₇₂₈).

A compound (L-55) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₇₂₉).

A compound (L-55) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₇₃₀).

A compound (L-55) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₇₃₁).

A compound (L-55) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₇₃₂).

A compound (L-55) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₇₃₃).

A compound (L-55) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₇₃₄).

A compound represented by formula (L-56):

(hereinafter, referred to as Compound (L-56)) wherein A¹ represents CH,R⁵ represents a methyl group, R^(3b) represents a hydrogen atom, andR^(3c) represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₇₃₅).

A compound (L-56) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3b) represents a hydrogen atom, and R^(3c) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₇₃₆).

A compound (L-56) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₇₃₇).

A compound (L-56) wherein A² represents a nitrogen atom, R⁵ representsan ethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₇₃₈).

A compound (L-56) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₇₃₉).

A compound (L-56) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₇₄₀).

A compound (L-56) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₇₄₁).

A compound (L-56) wherein A¹ represents CH, R⁵ represents a methylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₇₄₂).

A compound (L-56) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₇₄₃).

A compound (L-56) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₇₄₄).

A compound (L-56) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₇₄₅).

A compound (L-56) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₇₄₆).

A compound (L-56) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₇₄₇).

A compound (L-56) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₇₄₈).

A compound represented by formula (L-57):

(hereinafter, referred to as Compound (L-57)) wherein A¹ represents CH,R⁵ represents a methyl group, R^(3b) represents a hydrogen atom, andR^(3c) represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₇₄₉).

A compound (L-57) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3b) represents a hydrogen atom, and R^(3c) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₇₅₀).

A compound (L-57) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₇₅₁).

A compound (L-57) wherein A¹ presents a nitrogen atom, R⁵ represents anethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₇₅₂).

A compound (L-57) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₇₅₃).

A compound (L-57) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₂₅₄).

A compound (L-57) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₇₅₅).

A compound (L-57) wherein A¹ represents CH, R⁵ represents a methylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₇₅₆).

A compound (L-57) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₇₅₇).

A compound (L-57) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₇₅₈).

A compound (L-57) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₇₅₉).

A compound (L-57) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₇₆₀).

A compound (L-57) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₇₆₁).

A compound (L-57) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₇₆₂).

A compound represented by formula (L-58):

(hereinafter, referred to as Compound (L-58)) wherein A¹ represents CH,R⁵ represents a methyl group, R^(3b) represents a hydrogen atom, andR^(3c) represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₇₆₃).

A compound (L-58) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3b) represents a hydrogen atom, and R^(3c) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₇₆₄).

A compound (L-58) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₇₆₅).

A compound (L-58) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₇₆₆).

A compound (L-58) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₇₆₇).

A compound (L-58) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₇₆₈).

A compound (L-58) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₇₆₉).

A compound (L-58) wherein A¹ represents CH, R⁵ represents a methylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₇₇₀).

A compound (L-58) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₇₇₁).

A compound (L-58) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₇₇₂).

A compound (L-58) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₇₇₃).

A compound (L-56) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₇₇₄).

A compound (L-56) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₇₇₅).

A compound (L-58) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₇₇₆).

A compound represented by formula (L-59):

(hereinafter, referred to as Compound (L-59)) wherein A¹ represents CH,R⁵ represents a methyl group, R^(3b) represents a hydrogen atom, andR^(3c) represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₇₇₇).

A compound (L-59) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3b) represents a hydrogen atom, and R^(3c) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₇₇₈).

A compound (L-59) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₇₇₉).

A compound (L-59) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₇₈₀).

A compound (L-59) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₇₈₁).

A compound (L-59) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₇₈₂).

A compound (L-59) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₇₈₃).

A compound (L-59) wherein A¹ represents CH, R⁵ represents a methylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₇₈₄).

A compound (L-59) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₇₈₅).

A compound (L-59) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₇₈₆).

A compound (L-59) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₇₈₇).

A compound (L-59) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₇₈₈).

A compound (L-59) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₇₈₉).

A compound (L-59) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₇₉₀).

A compound represented by formula (L-60):

(hereinafter, referred to as Compound (L-60)) wherein A¹ represents CH,R⁵ represents a methyl group, R^(3b) represents a hydrogen atom, andR^(3c) represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₇₉₁).

A compound (L-60) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3b) represents a hydrogen atom, and R^(3c) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₇₉₂).

A compound (L-60) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₇₉₃).

A compound (L-60) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₇₉₄).

A compound (L-60) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₇₉₅).

A compound (L-60) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₇₉₆).

A compound (L-60) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₇₉₇).

A compound (L-60) wherein A¹ represents CH, R⁵ represents a methylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₇₉₈).

A compound (L-60) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₇₉₉).

A compound (L-60) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₈₀₀).

A compound (L-60) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₈₀₁).

A compound (L-60) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₈₀₂).

A compound (L-60) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₈₀₃).

A compound (L-60) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₈₀₄).

A compound represented by formula (L-61):

(hereinafter, referred to as Compound (L-61)) wherein A¹ represents CH,R⁵ represents a methyl group, R^(3b) represents a hydrogen atom, andR^(3c) represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₈₀₅).

A compound (L-61) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3b) represents a hydrogen atom, and R^(3c) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₈₀₆).

A compound (L-61) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₈₀₇).

A compound (L-61) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₈₀₈).

A compound (L-61) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₈₀₉).

A compound (L-61) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₈₁₀).

A compound (L-61) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₈₁₁).

A compound (L-61) wherein A¹ represents CH, R⁵ represents a methylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₈₁₂).

A compound (L-61) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₈₁₃).

A compound (L-61) wherein A¹ represents a nitrogen atom, R⁵ representsmethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₈₁₄).

A compound (L-61) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₈₁₅).

A compound (L-61) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₈₁₆).

A compound (L-61) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₈₁₇).

A compound (L-61) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₈₁₈).

A compound represented by formula (62):

(hereinafter, referred to as Compound (L-62)) wherein A¹ represents CH,R⁵ represents a methyl group, R^(3b) represents a hydrogen atom, andR^(3c) represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₈₁₉).

A compound (L-62) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3b) represents a hydrogen atom, and R^(3c) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₈₂₀).

A compound (L-62) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₈₂₁).

A compound (L-62) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₈₂₂).

A compound (L-62) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₈₂₃).

A compound (L-62) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₈₂₄).

A compound (L-62) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₈₂₅).

A compound (L-62) wherein A¹ represents CH, R⁵ represents a methylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₈₂₆).

A compound (L-62) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₈₂₇).

A compound (L-62) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₈₂₈).

A compound (L-62) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₈₂₉).

A compound (L-62) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₈₃₀).

A compound (L-62) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₈₃₁).

A compound (L-62) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₈₃₂).

A compound represented by formula (L-63):

(hereinafter, referred to as Compound (L-63)) wherein A¹ represents CH,R⁵ represents a methyl group, R^(3b) represents a hydrogen atom, andR^(3c) represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₈₃₃).

A compound (L-63) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3b) represents a hydrogen atom, and R^(3c) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₈₃₄).

A compound (L-63) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₈₃₅).

A compound (L-63) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₈₃₆).

A compound (L-63) wherein A¹ represents a nitrogen atom, P⁵ represents apropyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₈₃₇).

A compound (L-63) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, refer to as Compound Class SX₈₃₈).

A compound (L-63) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₈₃₉).

A compound (L-63) wherein A¹ represents CH, R⁵ represents a methylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₈₄₀).

A compound (L-63) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₈₄₁).

A compound (L-63) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₈₄₂).

A compound (L-63) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₈₄₃).

A compound (L-63) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₈₄₄).

A compound (L-63) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₈₄₅).

A compound (L-63) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₈₄₆).

A compound represented by formula (L-64):

(hereinafter, referred to as Compound (L-64)) wherein A¹ represents CH,R⁵ represents a methyl group, R^(3b) represents a hydrogen atom, andR^(3c) represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₈₄₇).

A compound (L-64) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3b) represents a hydrogen atom, and R^(3c) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₈₄₈).

A compound (L-64) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₈₄₉).

A compound (L-64) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₈₅₀).

A compound (L-64) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₈₅₁).

A compound (L-64) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₈₅₂).

A compound (L-64) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₈₅₃).

A compound (L-64) wherein A¹ represents CH, R⁵ represents a methylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₈₅₄).

A compound (L-64) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₈₅₅).

A compound (L-64) wherein A¹ represents a nitrogen atom, represents amethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₈₅₆).

A compound (L-64) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₈₅₇).

A compound (L-64) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₈₅₅).

A compound (L-64) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₈₅₉).

A compound (L-64) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₈₆₀).

A compound represented by formula (L-65):

(hereinafter, referred to as Compound (L-65)) wherein A¹ represents CH,R⁵ represents a methyl group, R^(3b) represents a hydrogen atom, andR^(3c) represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₈₆₁).

A compound (L-65) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3b) represents a hydrogen atom, and R^(3c) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₈₆₂).

A compound (L-65) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₈₆₃).

A compound (L-65) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₈₆₄).

A compound (L-65) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₈₆₅).

A compound (L-65) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₈₆₆).

A compound (L-65) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₈₆₇).

A compound (L-65) wherein A¹ represents CH, R⁵ represents a methylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₈₆₈).

A compound (L-65) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₈₆₉).

A compound (L-65) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₈₇₀).

A compound (L-65) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₈₇₁).

A compound (L-65) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₈₇₂).

A compound (L-65) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₈₇₃).

A compound (L-65) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₈₇₄).

A compound represented by formula (L-66):

(hereinafter, referred to as Compound (L-66)) wherein A¹ represents CH,R⁵ represents a methyl group, R^(3b) represents a hydrogen atom, andR^(3c) represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₈₇₅).

A compound (L-66) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3b) represents a hydrogen atom, and R^(3c) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₈₇₆).

A compound (L-66) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₈₇₇).

A compound (L-66) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₈₇₈).

A compound (L-66) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₈₇₉).

A compound (L-66) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₈₈₀).

A compound (L-66) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₈₈₁).

A compound (L-66) wherein A¹ represents CH, R⁵ represents a methylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₈₈₂).

A compound (L-66) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₈₈₃).

A compound (L-66) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₈₈₄).

A compound (L-66) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₈₈₅).

A compound (L-66) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₈₈₆).

A compound (L-66) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₈₈₇).

A compound (L-66) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₈₈₈).

A compound represented by formula (L-67):

(hereinafter, referred to as Compound (L-67)) wherein A¹ represents CH,R⁵ represents a methyl group, R^(3b) represents a hydrogen atom, andR^(3c) represents any substituents indicated in Table 7 to Table 15thereinafter, referred to as Compound Class SX₈₈₉).

A compound (L-67) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3b) represents a hydrogen atom, and R^(3c) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₈₉₀).

A compound (L-67) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₈₉₁).

A compound (L-67) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₈₉₂).

A compound (L-67) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₈₉₃).

A compound (L-67) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₈₉₄).

A compound (L-67) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₈₉₅).

A compound (L-67) wherein A¹ represents CH, R⁵ represents a methylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₈₉₆).

A compound (L-67) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₈₉₇).

A compound (L-67) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₈₉₈).

A compound (L-67) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3c) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₈₉₉).

A compound (L-67) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₉₀₀).

A compound (L-67) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₉₀₁).

A compound (L-67) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₉₀₂).

A compound represented by formula (L-68):

(hereinafter, referred to as Compound (L-68)) wherein A¹ represents CH,R⁵ represents a methyl group, R^(3b) represents a hydrogen atom, andR^(3c) represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₉₀₃).

A compound (L-68) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3b) represents a hydrogen atom, and R^(3c) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₉₀₄).

A compound (L-68) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₉₀₅).

A compound (L-68) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₉₀₆).

A compound (L-68) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₉₀₇).

A compound (L-69) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₉₀₈).

A compound (L-68) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₉₀₉).

A compound (L-68) wherein A¹ represents CH, R⁵ represents a methylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₉₁₀).

A compound (L-68) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₉₁₁).

A compound (L-68) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₉₁₂).

A compound (L-68) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₉₁₃).

A compound (L-68) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₉₁₄).

A compound (L-68) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₉₁₅).

A compound (L-68) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₉₁₆).

A compound represented by formula (L-69):

(hereinafter, referred to as Compound (L-69)) wherein A¹ represents CH,R⁵ represents a methyl group, R^(3b) represents a hydrogen atom, andR^(3c) represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₉₁₇).

A compound (L-69) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3b) represents a hydrogen atom, and R^(3c) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₉₁₈).

A compound (L-69) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₉₁₉).

A compound (L-69) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₉₂₀).

A compound (L-69) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₉₂₁).

A compound (L-69) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₉₂₂).

A compound (L-69) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₉₂₃).

A compound (L-69) wherein A¹ represents CH, R⁵ represents a methylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₉₂₄).

A compound (L-69) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₉₂₅).

A compound (L-69) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₉₂₆).

A compound (L-69) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₉₂₇).

A compound (L-69) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₉₂₈).

A compound (L-69) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₉₂₉).

A compound (L-69) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₉₃₀).

A compound represented by formula L-70):

(hereinafter, referred to as Compound L-7.0)) wherein A¹ represents CH,R⁵ represents a methyl group, R^(3b) represents hydrogen atom, andR^(3c) represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₉₃₁).

A compound (L-70) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3b) represents a hydrogen atom, and R^(3c) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₉₃₂).

A compound (L-70) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₉₃₃).

A compound (L-70) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₉₃₄).

A compound (L-70) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, R^(3b) represents a hydrogen atom, and R^(3c) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₉₃₅).

A compound (L-70) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₉₃₆).

A compound (L-70) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3b) represents a hydrogen atom, and R^(3c)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₉₃₇).

A compound (L-70) wherein A¹ represents CH, R⁵ represents a methylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₉₃₈).

A compound (L-70) wherein A¹ represents CH, R⁵ represents an ethylgroup, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₉₃₉).

A compound (L-70) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₉₄₀).

A compound (L-70) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, R^(3c) represents a hydrogen atom, and R^(3b) representssubstituents indicated in Table 7 to Table 15 (hereinafter, referred toas Compound Class SX₉₄₁).

A compound (L-70) wherein A¹ represents a nitrogen atom, represents apropyl group, R^(3c) represents a hydrogen atom, and R^(3b) representsany substituents indicated in Table 7 to Table 15 (hereinafter, referredto as Compound Class SX₉₄₂).

A compound (L-70) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₉₄₃).

A compound (L-70) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15(hereinafter, referred to as Compound Class SX₉₄₄).

A compound represented by formula (L-71):

(hereinafter, referred to as Compound (L-71)) wherein A¹ represents CH,R⁵ represents a methyl group, and T represents any substituentsindicated in Table 1 to Table 6 (hereinafter, referred to as CompoundClass SX₉₄₅).

A compound (L-71) wherein A¹ represents CH, R⁵ represents an ethylgroup, and T represents any substituents indicated in Table 1 to Table 6(hereinafter, referred to as Compound Class SX₉₄₆).

A compound (L-71) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, and T represents any substituents indicated in Table 1 toTable 6 (hereinafter, referred to as Compound Class SX₉₄₇).

A compound (L-71) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, and T represents any substituents indicated in Table 1to Table 6 (hereinafter, referred to as Compound Class SX₉₄₈).

A compound (L-71) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, and T represents any substituents indicated in Table 1 toTable 6 (hereinafter, referred to as Compound Class SX₉₄₉).

A compound (L-71) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, and T represents any substituents indicated in Table1 to Table 6 (hereinafter, referred to as Compound Class SX₉₅₀).

A compound (L-71) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, and T represents any substituents indicated in Table1 to Table 6 (hereinafter, referred to as Compound Class SX₉₅₁).

A compound represented by formula (L-72):

(hereinafter, referred to as Compound (L-72)) wherein A¹ represents CH,R⁵ represents a methyl group, and T represents any substituentsindicated in Table 1 to Table 6 (hereinafter, referred to as CompoundClass SX₉₅₂).

A compound (L-72) wherein A¹ represents CH, R⁵ represents an ethylgroup, and T represents any substituents indicated in Table 1 to Table 6(hereinafter, referred to as Compound Class SX₉₅₃).

A compound (L-72) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, and T represents any substituents indicated in Table 1 toTable 6 (hereinafter, referred to as Compound Class SX₉₅₄).

A compound (L-72) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, and T represents any substituents indicated in Table 1to Table 6 (hereinafter, referred to as Compound Class SX₉₅₅).

A compound (L-72) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, and T represents any substituents indicated in Table 1 toTable 6 (hereinafter, referred to as Compound Class SX₉₅₆).

A compound (L-72) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, and T represents any substituents indicated in Table1 to Table 6 (hereinafter, referred to as Compound Class SX₉₅₇).

A compound L-72) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, and T represents any substituents indicated in Table1 to Table 6 (hereinafter, referred to as Compound Class SX₉₅₈).

A compound represented by formula (L-73):

(hereinafter, referred to as Compound (L-73)) wherein A¹ represents CH,R⁵ represents a methyl group, and T represents any substituentsindicated in Table 1 to Table 6 (hereinafter, referred to as CompoundClass SX₉₅₉).

A compound (L-73) wherein A¹ represents CH, R⁵ represents an ethylgroup, and T represents any substituents indicated in Table 1 to Table 6(hereinafter, referred to as Compound Class SX₉₆₀).

A compound (L-73) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, and T represents any substituents indicated in Table 1 toTable 6 (hereinafter, referred to as Compound Class SX₉₆₁).

A compound (L-73) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, and T represents any substituents indicated in Table 1to Table 6 (hereinafter, referred to as Compound Class SX₉₆₂).

A compound (L-73) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, and T represents any substituents indicated in Table 1 toTable 6 (hereinafter, referred to as Compound Class SX₉₆₃).

A compound (L-73) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, and T represents any substituents indicated in Table1 to Table 6 (hereinafter, referred to as Compound Class SX₉₆₄).

A compound (L-73) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, and T represents any substituents indicated in Table1 to Table 6 (hereinafter, referred to as Compound Class SX₉₆₅).

A compound represented by formula (L-74):

(hereinafter, referred to as Compound (L-74)) wherein A¹ represents CH,R⁵ represents a methyl group, and T represents any substituentsindicated in Table 1 to Table 6 (hereinafter, referred to as CompoundClass SX₉₆₆).

A compound (L-74) wherein A¹ represents CH, R⁵ represents an ethylgroup, and T represents any substituents indicated in Table 1 to Table 6(hereinafter, referred to as compound Class SX₉₆₇).

A compound (L-74) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, and T represents any substituents indicated in Table 1 toTable 6 (hereinafter, referred to as Compound Class SX₉₆₈).

A compound (L-74) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, and T represents any substituents indicated in Table 1to Table 6 (hereinafter, referred to as Compound Class SX₉₆₉).

A compound (L-74) wherein A¹ represents a nitrogen atom, R⁵ representspropyl group, and T represents any substituents indicated in Table 1 toTable 6 (hereinafter, referred to as Compound Class SX₉₇₀).

A compound (L-74) wherein A¹ represents a nitrogen atom, R¹ representsan isopropyl group, and T represents any substituents indicated in Table1 to Table 6 (hereinafter, referred to as Compound Class SX₉₇₁).

A compound (L-74) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, and T represents any substituents indicated in Table1 to Table 6 (hereinafter, referred to as Compound Class SX₉₇₂).

A compound represented by formula (L-75):

(hereinafter, referred to Compound (L-75)) wherein A¹ represents CH, R⁵represents a methyl group, and T represents any substituents indicatedin Table 1 to Table 6 (hereinafter, referred to as Compound ClassSX₉₇₃).

A compound (L-75) wherein A¹ represents CH, R⁵ represents an ethylgroup, and T represents any substituents indicated in Table 1 to Table 6(hereinafter, referred to as Compound Class SX₉₇₄).

A compound (L-75) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, and T represents any substituents indicated in Table 1 toTable 6 (hereinafter, referred to as Compound Class SX₉₇₅).

A compound (L-75) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, and T represents any substituents indicated in Table 1to Table 6 (hereinafter, referred to as Compound Class SX₉₇₆).

A compound (L-75) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, and T represents any substituents indicated in Table 1 toTable 6 (hereinafter, referred to as Compound Class SX₉₇₇).

A compound (L-75) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, and T represents any substituents indicated in Table1 to Table 6 (hereinafter, referred to as Compound Class SX₉₇₈).

A compound (L-75) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, and T represents any substituents indicated in Table1 to Table 6 (hereinafter, referred to as Compound Class SX₉₇₉).

A compound represented by formula (L-76):

(hereinafter, referred to as Compound (L-76)) wherein A¹ represents CH,R⁵ represents a methyl group, and T represents any substituentsindicated in Table 1 to Table 6 (hereinafter, referred to as CompoundClass SX₉₈₀).

A compound (L-76) wherein A¹ represents CH, R⁵ represents an ethylgroup, and T represents any substituents indicated in Table 1 to Table 6(hereinafter, referred to as Compound Class SX₉₈₁).

A compound (L-76) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, and T represents any substituents indicated in Table 1 toTable 6 (hereinafter, referred to as Compound Class SX₉₈₂).

A compound (L-76) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, and T represents any substituents indicated in Table 1to Table 6 (hereinafter, referred to as Compound Class SX₉₈₃).

A compound (L-76) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, and T represents any substituents indicated in Table 1 toTable 6 (hereinafter, referred to as Compound Class SX₉₈₄).

A compound (L-76) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, and T represents any substituents indicated in Table1 to Table 6 (hereinafter, referred to as Compound Class SX₉₈₅).

A compound (L-76) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, and T represents any substituents indicated in Table1 to Table 6 (hereinafter, referred to as Compound Class SX₉₈₆).

A compound represented by formula (L-77):

(hereinafter, referred to as Compound (L-77)) wherein A¹ represents CH,R⁵ represents a methyl group, and T represents any substituentsindicated in Table 1 to Table 6 (hereinafter, referred to as CompoundClass SX₉₈₇).

A compound (L-77) wherein A¹ represents CH, R⁵ represents an ethylgroup, and T represents any substituents indicated in Table 1 to Table 6(hereinafter, referred to as Compound Class SX₉₈₈).

A compound (L-77) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, and T represents any substituents indicated in Table 1 toTable 6 (hereinafter, referred to as Compound Class SX₉₈₉).

A compound (L-77) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, and T represents any substituents indicated in Table 1to Table 6 (hereinafter, referred to as Compound Class SX₉₉₀).

A compound (L-77) wherein A¹ represents a nitrogen atom, R⁵ representspropyl group, and T represents any substituents indicated in Table 1 toTable 6 (hereinafter, referred to as Compound Class SX₉₉₁).

A compound (L-77) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, and T represents any substituents indicated in Table1 to Table 6 (hereinafter, referred to as Compound Class SX₉₉₂).

A compound (L-77) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, and T represents any substituents indicated in Table1 to Table 6 (hereinafter, referred to as Compound Class SX₉₉₃).

A compound represented by formula (L-78):

(hereinafter, referred to as Compound (L-78)) wherein A¹ represents CH,R⁵ represents a methyl group, and T represents any substituentsindicated in Table 1 to Table 6 (hereinafter, referred to as CompoundClass SX₉₉₄).

A compound (L-78) wherein A¹ represents CH, R⁵ represents an ethylgroup, and T represents any substituents indicated in Table 1 to Table 6(hereinafter, referred to as Compound Class SX₉₉₅).

A compound (L-78) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, and T represents any substituents indicated in Table 1 toTable 6 (hereinafter, referred to as Compound Class SX₉₉₆).

A compound (L-78) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, and T represents any substituents indicated in Table 1to Table 6 (hereinafter, referred to as Compound Class SX₉₉₇).

A compound (L-78) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, and b represents any substituents indicated in Table 1 toTable 6 (hereinafter, referred to as Compound Class SX₉₉₈).

A compound (L-78) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, and T represents any substituents indicated in Table1 to Table 6 (hereinafter, referred to as Compound Class SX₉₉₉).

A compound (L-78) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, and T represents any substituents indicated in Table1 to Table 6 (hereinafter, referred to as Compound Class SX₁₀₀₀).

A compound represented by formula (L-79):

(hereinafter, referred to as Compound (L-79)) wherein A¹ represents CH,R⁵ represents a methyl group, and T represents any substituentsindicated in Table 1 to Table 6 (hereinafter, referred to as CompoundClass SX₁₀₀₁).

A compound (L-79) wherein A¹ represents CH, R⁵ represents an ethylgroup, and T represents any substituents indicated in Table 1 to Table 6(hereinafter, referred to as Compound Class SX₁₀₀₂).

A compound (L-79) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, and T represents any substituents indicated in Table 1 toTable 6 (hereinafter, referred to as Compound Class SX₁₀₀₃).

A compound (L-79) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, and T represents any substituents indicated in Table 1to Table 6 (hereinafter, referred to as Compound Class SX₁₀₀₄).

A compound (L-79) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, and T represents any substituents indicated in Table 1 toTable 6 (hereinafter, referred to as Compound Class SX₁₀₀₅).

A compound (L-79) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, and T represents any substituents indicated in Table1 to Table 6 (hereinafter, referred to as Compound Class SX₁₀₀₆).

A compound (L-79) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, and T represents any substituents indicated in Table1 to Table 6 (hereinafter, referred to as Compound Class SX₁₀₀₇).

A compound represented by formula (L-80):

(hereinafter, referred to as Compound (L-80)) wherein A¹ represents CH,R⁵ represents a methyl group, and T represents any substituentsindicated in Table 1 to Table 6 (hereinafter, referred to as CompoundClass SX₁₀₀₈).

A compound (L-80) wherein A¹ represents CH, R⁵ represents an ethylgroup, and T represents any substituents indicated in Table 1 to Table 6(hereinafter, referred to as Compound Class SX₁₀₀₉).

A compound (L-80) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, and T represents any substituents indicated in Table 1 toTable 6 (hereinafter, referred to as Compound Class SX₁₀₁₀).

A compound (L-80) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, and T represents any substituents indicated in Table 1to Table 6 (hereinafter, referred to as Compound Class SX₁₀₁₁).

A compound (L-80) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, and T represents any substituents indicated in Table 1 toTable 6 (hereinafter, referred to as Compound Class SX₁₀₁₂).

A compound (L-80) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, and T represents any substituents indicated in Table1 to Table 6 (hereinafter, referred to as Compound Class SX₁₀₁₃).

A compound (L-80) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, and T represents any substituents indicated in Table1 to Table 6 (hereinafter, referred to as Compound Class SX₁₀₁₄).

A compound (L-1) wherein A¹ represents a nitrogen atom, R⁴ represents amethyl group, R⁵ represents a methyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₁₀₁₅).

A compound (L-1) wherein A¹ represents a nitrogen atom, R⁴ represents amethyl group, R⁵ represents an ethyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₁₀₁₆).

A compound (L-1) wherein A¹ represents a nitrogen atom, R⁴ represents amethyl group, R⁵ represents a propyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₁₀₁₇).

A compound (L-1) wherein A¹ represents a nitrogen atom, R⁴ represents amethyl group, R⁵ represents an isopropyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₁₀₁₈).

A compound (L-1) wherein A¹ represents a nitrogen atom, R⁴ represents amethyl group, R⁵ represents a cyclopropyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₁₀₁₉).

A compound (L-3) wherein A¹ represents a nitrogen atom, R⁴ represents amethyl group, R⁵ represents a methyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₁₀₂₀).

A compound (L-3) wherein A¹ represents a nitrogen atom, R⁴ represents amethyl group, R⁵ represents an ethyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₁₀₂₁).

A compound (L-3) wherein A¹ represents a nitrogen atom, R⁴ represents amethyl group, R⁵ represents a propyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₁₀₂₂).

A compound (L-3) wherein A¹ represents a nitrogen atom, R⁴ represents amethyl group, R⁵ represents an isopropyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₁₀₂₃).

A compound (L-3) wherein A¹ represents a nitrogen atom, R⁴ represents amethyl group, R⁵ represents a cyclopropyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₁₀₂₄).

A compound (L-5) wherein A¹ represents a nitrogen atom, R⁴ represents amethyl group, R⁵ represents a methyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₁₀₂₅).

A compound (L-5) wherein A¹ represents a nitrogen atom, R⁴ represents amethyl group, R⁵ represents an ethyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₁₀₂₆).

A compound (L-5) wherein A¹ represents a nitrogen atom, R⁴ represents amethyl group, R⁵ represents a propyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₁₀₂₇).

A compound (L-5) wherein A¹ represents a nitrogen atom, R⁴ represents amethyl group, R⁵ represents an isopropyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₁₀₂₈).

A compound (L-5) wherein A¹ represents a nitrogen atom, represents amethyl group, R⁵ represents a cyclopropyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₁₀₂₉).

A compound (L-7) wherein A¹ represents a nitrogen atom, R⁴ represents amethyl group, R⁵ represents a methyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₁₀₃₀).

A compound (L-7) wherein A¹ represents a nitrogen atom, R⁴ represents amethyl group, R⁵ represents an ethyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₁₀₃₁).

A compound (L-7) wherein A¹ represents a nitrogen atom, R⁴ represents amethyl group, R⁵ represents a propyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₁₀₃₂).

A compound (L-7) wherein A¹ represents a nitrogen atom, R⁴ represents amethyl group, R⁵ represents an isopropyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₁₀₃₃).

A compound (L-7) wherein A¹ represents a nitrogen atom, R⁴ represents amethyl group, R⁵ represents an cyclopropyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₁₀₃₄).

A compound represented by formula (L-81):

(hereinafter, referred to as Compound (L-81)) wherein A¹ represents CH,R⁴ represents a hydrogen atom, R⁵ represents a methyl group, and Trepresents any substituents indicated in Table 1 to Table 6(hereinafter, referred to as Compound Class SX₁₀₃₅).

A compound (L-81) wherein A¹ represents CH, R⁴ represents a hydrogenatom, R⁵ represents an ethyl group, and T represents any substituentsindicated in Table 1 to Table 6 (hereinafter, referred to as CompoundClass SX₁₀₃₆).

A compound (L-81) wherein A¹ represents a nitrogen atom, R⁴ represents ahydrogen atom, R⁵ represents a methyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₁₀₃₇).

A compound (L-81) wherein A¹ represents a nitrogen atom, R⁴ represents ahydrogen atom, R⁵ represents an ethyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₁₀₃₈).

A compound (L-81) wherein A¹ represents a nitrogen atom, R⁴ represents ahydrogen atom, R⁵ represents a propyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₁₀₃₉).

A compound (L-81) wherein A¹ represents a nitrogen atom, R⁴ represents ahydrogen atom, R⁵ represents an isopropyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₁₀₄₀).

A compound (L-81) wherein A¹ represents a nitrogen atom, R⁴ represents ahydrogen atom, R⁵ represents a cyclopropyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₁₀₄₁).

A compound (L-81) wherein A¹ represents a nitrogen atom, R⁴ represents achlorine atom, R⁵ represents a methyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₁₀₄₂).

A compound (L-81) wherein A¹ represents a nitrogen atom, R⁴ represents achlorine atom, R⁵ represents an ethyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₁₀₄₃).

A compound (L-81) wherein A¹ represents a nitrogen atom, R⁴ represents achlorine atom, R⁵ represents a propyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₁₀₄₄).

A compound (L-81) wherein A¹ represents a nitrogen atom, R⁴ represents achlorine atom, R⁵ represents an isopropyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₁₀₄₅).

A compound (L-81) wherein A¹ represents a nitrogen atom, R⁴ represents achlorine atom, R⁵ represents a cyclopropyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₁₀₄₆).

A compound (L-81) wherein A¹ represents a nitrogen atom, R⁴ represents amethyl group, R⁵ represents a methyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₁₀₄₇).

A compound (L-81) wherein A¹ represents a nitrogen atom, R⁴ represents amethyl group, R⁵ represents an ethyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₁₀₄₈).

A compound (L-81) wherein A¹ represents a nitrogen atom, R⁴ represents amethyl group, R⁵ represents a propyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₁₀₄₉).

A compound (L-81) wherein A¹ represents a nitrogen atom, R⁴ represents amethyl group, R⁵ represents an isopropyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₁₀₅₀).

A compound (L-81) wherein A¹ represents a nitrogen atom, R⁴ represents amethyl group, R⁵ represents a cyclopropyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₁₀₅₁).

A compound represented by formula (L-82):

(hereinafter, referred to as Compound (L-82)) wherein A¹ represents CH,R⁵ represents a methyl group, and T represents any substituentsindicated in Table 1 to Table 6 (hereinafter, referred to as CompoundClass SX₁₀₅₂).

A compound (L-82) wherein A¹ represents CH, R⁵ represents an ethylgroup, and T represents any substituents indicated in Table 1 to Table 6(hereinafter, referred to as Compound Class SX₁₀₅₃).

A compound (L-82) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, and T represents any substituents indicated in Table 1 toTable 6 (hereinafter, referred to as Compound Class SX₁₀₅₄).

A compound (L-82) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, and T represents any substituents indicated in Table 1to Table 6 (hereinafter, referred to as Compound Class SX₁₀₅₅).

A compound (L-82) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, and T represents any substituents indicated in Table 1 toTable 6 (hereinafter, referred to as Compound Class SX₁₀₅₆).

A compound (L-82) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, and T represents any substituents indicated in Table1 to Table 6 (hereinafter, referred to as Compound Class SX₁₀₅₇).

A compound (L-82) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, and T represents any substituents indicated in Table1 to Table 6 (hereinafter, referred to as Compound Class SX₁₀₅₈).

A compound represented by formula (L-83):

(hereinafter, referred to as Compound (L-83)) wherein A¹ represents CH,R⁴ represents a hydrogen atom, R⁵ represents a methyl group, and Trepresents any substituents indicated in Table 1 to Table 6(hereinafter, referred to as Compound Class SX₁₀₅₉).

A compound (L-83) wherein A¹ represents CH, R⁴ represents a hydrogenatom, R⁵ represents a methyl group, and T represents any substituentsindicated in Table 1 to Table 6 (hereinafter, referred to as CompoundClass SX₁₀₆₀).

A compound (L-83) wherein A¹ represents a nitrogen atom, R⁴ represents ahydrogen atom, R⁵ represents a methyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₁₀₆₁).

A compound (L-83) wherein A¹ represents a nitrogen atom, R⁴ represents ahydrogen atom, R⁵ represents an ethyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₁₀₆₂).

A compound (L-83) wherein A¹ represents a nitrogen atom, R⁴ represents ahydrogen atom, R⁵ represents propyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₁₀₆₃).

A compound (L-83) wherein A¹ represents a nitrogen atom, R⁴ represents ahydrogen atom, R⁵ represents an isopropyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₁₀₆₄).

A compound (L-83) wherein A¹ represents a nitrogen atom, R⁴ represents ahydrogen atom, R⁵ represents a cyclopropyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₁₀₆₅).

A compound (L-83) wherein A¹ represents a nitrogen atom, R⁴ represents achlorine atom, R⁵ represents a methyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₁₀₆₆).

A compound (L-83) wherein A¹ represents a nitrogen atom, R⁴ represents achlorine atom, R⁵ represents an ethyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₁₀₆₇).

A compound (L-83) wherein A¹ represents a nitrogen atom, R⁴ represents achlorine atom, R⁵ represents a propyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₁₀₆₈).

A compound (L-83) wherein A¹ represents a nitrogen atom, R⁴ represents achlorine atom, R⁵ represents an isopropyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₁₀₆₉).

A compound (L-83) wherein A¹ represents a nitrogen atom, R⁴ represents achlorine atom, R⁵ represents a cyclopropyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₁₀₇₀).

A compound (L-83) wherein A¹ represents a nitrogen atom, R⁴ represents amethyl group, R⁵ represents a methyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₁₀₇₁).

A compound (L-83) wherein A¹ represents a nitrogen atom, R⁴ represents amethyl group, R⁵ represents an ethyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₁₀₇₂).

A compound (L-83) wherein A¹ represents a nitrogen atom, R⁴ represents amethyl group, R⁵ represents a propyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₁₀₇₃).

A compound (L-83) wherein A¹ represents a nitrogen atom, R⁴ represents amethyl group, R⁵ represents an isopropyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₁₀₇₄).

A compound (L-83) wherein A¹ represents a nitrogen atom, R⁴ represents amethyl group, R⁵ represents a cyclopropyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₁₀₇₅).

A compound represented by formula (L-64):

(hereinafter, referred to as Compound (L-84)) wherein A¹ represents CH,R⁵ represents a methyl group, and T represents any substituentsindicated in Table 1 to Table 6 (hereinafter, referred to as CompoundClass SX₁₀₇₆).

A compound (L-84) wherein A¹ represents CH, R⁵ represents an ethylgroup, and T represents any substituents indicated in Table 1 to Table 6(hereinafter, referred to as Compound Class SX₁₀₇₇).

A compound (L-84) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, and T represents any substituents indicated in Table 1 toTable 6 (hereinafter, referred to as Compound Class SX₁₀₇₈).

A compound (L-84) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, and T represents any substituents indicated in Table 1to Table 6 (hereinafter, referred to as Compound Class SX₁₀₇₉).

A compound (L-84) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, and T represents any substituents indicated in Table 1 toTable 6 (hereinafter, referred to as Compound Class SX₁₀₈₀).

A compound (L-84) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, and T represents any substituents indicated in Table1 to Table 6 (hereinafter, referred to as Compound Class SX₁₀₈₁).

A compound (L-84) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, and T represents any substituents indicated in Table1 to Table 6 (hereinafter, referred to as Compound Class SX₁₀₈₂).

A compound represented by formula (L-85):

(hereinafter, referred to as Compound (L-85)) wherein A¹ represents CH,R⁴ represents a hydrogen atom, R⁵ represents a methyl group, and Trepresents any substituents indicated in Table 1 to Table 6(hereinafter, referred to as Compound Class SX₁₀₈₃).

A compound (L-85) wherein A¹ represents CH, R⁴ represents a hydrogenatom, R⁵ represents an ethyl group, and T represents any substituentsindicated in Table 1 to Table 6 (hereinafter, referred to as CompoundClass SX₁₀₈₄).

A compound (L-85) wherein A¹ represents a nitrogen atom, R⁴ represents ahydrogen atom, R⁵ represents a methyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₁₀₈₅).

A compound (L-85) wherein A¹ represents a nitrogen atom, R⁴ represents ahydrogen atom, R⁵ represents an ethyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₁₀₈₆).

A compound (L-85) wherein A¹ represents a nitrogen atom, R⁴ represents ahydrogen atom, R⁵ represents a propyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₁₀₈₇).

A compound (L-85) wherein A¹ represents a nitrogen atom, R⁴ represents ahydrogen atom, R⁵ represents an isopropyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₁₀₈₈).

A compound (L-85) wherein A¹ represents a nitrogen atom, R⁴ represents ahydrogen atom, R⁵ represents a cyclopropyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₁₀₈₉).

A compound (L-85) wherein A¹ represents a nitrogen atom, R⁴ represents achlorine atom, R⁵ represents a methyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₁₀₉₀).

A compound (L-85) wherein A¹ represents a nitrogen atom, R⁴ represents achlorine atom, R⁵ represents an ethyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₁₀₉₁).

A compound (L-85) wherein A¹ represents a nitrogen atom, R⁴ represents achlorine atom, R⁵ represents a propyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₁₀₉₂).

A compound (L-85) wherein A¹ represents a nitrogen atom, R⁴ represents achlorine atom, R⁵ represents an isopropyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₁₀₉₃).

A compound (L-8 wherein A¹ represents a nitrogen atom, R⁴ represents achlorine atom, R⁵ represents a cyclopropyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₁₀₉₄).

A compound (L-85) wherein A¹ represents a nitrogen atom, R⁴ represents amethyl group, R⁵ represents a methyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₁₀₉₅).

A compound (L-85) wherein A¹ represents a nitrogen atom, R⁴ represents amethyl group, R⁵ represents an ethyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₁₀₉₆).

A compound (L-85) wherein A¹ represents a nitrogen atom, R⁴ represents amethyl group, R⁵ represents a propyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₁₀₉₇).

A compound (L-85) wherein A¹ represents a nitrogen atom, R⁴ represents amethyl group, R⁵ represents an isopropyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₁₀₉₈).

A compound (L-85) wherein A¹ represents a nitrogen atom, R⁴ represents amethyl group, R⁵ represents a cyclopropyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₁₀₉₉).

A compound represented by formula (L-86):

(hereinafter, referred to as Compound (L-86)) wherein A¹ represents CH,R⁵ represents a methyl group, and T represents any substituentsindicated in Table 1 to Table 6 (hereinafter, referred to as CompoundClass SX₁₁₀₀).

A compound (L-86) wherein A¹ represents CH, R⁵ represents an ethylgroup, and T represents any substituents indicated in Table 1 to Table 6(hereinafter, referred to as Compound Class SX₁₁₀₁).

A compound (L-86) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, and T represents any substituents indicated in Table 1 toTable 6 (hereinafter, referred to as Compound Class SX₁₁₀₂).

A compound (L-86) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, and T represents any substituents indicated in Table 1to Table 6 (hereinafter, referred to as Compound Class SX₁₁₀₃).

A compound (L-86) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, and T represents any substituents indicated in Table 1 toTable 6 (hereinafter, referred to as Compound Class SX₁₁₀₄).

A compound (L-86) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, and T represents any substituents indicated in Table1 to Table 6 (hereinafter, referred to as Compound Class SX₁₁₀₅).

A compound (L-86) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, and T represents any substituents indicated in Table1 to Table 6 (hereinafter, referred to as Compound Class SX₁₁₀₆).

A compound represented by formula (L-87):

(hereinafter, referred to as Compound (L-87)) wherein A¹ represents CH,R⁴ represents a hydrogen atom, R⁵ represents a methyl group, and Trepresents any substituents indicated in Table 1 to Table 6(hereinafter, referred to as Compound Class SX₁₁₀₇).

A compound (L-87) wherein A¹ represents CH, R⁴ represents a hydrogenatom, R⁵ represents an ethyl group, and T represents any substituentsindicated in Table 1 to Table 6 (hereinafter, referred to as CompoundClass SX₁₁₀₈).

A compound (L-87) wherein A¹ represents a nitrogen atom, R⁴ represents ahydrogen atom, R⁵ represents a methyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₁₁₀₉).

A compound (L-87) wherein A¹ represents a nitrogen atom, R⁴ represents ahydrogen atom, R⁵ represents an ethyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₁₁₁₀).

A compound (L-87) wherein A¹ represents a nitrogen atom, R⁴ represents ahydrogen atom, R⁵ represents a propyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₁₁₁₁).

A compound (L-87) wherein A¹ represents a nitrogen atom, R⁴ represents ahydrogen atom, R⁵ represents an isopropyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₁₁₁₂).

A compound (L-87) wherein A¹ represents a nitrogen atom, R⁴ represents ahydrogen atom, R⁵ represents a cyclopropyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₁₁₁₃).

A compound (L-87) wherein A¹ represents a nitrogen atom, R⁴ represents achlorine atom, R⁵ represents a methyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₁₁₁₄).

A compound (L-87) wherein A¹ represents a nitrogen atom, R⁴ represents achlorine atom, R⁵ represents an ethyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₁₁₁₅).

A compound (L-87) wherein A¹ represents a nitrogen atom, R⁴ represents achlorine atom, R⁵ represents a propyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₁₁₁₆).

A compound (L-87) wherein A¹ represents a nitrogen atom, R⁴ represents achlorine atom, R⁵ represents an isopropyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₁₁₁₇).

A compound (L-87) wherein A¹ represents a nitrogen atom, R⁴ represents achlorine atom, R⁵ represents a cyclopropyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₁₁₁₈).

A compound (L-87) wherein A¹ represents a nitrogen atom, R⁴ represents achlorine atom, R⁵ represents a methyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₁₁₁₉).

A compound (L-87) wherein A¹ represents a nitrogen atom, R⁴ represents achlorine atom, R⁵ represents an ethyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred to,Compound Class SX₁₁₂₀).

A compound (L-87) wherein A¹ represents a nitrogen atom, R⁴ represents achlorine atom, R⁵ represents a propyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₁₁₂₁).

A compound (L-87) wherein A¹ represents a nitrogen atom, R⁴ represents achlorine atom, R⁵ represents an isopropyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₁₁₂₂).

A compound (L-67) wherein A¹ represents a nitrogen atom, R⁴ represents achlorine atom, R⁵ represents a cyclopropyl group, and T represents anysubstituents indicated in Table 1 to Table 6 (hereinafter, referred toas Compound Class SX₁₁₂₃).

A compound represented by formula (L-88):

(hereinafter, referred to as Compound (L-88)) wherein A¹ represents CH,R⁵ represents a methyl group, and T represents any substituentsindicated in Table 1 to Table 6 (hereinafter, referred to as CompoundClass SX₁₁₂₄).

A compound (L-88) wherein A¹ represents CH, R⁵ represents an ethylgroup, and T represents any substituents indicated in Table 1 to Table 6(hereinafter, referred to as Compound Class SX₁₁₂₅).

A compound (L-88) wherein A¹ represents a nitrogen atom, R⁵ represents amethyl group, and T represents any substituents indicated in Table 1 toTable 6 (hereinafter, referred to as Compound Class SX₁₁₂₆).

A compound (L-88) wherein A¹ represents a nitrogen atom, R⁵ representsan ethyl group, and T represents any substituents indicated in Table 1to Table 6 (hereinafter, referred to as Compound Class SX₁₁₂₇).

A compound (L-88) wherein A¹ represents a nitrogen atom, R⁵ represents apropyl group, and T represents any substituents indicated in Table 1 toTable 6 (hereinafter, referred to as Compound Class SX₁₁₂₈).

A compound (L-88) wherein A¹ represents a nitrogen atom, R⁵ representsan isopropyl group, and T represents any substituents indicated in Table1 to Table 6 (hereinafter, referred to as Compound Class SX₁₁₂₉).

A compound (L-88) wherein A¹ represents a nitrogen atom, R⁵ represents acyclopropyl group, and T represents any substituents indicated in Table1 to Table 6 (hereinafter, referred to as Compound Class SX₁₁₃₀).

Next, specific examples of an intermediate compound for preparing thecompound Z of the present invention are indicated below.

A compound represented by formula (LL-1):

(hereinafter, referred to as Compound (LL-1)) wherein R^(w) represents ahydrogen atom, and T^(W) represents any substituents indicated in Table1 to Table 6 and Table 16.

TABLE 16 SMe SEt SPr S(i-Pr) S(O)Me S(O)Et S(O)Pr S(O)i-Pr S(O)₂MeS(O)₂Et S(O)₂Pr S(O)₂i-Pr OS(O)₂Me OS(O)₂Et OS(O)₂Pr OMe Oi-Pr OCH₂OMeOBn OCH₂(4-OMe—Ph) OC(O)Me OC(O)Et OC(O)CMe₃ OH F Cl Br I

A compound (LL-1) wherein R^(w) represents a methyl group, and T^(W)represents any substituents indicated in Table 1 to Table 6 and Table16.

A compound (LL-1) wherein R^(w) represents a benzyl group, and T^(W)represents any substituents indicated in Table 1 to Table 6 and Table16.

A compound represented by formula (LL-2):

(hereinafter, referred to as Compound (LL-2)) wherein R^(w) represents ahydrogen atom, and T^(W) represents any substituents indicated in Table1 to Table 6 and Table 16.

A compound (LL-2) wherein R^(w) represents a methyl group, and T^(W)represents any substituents indicated in Table 1 to Table 6 and Table16.

A compound (LL-2) wherein R^(w) represents a benzyl group, and T^(W)represents any substituents indicated in Table 1 to Table 6 and Table16.

A compound represented by formula (LL-3):

(hereinafter, referred to as Compound (LL-3)) wherein R^(w) represents ahydrogen atom, and T^(W) represents any substituents indicated in Table1 to Table 6 and Table 16.

A compound (LL-3) wherein R^(w) represents a methyl group, and T^(W)represents any substituents indicated in Table 1 to Table 6 and Table16.

A compound (LL-3) wherein R^(ow) represents a benzyl group, and T^(W)represents any substituents indicated in Table 1 to Table 6 and Table16.

A compound represented by formula (LL-4):

(hereinafter, referred to as Compound (LL-4)) wherein R^(ow) representsa hydrogen atom, and T^(W) represents any substituents indicated inTable 1 to Table 6 and Table 16.

A compound (LL-4) wherein R^(w) represents a methyl group, and T^(W)represents any substituents indicated in Table 1 to Table 6 and Table16.

A compound (LL-4) wherein R^(w) represents a benzyl group, and T^(W)represents any substituents indicated in Table 1 to Table 6 and Table16.

A compound represented by formula (LL-5):

(hereinafter, referred to as Compound (LL-5)) wherein R^(w) represents ahydrogen atom, and T^(w) represents any substituents indicated in Table1 to Table 6 and Table 16.

A compound (LL-5) wherein R^(w) represents a methyl group, and T^(W)represents any substituents indicated in Table 1 Table 6 and Table 16.

A compound (LL-5) wherein R^(w) represents a benzyl group, and T^(W)represents any substituents indicated in Table 1 to Table 6 and Table16.

A compound represented by formula (LL-6):

(hereinafter, referred to as Compound (LL-6)) wherein A¹ represents CH,A² and A³ represent CH, R^(w) represents a hydrogen atom, n is 0, andT^(W2) represents any substituents indicated in Table 1 to Table 6 andTable 16.

A compound (LL-6) wherein A¹ represents CH, A² and A³ represent CH,R^(w) represents a hydrogen atom, n is 2, and T^(W2) represents anysubstituents indicated in Table 1 to Table 6 and Table 16.

A compound (LL-6) wherein A¹ represents a nitrogen atom, A² and A³represent CH, R^(w) represents a hydrogen atom, n is 0, and T^(W2)represents any substituents indicated in Table 1 to Table 6 and Table16.

A compound (LL-6) wherein A¹ represents a nitrogen atom, A² and A³represent CH, R^(w) represents a hydrogen atom, n is 2, and T^(W2)represents any substituents indicated in Table 1 to Table 6 and Table16.

A compound (LL-6) wherein A¹ represents a nitrogen atom, A² and A³represent CH, R^(w) represents a methyl group, n is 0, and T^(W2)represents any substituents indicated in Table 1 to Table 6 and Table16.

A compound (LL-6) wherein A¹ represents a nitrogen atom, A² and A³represent CH, R^(w) represents a methyl group, n is 2, and T^(W2)represents any substituents indicated in Table 1 to Table 6 and Table16.

A compound (LL-6) wherein A¹ represents a nitrogen atom, A² and A³represent CH, R^(w) represents a benzyl group, n is 0, and T^(W2)represents any substituents indicated in Table 1 to Table 6 and Table16.

A compound (LL-6) wherein A¹ represents a nitrogen atom, A² and A³represent CH, R^(w) represents a benzyl group, n is 2, and T^(W2)represents any substituents indicated in Table 1 to Table 6 and Table16.

A compound (LL-6) wherein A¹ represents a nitrogen atom, A² representsCH, A³ represents a nitrogen atom, R^(w) represents a hydrogen atom, nis 0, and T^(W2) represents any substituents indicated in Table 1 toTable 6 and Table 16.

A compound (LL-6) wherein A¹ represents a nitrogen atom, A² representsCH, A³ represents a nitrogen atom, R^(w) represents a hydrogen atom, nis 2, and T^(W2) represents any substituents indicated in Table 1 toTable 6 and Table 16.

A compound (LL-6) wherein A¹ represents a nitrogen atom, represents CH,A³ represents a nitrogen atom, R^(w) represents a methyl group, n is 0,and T^(W2) represents any substituents indicated in Table 1 to Table 6and Table 16.

A compound (LL-6) wherein A¹ represents a nitrogen atom, A² representsCH, A³ represents a nitrogen atom, R^(w) represents a methyl group, n is2, and T^(W2) represents any substituents indicated in Table 1 to Table6 and Table 16.

A compound (LL-6) wherein A¹ represents a nitrogen atom, A² representsCH, A³ represents a nitrogen atom, R^(w) represents a benzyl group, n is0, and T^(W2) represents any substituents indicated in Table 1 to Table6 and Table 16.

A compound (LL-6) wherein A¹ represents a nitrogen atom, A² representsCH, A³ represents a nitrogen atom, R^(w) represents a benzyl group, n is2, and T^(W2) represents any substituents indicated in Table 1 to Table6 and Table 16.

A compound represented by formula (LL-7):

(hereinafter, referred to as Compound (LL-1)) wherein A¹ represents CH,A² and A⁴ represent CH, R^(w) represents a hydrogen atom, n is 0, andT^(W2) represents any substituents indicated in Table 1 to Table 6 andTable 16.

A compound (LL-7) wherein A¹ represents CH, A² and A⁴ represent CH,R^(w) represents a hydrogen atom, n is 2, and T^(W2) represents anysubstituents indicated in Table 1 to Table 6 and Table 16.

A compound (LL-7) wherein A¹ represents a nitrogen atom, A² and A⁴represent CH, R^(w) represents a hydrogen atom, n is 0, and T^(W2)represents any substituents indicated in Table 1 to Table 6 and Table16.

A compound (LL-7) wherein A¹ represents a nitrogen atom, A² and A⁴represent CH, R^(w) represents a hydrogen atom, n is 2, and T^(W2)represents any substituents indicated in Table 1 to Table 6 and Table16.

A compound (LL-7) wherein A¹ represents a nitrogen atom, A² and A⁴represent CH, R^(w) represents a methyl group, n is 0, and T^(W2)represents any substituents indicated in Table 1 to Table 6 and Table16.

A compound (LL-7) wherein A¹ represents a nitrogen atom, A² and A⁴represent CH, R^(w) represents a methyl group, n and T^(W2) representsany substituents indicated in Table 1 to Table 6 and Table 16.

A compound (LL-7) wherein A¹ represents a nitrogen atom, A² and A⁴represent CH, R^(w) represents a benzyl group, n is 0, and T^(W2)represents any substituents indicated in Table 1 to Table 6 and Table16.

A compound (LL-7) wherein A¹ represents a nitrogen atom, A² and A⁴represent CH, R^(w) represents a benzyl group, n is 2, and T^(W2)represents any substituents indicated in Table 1 to Table 6 and Table16.

A compound (LL-7) wherein A¹ represents a nitrogen atom, A² representsCH, A⁴ represents a nitrogen atom, R^(w) represents a hydrogen atom, nis 0, and T^(W2) represents any substituents indicated in Table 1 toTable 6 and Table 16.

A compound (LL-7) wherein A¹ represents a nitrogen atom, A² representsCH, A⁴ represents a nitrogen atom, R^(w) represents a hydrogen atom, nis 2, and T^(W2) represents any substituents indicated in Table 1 toTable 6 and Table 16.

A compound (LL-7) wherein A¹ represents a nitrogen atom, A² representsCH, A⁴ represents a nitrogen atom, R^(w) represents a methyl group, n is0, and T^(W2) represents any substituents indicated in Table 1 to Table6 and Table 16.

A compound (LL-7) wherein A¹ represents a nitrogen atom, A² representsCH, A⁴ represents a nitrogen atom, R^(w) represents a methyl group, n is2, and T^(W2) represents any substituents indicated in Table 1 to Table6 and Table 16.

A compound (LL-7) wherein A¹ represents a nitrogen atom, A² representsCH, A⁴ represents a nitrogen atom, R^(w) represents a benzyl group, n is0, and T^(W2) represents any substituents indicated in Table 1 to Table6 and Table 16.

A compound (LL-7) wherein A¹ represents a nitrogen atom, A² representsCH, A⁴ represents a nitrogen atom, R^(w) represents a benzyl group, n is2, and T^(W2) represents any substituents indicated in Table 1 to Table6 and Table 16.

A compound represented by formula (LL-8):

(hereinafter, referred to as Compound (LL-8)) wherein A¹ represents CH,A² and A³ represent CH, R^(w) represents a hydrogen atom, n is 0, R^(3b)represents a hydrogen atom, and R^(3c) represents any substituentsindicated in Table 7 to Table 15.

A compound (LL-8) wherein A¹ represents CH, A² and A³ represent CH,R^(w) represents a hydrogen atom, n is 2, R^(3b) represents a hydrogenatom, and R^(3c) represents any substituents indicated in Table 7 toTable 15.

A compound (LL-8) wherein A¹ represents CH, A² and A³ represent CH,R^(w) represents a hydrogen atom, n is 0, R^(3c) represents a hydrogenatom, and R^(3b) represents any substituents indicated in Table 7 toTable 15.

A compound (LL-8) wherein A¹ represents CH, A² and A³ represent CH,R^(w) represents a hydrogen atom, n is 2, R^(3c) represents a hydrogenatom, and R^(3b) represents any substituents indicated in Table 7 toTable 15.

A compound (LL-8) wherein A¹ represents a nitrogen atom, A² and A³represent CH, R^(w) represents a hydrogen atom, n is 0, R^(3c)represents a hydrogen atom, and R^(3b) represents any substituentsindicated in Table 7 to Table 15.

A compound (LL-8) wherein A¹ represents a nitrogen atom, A² and A³represent CH, R^(w) represents a hydrogen atom, n is 2, R^(3c)represents a hydrogen atom, and R^(3b) represents any substituentsindicated in Table 7 to Table 15.

A compound (LL-8) wherein A¹ represents a nitrogen atom, A² and A³represent CH, R^(w) represents a hydrogen atom, n is 0, R^(3c)represents a hydrogen atom, and R^(3b) represents any substituentsindicated in Table 7 to Table 15.

A compound (LL-8) wherein A¹ represents a nitrogen atom, A¹ and A³represent CH, R^(w) represents a hydrogen atom, n is 2, R^(3c)represents a hydrogen atom, and R^(3b) represents any substituentsindicated in Table 7 to Table 15.

A compound (LL-8) wherein A¹ represents a nitrogen atom, A² and A³represent CH, R^(w) represents a methyl group, n is 0, R^(3b) representsa hydrogen atom, and R^(3c) represents any substituents indicated inTable 7 to Table 15.

A compound (LL-8) wherein A¹ represents a nitrogen atom, A² and A³represent CH, R^(w) represents a methyl group, n is 2, R^(3b) representsa hydrogen atom, and R^(3c) represents any substituents indicated inTable 7 to Table 15.

A compound (LL-8) wherein A¹ represents a nitrogen atom, A² and A³represent CH, R^(w) represents a methyl group, n is 0, R^(3c) representsa hydrogen atom, and R^(3b) represents any substituents indicated inTable 7 to Table 15.

A compound (LL-8) wherein A¹ represents a nitrogen atom, A² and A³represent CH, R^(w) represents a methyl group, n is 2, R^(3c) representsa hydrogen atom, and R^(3b) represents any substituents indicated inTable 7 to Table 15.

A compound (LL-8) wherein A¹ represents a nitrogen atom, A² representsCH, A³ represents a nitrogen atom, R^(w) represents a hydrogen atom, is0, R^(3b) represents a hydrogen atom, and R^(3c) represents anysubstituents indicated in Table 7 to Table 15.

A compound (LL-8) wherein A¹ represents a nitrogen atom, A² representsCH, A³ represents a nitrogen atom, R^(w) represents a hydrogen atom, nis 2, R^(3b) represents a hydrogen atom, and R^(3c) represents anysubstituents indicated in Table 7 to Table 15.

A compound (LL-8) wherein A¹ represents a nitrogen atom, A² representsCH, R^(w) represents a hydrogen atom, n is 0, R^(3c) represents ahydrogen atom, and R^(3b) represents any substituents indicated in Table7 to Table 15.

A compound (LL-8) wherein A¹ represents a nitrogen atom, A² representsCH, A³ represents a nitrogen atom, R^(w) represents a hydrogen atom, nis 2, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15.

A compound (LL-8) wherein A¹ represents a nitrogen atom, A² representsCH, A³ represents a nitrogen atom, R^(w) represents a methyl group, n is0, R^(3b) represents a hydrogen atom, and R^(3c) represents anysubstituents indicated in Table 7 to Table 15.

A compound (LL-8) wherein A¹ represents a nitrogen atom, A² representsCH, A³ represents a nitrogen atom, R^(w) represents a methyl group, n is2, R^(3b) represents a hydrogen atom, and R^(3c) represents anysubstituents indicated in Table 7 to Table 15.

A compound (LL-8) wherein A¹ represents a nitrogen atom, A² representsCH, A³ represents a nitrogen atom, R^(w) represents a methyl group, n is0, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15.

A compound (LL-8) wherein A¹ represents a nitrogen atom, A² representsCH, A³ represents a nitrogen atom, R^(w) represents a methyl group, n is2, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15.

A compound represented by formula (LL-9):

(hereinafter, referred to as Compound (LL-9)) wherein A¹ represents CH,A² and A⁴ represent CH, R^(w) represents a hydrogen atom, n is 0, R^(3b)represents a hydrogen atom, and R^(3c) represents any substituentsindicated in Table 7 to Table 15.

A compound (LL-9) wherein A¹ represents CH, A² and A⁴ represent CH,R^(w) represents a hydrogen atom, a is 2, R^(3b) represents a hydrogenatom, and R^(3c) represents any substituents indicated in Table 7 toTable 15.

A compound (LL-9) wherein A¹ represents CH, A² and A⁴ represent CH,R^(w) represents a hydrogen atom, n is 0, R^(3c) represents a hydrogenatom, and R^(3b) represents any substituents indicated in Table 7 toTable 15.

A compound (LL-9) wherein A¹ represents CH, A² and A⁴ represent CH,R^(w) represents a hydrogen atom, n is 2, R^(3c) represents a hydrogenatom, and R^(3b) represents any substituents indicated in Table 7 toTable 15.

A compound (LL-9) wherein A¹ represents a nitrogen atom, A² and A⁴represent CH, R^(w) represents a hydrogen atom, n is 0, R^(3b)represents a hydrogen atom, and R^(3c) represents any substituentsindicated in Table 7 to Table 15.

A compound (LL-9) wherein A¹ represents a nitrogen atom, A² and A⁴represent CH, R^(w) represents a hydrogen atom, n is 0, R^(3b)represents a hydrogen atom, and R^(3c) represents any substituentsindicated in Table 7 to Table 15.

A compound (LL-9) wherein A¹ represents a nitrogen atom, A² and A⁴represent CH, R^(w) represents a hydrogen atom, n is 0, R^(3c)represents a hydrogen atom, and R^(3b) represents any substituentsindicated in Table 7 to Table 15.

A compound (LL-9) wherein A¹ represents a nitrogen atom, A² and A⁴represent CH, R^(w) represents a hydrogen atom, n is 2, R^(3c)represents a hydrogen atom, and R^(3b) represents any substituentsindicated in Table 7 to Table 15.

A compound (LL-9) wherein A¹ represents a nitrogen atom, A² and A⁴represent CH, R^(w) represents a methyl group, n is 0, R^(3b) representsa hydrogen atom, and R^(3c) represents any substituents indicated inTable 7 to Table 15.

A compound (LL-9) wherein A¹ represents a nitrogen atom, A² and A⁴represent CH, R^(w) represents a methyl group, n is 2, R^(3b) representsa hydrogen atom, and R^(3c) represents any substituents indicated inTable 7 to Table 15.

A compound (LL-9) wherein A¹ represents a nitrogen atom, A² and A⁴represent CH, R^(w) represents a methyl group, n is 0, R^(3c) representsa hydrogen atom, and R^(3b) represents any substituents indicated inTable 7 to Table 15.

A compound (LL-9) wherein A¹ represents a nitrogen atom, A² and A⁴represent CH, R^(w) represents a methyl group, n is 2, R^(3c) representsa hydrogen atom, and R^(3b) represents any substituents indicated inTable 7 to Table 15.

A compound (LL-9) wherein A¹ represents a nitrogen atom, A² representsCH, A⁴ represents a nitrogen atom, R^(w) represents a hydrogen atom, nis 0, R^(3b) represents a hydrogen atom, and R^(3c) represents anysubstituents indicated in Table 7 to Table 15.

A compound (LL-9) wherein A¹ represents a nitrogen atom, A² representsCH, A⁴ represents a nitrogen atom, R^(w) represents a hydrogen atom, nis 2, R^(3b) represents a hydrogen atom, and R^(3c) represents anysubstituents indicated in Table 7 to Table 15.

A compound (LL-9) wherein A¹ represents a nitrogen atom, A² representsCH, A⁴ represents a nitrogen atom, R^(w) represents a hydrogen atom, nis 0, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15.

A compound (LL-9) wherein A¹ represents a nitrogen atom, A² representsCH, A⁴ represents a nitrogen atom, R^(w) represents a hydrogen atom, nis 2, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15.

A compound (LL-9) wherein A¹ represents a nitrogen atom, A² representsCH, A⁴ represents a nitrogen atom, R^(w) represents a methyl group, n is0, R^(3b) represents a hydrogen atom, and R^(3c) represents anysubstituents indicated in Table 7 to Table 15.

A compound (LL-9) wherein A¹ represents a nitrogen atom, A² representsCH, A⁴ represents a nitrogen atom, R^(w) represents a methyl group, n is2, R^(3b) represents a hydrogen atom, and R^(3c) represents anysubstituents indicated in Table 7 to Table 15.

A compound (LL-9) wherein A¹ represents a nitrogen atom, A² representsCH, A⁴ represents a nitrogen atom, R^(w) represents a methyl group, n is0, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15.

A compound (LL-9) wherein A¹ represents a nitrogen atom, A² representsCH, A⁴ represents a nitrogen atom, R^(w) represents a methyl group, n is2, R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated, in Table 7 to Table 15.

A compound represented by formula (LL-10):

(hereinafter, referred to as Compound (LL-10)) wherein A¹ represents CH,A² and A³ represent CH, R⁵ represents a methyl group, n is 0, R^(3b)represents a hydrogen atom, and R^(3c) represents any substituentsindicated in Table 7 to Table 15.

A compound (LL-10) wherein A¹ represents CH, A² and A³ represent CH, R⁵represents a methyl group, n is 2, R^(3b) represents a hydrogen atom,and R^(3c) represents any substituents indicated in Table 7 to Table 1.5

A compound (LL-10) wherein A¹ represents CH, A² and A³ represent CH, R⁵represents a methyl group, n is 0, R^(3c) represents a hydrogen atom,and R^(3b) represents any substituents indicated in Table 7 to Table 15.

A compound (LL-10) wherein A¹ represents CH, A² and A³ represent CH, R⁵represents a methyl group, n is 2, R^(3c) represents a hydrogen atom,and R^(3b) represents any substituents indicated in Table 7 to Table 15.

A compound (LL-10) wherein A¹ represents a nitrogen atom, A² and A³represent CH, R⁵ represents a methyl group, n is 0, R^(3b) represents ahydrogen atom, and R^(3c) represents any substituents indicated in Table7 to Table 15.

A compound (LL-10) wherein A¹ represents a nitrogen atom, A² and A³represent CH, R⁵ represents a methyl group, n is 2, R^(3b) represents ahydrogen atom, and R^(3c) represents any substituents indicated in Table7 to Table 15.

A compound (LL-10) wherein A¹ represents a nitrogen atom, A² and A³represent CH, R⁵ represents a methyl group, n is 0, R^(3b) represents ahydrogen atom, and R^(3c) represents any substituents indicated in Table7 to Table 15.

A compound (LL-10) wherein A¹ represents a nitrogen atom, A² and A³represent CH, R⁵ represents a methyl group, n is 2, R^(3c) represents ahydrogen atom, and R^(3b) represents any substituents indicated in Table7 to Table 15.

A compound (LL-10) wherein A¹ represents a nitrogen atom, A² representsCH, A³ represents a nitrogen atom, R⁵ represents a methyl group, n is 0,R^(3b) represents a hydrogen atom, and R^(3c) represents anysubstituents indicated in Table 7 to Table 15.

A compound (LL-10) wherein A¹ represents a nitrogen atom, A² representsCH, A³ represents a nitrogen atom, R⁵ represents a methyl group, n is 2,R^(3b) represents a hydrogen atom, and R^(3c) represents anysubstituents indicated in Table 7 to Table 15.

A compound (LL-10) wherein A¹ represents a nitrogen atom, A² representsCH, A³ represents a nitrogen atom, R⁵ represents a methyl group, n is 0,R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15.

A compound (LL-10) wherein A¹ represents a nitrogen atom, A² representsCH, A³ represents a nitrogen atom, R⁵ represents a methyl group, n is 2,R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15.

A compound represented by formula (LL-11):

(hereinafter, referred to as Compound (LL-11)) wherein A¹ represents CH,A² and A³ represent CH, R⁵ represents a methyl group, R^(3b) representsa hydrogen atom, and R^(3c) represents any substituents indicated inTable 7 to Table 15.

A compound (LL-11) wherein A¹ represents CH, A² and A³ represent CH, R⁵represents a methyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15.

A compound (LL-11) wherein A¹ represents a nitrogen atom, A² and A³represent CH, R⁵ represents a methyl group, R^(3b) represents a hydrogenatom, and R^(3c) represents any substituents indicated in Table 7 toTable 15.

A compound (LL-11) wherein A¹ represents a nitrogen atom, A² and A³represent CH, R⁵ represents a methyl group, R^(3c) represents a hydrogenatom, and R^(3b) represents any substituents indicated in Table 7 toTable 15.

A compound (LL-11) wherein A¹ represents a nitrogen atom, A² representsCH, A³ represents a nitrogen atom, R⁵ represents a methyl group, R^(3b)represents a hydrogen atom, and R^(3c) represents any substituentsindicated in Table 7 to Table 15.

A compound (LL-11) wherein A¹ represents a nitrogen atom, A² representsCH, A³ represents a nitrogen atom, R⁵ represents a methyl group, R^(3c)represents a hydrogen atom, and R^(3b) represents any substituentsindicated in Table 7 to Table 15.

A compound represented by formula (LL-12):

(hereinafter, referred to as Compound (LL-12)) wherein A¹ represents CH,A² and A³ represent CH, R⁵ represents a methyl group, n is 0, R^(3b)represents a hydrogen atom, and R^(3c) represents any substituentsindicated in Table 7 to Table 15.

A compound (LL-12) wherein A¹ represents CH, A² and A³ represent CH, R⁵represents a methyl group, n is 2, R^(3b) represents a hydrogen atom,and R^(3c) represents any substituents indicated in Table 7 to Table 15.

A compound (LL-12) wherein A¹ represents CH, A² and A³ represent CH, R⁵represents a methyl group, n is 0, R^(3c) represents a hydrogen atom,and R^(3b) represents any substituents indicated in Table 7 to Table 15.

A compound (LL-12) wherein A¹ represents CH, A² and A³ represent CH, R⁵represents a methyl group, n is 2, R^(3c) represents a hydrogen atom,and R^(3b) represents any substituents indicated in Table 7 to Table 15.

A compound (LL-12) wherein A¹ represents a nitrogen atom, A² and A³represent CH, R⁵ represents a methyl group, n is 0, R^(3b) represents ahydrogen atom, and R^(3c) represents any substituents indicated in Table7 to Table 15.

A compound (LL-12) wherein A¹ represents a nitrogen atom, A² and A³represent CH, R⁵ represents a methyl group, n is 2, R^(3b) represents ahydrogen atom, and R^(3c) represents any substituents indicated in Table7 to Table 15.

A compound (LL-12) wherein A¹ represents a nitrogen atom, A² and A³represent CH, R⁵ represents a methyl group, n is 0, R^(3c) represents ahydrogen atom, and R^(3b) represents any substituents indicated in Table7 to Table 15.

A compound (LL-12) wherein A¹ represents a nitrogen atom, A² and A³represent CH, R⁵ represents a methyl group, n is 2, R^(3c) represents ahydrogen atom, and R^(3b) represents any substituents indicated in Table7 to Table 15.

A compound (LL-12) wherein A¹ represents a nitrogen atom, A² representsCH, A³ represents a nitrogen atom, R⁵ represents a methyl group, n is 0,R^(3b) represents a hydrogen atom, and R^(3c) represents anysubstituents indicated in Table 7 to Table 15.

A compound (LL-12) wherein A¹ represents a nitrogen atom, A² representsCH, A³ represents a nitrogen atom, R⁵ represents a methyl group, n is 2,R^(3b) represents a hydrogen atom, and R^(3c) represents anysubstituents indicated in Table 7 to Table 15.

A compound (LL-12) wherein A¹ represents a nitrogen atom, A² representsCH, A³ represents a nitrogen atom, R⁵ represents a methyl group, n is 0,R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15.

A compound (LL-12) wherein A¹ represents a nitrogen atom, A² representsCH, A³ represents a nitrogen atom, R⁵ represents a methyl group, n is 2,R^(3c) represents a hydrogen atom, and R^(3b) represents anysubstituents indicated in Table 7 to Table 15.

A compound represented by formula (LL-13):

(hereinafter, referred to as Compound (LL-13)) wherein A¹ represents CH,A² and A³ represent CH, R⁵ represents a methyl group, R^(3b) representsa hydrogen atom, and R^(3c) represents any substituents indicated inTable 7 to Table 15.

A compound (LL-13) wherein A¹ represents CH, A² and A³ represent CH, R⁵represents a methyl group, R^(3c) represents a hydrogen atom, and R^(3b)represents any substituents indicated in Table 7 to Table 15.

A compound (LL-13) wherein A¹ represents a nitrogen atom, A² and A³represent CH, R⁵ represents a methyl group, R^(3b) represents a hydrogenatom, and R^(3c) represents any substituents indicated in Table 7 toTable 15.

A compound (LL-13) wherein A¹ represents a nitrogen atom, A² and A³represent CH, R⁵ represents a methyl group, R^(3c) represents a hydrogenatom, and R^(3b) represents any substituents indicated in Table 7 toTable 15.

A compound (LL-13) wherein A¹ represents a nitrogen atom, A² representsCH, A³ represents a nitrogen atom, R⁵ represents a methyl group, R^(3b)represents a hydrogen atom, and R^(3c) represents any substituentsindicated in Table 7 to Table 15.

A compound (LL-13) wherein A¹ represents a nitrogen atom, A² representsCH, A³ represents a nitrogen atom, R⁵ represents a methyl group, R^(3c)represents a hydrogen atom, and R^(3b) represents any substituentsindicated in Table 7 to Table 15.

All the compounds classes SX₁ to SX₁₁₃₀ may be prepared according to themethod described in the Example or the Process described herein.

The Present compound Z may be mixed or combined with one or moreingredients selected from a group consisting of the following Group (a),Group (b), Group (c), Group (d), and Group (e).

The Present compound may be mixed or combined with one or moreingredients selected from a group consisting of the following Group (a),Group (b), Group (c), Group (d), Group (e), Group (f), Group (g), andgroup (h) (hereinafter, referred to as Present ingredient).

The above-mentioned mixing or combining represents a use of Presentcompound Z and the Present ingredient at same time, separately or atcertain intervals.

When the Present compound Z and the present ingredient are used at thesame time, the Present compound Z and the Present ingredient may becontained in separate formulations respectively or may be contained inthe same one formulation.

One aspect of the present invention is a composition comprising one ormore ingredients selected from Group (a) or Group (b) as well as thePresent compound Z.

Group (a) is a group consisting of Acetylcholinesterase inhibitors (forexample, carbamate insecticides, or organophosphorus insecticides),ABA-gated chloride channel blockers (for example, phenylpyrazoleinsecticides), Sodium channel modulators (for example, pyrethroidinsecticides), Nicotinic acetylcholine receptor competitive modulators(for example, neonicotinoid insecticides), Nicotinic acetylcholinereceptor allosteric modulators, Glutamatergic chlorine ion channelallosteric modulators (for example, macrolide insecticides), Juvenilehormone mimic, Multisite inhibitors, chordotonal organ TRPV channelmodulators, Mites growth inhibitors, Mitochondria ATP biosyntheticenzyme inhibitors, Uncouplers of oxidative phosphorylation, Nicotinicacetylcholine receptor channel blocker (for example, Nereistoxininsecticides), Chitin synthesis inhibitors, Molting inhibitors, Ecdysonereceptor agonist, Octopamine receptor agonist, Inhibitors ofMitochondrial electron transport system complex I, II, III and IV,Voltage-dependent sodium channel blockers, Acetyl CoA carboxylaseinhibitor, Ryanodine receptor modulator (for example, Diamideinsecticides), Chordtonal organ modulators, Microbial pesticides, andthe other insecticidal, miticidal or nematicidal active ingredients.These ingredients are classified as a class based on the actionmechanism of IRAC.

Group (b) is a group consisting of Nucleic acid synthesis inhibitors(for example, Phenylamide fungicides, or Acylamino acid fungicides),Cell division and cytoskeleton inhibitors (for example, MBC fungicides),Respiratory inhibitors (for example, QoI fungicides or Qil fulgicides),Amino acid synthesis and protein synthesis inhibitors (for example,anilinopyridine fungicides), Signal transduction inhibitors, Lipidsynthesis and membrane synthesis inhibitors, sterol biosynthesisinhibitors (for example, DMI fungicides such as triazole), Cell wallsynthesis inhibitors, Melanin synthesis inhibitors, Plant defenseinducers, Other action point contact active fungicides, Microbialfungicides, and the other fungicidal ingredients. These are classifiedas a class based on the action mechanism of FRAC.

Group (c) is a plant growth modulating ingredients group consisting ofPlant growth modulating ingredients, Mycorrhizal fungi, and Root nodulebacteria.

Group (d) is a phytotoxicity-reducing ingredient group which reduces thephytotoxicity against the crop when it is used in combination with theother chemicals.

Group (e) is a synergist group which enhances the effectiveness of theother chemicals when it is used in combination with the other chemicals.

Group (f) is a group consisting of repellent components consisting ofbird repellant components, insect repellant components, and animalrepellant components.

Group is a molluscicidal component group.

Group (h) is an insect pheromone group.

Examples of the combination of the Present ingredient and the Presentcompound Z are described below. For example, alanycarb+SX represents acombination of alanycarb and SX

The symbol of “SX” represents any one of the Present compound Z selectedfrom the Compound Class SX₁ to the Compound Class SX₁₁₃₀. Also, all ofthe below-mentioned present ingredient are known ingredients, and arecommercially available or may be produced by the known method. If thepresent ingredient is a bacterium, it is available also from thebacterial authority depository. The numerical number in bracketrepresents a CAS RN (Register Trademark).

Combination of the Present ingredient of the above group (a) and thePresent compound Z:

abamectin+SX, acephate+SX, acequinocyl+SX, acetamiprid+SX,acrinathrin+SX, acynonapyr+SX, afidopyropen+SX, afoxolaner+SX,alanycarb+SX, aldicarb+SX, allethrin+SX, alpha-cypermethrin+SX,alpha-endoaulfan+SX, aluminium phosphide+SX, amitraz+SX,azadirachtin+SX, azamethiphos+SX, azinphos-ethyl+SX, azinphos-methyl+SX,azocyclotin+SX, bark of Celastrus angulatus+SX, bendiocarb+SX,benfluthrin+SX, benfuracarb+SX, bensultap+SX, benzoximate+SX,benzpyrimoxan+SX, beta-cyfluthrin+SX, beta-cypermethrin+SX,bifenazate+SX, bifenthrin+SX, bioallethrin+SX, bioresmethrin+SX,bistrifluron+SX, borax+SX, boric acid+SX, broflanilide+SX,bromopropylate+SX, buprofezin+SX, butocarboxim+SX, butoxycarboxim+SX,cadusafos+SX, calcium cyanide+SX, calcium phosphide+SX, carbaryl+SX,carbofuran+EX, carbosulfan+SX, cartap hydrochloride+SX, cartap+SX,chinomethionat+SX, chlorantraniliprole+SX, chlordane+SX,chloethoxyfos+SX, chlorfenapyr+SX, chlorfenvinphos+SX,chlorfluazuron+SX, chlormephos+SX, chloropicrin+SX, chlorpyrifos+SX,chlorpyrifos-methyl+SX, chromafenozide+SX, clofentezine+SX,clothianidin+SX, coumaphos+SX, cryolite+SX, cyanophos+SX,cyantraniliprole+SX, cycloniliprole+SX, cycloprothrin+SX,cycloxaprid+SX, cyenopyrafen+SX, cyflumetofen+SX, cyfluthrin+SX,cyhalodiamide+SX, cyhalothrin+SX, cyhexatin+SX, cypermethrin+SX,cyphenothrin+SX, cyromazine+SX, dazomet+SX, deltamethrin+SX,demeton-S-methyl+SX, diafenthiuron+SX, diazinon+SX, dichlorvos+SX,dicloromezotiaz+SX, dicofol+SX, dicrotophos+SX, diflovidazin+SX,diflubenzuron+SX, dimefluthrin+SX, dimethoate+SX, dimethylvinphos+SX,dinotefuran+SX, disodium octaborate+SX, disulfoton+SX, DNOC(2-methyl-4,6-dinitrophenol)+SX, dorametin+SX, dried leaves ofDryopteris filix-mas+SX, emamectin-benzoate+SX, empenthrin+SX,endosulfan+SX, EPN (O-ethyl O-(4-nitrophenyl)phenylphosphonothioate)+SX, epsilon-etofluthrin+SX,epsilon-momfluorothrin+SX, esfenvalerate+SX, ethiofencarb+SX, ethion+SX,ethiprole+SX, ethoprophos+SX, etofenprox+SX, etoxazole+SX, extract ofArtemisia absinthium+SX, extract of Cassia nigricans+SX, extract ofClitoria ternatea+SX, extract of Symphytum officinale+SX, extracts orsimulated blend of Chenopodium ambrosioides+SX, extract of Tanacetumvulgare+SX, extract of Urtica dioica+SX, extract of Viscum album+SX,famphur+SX, fenamlphos+SX, fenazaquin+SX, fenbutatin oxide+SX,fenitrothion+SX, fenobucarb+SX, fenoxycarb+SX, fenpropathrin+SX,fenpyroximate+SX, fenthion+SX, fenvalerate+SX, fipronil+SX,flometoquin+SX, flonicamid+SX, fluacrypyrim+SX,fluazaindolizine+fluazuron+SX, flubendiamide+SX, flucycloxuron+SX,flucythrinate+SX, fluensulfone+SX, flufenoprox+SX, flufenoxuron+SX,flufiprole+SX, flumethrin+SX, fluopyram+SX, flupyradifurone+SX,fluralaner+SX, fluvalinate+SX, fluxametamide+SX, formetanate+SX,fosthiazate+SX, furamethrin+SX, furathiocarb+SX, gamma-cyhalothrin+SX,GS-omega/kappa HXTX-Hvla peptide+SX, halfenprox+SX, halofenozide+SX,heptafluthrin+SX, heptenophos+SX, hexaflumuron+SX, hexythiazox+SX,potassium salt of hop beta acid+SX, hydramethylnon+SK, hydroprene+SX,imicyafos+SX, imidacloprid+SX, imiprothrin+SX, indoxacarb+SX,isofenphos+SX, isoprocarb+SX,isopropyl-O-(methoxyaminothiophosphoryl)salicylate+SX, isoxathion+SX,ivermectin+SX, kadethrin+SX, kappa-tefluthrin+SX, kappa-bifenthrin+SX,kinoprene+SX, lambda-cyhalothrin+SX, lepimectin+SX, lime sulfur+SX,lufenuron+SX, machine oil+SX, malathion+SX, mecarbam+SX,meperfluthrin+SX, metafiumizone+SX, metam+SX, methamidophos+SX,methidathion+SX, methiocarb+SX, methomyl+SX, methoprene+SX,methoxychlor+SX, methoxyfenozide+SX, methyl bromide+SX, metofluthrin+SX,metolcarb+SX, metoxadiazone+SX, mevinphos+SX, milbemectin+SX, milbemycinoxime+SX, momfluorothrin+SX, monocrotophos+SX, moxidectin+SX, naled+SX,neem oil+SX, nicotine+SX, nicotine-sulfate+SX, nitenpyram+SX,novalurori+SX, noviflumuron+SX, oil of the seeds of Chenopodiumanthelminticum+SX, omethoate+SX, oxamyl+SX, oxydemeton-methyl+SX,parathion+SX, parathion-methyl+SX, permethrin+SX, phenothrin+SX,phenthoate+SX, phorate+SX, phosalone+SX, phosmet+SX, phosphamidon SX,phosphine+SX, phoxim+SX, pirimicarb+SX, pirimiphos-methyl+SX, potassiumcyanide+SX, prallethrin+SX, profenofos+SX, profluthr+SX, propargite+SX,propetamphos+SX, propoxur+SX, propylene glycol alginate+SX,prothiofos+SX, pyflubumide+SX, pymetrozine+SX, pyraclofos+SX,pyrethrins+SX, pyridaben+SX, pyridalyl+SX, pyridaphenthion+SX,pyrifluquinazone+SX, pyrimidifen+SX, pyriminostrobin+SX, pyriprole+SX,pyriproxyfen+SX, quinalphos+SX, resmethrin+SX, rotenone+SX,ryanodine+SX, selamactin+SX, sigma-cypermethrin+SX, silafluofen+SX,sodium borate+SX, sodium cyanide+SX, sodium metaborate+SX,spinetoram+SX, spinosad+SX, spirodiclofen+SX, spiromesifen+SX,spiropidion+SX, spirotetramat+SX, sulfluramid+SX, sulfotep+SX,sulfoxaflor+SX, sulfur+SX, sulfuryl fluoride+SX, tartar emetic+SX,tau-fluvalinate SX, tebufenozide+SX, tebufenpyrad+SX, tebupirimfos+SX,teflubenzuron+SX, tefluthrin+SX, temephos SX, terbufos+SX, terpeneconstituents of the extract of Chenopodium ambrosioides nearambrosioides, Brand name: Terpenoid blend QRD 460+SX,tetrachlorvinphos+SX, tetradifon+SX, tetramethrin+SX,tetramethylfluthrin+SX, tetraniliprole+SX, theta-cypermethrin+SX,thiacloprid+SX, thiamethoxam+SX, thiocyclam+SX, thiodicarb+SX,thiofanox+SX, thiometon+SX, thiosultap-disodium+SX,thiosultap-monosodium+SX, tioxazafen+SX, tolfenpyrad+SX,tralomethrin+SX, transfluthrin+SX, triazamate+SX, triazophos+SX,trichlorfon+SX, triflumezopyrim+SX, triflumuron+SX, trimethacarb+SX,vamidothion+SX, XMC (3,5-dimethylphenya N-methylcarbamate)+SX,xylylcarb+SX, zeta-cypermethrin+SX, zinc phosphide+SX,(E)-N-{1-[(6-chloropyridin-3-yl)methyl]pyridin-2(1H)-ylidene}-2,2,trifluoroacetamide (1689566-03-7)+SX,3-bromo-N-[2,4-dichloro-6-(methylcarbamoyl)phenyl]-1-(3,5-dichloropyridin-2-yl)-1H-pyrazole-5-carboxamide(1104384-14-6)+SX,N-[3-chloro-1-(pyridin-3-yl)-1H-pyrazol-4-yl]-N-ethyl-3-(3,3,3-trifluoropropylsulfanyl)propanamide(1477919-27-9)+SX,N-[3-chloro-1-(pyridin-3-yl)-1H-pyrazol-4-yl]-N-ethyl-3-(3,3,3-trifluorapropanesulfinyl)propanamide(1477923-37-7)+SX,2-[(ethanesulfonyl)pyridin-2-yl]-5-(trifluoromethanesulfonyl)benzoxazole(1616678-32-0)+SX,4-[5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4,5-dihydro-1,2-oxazol-3-yl]-2-methyl-N-(1-oxothiethan-3-yl)benzamide(1241050-20-3)+SX,3-methoxy-N-(5-{5-(trifluoromethyl)-5-[3-(trifluoromethyl)phenyl]-4,5-dihydro-1,2-oxazol-3-yl}indan-1-yl)propanamide (1118626-57-5)+SX,N-[2-bromo-6-chloro-4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)phenyl]-3-{ethyl[(pyridin-4-yl)carbonyl]amino}-2-methoxybenzamide(1429513-53-0)+SX,N-[2-bromo-6-chloro-4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)phenyl]-3-[ethyl(4-cyanobenzoyl)amino]-2-methoxybenzamide(1609007-65-9)+SX,N-[2-bromo-6-difluoromethoxy-4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)phenyl]-3-{methyl[(pyridin-4-yl)carbonyl]amino}-2-methoxybenzamide(1630969-78-6)+SX,1-{2-fluoro-4-methyl-5-[(2,2,2-trifluoroethyl)sulfinyl]phenyl}-3-(trifluoromethyl)-1H-1,2,4-triazole-5-amine(885026-50-6)+SX, BT crop protein Cry1Ab+SX, BT crop protein Cry1Ac+SX,BT crop protein Cry1Fa+SX, BT crop protein Cry1A.105+SX, BT crop proteinCry2Ab+SX, BT crop protein Vip3A+SX, BT crop protein Cry3A+SX, BT cropprotein Cry3Ab+SX, BT crop protein Cry3Bb+SX, BT crop proteinCry34Ab1/Cry35Ab1+SX, Adoxophyes orana granulosis virus+SX, Anticarsiagemmatalis mNPV+SX, Autographa californica mNPV FV#11+SX, Cydiapomonella GV V15+SX, Cydia pomonella GV V22+SX, Cryptophlebia leucotretaGV+SX, Dendrolimus punctatus cypovirus+SX Helicorerpa armigera NPVBV-0003+SX, Helicoverpa zea NPV+SX, Lymantria dispar NPV+SX, Mamestrabrassicae NPV+SX, Mamestra configurator NPV+SX, Neodiprion abietisNPV+SX, Neodiprion lecontei NPV+SX, Neodiprion sertifer NPV+SX, Nosemalocustae+SX, Orgyia pseudotsugata NPV+SX, Pieris rapae GV+SX, Plodiainterpunctella GV+SX, Spodoptera exigua mNPV+SX, Spodoptera littoralismNPV+SX, Spodoptera litura NPV+SX, Arthrobotrys dactyloides+SX, Bacillusfirmus GB-126+SX, Bacillus firmus I-1582+SX, Bacillus megaterium+SX,Bacillus sp. AQ175+SX, Bacillus sp. AQ177+SX, Bacillus sp. AQ178+SX,Bacillus sphaericus 2362+SX, Bacillus sphaericus ABTS1743+SX, Bacillussphaericus Serotype H-5a5b+SX, Bacillus thuringiensis AQ52+SX, Bacillusthuringiensis BD#32+SX, Bacillus thuringiensis CR-371+SX, Bacillusthuringiensis subsp. Aizawai BTS-1857+SX, Bacillus thuringiensis subsp.Aizawai AM65-52+SX, Bacillus thuringiensis subsp. Aizawai GC-91+SX,Bacillus thuringiensis subsp. Aizawai Serotype H-7+SX, Bacillusthuringiensis subsp. Kurstaki ABTS351+SX, Bacillus thuringiensis subsp.Kurstaki BMP123+SX, Bacillus thuringiensis subsp. Kurstaki EG234+SX,Bacillus thuringiensis subsp. Kurstaki EG7841+SX, Bacillus thuringiensissubsp. Kurstaki EVB113-19+SX, Bacillus thuringiensis subsp. KurstakiF10+SX, Bacillus thuringiensis subsp. Kurstaki HD-1+SX, Bacillusthuringiensis subsp. Kurstaki PB54+SX, Bacillus thuringiensis subsp.Kurstaki SA-11+SX, Bacillus thuringiensis subsp. Kurstaki SA-12+SX,Bacillus thuringiensis subsp. Tenebriosis NB176+SX, Bacillusthuringiensis subsp. Thuringiensis MPPL002+SX, Bacillus thuringiensissubsp. morrisoni+SX, Bacillus thuringiensis var. colmeri+SX, Bacillusthuringiensis var. darmstadiensis 24-91+SX, Bacillus thuringiensis var.dendrolimus+SX, Bacillus thuringiensis var. galleriae+SX, Bacillusthuringiensis var. israelensis BMP144+SX, Bacillus thuringiensis var.israelensis serotype H-11+SX, Bacillus thuringiensis var. japonensisbuibui+SX, Bacillus thuringiensis var. san diego M-7+SX, Bacillusthuringiensis var. 7216+SX, Bacillus thuringiensis var. aegypti+SX,Bacillus thuringiensis var. T36+SX, Beauveria bassiana ANT-03+SX,Beauveria bassiana ATCC74040+SX, Beauveria bassisana GHA+SX, Beauveriabrongniartii+SX, Burkholderia rinojensis A396+SX, Chromobacteriumsubtsugae PRAA4-1T+SX, Dactyllela ellipsospora+SX, Dectylariathaumasia+SX, Hirsutella minnesotensis+SX, Hirsutella rhossiliensis+SX,Hirsutella thompsonii+SX, Lagenidium giganteum+SX, Lecanicillium lecaniiKV01+SX, Lecanicillium lecanii conidia of strain DAOM198499+SX,Lecanicillium lecanii conidia of strain DAOM216596+SX, Metarhiziumanisopliae F52+SX, Metarhizium anisopliae var. acridum+SX, Metarhiziumflavoviride+SX, Monacrosporium phymatopagum+SX, Paecilomycesfumosoroseus Apopka97+SX, Paecilomyces lilacinus 251+SX, Paecilomycestenuipes T1+SX, Paenibacillus popilliae+SX, Pasteuria nishizawae Pn1+SX,Pasteuria penetrans+SX, Pasteuria usgae+SX, Pasteuria thoynei+SX,Serratia entomophila+SX, Verticillium chlamydosporium+SX, Verticilliumlecani NCIM1312+SX, lenoremycin+SX, concanamycin A+SX

Combination of the Present ingredient of the above Group (b) and thePresent compound Z:

acibenzolar-S-methyl+SX, aldimorph+SX, ametoctradin+SX, aminopyrifen+SX,amisulbrom+SX, anilazine+SX, azaconazole+SX, azoxystrobin+SX, basiccopper sulfate+SX, benalaxyl+SX, benalaxyl-M+SX, benodanil+SX,benomyl+SX, benthiavalicarb+SX, benthivalicarb-isopropyl+SX,benzovindiflupyr+SX, binapacryl+SX, biphenyl+SX, bitertanol+SX,bixafen+SX, blasticidin-S+SX, Bordeaux mixture+SX, boscalid+SX,bromothalonil+SX, bromuconazole+SX, bupirimate+SX, captafol+SX,captan+SX, carbendazim+SX, carboxin+SX, carpropamid+SX,chinomethionat+SX, chitin+SX, chioroneb+SX, chlorothalonil+SX,chlozolinate+SX, colletochlorin B+SX, copper(II) acetate+SX, copper(II)hydroxide+SX, copper oxychloride SX, copper(II) sulfate+SX,coumoxystrobin+SX, cyazofamid+SX, cyflufenamid+SX, cymoxanil+SX,cyproconazole+SX, cyprodinil+SX, dichlobentiazox+SX, dichlofluanid+SX,diclocymet+SX, diclomezine+SX, dicloran+SX, diethofencarb+SX,difenoconazole+SX, diflumetorim+SX, imethachlone+SX, dimethirimol+SX,dimethomorph+SX, dimoxystrobin+SX, diniconazole+SX, diniconazole-M+SX,dinocap SX, dipotassium hydrogenphosphite+SX, dipymetitrone+SX,dithianon+SX, dodecylbenzenesulphonic acid bisethylenediamine copper(II)salt+SX, dodemorph+SX, iodine+SX, edifenphos+SX, enoxastrobin+SX,epoxiconazole+SX, etaconazole+SX, ethaboxam+SX, ethirimol+SX,etridiazole+SX, extract from Melaleuca alternifolia+SX, extract fromReynoutria sachalinensis+SX, extract from the cotyledons of lupineplantlets (“BLAD”)+SX, extract of Allium sativum+SX, extract ofEauisetum arvense+SX, extract of Tropaeolum majus+SX, famoxadone+SX,fenamidone+SX, fenaminstrobin+SX, fenarimol+SX, fenbuconazole+SX,fenfuram SX, fenhexamid+SX, fenoxanil+SX, fenpiclonil+SX,fenpicoxamid+SX, fenpropidin+SX, fenpropimorph+SX, fenpyrazamine+SX,fentin acetate+SX, fentin chloride+SX, fentin hydroxide+SX, ferbam+SX,ferimzone+SX, florylpicoxamid+SX, fluazinam+SX, fludioxonil+SX,flufenoxystrobin+SX, fluindapyr+SX, flumorph+SX, fluopicolide+SX,fluopimomide+SX, fluoroimide+SX, fluoxastrobin+SX, fluquinconazole+SX,flusilazole+SX, flusulfamide+SX, flutianil+SX, flutolanil+SX,flutriafol+SX, fluxapyroxad+SX, folpet+SX, fosetyl+SX,fosetyl-aluminium+SX, fuberidazole+SX, furalaxyl+SX, furametpyr+SX,guazatine+SX, hexaconazole+SX, hyinexazole+SX, imazalil+SX,imibenconazole+SX, iminoctadine+SX, iminoctadine triacetate+SX,inpyrfluxam+SX, iodocarb+SX, ipconazole+SX, ipfentrifluconazole+SX,ipflufenoquin+SX, iprobenfos+SX, iprodione+SX, iprovalicarb+SX,isofetamid+SX, sofiucypram+SX, isoprothiolane+SX, isopyrazam+SX,isotianil+SX, kasugamycin+SX, kresoxim-methyl+SX, laminarin+SX, leavesand bark of Quercus+SX, mancozeb+SX, mandestrobin+SX, mandipropamid+SX,maneb+SX, mefentrifluconazole+SX, mepanipyrim+SX, mepronil+SX,meptyldinocap+SX, metalaxyl+SX, metalaxyl-M+SX, metconazole+SX,methasulfocarb+SX, metiram+SX, metominostrobin+SX, metrafenone+SX,mineral oils+SX, myclobutanil+SX, naftifine+SX, nuarimol+SX,octhilinone+SX, ofurace+SX, orysastrobin+SX, oxadixyl+SX,oxathiapiprolin+SX, oxine-copper+SX, oxolinic acid+SX, oxpoconazole+SX,oxpoconazole fumarate+SX, oxycarboxin+SX, oxytetracycline+SX,pefurazoate+SX, penconazole+SX, pencycuron+SX, penflufen+SX,penthiopyrad+SX, phenamacril+SX, phosphorous acid+SX, phthalide+SX,picarbutrazox+SX, picoxystrobin+SX, piperalin+SX, polyoxins+SX,potassium hydrogencarbonate+SX, potassium dihydrogenphosphite+SX,probenazole+SX, prochloraz+SX, procymidone+SX, propamidine+SX,propamocarb+SX, propiconazole SX, propineb+SX, proquinazid+SX,prothiocarb+SX, prothioconazole+SX, pydiflumetofen+SX,pyraclostrobin+SX, pyrametostrobin+SX, pyraoxystrobin+SX,pyrapropoyne+SX, pyraziflumid+SX, pyrazophos+SX, pyribencarb+SX,pyributicarb+SX, pyrifenox+SX, pyrimethanil+SX, pyrimorph+SX,pyriofenone+SX, pyrisoxazole+SX, pyroquilon+SX, Quillaja extract+SX,guinconazole+SX, quinofumelin+SX, quinoxyfen+SX, quintozene+SX, Saponinsof Chenopodium quinoa+SX, sedaxane+SX, silthiofam+SX, simeconazole+SX,sodium hydrogencarbonate+SX, spiroxamine+SX, streptomycin+SX, sulfur+SX,tebuconazole+SX, tebufloquin+SX, teclofthalam+SX, tecnazene+SX,terbinafine+SX, tetraconazole+SX, thiabendazole+SX, thifluzamide+SX,thiophanate+SX, thiophanate-methyl+SX, thiram+SX, thymol+SX,tiadinil+SX, tolclofos-methyl+SX, tolfenpyrad+SX, tolprocarb+SX,tolylfluanid+SX, triadimefon+SX, triadirnenol+SX, triazoxide+SX,triclopyricarb+SX, tricyclazole+SX, tridemorph+SX, trifloxystrobin+SX,triflumizole+SX, triforine+SX, triticonazole+SX, validamycin+SX,valifenalate+SX, vinclozolin+SX, yellow mustard powder+SX, zincthiazole+SX, zineb+SX, ziram+SX, zoxamide+SX,3-difluoromethyl-N-methoxy-1-methyl-N-[(1R)-1-methyl-2-(2,4,6-trichlorophenyl)ethyl]pyrazol-4-carboxamide(1639015-48-7)+SX,3-difluoromethyl-N-methoxy-1-methyl-N-[(1S)-1-methyl-2-(2,4,6-trichlorophenyl)ethyl]pyrazol-4-carboxamide(1639015-49-8)+SX,3-difluoromethyl-1-methyl-N-(1,1,3-trimethylindan-4-yl)pyrazole-4-carboxamide(141573-94-6)+SX,3-difluoromethyl-N-[(3R)-7-fluoro-1,1,3-trimethylindan-4-yl]-1-methylpyrazole-4-carboxamide(1513466-73-3)+SX,3-chloro-5-phenyl-6-methyl-4-(2,6-difluorophenyl)pyridazine(1358061-55-8)+SX,N′-[4-({3-[(4-chlorophenyl)methyl]-1,2,4-thiadiazol-5-yl}oxy-2,5-dimethylphenyl]-N-ethyl-N-methylmethaneimidamide(1202781-91-6+SX,2-{3-[2-(1-{[3,5-bis(difluoromethyl)-1H-pyrazol-1-yl]acetyl}piperidin-4-yl)-1,3-thiazol-4-yl]-4,5-dihydro-1,2-oxazol-5-yl}-3-chlorophenyl=methanesulfonate(1360819-11-9)+SX,4-(2-bromo-4-fluorophenyl)-N-(2-chloro-6-fluorophenyl)-1,3-dimethyl-1H-pyrazole-5-amine(1362477-26-6)+SX,2,2-dimethyl-9-fluoro-5-(quinolin-3-yl)-2,3-dihydrobenzo[f][1,4]oxazepine (1207749-50-5+SX,2-[6-(3-fluoro-4-methoxyphenyl)-5-methylpyridin-2-yl]quinazoline(1257056-97-5)+SX,5-fluoro-2-[(4-methylphenyl)methoxy]-4-pyrimidineamine(1174376-25-0)+SX,5-fluoro-4-imino-3-methyl-1-tosyl-3,4-dihydropyrimidine-2(1H)-one(1616664-98-2)+SX,N′-(2,5-dimethyl-4-phenoxyphenyl)-N-ethyl-N-methyl-methaneimidamide(1052688-31-9)+SX,N′-{4-[(4,5-dichlorothiazol-2-yl)oxy]-2,5-dimethylphenyl}-N-ethyl-N-methyl-methaneimidamide(929908-57-6)+SX, ethyl (2Z)-3-amino-2-cyano-3-phenylacrylate(39491-78-6)+SX,N-{(2-chlorothiazol-5-yl)methyl}-N-ethyl-6-methoxy-3-nitropyridine-2-amine(1446247-98-8)+SX,1-[2-({[1-(4-chlorophenyl)-1H-pyrazol-3-yl]oxy}methyl)-3-methylphenyl]-4-methyl-5-oxo-4,5-dihydro-1H-tetrazole(1472649-01-6)+SX,α-[3-(4-chloro-2-fluorophenyl)-5-(2,4-difluorophenyl)-4-isoxazolyl]-3-pyridinemethanol (1229605-96-2)+SX,(αS)-[3-(4-chloro-2-fluorophenyl)-5-(2,4-difluorophenyl)-4-isoxazolyl]-3-pyridinemethanol (1229606-46-5)+SX,(αS)-[3-(4-chloro-2-fluorophenyl)-5-(2,4-difluorophenyl)-4-isoxazolyl]-3-pyridinemethanol (1229606-46-5)+SX), (αR)-[3-(4-chloro-2-fluorophenyl)-5-(2,4-difluorophenyl)-4-isoxazolyl]-3-pyridine methanol(1229606-02-3)+SX),2-{[3-(2-chlorophenyl)-2-(2,4-difluorophenyl)oxiran-2-yl]methyl}-2,4-dihydro-3H-1,2,4-triazole-3-thione(1342260-19-8)+SX,2-{[(2R,3S)-3-(2-chlorophenyl)-2-(2,4-difluorophenyl)oxiran-2-yl]methyl}-2,4-dihydro-3H-1,2,4-triazole-3-thione(1638897-70-7)+SX,2-{[(2S,3R)-3-(2-chlorophenyl)-2-(2,4-difluorophenyl)oxiran-2-yl]methyl}-2,4-dihydro-3H-1,2,4-triazole-3-thione(1638897-71-8)+SX,2-{[(2R,3R)-3-(2-chlorophenyl)-2-(2,4-difluorophenyl)oxiran-2-yl]methyl}-2,4-dihydro-3H-1,2,4-triazole-3-thione(1638897-72-9)+SX,2-{[(2S,3S)-3-(2-chlorophenyl)-2-(2,4-difluorophenyl)oxiran-2-yl]methyl}-2,4-dihydro-3H-1,2,4-triazole-3-thione(1638897-73-0)+SX,1-{[3-(2-chlorophenyl)-2-(2,4-difluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazol-5-ylthiocyanate (1342260-26-7)+SX,1-{[(2R,3S)-3-(2-chlorophenyl)-2-(2,4-difluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazol-5-ylthiocyanate (1638897-82-1)+SX,1-{[(2S,3R)-3-(2-chlorophenyl)-2-(2,4-difluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazol-5-ylthiocyanate (1638897-84-3)+SX,1-{[(2R,3R)-3-(2-chlorophenyl)-2-(2,4-difluorophenyl)oxian-2-yl]methyl}-1H-1,2,4-triazol-5-ylthiocyanate (1638897-86-5)+SX,1-{[(2S,3S)-3-(2-chlorophenyl)-2-(2,4-difluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazol-5-ylthiocyanate (1638897-89-8)+SX,5-(4-chlorobenzyl)-2-chloromethyl-2-methyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol(1394057-11-4)+SX,(1R,2S,5S)-5-(4-chlorobenzyl)-2-chloromethyl-2-methyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopenotanol(1801930-06-2)+SX,(1S,2R,5R)-(4-chlorobenzyl)-2-chloromethyl-2-methyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol(1801930-07-3)+SX,(1R,2R,5R)-5-(4-chlorobenzyl)-2-chloromethyl-2-methyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol(1801919-53-8)+SX,(1S,2S,5S)-5-(4-chlorobenzyl)-2-chloromethyl-2-methyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol(1801919-54-9)+SX,(1R,2R,5S)-(4-chlorobenzyl)-2-chloromethyl-2-methyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol(1801919-55-0)+SX,(1S,2R,5R)-5-(4-chlorobenzyl)-2-chloromethyl-2-methyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol(1801919-56-1)+SX,(1R,2S,5R)-5-(4-chlorobenzyl)-2-chloromethyl-2-methyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol(1801919-57-2)+SX,(1S,2R,5S)-5-(4-chlorobenzyl)-2-chloromethyl-2-methyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol(1801919-58-3)+SX,Methyl=3-[4-(chlorophenyl)methyl]-2-hydroxy-1-methyl-2-(1H-1,2,4,-triazol-1-ylmethyl)cyclopentanecarboxylate (1791398-02-1)+SX,Methyl=(1R,2S,3S)-3-[(4-chlorophenyl)methyl]-2-hydroxy-1-methyl-2-(1H-1,2,4-triazol-1-ylethyl)cyclopentane carboxylate+SX,Methyl=(1S,2R,3R)-3-[(4-chlorophenyl)methyl]-2-hydroxy-1-methyl-2-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanecarboxylate+SX,Methyl=(1R,2R,3R)-3-[(4-chlorophenyl)methyl]-2-hydroxy-1-methyl-2-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanecarboxylate+SX,Methyl=(1S,2S,3S)-3-[(4-chlorophehyl)methyl]-2-hydroxy-1-methyl-2-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanecarboxylate+SX,Methyl=(1R,2R,3S)-3-[(4-chlorophenyl)methyl]-2-hydroxy-1-methyl-2-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanecarboxylate+SX,Methyl=(1S,2S,3R)-3-[(4-chlorophenyl)methyl]-2-hydroxy-1-methyl-2-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanecarboxylate+SX,Methyl=(1R,2S,3R)-3-[(4-chlorophenyl)methyl]-2-hydroxy-1-methyl-2-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanecarboxylate+SX,Methyl=(1S,2R,3S)-3-[(4-chlorophenyl)methyl]-2-hydroxy-1-methyl-2-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanecarboxylate+SX,2-chloromethyl-5-(4-fluorobenzyl)-2-methyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol(1394057-13-6)+SX,(1R,2S,5S)-2-chloromethyl-5-(4-fluorobenzyl)-2-methyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol(1301930-08-4)+SX,(1S,2R,5R)-2-chloromethyl-5-(4-fluorobenzyl)-2-methyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol(1801930-09-5)+SX,(1R,2R,5R)-2-chloromethyl-5-(4-fluorobenzyl)-2-methyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol(1638898-08-4)+SX,(1S,2S,5S)-2-chloromethyl-5-(4-fluorobenzyl)-2-methyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol(1638898-10-8)+SX,(1R,2R,5S)-2-chloromethyl-5-(4-fluorobenzyl)-2-methyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol(1638898-13-1)+SX,(1S,2S,5R)-2-chloromethyl-5-(4-fluorobenzyl)-2-methyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol(1638898-16-4)+SX, (1R,2S,5R)-2-chloromethyl-5-(4-fluorobenzyl)-2-methyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol(1638898-20-0)+SX,(1S,2R,5S)-2-chloromethyl-5-(4-fluorobenzyl)-2-methyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol(1638898-24-4)+SX,(R)-2-[2-chloro-4-(4-chlorophenoxy)phenyl]-1-(1,2,4-triazol-1-yl)pent-3-yne-2-ol(1801919-59-4)+SX,(R)-2-[4-(4-chlorophenoxy)-2-(trifluoromethyl)phenyl]-1-(1,2,4-triazol-1-yl)propane-2-ol(1616236-94-2)+SX,(R)-1-[4-(4-chlorophenoxy)-2-(trifluoromethyl)phenyl]-1-cyclopropyl-2-(1,2,4-triazol-1-yl)ethanol(1801919-60-7)+SX,(R)-2-[4-(4-chlorophenoxy)-2-(trifluoromethyl)phenyl]-3-methyl-1-(1,2,4-triazol-1-yl)butane-2-ol(1801919-61-8)+SX,3-[5-(4-chlorophenyl)-2,3-dimethyl-1,2-oxazolydin-3-yl]pyridine(847749-37-5)+SX, Agrobacterium radiobactor K1025+SX, Agrobacteriumradiobactor K84+SX, Bacillus amyloliquefaciens AT332+SX, Bacillusamyloliquefaciens B3+SX, Bacillus amyloliquefaciens D747+SX, Bacillusamyloliquefaciens DB101+SX, Bacillus amyloliquefaciens DB102+SX,Bacillus amyloliquefaciens GB03+SX, Bacillus amyloliquefaciens FZB24+SX,Bacillus amyloliquefaciens FZB42+SX, Bacillus amyloliquefaciensIN937a+SX, Bacillus amyloliquefaciens MBI600+SX, Bacillusamyloliquefaciens QST713+SX, Bacillus amyloliquefaciens isolate B246+SX,Bacillus amyloliquefaciens F727+SX, Bacillus licheniformis HB-2+SX,Bacillus licheniformis SD3086+SX, Bacillus pumilus AQ717+SX, Bacilluspumulis BUF-33+SX, Bacillus pumulis GB34+SX, Bacillus pumulisQST2808+SX, Bacillus simplex CGF2856+SX, Bacillus subtilis AQ153+SX,Bacillus subtilis AQ743+SX, Bacillus subtilis BU1814+SX, Bacillussubtilis D747+SX, Bacillus subtilis DB101+SX, Bacillus subtilisFZB24+SX, Bacillus subtilis GB03+SX, Bacillus subtilis HAI0404+SX,Bacillus subtilis IAB/BS03+SX, Bacillus subtilis MBI600 SX, Bacillussubtilis QST30002/AQ30002+SX, Bacillus subtilis QST30004/AQ30004+SX,Bacillus subtilis QST713+SX, Bacillus subtilis QST714+SX, Bacillussubtilis var. Amyloliquefaciens FZB24+SX, Bacillus subtilis Y1336+SX,Burkholderia cepacia+SX, Burkholderia cepacia type Wisconsin J82+SX,Burkholderia cepacia type Wisconsin M54+SX, Candida oleophilaO+SX,Candida saitoana+SX, Chaetomium cupreum+SX, Clonostayhys rosea+SX,Coniothyrium minitans CGMCC8325+SX, Coniothyrium minitans CON/M/91-8+SX,Cryptococcus albidus+SX, Erwinia carotovora subsp. carotovoraCGE234M403+SX, Fusarium oxysporum Fo47+SX, Gliocladium catenulatumJ1446+SX, Paenibacillus polymyxa AC-1+SX, Paenibacillus polymyxaBS-0105+SX, Pantoea agglomerans E325+SX, Phlebiopsis giganteaVRA1992+SX, Pseudomonas aureofaciens TX-1+SX, Pseudomonas chlororaphis63-28+SX, Pseudomonas chlororaphis MA342+SX, Pseudomonas fluorescens1629RS+SX, Pseudomonas fluorescens A506+SX, Pseudomonas fluorescensCL145A+SX, Pseudomonas fluorescens G7090+SX, Pseudomonas sp. CAB-02+SX,Pseudomonas syringae 742RS+SX, Pseudomonas syringae MA-4+SX, Pseudozymaflocculosa PF-A22UL+SX, Pseudomonas rhodesiae HAI-0604+SX, Pythiumoligandrum DV74+SX, Streptomyces griseoviridis K61+SX, Streptomyceslydicus WYCD108US+SX, Streptomyces lydicus WYEC108+SX, Talaromycesflavus SAY-Y-94-01+SX, Talaromyces flavus V117b+SX, Trichodermaasperellum ICC012+SX, Trichoderma asperellum SKT-1+SX, Trichodermaasperellum T34+SX, Trichoderma atroviride CNCM 1-1237+SX, Trichodermaatroviride LC52+SX, Trichoderma atroviride SCI+SX, Trichodermaatroviride SKT-1+SX, Trichoderma gamsii ICC080+SX, Trichoderma harzianum21+SX, Trichoderma harzianum DB104+SX, Trichoderma harzianum DSM14944+SX, Trichoderma harzianum ESALQ-1303+SX, Trichoderma harzianumESALQ-1306+SX, Trichoderma harzianum IIHR-Th-2+SX, Trichodermaharzianum+SX, Trichoderma harzianum MO1+SX, Trichoderma harzianum SF+SX,Trichoderma harzianum T22+SX, Trichoderma harzianum T39+SX, Trichodermaharzianum TEM908+SX, Trichoderma harzianum TH35+SX, Trichodermapolysporm IM1206039+SX, Trichoderma stromaticum+SX, Trichoderma virensG-41+SX, Trichoderma virens GL-21+SX, Trichoderma viride+SX, Variovoraxparadoxus CGF4526+SX, and Harpin protein+SX.

Combination of the Present ingredient of the above Group (c) and thePresent compound Z:

1-methylcyclopropene+SX, 2,3,5-triiodobenzoic acid+SX, IAA((1H-indol-3-yl)acetic acid)+SX, IBA (4-(1H-indol-3-yl)butyric acid)+SX,MCPA (2-(4-chloro-2-methylphenoxy)acetic acid)+SX, MCPB(4-(4-chloro-2-methylphenoxy)butyric acid)+SX, 4-CPA(4-chlorophenoxyacetic acid)+SX, 5-aminolevulinic acid hydrochloride+SX,6-benzylaminopurine+SX, abscisic acid+SX, AVG(aminoethoxyvinylglycine)+SX, ancymidol+SX, butralin+SX, calciumcarbonate+SX, calcium chloride+SX, calcium formate+SX, calciumperoxide+SX, calcium polysulfide+SX, calcium sulfate+SX,chlormequat-chloride+SX, chlorpropham+SX, choline chloride+SX,cloprop+SX, cyanamide+SX, cyclanilide+SX, daminozide+SX, decan-1-ol+SX,dichlorprop+SX, dikegulac+SX, dimethipin+SX, diquat+SX, ethephon+SX,ethychlozate+SX, flumetralin+SX, flurprimidol+SX, forchlorfenuron+SX,Gibberellin A+SX, Gibberellin A3+SX, inabenfide+SX, Kinetin+SX, maleichydrazide+SX, mefluidide+SX, mepiquat-chloride+SX, oxidizedglutathione+SX, pacrobutrazol+SX, pendimethalin+SX,prohexandione-calcium+SX, prohydrojasmon+SX, pyraflufen-ethyl+SX,sintofen+SX, sodium 1-naphthaleneacetate+SX, sodium cyanate+SX,streptmycin+SX, thidiazuron+SX, triapenthenol+SX, Tributos+SX,trinexapac-ethyl+SX, uniconazole-P+SX, 2-(naphthalene-1-yl)acetamide+SX,[4-oxo-4-(2-phenyethyl)amino]butyric acid+SX, Methyl5-(trifluoromethyl)benzo[b]thiophen-2-carboxylate+SX,3-[(6-chloro-4-phenylquinazolin-2-yl)amino]-1-propanol+SX,formononetin+SX, Glomus spp.+SX, Glomus intraradices+SX, Glomusmosseae+SX, Glomus aggregatum+SX, Glomus etunicatum+SX, Bradyrhizobiumelkani+SX, Bradyrhizobium japonicum+SX, Bradyrhizobium lupini+SX,Rhizobium leguminosarum bv. trifolii+SX, Rhizobium leguminosarum bv.phaseoli+SX, Rhizobium leguminosarum bv. viciae+SX, Sinorhizobiummeliloti+SX, Rhizobium spp.+SX, Rhizobium fredii+SX, Rhizobium loti+SX,Rhizobium trifolii+SX, Rhizobium tropici+SX, 1,3-diphenylurea+SX,Claroideoglomus etunicatum+SX, Funneliformis mosseae+SX, Gigasporamargarita+SX, Gigaspora rosea+SX, Glomus aggregatum+SX, Glomusdeserticola+SX, Glomus monosporum+SX, Paraglomus brasillianum+SX,Rhizophagus clarus+SX, Rhizophagus intraradices RTI-801+SX, Rhizophagusirregularis DACM 197198+SX, Azorhizobium caulinodans+SX, Azospirillumamazonense+SX, Azospirillum brasilense XOH+SX, Azospirillum brasilenseAb-V5+SX, Azospirillum brasilense Ab-V6+SX, Azospirillum caulinodans+SX,Azospirillum halopraeferens+SX, Azospirillum irakense+SX, Azospirillumlipoferum+SX, Bradyrhizobium elkanii SEMIA 587+SX, Bradyrhizobiumelkanii SEMIA 5019+SX, Bradyrhizobium japonicum TA-11+SX, Bradyrhizobiumjaponicum USDA 110+SX, Bradyrhizobium liaoningense+SX, Bradyrhizobiumlupini+SX, Delftia acidovorans RAY209+SX, Mesorhizobium ciceri+SX,Mesorhizobium huakii+SX, Mesorhizobium loti+SX, Rhizobium etli+SX,Rhizobium galegae+SX, Rhizobium leguminosarum bv. Phaseoli+SX, Rhizobiumleguminosarum bv. Trifolii+SX, Rhizobium leguminosarum bv. Viciae+SX,Rhizobium tropici+SX, Sinorhizobium fredii+SX, and Sinorhizobiummeliloti+SX

Combination of the Present ingredient of the above Group (d) and thePresent compound Z:

allidochlor+SX, benoxacor+SX, cloquintocet+SX, cloquintocet-mexyl+SX,cyometrinil+SX, cyprosulfamide+SX, dichlormid+SX, dicyclonone+SX,dimepiperate+SX, disulfoton+SX, dymron+SX, fenchlorazole+SX,fenchlorazole-ethyl+SX, fenclorim+SX, flurazole+SX, furilazole+SX,fluxofenim+SX, Hexim+SX, isoxadifen+SX, isoxadifen-ethyl+SX,mecoprop+SX, mefenpyr+SX, mefenpyr-ethyl+SX, mefenpyr-diethyl+SX,mephenate+SX, metcamifen+SX, oxabetrinil+SX, 1,8-naphthalicanhydride+SX, 1,8-octamethylene diamine+SX, AD-67(4-(dicloroacetyl)-1-oxa-4-azaspiro[4.5]decane)+SX, CL-304415(4-carboxy-3,4-dihydro-2H-1-benzopyran-4-acetic acid)+SX, CSB(1-bromo-4-[(chloromethyl)sulfonyl]benzene)+SX, DKA-24(2,2-dichloro-N-[2-oxo-2-(2-propenylamino)ethyl]-N-(2-propenyl)acetamide)+SX,MG191 (2-(dichloromethyl)-2-methyl-1,3-dioxolane)+SX, MG-838 (2-propenyl1-oxa-4-azaspiro[4,5]decane-4-carbodithioate)+SX, PPG-1292(2,2-dichloro-N-(1,3-dioxan-2-ylmethyl)-N-(2-propenyl)acetamide)+SX,R-28725 (3-(dichloroacetyl)-2,2-dimethyl-1,3-oxazolidine)+SX, R-29148(3-(dichloroacetyl)-2,2,5-trimethyl-1,3-oxazolidine)+SX, and TI-35(1-(dichloroacetyl)azepane)+SX.

Combination of the Present ingredient of the above Group (e) and thePresent compound Z:

1-dodecyl-1H-imidazole+SX,N-(2-ethylhexyl)-8,9,10-trinorborn-5-ene-2,3-dicarboximide+SX,bucarpolate+SX, N,N-dibutyl-4-chlorobenzenesulfonamide+SX,dietholate+SX, diethylmaleate+SX, piperonyl butoxide+SX, piperonylcyclonene+SX, piprotal+SX, propyl isome+SX, safroxan+SX, sesamex+SX,sesamolin+SX, sulfoxide+SX, Verbutin+SX, DMC(1,1-bis(4-chlorophenyl)ethanol)+SX, FDMC(1,1-bis(4-chlorophenyl)-2,2,2-trifluoroethanol)+SX, ETN(1,2-epoxy-1,2,3,4-tetrahydronaphthalene)+SX, ETP(1,1,1-trichloro-2,3-expoxypropane)+SX, PSCP (phenylsaligenin cyclicphosphate)+SX, TBPT (S,S,S-tributyl phosphorotrithioate)+SX, and TPP(triphenyl phosphate)+SX.

Combination of the Present ingredient of the above Group (f) and thePresent compound Z:

anthraquinone+SX, chloralose+SX, acrep+SX, butopyronoxyl+SX, camphor+SX,d-camphor+SX, arboxide+SX, dibutyl phthalate+SX, deet+SX, dimethylcarbate+SX, dimethyl phthalate+SX, dibutyl succinate+SX, dibutyladipate+SX, ethohexadiol+SX, hexamide+SX, icaridin+SX,methoquin-butyl+SX, methylneodecanamide+SX, 2-(octylthio)ethanol+SX,butoxypolypropylene glycol+SX, oxamate+SX, quwenzhi+SX, quyingding+SX,zengxiaon+SX, rebemide+SX, copper naphthenate+SX, and zincnaphthenate+SX.

Combination of the Present ingredient of the above Group (g) and thePresent compound Z

bis(tributyltin) oxide+SX, allicin+SX, bromoacetamide+SX,cloethocarb+SX, copper sulfate+SX, fentin+SX, ferric phosphate+SX,metaldehyde+SX, niclosamide+SX, pentachlorophenol+SX, sodiumpentachlorophenoxide+SX, tazimcarb+SX, tralopyril+SX, andtrifenmorph+SX.

Combination of the Present ingredient of the above Group (h) and thePresent compound Z:

(E)-2-hexenal+SX, (E)-2-octadecenal+SX, (E)-4-tridecen-1-yl acetate+SX,(E)-5-decen-1-yl acetate+SX, (E)-5-decen-1-ol+SX,(E)-3,3-dimethylcyclohexylideneacetaldehyde+SX, (E)-7-dodecen-1-ylacetate+SX, (E)-8-dodecen-1-yl acetate+SX, (E)-9-dodecen-1-ylacetate+SX, (E)-10-hexadecenal+SX, (E)-11-hexadecen-1-yl acetate+SX,(E)-11-tetradecen-1-yl acetate+SX, (E)-11-tetradecen-1-ol+SX,(E)-4-tridecen-1-yl acetate+SX, (E)-6-methylhept-2-en-4-ol+SX,(Z)-2-(3,3-dimethylcyclohexylidene)ethanol+SX, (Z)-4-decen-1-ylacetate+SX, (Z)-4-tridecen-1-yl acetate+SX, (Z)-5-decen-1-yl acetate+SX,(Z)-5-decen-1-ol+SX, (Z)-7-tetradecenal+SX, (Z)-7-dodecen 1-ylacetate+SX, (Z)-8-dodecen-1-yl acetate+SX, (Z)-9-dodecen-1-ylacetate+SX, (Z)-8-dodecen-1-ol+SX, (Z)-9-hexadecenal+SX,(Z)-10-hexadecen-1-yl acetate+SX, (Z)-11-hexadecen-1-ol+SX,(Z)-11-hexadecenal+SX, (Z)-11-hexadecen-1-yl acetate+SX,(Z)-11-octadecenal+SX, (Z)-13-octadecenal+SX,(Z)-hexadec-13-en-11-yn-1-yl acetate+SX, (Z)-13-octadecenal+SX,icos13-en-10-one+SX, (Z)-7-tetradecenal+SX, (Z)-tetradec-9-en-1-ol+SX,(Z)-9-tetradecen-1-yl acetate+SX, (Z)-11-tetradecen-1-yl acetate+SX,(Z)-13-icosen-10-one+SX, (Z,E)-7,11-hexadecadien-1-yl acetate+SX,(Z,E)-9,12-tetradecadien-1-yl acetate)+SX, (E,Z)-4,10-tetradecadien-1-ylacetate+SX, (E,E)-10-dodecadien-1-ol+SX, (E,E)-10,12-hexadecadienal+SX,(E,E)-9,11-tetradecadien-1-yl acetate+SX,(E,Z)-2,13-octadecadien-1-ol+SX, (E,Z)-3,13-octadecadien-1-ol+SX,(E,Z)-2,13-octadecadien-1-yl acetate+SX, (E,Z)-3,13-octadecadien-1-ylacetate+SX, (E,Z)-7,9-dodecadien-1-yl acetate+SX,(E,E)-7,8-dodecadien-1-yl acetate+SX, (Z,E)-9,12-tetradecadien-1-ylacetate+SX, (Z,E)-9,11-tetradecadien-1-yl acetate+SX,(Z,E)-7,11-hexadecadien-1-yl acetate+SX,(Z,Z)-3,13-octadecadien-1-ol+SX, (Z,Z)-4,7-decadien-1-yl acetate+SX,(Z,Z)-3,13-octadecadien-1-yl acetate+SX, (Z,Z)-7,11-hexadecadien-1-ylacetate+SX, (Z,Z,E)-7,11,13-hexadecatrienal+SX,(5R)-5-[(1Z)-1-decen-1-yl]dihydro-2(3H)-furanone+SX,(2R,5R)-ethyl-1,6-dioxaspiro[4,4]nonane+SX,(2R,5S)-ethyl-1,6-dioxaspiro[4,4]nonane+SX,(4R,8R)-4,8-dimethyldecanal+SX, (4R,8S)-4,8-dimethyldecanal+SX,2,4-dimethyl-5-ethyl-6,8-dioxabicyclo[3,2,1]octane+SX,(−)-4-methyl-3-heptanol+SX, 1,7-dioxaspiro[5,5]undecane+SX, 3-carene+SX,methylcyclohex-2-en-1-one+SX, 14-methyloctadec-1-ene+SX,4-methylnonan-5-ol+SX, 4-methylnonan-5-one+SX, 4-(3-oxobutyl)phenylacetate+SX, dodecyl acetate+SX, dodeca-8,10-dien-1-yl acetate+SX, ethyl(2E,4Z)-decadienoate+SX, ethyl 4-methyloctanoate+SX, methyl2,6,10-trimethyldodecanoate+SX, tetradecan-1-ol+SX,tetradec-11-en-1-ol+SX, tetradec-11-en-1-yl acetate+SX, tridec-4-en-1-ylacetate+SX, (3S,6R)-3-methyl-6-isopropenyl-9-decen-1-yl acetate+SX,(3S,6S)-3-methyl-6-isopropenyl-9-decen-1-yl acetate+SX,alpha-multistriatin+SX, alpha-pinine+SX, endo-brevicomin+SX,exo-brevicomin+SX, camphene+SX, codlelure+SX, codlemone+SX, cuelure+SX,disparlure+SX, dominicalure+SX, eugenol+SX, farnesol+SX, ferrolure+SX,frontalin+SX, gossyplure+SX, grandlure+SX, grandlure I+SX, grandlureII+SX, grandlure III+SX, grandlure IV+SX, hexalure+SX, ipsdienol+SX,ipsenol+SX, japonilure+SX, lineatin+SX, litlue+SX, looplure+SX,medlure+SX, megatomoic acid+SX, methyl eugenol+SX, muscalure+SX,nerolidol+SX, orfralure+SX, oryctalure+SX, ostramone+SX, rhyncolure+SX,siglure+SX, sordidin+SX, sulcatol+SX, trimedlure+SX, trimedlure A+SX,trimedlure B1+SX, trimedlure B2+SX, trimedlure C+SX, trunc-call+SX,(E)-verbenol+SX, (Z)-verbenol+SX, trans-verbenol+SX, and(S)-verbenone+SX.

The ratio of the Present compound Z to the Present ingredient includes,but not limited thereto, as a ration by weight (the Present compound Z:the Present ingredient) 1,000:1 to 1:1,000, 500:1 to 1:500, 100:1 to1:100, 50:1 to 1:50, 20:1 to 1:20, 10:1 to 1:10, 3:1 to 1:3, 1:1 to1:500, 1:1 to 1:100, 1:1 to 1:50, 1:1 to 1:20, or 1:1 to 1:10, abd theothers.

Examples of the pests on which the present compound Z or the presentcomposition has efficacies include harmful arthropods such as harmfulinsects and harmful mites, harmful nematodes, and harmful molluscs, andspecific examples of the harmful arthropods include the followings, butwhich are not limited thereto.

Hemiptera Pests:

Delphacidae (for example, Laodelphax striatellus, Nilaparvata lugens,Sogatella furcifera, Peregrinus maidis, Javesella pellucida,Perkinsiella saccharicida, or Tagosodes orizicolus);

Cicadellidae (for example, Nephotettix cincticeps, Nephotettixvirescens, Nephotettix nigropictus, Recilia dorsalis, Empoasca onukii,Empoasca fabae, Dalbulus maidis, or Cofana spectra);

Cercopidae (for example, Mahanarva posticata, or Makanarva fimbriolata);

Aphididae (for example, Aphis fabae, Aphis glycines, Aphis gossypii,Aphis pomi, Aphis spiraecola, Myzus persicae, Brachycaudus helichrysi,Brevicoryne brassicae, Rosy apple aphid (Dysaphis plantaginea), Lipaphiserysimi, Macrosiphum euphozbiae, Aulacorthum solani, Nasonoviaribisnigri, Rhopalosiphum padi, Rhopalosiphum maidis, Toxoptezacitricidus, Hyalopterus pruni, Melanaphis sacchari, Tetraneuranigriabdominalis, Ceratovacuna lanigera, or Eriosoma lanigerum);

Phylioxeridae (for example, Daktulosphaira vitifoliae, Pecan phylloxera(Phylloxera devastatrix), Pecan leaf Phylloxera (Phylloxera notabilis),or Southern pecan leaf Phylloxera (Phylloxera russellae));

Adelgidae (for example, Adelges tsugae, Adelgas piceae, or Aphrastatsiapectinatae);

Pentatomidae (for example, Scotinophara lurida, Malayan rice black bug(Scotinophara coarctate) Nezara antennata, Eysarcoris aeneus, Eysarcorislewisis, Eysarcaris ventralis, Eysarcoris annamita, Halyomorpha halys,Nezara viridula, Brown stink bug (Euschistus heros), Red banded stinkbug (Piezodorus guildinii), Oebalus pugnax, Dichelops melacanthus);

Cydnidae (for example, Burrower brown bug (Scaptocoris castanea));

Alydidae (for example, Rilotortus pedestris, Leptocorisa chinensis, orLeptocorisa acuta);

Coreidae (for example, Cletus punctiger, or Leptoglossus australis);

Lygaeidae (for example, Caverelius saccharivorus, Togo hemipterus, orBlissus leucopterus);

Miridae (for example, Trigonotylus caelestialium, Stenotusrubrovittatus, Stenodema calcarata, or Lygus lineolaris);

Aleyrodidae (for example, Trialeurodes vaporariorum, Bemisia tabaci,Dialeurodes citri, Aleuaocanthus spiniferus, Aleurocanthus camelliae, orPealius euryae);

Diaspididae (for example, Abgrallaspis cyanophylli, Aonidiella aurantii,Diaspidiotus perniciosus, Pseudaulacaspis pentagona, Unaspis yanonensis,or Unaspis citri);

Coccidae (for example, Ceroplastes rubens);

Margarodidae (for example, Icerya purchasi, or Icerya seychellarum);

Pseudococcidae (for example, Phenacoccus solani, Phenacoccus solenopsis,Planococcus kraunhiae, Planococcus comstocki, Planococcus citri,Pseudococcus calceolariae, Pseudococcus longispinus, or Brevennia rehi);

Psyllidae (for example, Diaphorina citri, Trioza erytreae, Cacopsyllapyrisuga, Cacopsylla chinensis, Bactericera cockerelli, or Pear psylla(Cacopsylla pyricole));

Tingidae (for example, Corythucha ciliata, Corythucha marmorata,Stephanitis nashi, or Stephanitis pyrioides);

Cimicidae (for example, Cimex lectulerius);

Cicadidae (for example, Giant Cicada (Quesada gigas)); and

Triatoma spp. (for example, Triatoma infestans).

Lepidoptera

Crambidae (for example, Chilo suppressalis, Darkheaded stem borer (Chilopolychrysus), White stem borer (Scirpophaga innotata), Scirpophagaincertulas, Rupela albina, Cnaphalocrocis medinalis, Marasmia patnalis,Marasmia exigua, Notarcha derogata, Ostrinia furnacalis, European cornborer (Ostrinia nubilalis), Hellula undalis, Herpetogramma luctuosale,Pediasia teterrellus, Nymphua depunctalis, or Sugarcane borer (Diatraeasaccharalis));

Pyralidae (for example, Elasmpalpus lignosellus or Plodiainterpunctella);

Noctuidae (for example, Spodoptera litura, Spodoptera exigua, Mythimnaseparata, Memestra brassicae, Sesamia inferens, Spodoptera mauritia,Narang aenescens, Spodoptera frugiperda, Spodoptera exempta, Agrotisipsilon, Autographa nigrisigna, Plusia festucae, Soybean looper(Chrysodeixis includens), Trichoplusia spp., Heliothis spp. (forexample, Heliothis virescens), Helicoverpa armigera, Helicoverpa spp.(for example, Helicoverpa zea), Velvetbean caterpillar (Antiarsiagemmatalis), Cotton leafworm (Alabama argillacea), or Hop vine borer(Hydraecia immanis)),

Pieridae (for example, Pieris rapae);

Tortricidae (for example, Grapholita molesta, Grapholita dimorphs,Leguminivora glycinivorella, Matsumuraeses azukivora, Adoxophyes oranafasciata, Adoxophyes honmai, Homona magnanima, Archips fuscocupreanus,Cydia pomonella, Tetramoera schistaceana, Bean Shoot Borer (Epinotiaaporema), or Citrus fruit borer (Ecdytolopha aurantiana));

Gracillariidae (for example, Caloptilia theivora, or Phyllonorycterringoniella);

Carposinidae (for example, Carposina sasakii);

Lyonetiidae (for example, Coffee Leaf miner (Leucoptera coffeela),Lyonetia clerkella, or Lyonetia prunifoliella);

Lymantriidae (for example, Lymantria spp. (for example, Lymantriadispar), or Euproctis spp. (for example, Euproctis pseudoconspersa);

Pluteliidae (for example, Plutella xylostella);

Gelechiidae (for example, Anarsia lineatella, Helcystogrammatriannulellun, Pectinophora gossypiella, Phthorimaea operculella, orTuta absolut);

Arctiidae (for example, Hyphantria cunea);

Castniidae (for example, Giant Sugarcane borer (Telchin licus));

Cossidae (for example, Cosus insularis);

Geometridae (for example, Ascotis selenaria);

Limacodidae (for example, Parasa lepida);

Stathmopodidae (for example, Stathmopoda masinissa);

Sphingidae (for example, Acherontic lachesis);

Sesiidae (for example, Nokona feralis);

Hesperiidae (for example, Parnara guttate); and

Tinedae (for example, Tinea translucens or Tineola bisselliella).

Thysanoptera

Thripidae (for example, Frankliniella occidentalis, Thrips palmi,Scirtothrips dorsalis, Thrips tabaci, Frankliniella intonsa,Stenchaetothrips biformis, or Echinothrips americanus); and

Phlaeothripidae (for example, Haplothrips aculeatus).

Diptera

Anthomyiidae (for example, Delia platura or Delia antigua);

Ulidiidae (for example, Tetanops myopaeformis);

Agromyzidae (for example, Agromyza oryzae, Liriomyza sativae, Liriomyzatrifolii, or Chromatomyi horticola);

Chloropidae (for example, Chlorops oryzae);

Tephritidae (for example, Bactrocera cucurbitae, Bactrocera dorsalis,Bactrocera latifrons, Bactrocera oleae, Bactrocera tryoni, or Ceratitiscapitata);

Ephydridae (for example, Hydrellia griseala, Hydrellia philippina, orHydrellia sasakii);

Drosophilidae (for example, Drosophila suzukii);

Phoridae (for example, Megaselia spiracularis);

Psychodidae (for example, Clogmia albipunctata);

Salaridae (for example, Bradysia difformis);

Cecidomyiidae (for example, Mayetiola destructor, or Orseolia oryzae);

Diopsidae (for example, Diopsis macrophthalma);

Tipulidae (for example, Tipula aino, Common cranefly (Tipula oleracea),or European cranefly (Tipula paludosa)).

Culicidae (for example, Culex pipiens pallens, Aedes aegypti, Aedesalbopicutus, Anopheles hyracanus sinesis, Culex quinquefasciatus, Culexpipiens molestus Forskal, or Culex quinquefasciatus);

Simulidae (for example, Prosimulium yezoensis, or Simulium ornatum);

Tabanidae (for example, Tabanus trigonus);

Muscidae (for example, Musca domestica, Muscina stabulans, Stomoxyscalcitrans, or Haematobia irritans);

Calliphoridae;

Sarcophagidae;

Chironomidae (for example, Chironomus plumosus, Chironomus yoshimatsui,or Glyptotendipes tokunagai); and

Fannidae.

Coleoptera

Chrysomelidae (for example, Diabrotica virgifera virgifera, Diabroticaundecimpuictata howardi, Diabrotica barberi, Diabrotica virgifera zeae,Diabrotica balteata, Cucurbit Beetle (Diabrotica speciosa), Cerotomatrifurcate, Oulema melanopus, Aulacophora femoralis, Phyllotretastriolata, Cabbage flea beetle (Phyllotreta cruciferae), Western blackflea beetle (Phyllotreta pusilla), Cabbage stem flea beetle (Psylliodeschrysocephala), Leptinotarsa deceralineata, Qulema oryzae, Colaspisbrunnea, Chaetocnema pulicaria, Chaetocnena confinis, Epitrix cucumeris,Dicladispa armigera, Grape colaspis (Colaspis brunnea), southern cornleaf beetle (Myochrous denticollis), Laccoptera quadrimacu, or Epitrixhirtipennis);

Carabidae (for example, Seedcorn beetle (Stenolophus lecontei), orSlender seedcorn beetle (Clivina impressifros));

Scarabaeidae (for example, Anomala cuprea, Anomala rufocuprea, Anomalaalbopilosa, Popillia japonica, Heptophylla picea, European Chafer(Rhizotrogus majalis), Tomarus gibbosus, Holotrichia spp., Phyllophagaspp. (for example, Phyllophaga crinita), or Diloboderus spp. (forexample, Diloboderus abderus);

Curculionidae (for example, Araecerus coffeae, Cylas formicarius,Euscepes post fasciatus, Hypera postica, Sitophilus zeamais,Echinocmemus squameus, Lissorhoptrus oryzophilus, Rhabdosceluslineatocollis, Anthonomus grandis, Sphenophorus latus, Southern CornBilibug (Sphenophorus callosus), Soybean stalk weevil (Sternechussubsignatus), Sgarcane wiivil (Sphenophorus levis), Scepticus griseus,Scepticus uniformis, Zabrotes subfasciatus, Tomicus piniperda, CoffeeBerry Borer (Hypothenemus hampei), Aracanthus spp. (for example,Aracanthus mourei), or Curculionidae (for example, cottox root borer(Eutinobothrus brasiliensis)

Tenebrionidae (for example, Tribolium castaneum, or Tribolium confusum);

Coccinellidae (for example, Epilachna vigintioctopunctata);

Bostrychidae (for example, Lyctus brunneus);

Ptinidae;

Cerambycidae (for example, Anoplophora malasiaca, or Migdolus fryanus);

Elateridae (for example, Melanotus okinawensis, Agriotes fuscicollis,Melanotus legatus, Anchastus spp., Conoderus spp., Ctenicera spp.,Limonius spp., or Aeolus spp.);

Staphylinidae (for example, Paederus fuscipes);

Dermestidae (for example, Anthrenus verbasci, or Dermestes maculate);

Anobidae (for example, Lasioderma serricorne, or Stegobium paniceum).

Orthoptera

Acrididae (for example, Locusta migratoria, Dociostaurus marcccanus,Chortoicetes terminifera, Nomadacris septemfasciata, Brown Locust(Locustana pardalina), Tree Locust (Anacridium melanorhodon), ItalianLocust (Calliptamus italicus), Differential grasshopper (Melanoplusdifferentialis), Two striped grasshopper (Melanoplus bivittatus),Migratory grasshopper (Melanoplus sanguinipes), Red-Legged grasshopper(Melanoplus femurrubrum), Clearwinged grasshopper (Camnula pellucida),Schistocerca gregaria, Yellow-winged locust (Gastrimargus musicus),Spur-throated locust (Austracris guttulosa), Oxya yezoensis, Qxyajaponica, or Patanga succincta);

Grvilotalpidae (for example, Gryllotalpa orientalis);

Gryllidae (for example, Acheta domestica, or Teleogryllus emma); and

Tettigoniidae (for example, Mormon cricket (Anabrus simplex)).

Hymenoptera

Tenthredinidae (for example, Athalia rosae, or Athalia japonica);

Formicidae (for example, Solenopsis spp. (for example, Solenopsisinvicta, or Solenop geminata), Atta spp. (for example, Brownleaf-cutting ant (Atta capiquara)), Acromyrmex spp., Camponotus spp.(for example, Paraponera clavata, Ochetellus glaber, Monomoriumphareonis, Linepithema humile, Formica fusca japonica, Pristomyrmexpunctutus), Pheidole node, Pheidole megacephala, Camponotus japonicus,or Camponotus obscuripes), Pogonomyrmex spp. (for example, Pogonomyrmexoccidentalis), Wasmania spp. (for example, Wasmania auropunctata), orAnopiolepis gracilipes)

Vespidae (for example, Vespa mandarinia japonica, Vespa simillima, Vespaanalis Fabriciusi, Vespa velutina, Polistes jokahamae);

Siricidae (for example, Urooerus gigas); and Bethylidae.

Blattodea

Blattellidae (for example, Blattella germanica);

Blattidae (for example, Periplaneta fuliginosa, Periplaneta americana,Periplaneta brunnea, or Blatta orientalis);

Termitidae (for example, Reticulitermes speratus, Coptotermesformosanus, Incisitermes minor, Cryptotermes domesticus, Odontotermesformosanus, Neotermes koshunensis, Glyptotermes satsumensis,Glyptotermes nakajimai, Glyptotermes fuscus, Hodotermopsis sjostedti,Coptotermes guanqzhouensis, Reticulitermes amamianus, Reticulitermesmiyatakei, Reticulitermes kanmonensis, Nasutitermes takasagoensis,Pericapritermes nitobei, Sinocapritermes mushae, or Cornitermescumulans).

Siphonaptera

Ctenocephalidae felis, Ctenocephalides canis, Pulex irritans, Xenopsyllacheopis, Tunga penetrans, Echidnophaga gallinacea, and Nosopsyllusfasciatus.

Anoplura

Haematopinus suis, Haematopinus eurysternus, Dalmalinia ovis,Linognathus seypsus, Pediculus humanis, Pediculuc humanus corporis,Pediculus humanus humanus, and Phthirus pubis.

Mallophagida

Menoponidae such as Bovicola spp. (for example, Dalmalinia bovis, orDalmalinia avis), Trichodectes spp. (for example, Trichodectes canis),Felocola spp. (for example, Felicola subrostrata), Lipeurus spp, (forexample, Lipeurus caponis), Trimenopon spp., and Menopon spp.

Acari

Tetranychidae (for example, Tetranychus urticae, Tetranychus kanzawai,Tetranychus evansi, Panonychus citri, Panonychus ulmi, or Oligonychusspp.);

Eriophyidae (for example, Aculops pelekassi, Phyllocoptruta citri,Aculops lycopersici, Calacarus carinatus, Acaphylla theavagrans,Eriophyes chibaensi Aculus schlechtendali, Aceria diospyri, Aceriatosicheila, or Shevtchenkella sp.);

Tarsonemidae (for example, Polyphagot sonemus latus);

Tenuipalpidae (for example, Brevipalpus phoenicis);

Tuckerellidae;

Ixodidae (for example, Haemaphysalis longicornis, Haemaphysalis flava,Dermacentor taiwanensis, Dermacentor variabilis, Dermacentor andersoni,Ixodes ovatus, Ixodes persulcatus, Ixodes ricinus, Ixodes scapularis,Amblyomma americanum, Ambryomma maculatum, Boophilus microplus,Boophilus annulatus, or Rhipicephalus sanguineus);

Acaridae (for example, Tyrophagus putrescentiae, or Tyrophagussimilius);

Pyroglyphidae (for example, Dermatophagoides farinae, orDermatophagoides pteronyssinus);

Cheyletidae (for example, Cheyletus eruditus, Cheyletus malaccensis,Cheyletus moorei, or Cheyletiella yasguri);

Sarcoptidae (for example, Otodectes cynotis, or Sarcoptes scabiei);

Demodicidae (for example, Demodex canis);

Listrophoridae;

Haplochthoniidae;

Macronyssidae (for example, Ornithonyssus bacoti, or Ornithonyssussylviarum);

Dermanyssidae (for example, Dermanyssus gallinae); and

Trombiculidae (for example, Leptotrombidium akamushi).

Araneae

Eutichuridae (for example, Cheiracanthium japonicum); and Theridiidae(for example, Latrodectus hasseltii).

Polydesmida

Paradoxosomatidae (for example, Oxidus gracilis and Nedyopus tambanus);

Isopoda

Armadillidiidae (for example, Armadillidium vulgare).

Chilopoda

Scutigeridae (for example, Thereuonema hilgendorfi); Scolopendridae (forexample, Scolopendra subspinipes) and Ethopolidae (for example,Bohropolys rugosus).

Gastropoda

Limacidae (for example, Limax marginatus, or Limax flavus); Philomycidae(for example, Meghimatium bilineatum); Ampullariidae (for example,Pomacea canaliculata); and Lymnaeidae (for example, Austropepleaollula).

Nematoda

Aphelenchoididae (for example, Aphelenchoides besseyi); Pratylenchidae(for example, Pratylenchus coffeae, Pratylenchus brachyurus,Pratylenchus neglectus, or Radopholus similis); Heteroderidae (forexample, Meloidogyne javanica, Meloidogyne incognita, Meloidogyne hapla,Heterodera glycines, Globodera rostochiensis, or Globodera pallida):Hoplolaimidae (for example, Rotydenchulus reniformis); Anguinidae (forexample, Nothotylenchus auris, or Ditydenchus dipsaci); Tylenchulidae(for example, Tylenchulus semipenetrans); Longidoridae (for example,Xiphinema index); Trichodoridae; and Parasitaphelenchidae (for example,Bursaphelenehus xylophilus).

The harmful insects and harmful mites to be targeted may be insects andmites whose sensitivity to the insecticides and miticides. However, whenthe sensitivity to chemicals is largely reduced or the resistanceagainst chemicals is largely developed, it is desirable to use theposition of the present invention comprising any insecticides andmiticides other than the insecticides and the miticides to be targeted.

The present compound Z or the present composition may be used to protectplants from the plant diseases csused by insect-mediated viruses orinsect-mediated bacteria.

Examples of the insect-mediated viruses are included the followings.

Rice tungro spherical virus, Rice tungro bacilliform virus, Rice grassystunt virus, Rice ragged stunt virus, Rice stripe virus, Rice blackstreaked dwarf virus, Southern rice black-streaked dwarf virus, Ricegall dwarf virus, Rice hoja blanca virus, Rice yellow stunt virus, Riceyellow mottle virus, Rice dwarf virus, Northern cereal mosaic virus,Barley yellow dwarf virus, Barley mild mosaic virus, Barley yellow dwarfvirus-PAV, Cereal yellow dwarf virus-RPS, Wheat yellow leaf virus, Oatsterile dwarf virus, Wheat streak mosaic virus, Maize dwarf mosaicvirus, Maize stripe virus, Maize chlorotic mottle virus, Maize chloroticdwarf virus, Maize rayado fino virus, Sugarcane mosaic virus, Fijidisease virus, Sugarcane yellow leaf virus, Soybean, mild mosaic virus,Cycas necrotic stunt, Soybean dwarf virus, Milk vetch dwarf virus,Soybean mosaic virus, Alfalfa mosaic virus, Bean yellow mosaic virus,Bean common mosaic virus, Southern bean mosaic virus, Peanut stuntvirus, Broad bean wilt virus 1, Broad bean wilt virus 2, Broad beannecrosis virus, Broad bean yellow vein virus, Clover yellow vein virus,Peanut mottle virus, Tobacco streak virus, Bean pod mottle virus, Cowpeachlorotic mottle virus, Mung bean yellow mosaic virus, Soybean crinkleleaf virus, Tomato chlorosis virus, Tomato spotted wilt virus, Tomatoyellow leaf curl virus, Tomato aspermy virus, Tomato infectiouschlorosis virus, Potato leafroll virus, Potato virus Y, Melon yellowspot virus, Melon necrotic spot virus, Watermelon mosaic virus, Cucumbermosaic virus, Zucchini yellow mosaic virus, Turnip mosaic virus, Turnipyellow mosaic virus, Cauliflower mosaic virus, Lettuce mosaic virus,Celery mosaic virus, Beet mosaic virus, Cucurbit chlorotic yellowsvirus, Capsicum chlorosis virus, Beet pseudo yellows virus, Leak yellowstripe virus, Onion yellow dwarf virus, Sweet potato feathery mottlevirus, Sweet potato shukuyo mosaic virus, Strawberry mottle virus,Strawberry mild yellow edge virus, Strawberry pseudo mild yellow edgevirus, Strawberry crinkle virus, Strawberry vein banding virus, plum poxvirus, Chrysanthemum stem necrosis virus, Impatiens necrotic spot virus,Iris yellow spot virus, Lily mottle cirus, Lilly symptomless virus,Tulip mosaic virus, and the like.

Examples of the insect-mediated bacetria are included the followings.

Candidatus Phytoplasma oryzae, Candidatus Phytoplasma asteris, Maizebushy stunt phytoplasma, Candidatus Liberbacter asiaticus, CandidatusLiberbacter africanus, Candidatus Liberbacter amer canus, and the like.

When the present ingredient is a fungicide active ingredient, thecomposition of the present invention can be used to control plantdiseases. Examples of the plant disease include the following. Here thedescriptions in a parenthesis indicates an academic name ofphytopathogenic microorganism that causes the disease.

Rice diseases: blast (Magnaporthe grisea), brown spot (Cochliobolusmiyabeanus), sheath blight (Rhizoctonia solani), bakanae disease(Gibberella fujikuroi), and downy mildew (Sclerophthora macrospora);

Wheat diseases: powdery mildew (Erysiphe graminis), fusarium blight(Fusarium graminearum, F. avenaceum, F. culmorum, Microdochium nivale),stem rust (Puccinia striiforruis, P. graminis, P. recondita), snow mould(Microdochium nivale, M. majus), typhulasnow snow blight (Typhula sp.),loose smut (Ustilago tritici), stinking smut (Tilletia caries, T.controversa), eyespot (Pseudocercosporella herpotrichoides), septorialeaf blotch (Septoria tritici), glume blotch (Stagonospora nodorum), tanspot (Pyrenophora tritici-repentis), Rhizoctonia seeding blight(Rhizoctonia solani), and take-all disease (Gaeumannomyces graminis);

Barley diseases: owdery mildew (Erysiphe graminis), Fusarium blight(Fusarium graminearum, F. avenaceum, F. culmorum, Microdochium nivale),stem rust (Puccinia striiformis, P. graminis, P. hordei), loose smut(Ustilago nuda), scald (Rhynchosporium secalis), scald (Rhynchosporiumsecalis), net blotch (Pyrenophora teres), spot blotch (Cochliobolussativus), stripe (Pyrenophora graminea), Ramularia disease (Ramulariacollo-cygni), stripe rust. (Puccinia striiformis), stun rust (Pucciniagraminis), dwarf leaf rust (Puccinia hordei), loose smut (Ustilagonuda), scald (Rhynchosporium secalis), net blotch (Pyrenophora teres),spot blotch (Cochliobolus sativus), stripe (Pyrenophora graminea),Ramularia disease (Ramularia colllo-cygni), and Rrhizoctonia seedingblight (Rhizoctonia solani);

Corn diseases: rust (Puccinia sorghi), southern rust (Pucciniapolysora), northern leaf blight (Setosphaeria turcica), tropical rust(Physopella zeae), southern leaf blight (Cochliobolus heterostrophus),anthracnose (Colletotrichum graminicola), gray leaf spot (Cercosporazeae-maydis), eyespot (Kabatiella zeae), phaeosphaeria leaf spot(Phaeosphaeria maydis), diplodia rot (Stenocarpella maydis,Stenocarpella macrospora), stalk rot (Fusarlum graminearum, Fusariumverticilioides, Colletotrichum graminicola), smut (Ustilgo maydis);

Cotton diseases: anthracnose (Colletotrichum gossypii), grey mildew(Ramularia areola), alternaria leaf spot (Alternaria macrospore, A.gossypii), and black root rot (Thielaviopsis brasicola);

Coffee diseases: rust (Hemileia vastatrix), and leaf spot (Cercosporacoffeicola);

Rape seed diseases: Sclerotinia rot (Sclerotinia sclerotiorum), grayleaf spot (Alternaria brassicae), and root rot (Phoma lingam);

Sugar cane diseases: rust (Puccinia melanocephela, Puccinia kuehnii),and smut (Ustilago scitaminea);

Sunflower diseases; rust (Puccinia heliathi), and downy mildew(Plasmopara halstedii);

Citrus diseases: melanose (Diaporthe citri), scab (Elsinoe fawcetti),mold (Penicillium digitatum, Penicillium italicum), and Phytophthora rot(Phytophthora parasitica, Phytophthora citrophthora);

Apple diseases: blossom blight (Monilinia mali), valsa canker (Valsaceratosperma), powdery mildew (Podosphaera leucotricha), alternaria leafspot (Alternaria alternata apple pathotype), scab (Venturia inaequalis),bitter rot (Glomerella cingulata), blotch (Diplocarpon mali), ring rut(Botryosphaeria berengeriana), crown rot (Phytophtora cactorum);

Pear diseases: scab (Venturia nashicola, V. pirina), black spot(Alternaria alternata Japanese pear pathotype), rust (Gymnosporangiumharaeanum);

Peach diseases: brown rot (Monilinia fructicola), scab (Cladosporiumcarpophilum), Phomopsis rot (Phomopsis sp.), and leaf curl (Taphririadeformans);

Grapes diseases: anthracnose (Elsinoe ampelina), ripe rot (Glomerellacingulata), powdery mildew (Uncinula necator), rust (Phakopsoraampelopsidis), black rot (Guignardia bidwellii), and downy mildew(Plasmopara viticola);

Japanese persimmon diseases: anthracnose (Gloeosporium kaki,Colletotrichum acutatum), and leaf spot (Cercospora kaki, Mycosphaerellanawae);

Diseases of gourd family: anthracnose (Colletotrichum lagenarium),powdery mildew (Sphaerotheca fuliginea), gummy stem blight (Didymellabryoniae), Corynespora leaf spot (Corynespora cassiicola), Fusarium wilt(Fusarium oxysporum), downy mildew (Pseudoperonospora cubensis),Phytophthora rot (Phytophthora sp.), and damping-off (Pythium sp.);

Tomato diseases: early blight (Alternaria solani), leaf mold(Cladosporium fulvum), CercosPora leaf mold (Pseudocercospora fuligena),late blight (Phytophthora infestans), and powdery mildew (Leveillulataurica);

Eggplant diseases: brown spot (Phomopsis vexans), and powdery mildew(Erysiphe cichoracearum);

Cruciferous vegetables diseases: Alternaria leaf spot (Alternariajaponica), white spot (Cercosporelia brassicae), clubroot(Plasmodiophora brassicae), downy mildew (Peronospora parasitica);

Welsh onion disease: rust (Puccinia allii);

Soybean diseases: purple stain (Cercospora kikuchii), sphaceloma scab(Elsinoe glycines), pod and stem blight (Diaporthe phaseolorum var.sojae), rust (Phakopsora pachyrhizi), target spot (Corynesporacassiicola), anthracnose (Colletotrichum glycines, C. truncatum),Rhizoctonia rot (Rhizoctonia solani), Septoria brown spot (Septoriaglycines), Cercospora leaf spot (Cercospora sojina), stem rot(Sclerotinia sclerotiorum), powdery mildew (Microsphaera diffusa),Phytophthora stem and root rot (Phytophthora sojae), downy mildew(Peronospora manshurica), sudden death syndrome (Fusarium virguliforme),

Kidney bean diseases: stem rot (Sclerotinia sclerotiorum), rust(Uromyces appendiculatus), angular leaf spot (Phaeoisariopsis griseola),and anthracnose (Colletotrichum lindemuthianum);

Peanut diseases: leaf spot (Cercospora personata), brown leaf spot(Cercospora arachidicola), and southern blight (Sclerotium rolfsii);

Garden pea disease: powdery mildew (Erysaphe pisi);

Potato diseases: early blight (Alternaria solani), late blight(Phytophthora infestans), Pink rot (Phytophthora erythroseptica),powdery scab (Spongospora subterraneaf. sp. subterranea), andVerticillium wilt (Verticillium alto-atzum, Verticillium dahliae,Verticillium nigrescens;

Strawberry disease: powdery mildew (Sphaerotheca humuli);

Tea diseases: net blister blight (Exobasidium reticulatum), white scab(Elsinoe leucospila), gray blight (Pestalotiopsis sp.), and anthracnose(Colletotrichum theae-sinensis); Tobacco diseases: brown spot(Alternaria longipes), anthracnose (Collectotrichum tabacum), blue mold(Peronospora tabacina), and black shank (Phytophthora nicotianae);

Sugar beet diseases: Cercospora leaf spot (Cercospora beticola), leafblight (Thanatephorus cucumeris), root rot (Thanatephorus cucumeris),and Aphanomyces root rot (Aphanomyces cochlioides), and rust (Uromycesbetae);

Rose diseases: black spot (Diplocarpon rosae), and powdery mildew(Sphaerotheca pannosa);

Chrysanthemum diseases: leaf blight (Septoria chrysanthemi-indici), andwhite rust (Puccinia horiana);

Onion diseases: Botrytis leaf blight (Botrytis cinerea, B. byssoidea, B.squamosa), gray-mold neck rot (Botrytis allii), and small sclerotialneck rot (Botrytis squamosa);

Various crops diseases: Botrytis rot (Botrytis cinerea), and Sclerotiniarot (Sclerotinia sclerotiorum);

Japanese radish disease: Alternaria leaf spot (Alternaria brassicicola);

Turfgrass diseases: dollar spot (Sclerotinia homoeocarpa), and brownpate and large patch (Rhizoctonia solani); as well as

Banana disease: Sigatoka disease (Mycosphaerella fijiensis,Myrosphaerella musicola).

Seed diseases or diseases in the early stages of the growth of variousplants caused by Aspergillus spp., Penicillium spp, Fusarium spp.,Gibberella spp., Tricoderma spp., Thielaviopsis spp., Rhizopus spp.,Mucor spp., Corticium spp., Phoma spp., Rhizoctonia spp. or Diplodiaspp.; and the like;

Viral diseases: viral diseases of several crops transmitted by Polymixaspp. or Olpidium spp.

Bacterial seedling blight of rice (Burkholderia plantarii), bacterialspot cucumber (Pseudomonas syringae pv. Lachrymans), bacterial wilt ofeggplant (Ralstonia solanacearum), canker of citrus (Xanthomonas citri),and bacterial soft rot of Chinese cabbage (Erwinia carotovora).

The harmful arthropods, harmful nematodes and phytopathogenic fungus maybe harmful arthropods, harmful nematodes or phytopathogenic fungus whosethe sensitivity to any of the present ingredient is lowered or whose theresistance against the present ingredient is developed.

The composition for controlling harmful arthropods of the presentinvention comprises the compound Z of the present invention or thecomposition of the present invention and an inert carrier. Thecomposition for controlling harmful arthropods of the present inventionis usually prepared by mixing the compound Z of the present invention orthe composition of the present invention with an inert carrier such assolid carrier, liquid carrier or gaseous carrier, and if necessary,adding surfactants and the other auxiliary agents for formulation, toformulate into emulsifiable concentrates, oil solutions, dustformulations, granules, wettable powders, flowables, microcapsules,aerosols, smoking agents, poison baits, resin formulations, shampooformulations, paste-like formulations, foams, carbon dioxideformulations, and tablets and the others. Such formulations may beprocessed into mosquito repellent coils, electric mosquito repellentmats, liquid mosquito formulations, smoking agents, fumigants, sheetformulations, spot-on formulations or formulations for oral treatment.Also, the composition for controlling harmful arthropods of the presentinvention comprises usually 0.0001 to 95% by weight of the compound Z ofthe present invention or the composition of the present invention.

Examples of the solid carrier to be used in the formulation include finepowders or granules of clays (for example, kaolin clay, diatomaceousearth, bentonite, Fubasami clay, or acid white clay), dry silica, wetsilica talcs, ceramics, other inorganic minerals (for example, sericite,quartz, sulfur, active carbon, or calcium carbonate) or chemicalfertilizers (for example, ammonium sulfate, ammonium phosphate, ammoniumnitrate, urea, or ammonium chloride) and the others; as well assynthetic resins (for example, polyester resins such as polypropylene,polyacrylonitrile, polymethyl methacrylate or polyethyleneterephthalate; nylon resins (for example, nylon-6, nylon-11, ornylon-66); polyamide resins; polyvinyl chloride, polyvinylidenechloride, vinyl chlor propylene copolymers, and the others).

Examples of the liquid carriers include water; alcohols (for example,methanol, ethanol, isopropyl alcohol, butanol, hexanol, benzyl alcohol,ethylene glycol, propylene glycol, or phenoxy ethanol); ketones (forexample, acetone, methyl ethyl ketone, or cyclohexanone); aromatichydrocarbons (for example, toluene, xylene, ethyl benzene, dodecylbenzene, phenyl xylyl ethane, or methylnaphthalere); aliphatichydrocarbons (for example, hexane, cyclohexane, kerosene, or light oil);esters (for example, ethyl acetate, butyl acetate, isopropyl myristate,ethyl oleate, diisopropyl adipate, diisobutyl adipate, or propyleneglycol monomethyl ether acetate); nitriles (for example, acetonitrile,or isobutyronitrile); ethers (for example, diisopropyl ether,1,4-dioxane, 1,2-dimethoxyethane, diethyleneglycol dimethyl ether,diethylene glycol monomethyl ether, propylene glycol monomethyl ether,dipropylene glycol monomethyl ether, or 3-methyoxy-3-methyl-1-butanol);amides (for example, DMF, or N,N-dimethylacetamide); sulfoxides (forexample, dimethyl sulfoxide); propylene carbonate; and vegetable oils(for example, soybean oil or cottonseedoil).

Examples of gaseous carrier include fluorocarbon, butane gas, liquefiedpetroleum was (LPG), dimethyl ether, and carbon dioxide gas.

Examples of the surfactants include nonionic surfactants such aspolyoxyethylenated alkyl ethers, polyoxyethylenated alkyl aryl ethers,and polyethylene glycol fatty acid esters; and anionic surfactants suchas alkyl sulfonates, alkylbenzene sulfonates and alkyl sulfates.

Examples of the other auxiliary agents for formulation include a binder,a dispersant, a colorant and a stabilizer. Specific examples includecasein, gelatin, polysaccharides (for example, starch, gum arabic,cellulose derivatives and alginic acid), lignin derivatives, bentonite,water-soluble synthetic polymers (for example, polyvinyl alcohol,polyvinyl pyrrolidone and polyacrylic acids), acidic isopropylphosphate, 2,6-di-tert-butyl-4-methylphenol, and a mixture of2-tert-butyl-4-methoxyphenol and 3-tert-butyl-4-methoxyphenol.

Examples of base material of the resin formulation include polyvinylchloride polymers, polyurethane and the others, and a plasticizer suchas phthalate esters (for example, dimethyl phthalate, dioctylphthalate), adipic acid esters and stearic acid may be added to thesebase materials, if necessary. The resin formulation can be prepared bymixing the compound of the present invention with the above-mentionedbase material, kneading the mixture, followed by molding it by injectionmolding, extrusion molding or pressure molding and the like. Theresultant resin formulation can be subjected to further molding orcutting procedure and the like, if necessary, to be processed intoshapes such as a plate, film, tape, net or string shape. These resinformulations can be processed into animal collars, animal ear tags,sheet products, trap strings, gardening supports and other products.

Examples of a base material for the poison baits include baitingredients such as grain powder, vegetable oil, saccharide andcrystalline cellulose, and if necessary, with addition of antioxidantssuch as dibutylhydroxytoluene and nordihydroguaiaretic acid,preservatives such as dehydroacetic acid, accidental ingestioninhibitors for children and pets such as a chili powder, insectattraction fragrances such as cheese flavor, onion flavor and peanutoil.

The method for controlling harmful arthropods of the present inventionis carried out by applying an effective amount of the compound Z of thepresent invention or the composition of the present invention to aharmful arthropod directly and/or a habitat thereof (for example, plantbodies, soil, an interior of a house, animal bodies). Also, the methodfor controlling harmful arthropods of the present invention may beapplied to seeds. In the method for controlling harmful arthropods ofthe present invention, the Present compound is usually used in the formof a harmful arthropod controlling composition.

When a composition for controlling harmful arthropods of the presentinvention is used for controlling harmful arthropods in an agriculturalfield, the application dose as an amount sf the compound Z of thepresent invention is usually within a range from 1 to 10,000 g per10,000 m². In the case of being applied to seeds, the application doseas an amount of the compound of the present invention is usually withina range of 0.001 to 100 g per 1 Kg seeds. When the composition forcontrolling harmful arthropods of the present invention is formulatedinto emulsifiable concentrate, wettable powder, or flowable formulation,the composition of the present invention is usually applied by dilutingit with water in such a way that a concentration of the concentration ofthe active ingredient is within a range from 0.01 to 10,000 ppm. Thegranular formulation, or the dust formulation etc., is usually appliedas itself without diluting it.

These formulations or an aqueous dilution thereof may be spargeddirectly to harmful arthropods or plants (such as crops) to be protectedfrom harmful arthropods, and also may be applied to the soil of cropland in order to control harmful arthropods which live there.

Also, the resin preparation which is processed into a sheet or a stringmay be applied by winding a plant with a sheet or a string of the resinpreparation, putting a string of the resin preparation around a crop sothat the plant is surrounded by the string, or laying a sheet of theresin preparation on the soil surface near the root of a plant.

When the composition for controlling harmful arthropods of the presentinvention is used to control harmful arthropods that live inside ahouse, the application dose as an amount of the Present compound Z isusually within a range from 0.01 to 1,000 mg per 1 m² of an area to betreated, in the case of using it on a planar area. In the case of usingit spatially, the application dose as an amount of the Present compoundZ is usually within a range from 0.01 to 500 mg per 1 m³ of the space tobe treated. When the composition for controlling harmful arthropods ofthe present invention is formulated into emulsifiable concentrates,wettable powders, flowables or the others, such formulations are usuallyapplied after diluting it with water in such a way that a concentrationof the active ingredient is within a range from 0.1 to 10,000 ppm, andthen sparging it. In the case of being formulated into oil solutions,aerosols, smoking agents, poison baits and the others, such formulationsare used as itself without diluting it.

When the composition for controlling harmful arthropods of the presentinvention is used for controlling external parasites of livestock suchas cows, horses, pigs, sheep, goats and chickens and small animals suchas dogs, cats, rats and mice, the agent of the present invention may beapplied to the animals by a known method in the veterinary field.Specifically, when systemic control is intended, the agent of thepresent invention is administered to the animals as a tablet, a mixturewith feed or a suppository, or by injection (including intramuscular,subcutaneous, intravenous and intraperitoneal injections). On the otherhand, when non-systemic control is intended, the agent of the presentinvention is applied to the animals by means of spraying of the oilsolution or aqueous solution, pour-on or spot-on treatment, or washingof the animal with a shampoo formulation, or by putting a collar or tagmade of the resin formulations to the animal. In the case of beingadministered to an animal body, the dose of rhe Present compound usuallywithin a range from 0.1 to 1,000 mg per 1 kg of an animal body weight.

Also, the Present compound Z or the Present composition may be used asan agent for controlling harmful arthropods in agricultural lands suchas paddy fields, fields, turfs, and orchards. The Present compound Z orthe Present composition may be controlled the harmful arthropods wherelives in agricultural lands where the following plants etc., are grown.

Crops:

corn, rice, wheat, barley, rye, oat, sorghum, cotton, soybean, peanut,buckwheat, beet, rapeseed, sunflower, sugar cane, tobacco, and theothers;

Vegetables:

solanaceous vegetables (for example, eggplant, tomato, pimento, pepper,or potato),

cucurbitaceous vegetables (for example, cucumber, pumpkin, zucchini,water melon, or melon),

cruciferous vegetables (for example, Japanese radish, white turnip,horseradish, kohlrabi, Chinese cabbage, cabbage, leaf mustard, broccoli,or cauliflower),

asteraceous vegetables (for example, burdock, crown daisy, artichoke, orlettuce),

liliaceous vegetables (for example, green onion, onion, garlic, orasparagus),

ammiaceous vegetables (for example, carrot, parsley, celery, orparsnip),

chenopoddaceous vegetables (for example, spinach, or Swiss chard),

lamiaceous vegetables (for example, Perilla frutescens, mint, or basil),

strawberry, sweet potato, Dioscorea japonica, colocasia, or the others;

Flowers:

Ornamental Foliage Plants:

Lawn:

Fruits:

pomaceous fruits (for example, apple, pear, Japanese pear, Chinesequince, or quince),

stone fleshy fruits (for example, peach, plum, nectarine, Prunus mume,cherry fruit, apricot, or prune)

citrus fruits (for example, Citrus unshiu, orange, lemon, lime, orgrapefruit),

nuts (for example, chestnut, walnuts, hazelnuts, almond, pistachio,cashew nuts, or macadamia nuts), berry fruits (for example, blueberry,cranberry, blackberry or raspberry),

grape, kaki persimmon, olive, Japanese plum, banana, coffee, date palm,coconuts, and the others;

Trees Other than Fruit Trees:

tea, mulberry, flowering plant, roadside trees (for example, ash, birch,dogwood, Eucalyptus, Ginkgo biloba, lilac, maple, Quercus, poplar, Judastree, Liquidambar formosana, plane tree, zelkova, Japanese arborvitae,fir wood, hemlock, juniper, Pinus, Picea, and Taxus cuspidate); and theothers.

The above plants also include a plant that can be generated by a naturalcrossbreeding, a plant that can be generated by mutations, an F1 hybridplant, and a genetically modified crop. Examples of the geneticallymodified crop include a plant modified to have the resistance to HPPD(4-hydroxyphenylpyruvate dioxygenase) inhibitors such as isoxaflutole,ALS (acetolactate synthase) inhibitors such as imazethapyr andthifensulfuron-methyl, EPSP (5-enolpyruvoylshikimate-3-phosphatesynthase) inhibitors, glutamine synthetase inhibitors, PPO(protoporphyrinogen oxidase) inhibitors, or herbicides such asbromoxynil and dicamba; a plant modified to synthesize a selective toxinknown to be produced in Bacillus such as Bacillus thuringiensis; and aplant modified to have a specific insecticidal activity by synthesizinga gene fragment partially corresponding to an endogenous gene derivedfrom a harmful insect to induce the gene silencing (RNAi; RNAinerference) in the target harmful insect.

Examples of applying an effective amount of the compound Z of thepresent invention or the composition of the present invention to plantor soils for cultivating plants include a method of applying aneffective amount of the compound Z of the present invention or thecomposition of the present invention to a stem and leaf, a flower, aseedling, an ear of a plant; a method of applying an effective amount ofthe compound Z of the present invention or the composition of thepresent invention to a seed or a bulb such as seed tuber (for example, aseed disinfection, a seed soaking, or a seed coating), or a method ofapplying an effective amount of the compound Z of the present inventionor the composition of the present invention to soils before plantingplants or soils after planting plants.

Specific examples of applying an effective amount of the compound Z ofthe present invention or the composition of the present invention to astem and leaf, a flower, fruit, an ear of a plant include a method forapplying an effective amount of the compound Z of the present inventionor the composition of the present invention to a surface of plant (forexample, foliage application, and trunk application), a method forapplying an effective amount of the compound Z of the present inventionor the composition of the present invention to a flower or a whole plantat flowering times including before flowering, during flowering, andafter flowering, and a method for applying an effective amount of thecompound Z of the present invention or the composition of the presentinvention to an ear or a whole grain at sprouting season of grain.

Also, examples a method of controlling harmful arthropods by applying aneffective amount of the compound. Z of the present invention or thecomposition of the present invention soils before planting plants orafter planting plants include a method of applying an effective amountof the compound Z of the present invention or the composition of thepresent invention to a root part of a crop to be protected from damagesuch as ingestion by harmful arthropods, and a method controllingharmful arthropods that ingest a plant by permeating and transferring aneffective amount of the compound Z of the present invention or thecomposition of the present invention from a root into the interior ofthe plant body. More specifically, examples of the method of applying aneffective amount of the compound of the present invention or thecomposition of the present invention to soils before planting plants orafter planting plants include planting hole treatment (spraying intoplanting holes, soil mixing after planting hole treatment), plant foottreatment (plant foot spraying, soil mixing after plant foot treatment,irrigation at plant foot, plant foot treatment at a later seedingraising stage), planting furrow treatment (planting furrow spraying,soil mixing after planting furrow treatment), planting row treatment(planting row spraying, soil mixing after planting row treatment,planting row spraying at a growing stage), planting row treatment at thetime of soaring (planting row spraying at the time of sowing, soilmixing after planting row treatment at the time of sowing), broadcasttreatment (overall soil surface spraying, soil mixing after broadcast teatment), side-article treatment, treatment of water surface(application to water surface, application to water surface afterflooding), other soil spraying treatment (spraying of a granularformulation on leaves at a growing stage, spraying under a canopy oraround a tree stem, spraying on the soil surface, mixing with surfacesoil, spraying into seed holes, spraying on the ground surfaces offurrows, spraying between plants), other irrigation treatment (soilirrigation, irrigation at seedling raising stage, drug solutioninjection treatment, irrigation of a plant part just above the ground,drug solution drip irrigation, chemigation), seedling raising boxtreatment (spraying into a seedling raising box, irrigation of aseedling raising box, flooding into a seedling raising box with drugsolution), seedling raising tray treatment (spraying on a seedlingraising tray, irrigation of a seedling raising tray, flooding into aseedling raising tray with drug solution), seedbed treatment (sprayingon a seedbed, irrigation of a seedbed, spraying on a lowland ricenursery, immersion of seedlings), seedbed soil incorporation treatment(mixing with seedbed soil, mixing with seedbed soil before sowing,spraying at sowing before covering with soils, spraying at sowing aftercovering with soils, mixing with covering soil, and other treatment(mixing with culture soil, plowing under, mixing with surface soil,mixing with soil at the place where raindrops fall from a canopy,treatment at a planting position, spraying of a granule formulation onflower clusters, mixing with a paste fertilizer).

A bulb described herein represents discoid stems, corms, rhizomes,tubers, tuberous, seed tubers, and tuberous roots. A method forcontrolling harmful arthropods by applying an effective amount of thecompound Z of the present invention or the composition of the presentinvention into a seed or a bulb include a method of applying aneffective amount of the compound Z of the present invention or thecomposition of the present invention directly into a seed or a bulb aplant to be protected from damage such as ingestion by harmfularthropods; and a method for controlling harmful arthropods that ingesta seed by applying an effective amount of the compound Z of the presentinvention or the composition of the present invention in the vicinity ofa seed or a bulb; and a method for controlling harmful arthropods thatingest a plant by permeating and transferring an effective amount of thecompound Z of the present invention or the composition of the presentinvention from a seed or a bulb into the interior of the plant body.More specifically, spraying treatment, spray coating treatment,immersion treatment, impregnation treatment, coating treatment, filmcoating treatment, and pellet coating treatment are included. Thesemethods can provide a preparation of a seed or a bulb that retain aneffective amount of the compound. Z of the present invention or thecomposition of the present invention on the surface and/or into theinterior thereof.

When the compound Z of the present invention or the composition of thepresent invention are applied to a seed or a bulb, an effective amountof the compound Z of the present invention is usually within a range of0.001 to 100 g, preferably within a range of 0.02 to 20 g, based on 1 kgof the seed or the bulb. Also an effective amount of the composition ofthe present invention is usually within a range of 0.000001 to 50 g,preferably within a range of 0.0001 to 30 g of a total amount of thecompound Z of the present invention and the active ingredient of thepresent invention, based on 1 kg of the seed or the bulb.

The plants described above are not limited specifically, as long as theyare breeds that are usually cultivated.

EXAMPLES

Hereinafter, the present invention is explained in more detail by usingPreparation Example, Formulation Example, and Test Example and the like,however, the present invention should not be limited to these examples.

In the below-mentioned Examples, when “present compound” is described,the term encompasses the “Present compound” and the “Present compoundZ”. First, the Preparation Examples of the present compound Z are shown.

Reference Preparation Example 1-1

The mixture of 6-chloro-2-fluoropyridin-3-yl boronic acid 3.75 g,2-bromo-3-(ethylsulfanyl)pyridine 4.66 g,[1,1-bis(diphenylphosphino)ferrocene]palladium dichloride 0.77 g,tripotassium phosphate 13.5 g, DMF 20 mL, and water 2 mL were stirred at80° C. under argon atmosphere for 9 hours. The reaction mixtures werecooled to room temperature, and water was added to the mixtures, and themixtures were extracted with ethyl acetate. The resulting organic layerswere dried over anhydrous sodium sulfate, and concentrated under reducedpressure. The resulting residue was subjected to a silica gel columnchromatography to obtain the intermediate compound A-1 shown below 2.9g.

Intermediate compound A-1: ¹H-NMR (CDCl₂) δ: 8.50 (1H, dd), 7.85 (1H,dd), 7.75 (1H, dd), 7.35-7.31 (2H, m), 2.88 (2H, q), 1.26 (3H, t).

Reference Preparation Example 1-2

The process was carried out by using 6-chloro-4-fluoropyridin-3-ylboronic acid pinacol ester in place of 6-chloro-2-fluoropyridin-3-ylboronic acid according to the method described in Reference Preparationobtain the intermediate compound B-1 shown below.

Intermediate compound B-1: ¹H-NMR (CDCl₃) δ: 8.53 (1H, dd), 8.46 (1H,d), 7.76 (1H, dd), 7.34 (1H, dd), 7.20 (1H, d), 2.87 (2H, q), 1.25 (3H,t).

Reference Preparation Example 2-1

To the mixtures of the intermediate compound A-1 2.9 g, sodium hydride(60% in oil) 0.43 g and DMF 10 mL were added dropwise benzyl alcohol 1.1mL under ice-cooling, and the reaction mixtures were stirred at 0° C.for 5 h. Water was added to the mixtures, and the mixtures wereextracted with ethyl acetate. The resulting organic layers were driedover anhydrous sodium sulfate, and concentrated under reduced pressure.The resulting residue was subjected to a silica gel columnchromatography to obtain the intermediate compound A-2 shown below 3.31g.

Intermediate compound A-2: ¹H-NMR (CDCl₃) δ: 8.47 (1H, dd), 7.69 (1H,dd), 7.59 (1H, d), 7.31-7.26 (6H, m), 7.04 (1H, d), 5.42 (2H, s), 2.78(2H, q), 1.17 (3H, t).

Reference Preparation Example 2-2

The compound which was prepared according to the method described inReference Preparation Example 2-1 and its physical property value areshown below.

Intermediate compound B-2: ¹H-NMR. (CDCl₃) δ: 8.50 (1H, dd), 8.22 (1H,s), 7.71 (1H, dd), 7.31-7.29 (6H, m), 6.96 (1H, s), 5.14 (2H, s), 2.81(2H, q), 1.20 (3H, t).

Reference Preparation Example 2-3

To the mixtures of the intermediate compound B-2 0.53 g and chloroform15 mL was added mCPBA (purity 70%) 0.8 g under ice-cooling, and themixtures were stirred at 0° C. to room temperature for 5 hours. To themixtures was added aqueous sodium thiosulfate solution, and the mixtureswere extracted with chloroform. The resulting organic layers were washedwith saturated aqueous sodium bicarbonate solution, dried over anhydroussodium sulfate, and concentrated under reduced pressure. The resultingresidue was subjected to a silica gel column chromatography to obtainthe intermediate compound B-3 shown below 0.35 g.

Intermediate compound B-3: ¹H-NMR (CDCl₃) δ: 8.92 (1H, dd), 8.42 (1H,dd), 8.19 (1H, s), 7.57 (1H, dd), 7.31-7.29 (3H, m), 7.23-7.21 (2H, m),7.01 (1H, s), 5.10 (2H, s), 2.90 (2H, q), 1.10 (3H, t).

Reference Preparation Example 2-4

The compound which was prepared according to the method described inReference Preparation Example 2-3 and its physical property value areshown below.

Intermediate compound A-6: ¹H-NMR (CDCl₃) δ: 8.91 (1H, dd), 8.40 (1H,dd), 7.63 (1H, d), 7.55 (1H, dd), 7.30-7.24 (5H, m), 7.08 (1H, d),5.50-5.28 (2H, m), 2.78-2.71 (2H, m), 0.92 (3H, t).

Reference Preparation Example 3-1

The mixtures of the intermediate compound A-2 3.31 g and concentratedhydrochloric acid 10 mL was stirred at 80° C. for 1.5 hours. Themixtures were cooled to room temperature, and then to the mixtures wasadded 2M aqueous sodium hydroxide solution to adjust the pH 4. Theprecipitated solids were collected by filtration to obtain theintermediate compound A-3 shown below 2.03 g.

Intermediate compound A-3: ¹H-NMR (CDCl₃) δ: 8.44 (1H, d), 8.39 (1H,dd), 7.85 (1H, dd, J=8.1, 1.5 Hz), 7.30 (1H, dd), 6.94 (1H, d), 2.94(2H, q), 1.29 (3H, t).

Reference Preparation Example 3-1 A

The compounds which were prepared according to the method described inReference Preparation Example 3-1 and their physical property values areshown below.

Intermediate compound A-7: ¹H-NMR (CDCl₃) δ: 8.91 (1H, dd), 8.41 (1H,dd), 7.64 (1H, d), 7.58 (1H, dd), 6.68 (1H, d), 3.37 (2H, q), 1.30 (3H,t).

Intermediate compound A-21: ¹H-NMR (CDCl₃) δ: 8.84 (1H, d), 8.37 (1H,d), 7.59 (1H, d), 6.64 (1H, d), 3.40 (2H, q), 1.33 (3H, t).

Intermediate compound A-25: ¹H-NMR (CDCl₃) δ: 9.13 (1H, s), 8.61 (1H,s), 7.62 (1H, d), 6.64 (1H, d), 3.46-3.43 (2H, m), 1.35 (3H, t).

Reference Preparation Example 3-2

A mixture of the intermediate compound A-38 10 g and concentratedhydrochloric acid 30 mL was stirred under reflux for 16 hours. Themixture was cooled to room temperature, and thereto was added toluene,and the mixture was concentrated under reduced pressure. The resultingsolids were washed with hexane to obtain the intermediate compound A-39shown below 8 g.

Intermediate compound A-39: ¹H-NMR (CDCl₃) δ: 8.63 (1H, d), 7.87-7.85(1H, m), 7.73-7.68 (2H, m), 7.04 (1H, d), 3.18-3.02 (2H, m), 1.07 (3H,t).

Reference Preparation Example 3-2A

The compounds which were prepared according to the method described inReference Preparation Example 3-2 and their physical property values areshown below.

Intermediate compound B-16: ¹H-NMR (CDCl₃) δ: 8.87 (1H, s), 8.34 (1H,s), 8.26 (1H, s), 7.89 (1H, s), 3.24-3.18 (2H, m), 1.30 (3H, t).

Intermediate compound B-20: ¹H-NMR (CDCl₃) δ: 9.16 (1H, s), 8.60 (1H,s), 8.29 (1H, s), 7.66 (1H, s), 3.25-3.19 (2H, m), 1.32-1.26

Intermediate Compound A-44

Intermediate Compound A-47

Reference Preparation Example B-3

The mixtures of the intermediate compound B-3 0.35 g, 10%palladium-carbon 100 mg, and ethyl acetate 5 mL were stirred underhydrogen atmosphere for 3 hours. The reaction mixtures were filteredthrough Celite (Registered Trademark), concentrated under reducedpressure to obtain the intermediate compound B-4 shown below 0.11 g.

Intermediate compound B-4: ¹H-NMR (CDCl₃) δ: 8.87 (1H, dd), 8.61 (1H,d), 8.54 (1H, s), 7.62 (1H, dd), 6.94 (1H, s), 3.08 (2H, q), 1.18 (3H,t).

Reference Preparation Example 4-1

The mixtures of the intermediate compound A-3 1.0 g, methyl iodide 0.28mL, cesium carbonate 1.82 g, and DMF 10 mL were stirred at 0° C. for 3.5hours. Water was added to the mixtures, and the mixtures were extractedwith ethyl acetate. The resulting organic layers were dried overanhydrous sodium sulfate, and concentrated under reduced pressure. Theresulting residue was subjected to a silica gel column chromatography toobtain the intermediate compound A-4 shown below 0.55 g.

Intermediate compound A-4: ¹H-NMR (CDCl₃) δ: 8.45 (1H, dd), 7.69 (1H,dd), 7.42 (1H, d, J=7.5 Hz), 7.24 (1H, dd), 6.43 (1H, d), 3.76 (3H, s),2.88 (2H, q), 1.26 (3H, t).

Reference Preparation Example 4-2

The compounds which were prepared according to the method described inReference Preparation Example 4-1 and their physical property values areshown below.

Intermediate compound A-5: ¹H-NMR (CDCl₃) δ: 8.45 (1H, d), 7.70 (1H, d),7.40 (1H, d), 7.23 (1H, dd), 6.40 (1H, d), 4.39-4.38 (2H, m), 2.91-2.85(2H, m), 1.37 (3H, t), 1.25 (3H, t)

Intermediate compound B-5: ¹H-NMR (CDCl₃) δ: 8.93 (1H, dd), 8.45 (1H,dd), 8.16 (1H, 7.60 (1H, dd), 6.95 (1H, s), 3.83 (3H, s), 2.93 (2H, q),1.19 (3H, t).

Intermediate Compound A-40

The compounds represented by formula (MA-1):

wherein the combination of R⁵, A¹, R³ and n represents any combinationsindicated in Table 17.

TABLE 17 Intermediate compound R⁵ A¹ R³ n A-8 Pr N H 2 A-9 i-Pr N H 2A-10 Bu N H 2 A-11 CH₂CH═CH₂ N H 2 A-12 CH₂C≡CH N H 2 A-13 CH₂c-Pr N H 2A-14 CH₂CF₂CF₃ N H 2 A-15 Bn N H 2 A-16

N H 2 A-22 Me N Cl 2 A-26 Me N CF₃ 2 A-37 Me N H 2 A-42 Et N CF₃ 2

Intermediate compound A-8: ¹H-NMR (CDCl₃) δ: 8.87 (1H, dd), 8.34 (1H,dd), 7.52 (1H, dd), 7.39 (1H, d), 6.46 (1H, d), 4.25 (2H, m), 3.53-3.42(2H, m), 1.85-1.74 (2H, 1.33 (3H, t), 1.01 (3H, t).

Intermediate compound A-9: ¹H-NMR (CDCl₃) δ: 8.86 (1H, dd), 8.33 (1H,dd), 7.51 (1H, dd), 7.33 (1H, t), 6.42 (1H, q), 5.18-5.14 (1H, m),3.55-3.41 (2H, m), 1.65-1.61 (6H, m), 1.33 (3H, t).

Intermediate compound A-10: ¹H-NMR (CDCl₃) δ: 8.87 (1H, dd), 8.34 (1H,dd), 7.52 (1H, dd), 7.39 (1H, d), 6.46 (1H, d), 4.28 (2H, t), 3.48 (2H,q), 1.78-1.69 (2H, m), 1.45-1.42 (2H, m), 1.33 (3H, t), 0.97 (3H, t).

Intermediate compound A-11: ¹H-NMR (CDCl₃) δ: 8.87 (1H, dd), 8.33 (1H,dd), 7.52 (1H, dd), 7.43 (1H, d), 6.49 (1H, d), 5.98-5.89 (1H, m),5.27-5.20 (2H, m), 4.95-4.89 (2H, m), 3.47 (2H, q), 1.32 (3H, t).

Intermediate compound A-12: ¹H-NMR (CDCl₃) δ: 8.87 (1H, dd), 8.35 (1H,dd), 7.53 (1H, dd), 7.45 (1H, d), 6.51 (1H, d), 5.11-5.00 (2H, m), 3.47(2H, q), 2.27 (1H, t), 1.33 (3H, t).

Intermediate compound A-13: ¹H-NMR (CDCl₃) δ: 8.87 (1H, dd), 8.35 (1H,dd), 7.52 (1H, dd), 7.40 (1H, d), 6.47 (1H, d), 4.23-4.20 (2H, m),3.48-3.44 (2H, m), 1.33 (4H, t), 0.56-0.52 (4H, m).

Intermediate compound A-14: ¹H-NMR (CDCl₃) δ: 8.88 (1H, dd), 8.35 (1H,dd), 7.55 (1H, dd), 7.47 (1H, d), 6.56 (1H, d), 5.03 (2H, br s), 3.40(2H, q), 1.32 (3H, t).

Intermediate compound A-15: ¹H-NMR (CDCl₃) δ: 8.87 (1H, dd), 8.33 (1H,dd), 7.52 (1H, dd), 7.45 (1H, d), 7.33-7.27 (5H, m), 6.51 (1H, d),5.64-5.42 (2H, m), 3.40-3.37 (2H, m), 1.25 (3H, t).

Intermediate compound A-16: ¹H-NMR (CDCl₃) δ: 8.88 (1H, dd), 8.36 (1H,dd), 7.66 (1H, s), 7.55 (1H, dd), 7.44 (1H, d), 6.52 (1H, d), 5.57-5.47(2H, m), 3.54-3.37 (2H, m), 1.36 (3H, t).

Intermediate compound A-22: ¹H-NMR (CDCl₃) δ: 8.81 (1H, d), 8.33 (1H,d), 7.41 (1H, d), 6.50 (1H, d), 3.74 (3H, s), 3.50-3.46 (2H, m), 1.35(3H, t).

Intermediate compound A-26: ¹H-NMR (CDCl₃) δ: 9.10 (1H, s), 8.57 (1H,s), 7.46 (1H, d), 6.53 (1H, d), 3.75 (3H, s), 3.52 (2H, q), 1.36 (3H,t).

Intermediate compound A-37: ¹H-NMR (CDCl₃) δ: 8.86 (1H, d), 8.34 (1H,d), 7.52-7.4 (1H, m), 7.40 (1H, d), 6.48 (1H, d), 3.72 (3H, s), 3.43(2H, q), 1.31 (3H, t).

Intermediate compound. A-42: ¹H-NMR (CDCl₃) δ: 9.10 (1H, d), 8.55 (1H,d), 7.44 (1H, d), 6.50 (1H, d), 4.38 (2H, q), 3.61-3.54 (2H, m), 1.38(3H, t), 1.37 (3H, t).

Intermediate compound A-45: ¹H-NMR (CDCl₃) δ: 7.93 (1H, d), 7.30 (1H,d), 6.52-6.40 (2H, m), 3.70 (3H, s), 3.37-3.30 (2H, m), 3.13 (6H, s),1.27 (3H, t).

Intermediate compound A-48

The compounds represented by formula (MB-1):

wherein the combination of R⁵, A¹, R³ and n represents any combinationsindicated in Table 18.

TABLE 18 Intermediate compound R⁵ A¹ R³ n B-9 Et N H 2 B-10 Pr N H 2B-11 Bu N H 2 B-12 CH₂CH═CH₂ N H 2 B-13 CH₂c-Pr N H 2 B-17 Me N Cl 2B-21 Me N CF₃ 2 B-22 i-Pr N H 2 B-23 Bn N H 2 B-24 CH₂CH₂CF₃ N H 2

Intermediate compound B-9: ¹H-NMR (CDCl₃) δ: 8.88 (1H, dd), 8.38 (1H,dd), 7.56 (1H, s), 7.53 (1H, dd), 6.62 (1H, s), 4.15-4.09 (2H, m),3.49-3.39 (2H, m), 1.48 (3H, t), 1.30 (3H, t).

Intermediate compound B-10: ¹H-NMR (CDCl₃) δ: 8.88 (1H, dd), 8.38 (1H,dd), 7.53 (1H, s), 7.52 (1H, dd), 6.61 (1H, s), 4.10-3.92 (2H, m),3.51-3.36 (2H, m), 1.93-1.84 (2H, m), 1.30 (3H, t), 1.01 (3H, t).

Intermediate compound B-11: ¹H-NMR (CDCl₃) δ: 8.88 (1H, dd), 8.38 (1H,dd), 7.52 (2H, dd), 6.62 (1H, s), 4.07 (2H, s), 3.44 (2H, s), 1.84-1.81(2H, m), 1.43-1.40 (2H, m), 1.30 (3H, t), 0.98 (3H, t).

Intermediate compound B-12: ¹H-NMR (CDCl₃) δ: 8.88 (1H, dd), 8.37 (1H,dd), 7.54-7.52 (2H, m), 6.63 (1H, s), 6.00-5.90 (1H, m), 5.39 (1H, d),5.27 (1H, d), 4.70-4.64 (2H, m), 3.49-3.44 (2H, m), 1.31 (3H, t).

Intermediate compound B-13: ¹H-NMR (CDCl₃) δ: 8.89 (1H, dd), 8.39 (1H,dd), 7.63 (1H, s), 7.53 (1H, dd), 6.63 (1H, s), 4.01-3.88 (2H, m),3.50-3.37 (2H, m), 1.33-1.28 (4H, m), 0.74-0.70 (2H, m), 0.45 (2H, m).

Intermediate compound B-17: ¹H-NMR (CDCl₃) δ: 8.80 (1H, d), 8.34 (1H,d), 7.53 (1H, s), 6.63 (1H, s), 3.77 (3H, s), 3.57-3.49 (2H, m), 1.35(3H, t).

Intermediate compound B-21: ¹H-NMR (CDCl₃) δ: 9.16 (1H, d), 8.68 (1H,d), 8.17 (1H, s), 6.98 (1H, s), 3.85 (3H, 2.96 (2H, q), 1.22 (3H, t).

Intermediate compound B-21: ¹H-NMR (CDCl₃) δ: 8.90 (1H, dd), 8.41 (1H,dd), 7.64 (1H, s), 7.53 (1H, dd), 6.62 (1H, s), 5.02-4.96 (1H, m),3.41-3.29 (2H, m), 1.49 (6H, d), 1.29-1.25 (3H, m).

Intermediate compound B-23: ¹H-NMR (CDCl₃) δ: 8.87 (1H, dd), 8.37 (1H,dd), 7.62 (1H, s), 7.52 (1H, dd), 7.43-7.33 (3H, m), 7.26-7.22 (2H, m),6.65 (1H, s), 5.27-5.23 (2H, m), 3.52-3.41 (2H, m), 1.32 (3H, t).

Intermediate compound B-24: ¹H-NMR (CDCl₃) δ: 8.89 (1H, dd), 8.38 (1H,dd), 7.54 (1H, dd), 7.53 (1H, s), 6.64 (1H, s), 4.41-4.22 (2H, m),3.44-3.37 (2H, m), 2.77-2.63 (2H, m), 1.30 (3H, t).

Reference Preparation Example 5

The mixtures of the intermediate compound A-7 0.4 g, copper(II) acetate0.48 g, cesium carbonate 0.43 g, cyclopropyl boronic acid 0.23 g,pyridine 0.3 mL, and xylene 2.7 mL were stirred at 110° C. for 20 hours.The resulting mitures were cooled to room temperature, and the mixtureswere filtered through Celite (Registered trademark) and the filtrateswere concentrated under reduced pressure. The resulting residue wassubjected to a silica gel column chromatography to obtain theintermediate compound A-17 shown below 37 mg.

Intermediate compound A-17: ¹H-NMR (CDCl₃) δ: 8.86 (1H, dd), 8.32 (1H,dd), 7.51 (1H, dd), 7.38 (1H, d), 6.43 (1H, d), 3.52 (2H, q), 2.99-2.95(1H, m), 1.36 (3H, t), 1.32-1.31 (2H, m), 1.03-1.00 (2H, m).

Reference Preparation Example 6-1

To the mixtures of methyl 6-chloro-2-methoxy nicotinic acid 0.5 g, ethylmethyl sulfone 5 mL and THF 12 mL was added dropwise lithium hexamethyldisilazide (1.1 M THF solution) 5 mL at −10° C. The resulting mixtureswere stirred for 20 minutes, and thereto was added 6N hydrochloric acid1 mL.

Water was added to the resulting mixtures, and the mixtures wereextracted with ethyl acetate. The resulting organic layers were driedover anhydrous sodium sulfate, and concentrated under reduced pressure.The resulting residue was subjected to a silica gel columnchromatography to obtain the intermediate compound A-18 shown below 0.6cf.

Intermediate compound A-18: ¹H-NMR (CDCl₃) δ: 8.14 (1H, d), 7.06 (1H,d), 4.74 (2H, s), 4.13 (3H, s), 3.28 (2H, q), 1.44 (3H, t).

Reference Preparation Example 6-2

The compound which was prepared according to the method described inReference Preparation Example 6-1 and its physical property value areshown below.

Intermediate compound B-6: ¹H-NMR (CDCl₃) δ: 8.69 (1H, s), 6.98 (1H, s),4.67 (2H, s), 4.06 (3H, s), 3.26 (2H, q), 1.44 (3H, t).

Intermediate compound C-2: ¹H-NMR (CDCl₃) δ: 8.81 (1H, s), 4.68 (2H, s),4.17 (3H, s), 3.26 (2H, q), 2.61 (3H, s), 1.44 (5H, t).

Reference Preparation Example 7-1

The mixtures of theintermediate compound A-18 2.96 g, ammonium acetate5.0 g, acetic acid 0.15 mL, and methanol 13 mL were stirred at 65° C.for 6 hours. The resulting mixtures were cooled to room temperature, andthereto was added aqueous sodium hydroxide solution. The precipitatedsolids were filtered, and the obtained solids were washed with water,concentrated under reduced pressure to obtain the intermediate compoundA-19 shown below 2.7 g.

Intermediate compound A-19: ¹H-NMR (CDCl₃) δ: 7.67 (1H, d), 6.98 (1H,d), 6.11 (2H, br s), 4.83 (1H, s), 4.02 (3H s), 3.07 (2H, q), 1.41 (3H,t).

Reference Preparation Example 7-2

The compound which was prepared according to the method described inReference Preparation Example 7-1 and its physical property value areshown below.

Intermediate compound B-14: ¹H-NMR (CDCl₃) δ: 8.28 (1H, s), 6.91 (1H,s), 5.95 (2H, 4.81 (1H, s), 3.95 (3H, s), 3.08 (2H, q), 1.42 (3H, t).

Intermediate compound C-3: ¹H-NMR (CDCl₃) δ: 8.38 (1H, s), 6.08 (2H,br), 4.87 (1H, s), 4.06 (3H, s), 3.08 (2H, q), 2.58 (3H, s), 1.41 (3H,t).

Reference Preparation Example 8-1

The mixtures of sodium hydride (60% in oil) 0.90 g and DMF 25 mL werecooled to 0° C., and thereto was added dropwise the intermediatecompound A-19 2.71 g that was dissolved in DMF 5 mL. The resultingmixtures were stirred at 0° C. for 30 minutes, and thereto was thenadded 2-chloro-1,3-bis(dimethylamino)trimethinium hexafluorophoshate6.60 g, and the mixtures were stirred at 60° C. for 2 hours. Theresulting mixtures were cooled to room temperature, and, water was addedthereto, and the mixtures were extracted with ethyl acetate. Theresulting organic layers were dried over anhydrous sodium sulfate andconcentrated under reduced pressure. The esulting residue was subjectedto a silica gel column chromatography to obtain the intermediatecompound A-20 shown below 2.48 g Here2-chloro-1,3-bis(dimethylamino)trimethinium hexafluo ophosphate wasprepared according to the method described in J. Org. chem., 2000, 65,4571.

Intermediate compound A-20: ¹H-NMR (CDCl₃) δ: 8.84 (1H, d), 8.43 (1H,d), 7.60 (1H, d), 7.06 (1H, d), 3.91 (3H, s), 2.97-2.87 (2H, m), 1.21(3H, t).

Reference Preparation Example 8-2

The compound which was prepared according to the method described inReference Preparation Example 8-1 and its physical property value areshown below.

Intermediate compound B-15: ¹H-NMR (CDCl₃) δ: 8.86 (1H, d), 8.43 (1H,d), 8.14 (1H, s), 6.95 (1H, s), 3.83 (3H, s), 2.93 (2H, q), 1.21 (3H,t).

Reference Preparation Example 8-3

The compounds which were prepared by using2-trifluoromethyl-1,3-bis(dimethylamino)trimethinium hexafluorophosphatein place of 2-chloro-1,3-bis(dimethylamino)trimethiniumhexafluorophosphate according to the method described in ReferencePreparation Example 8-1 and their physical property values are shownbelow.

Intermediate compound A-24: ¹H-NMR (CDCl₃) δ: 9.14 (1H, d), 8.69 (1H,d), 7.62 (1H, d), 7.09 (1H, d), 3.92 (3H, s), 2.98-2.93 (2H, m), 1.22(3H, t).

Intermediate compound B-19: ¹H-NMR (CDCl₃) δ: 9.16 (1H, d), 8.68 (1H,d), 8.17 (1H, s), 6.98 (1H, s), 3.85 (3H, s), 2.96 (2H, q), 1.22 (3H,t).

Intermediate compound C-4: ¹H-NMR (CDCl₃) δ: 9.15 (1H, 8.67 (1H, d),8.29 (1H, s), 3.97 (3H, s), 3.02-2.99 (2H, m), 2.62 (3H, s), 1.23 (3H,t).

Reference Preparation Example 9-1

To the mixtures of DMF 0.84 mL and chloroform 24 mL was added dropwiseoxalyl chloride 0.92 mL under ice-cooling. The resulting mixtures werestirred for 15 minutes under ice-cooling, and then stirred at roomtemperature for 2 hours. The resulting mixtures were cooled again underice-cooling, and thereto was added butyl vinyl ether 2.8 mL, and themixtures were stirred for 1 hour. The resulting mixtures were warmed toroom temperature, and stirred for 2 hours. To the resulting mixtureswere added the intermediate compound B-6 1.00 g and triethyl amine 3.5mL successively under ice-cooling. The resulting mixtures were stirredat room temperature for 3 hours, and thereto was added saturated aqueousammonium chloride solution, and the mixtures were extracted withchloroform. The resulting organic layers were dried over sodium sulfate,filtered and concentrated under reduced pressure. To the resultingresidues were added ethanol 13 mL and 30% ammonia water 1.4 mLsuccessively. The resulting mixtures were stirred at 60° C. for 9 hours,and concentrated under reduced pressure. Water was added to theresulting residues, and the mixtures were extracted with ethyl acetate.The resulting organic layers were washed with saturated brine, driedover anhydrous sodium sulfate, filtered, and concentrated under reducedpressure. To resulting residue were added to ethanol 13 mL and 30aqueous ammonia 1.4 mL successively. The resulting mixture was stirredat 60° C. for 9 hours, and concentrated under reduced pressure. Waterwas added to the resulting residue, and the mixture was extracted withethyl acetate. The resulting organic layer was washed with saturatedbrine, dried over anhydrous sodium sulfate, filtered, and concentratedunder reduced pressure. The resulting residue was subjected to a silicagel column chromatography to obtain the intermediate compound B-7 shownbelow 0.87 g.

Intermediate compound B-7: ¹H-NMR (CDCl₃) δ: 8.93 (1H, dd), 8.45 (1H,dd), 8.16 (1H, s), 7.59 (1H, dd), 6.95 (1H, s), 3.83 (3H, s), 2.93 (2H,q), 1.19 (3H, t).

Reference Preparation Example 9-2

The compound which was prepared according to the method described inReference Preparation Example 9-1 and its physical property value areshown below,

Intermediate compound A-27: ¹H-NMR (CDCl₃) δ: 8.91 (1H, dd), 8.45 (1H,dd), 7.61 (1H, d), 7.57 (1H, dd), 7.06 (1H, d), 3.91 (3H, s), 2.96-2.88(2H, m), 1.19 (3H, t).

Reference Preparation Example 10-1

The mixtures of the Present compound A-18 (described in PreparationExample 1) 0.45 g, bis(pinacolato)diboron 0.37 g,tris(dibenzylideneacetone)dipalladium(0) 0.09 g,2-dicyclohpxylphosphino-2′,4′,6′-triisopropylbiphenyl 0.14 g, potassiumacetate 0.29 g, and 1,2-dimethoxyethane 9 mL were stirred at 70° C.under nitrogen atmosphere for 30 minutes. Water was added to theresulting mixtures at room temperature, and the mixtures were extractedwith ethyl acetate. The resulting organic layers were washed withsaturated brine, dried over anhydrous sodium sulfate, and concentratedunder reduced pressure. The resulting solids were washed with hexane toobtain the intermediate compound A-23 shown below 0.52 g.

Intermediate compound A-23: ¹H-NMR (CDCl₃) δ: 9.13 (1H, d), 8.69 (1H,d), 7.51 (1H, d), 5.67 (1H, d), 4.51 (2H, t), 3.52 (3H, s), 3.49-3.43(2H, m), 1.37 (12H, s), 1.34 (3H, t).

Reference Preparation Example 10-2

The compound which was prepared according to the method described inReference Preparation Example 10-1 and its physical property value areshown below.

Intermediate compound B-18: ¹H-NMR (CDCl₃) δ: 9.12 (1H, d), 8.69 (1H,d), 7.36 (1H,), 5.86 (1H, s), 4.47 (2H, t), 3.59-3.55 (5H, m), 1.35-1.26(15H, m).

Intermediate Compound A-30

Intermediate compound B-26: ¹H-NMR (CDCl₃) δ: 7.66 (1H, s), 3.42 (3H,s), 3.33 (3H, s), 1.32 (12H, s).

Reference Preparation Example 11-1

To the mixtures of 3-bromo-6-chloro-1-methylpyridin-2(1H)-one 27.28 g,cesium carbonate 47.94 g, and DMF 100 mL was added dropwise2,2,3,3,3-pentafluoro-1-propanol 19.32 g under ice-cooling, and themixtures were stirred at room temperature for 3 hours. Water was addedto the resulting mixtures, and the mixtures were extracted with ethylacetate. The resulting organic layers were dried over anhydrous sodiumsulfate, and concentrated under reduced pressure. The resulting residueswere washed with water and hexane successively to obtain theintermediate compound A-28 shown below 39.41 g.

Intermediate compound A-28: ¹H-NMR (CDCl₃) δ: 7.68 (1H, d), 5.46 (1H,d), 4.46 (2H, t), 3.55 (3H, s).

Reference Preparation Example 11-2

The compounds which were prepared according to the method described inReference Preparation Example 11-1 and their physical property valuesare shown below.

Intermediate compound A-29: ¹H-NMR (CDCl₃) δ: 7.93 (1H, s), 4.85 (2H,t), 3.52 (3H, s).

Intermediate compound A-41: ¹H-NMR (CDCl₃) δ: 8.46 (1H, d), 7.91 (1H,d), 7.54 (1H, d), 7.43 (1H, t), 5.72 (1H, d), 4.52 (2H, t), 3.53 (3H,s), 3.11-3.06 (2H, m), 1.23 (3H, t).

Reference Preparation Example 12-1

The mixtures of the intermediate compound A-28 2.0 g,2-fluoro-4-(trifluoromethyl)phenyl boronic acid 1.24 g,[1,1′-bis(diphenylphosphino)ferrocene]palladium(II) dichloride additive0.44 g, tripotassium phosphate 3.79 g, 1,2-dimethoxyethane 15 mL andwater 1.5 mL were stirred at 80° C. for 3 hours. The resulting mixtureswere stood to cool to room temperature, and water was then addedthereto, and the mixtures were extracted with ethyl acetate. Theresulting organic layers were dried over anhydrous sodium sulfate, andconcentrated under reduce pressure. The resulting residue was subjectedto a silica gel column chromatography to obtain the intermediatecompound A-31 shown below 0.53 g.

Intermediate compound A-31: ¹H-NMR (CDCl₃) δ: 7.69 (1H, t), 7.51 (1H,dd), 7.44 (1H, d), 7.38 (1H, d), 5.65 (1H, d), 4.53 (2H, t), (3H, s).

Reference Preparation Example 12-2

The compound which was prepared according to the method described inReference Preparation Example 12-1 and its physical property value areshown below.

Intermediate compound A-34: ¹H-NMR (CDCl₃) δ: 7.84 (1H, d), 7.64 (1H,t), 7.47 (1H, d), 7.42 (1H, d), 4.93 (2H, t), 3.54 (3H, s).

Reference Preparation Example 13-1

To the mixtures of the intermediate compound A-31 1.13 g, sodium hydride(60%, in oil) 0.23 g, and DMF 10 mL was added dropwise ethanethiol 0.39mL under ice-cooling, and the mixtures were stirred at 60° C. for 9hours. Water was added to the resulting mixtures, and the mixtures wereextracted with ethyl acetate. The resulting organic layers were driedover anhydrous sodium sulfate, and concentrated under reduced pressure.The resulting residue waw subjected to a silica gel columnchromatography to obtain the intermediate compound A-32 shown below 0.65g.

Intermediate compound A-32: ¹H-NMR (CDCl₃) δ: 7.54 (1H, s), 7.41 (1H,dd), 7.36 (1H, d), 7.28 (1H, d), 6.12 (1H, d), 3.69 (3H, s), 3.03 (2H,q), 2.92 (2H, q), 1.46 (3H, t), 1.28 (3H, t).

Reference Preparation Example 13-2

The compound which was prepared according to the method described LnReference Preparation Example 13-1 and its physical property value areshown below.

Intermediate compound A-35: ¹H-NMR (CDCl₃) δ: 7.79 (1H, s), 7.57 (1H,s), 7.44 (1H, d), 7.34 (1H, d), 3.53 (3H, s), 3.26 (2H, q), 2.94 (2H,q), 1.44 (3H, t), 1.29 (3H, t).

Reference Preparation Example 14-1

To the mixtures of the intermediate compound A-32 0.61 g and chloroform30 mL was added mCPBA (purity 70%, containing 30% water) 1.63 g, and themixtures were stirred at 0° C. room temperature for 25 hours. To theresulting mixtures was added aqueous sodium thiosulfate solution and themixtures ere extracted with chloroform. The resulting organic layerswere washed with saturated aqueous sodium bicarbonate solution, driedover anhydrous sodium sulfate, and concentrated under reduced pressure.The resulting residue was subjected to a silica gel columnchromatography to obtain the intermediate compound A-33 shower below0.65 g.

Intermediate compound. A-33: ¹H-NMR (CDCl₃) δ: 8.30 (1H, d), 7.94 (1H,dd), 7.46 (1H, 7.42 (1H, d), 7.24 (1H, d), 3.90 (3H, s), 3.40-3.34 (4H,m), 1.42 (3H, t), 1.34 (3H, t).

Reference Preparation Example 14-2

The compound which was prepared according to the method described inReference Preparation Example 14-1 and its physical property value areshown below.

Intermediate compound A-36: ¹H-NMR (CDCl₃) δ: 9.25 (1H, s), 8.36 (1H,d), 7.92 (1H, dd), 7.51 (1H, d), 7.34 (1H, d), 3.40 (3H, s), 3.25 (2H,q), 1.29 (3H, t).

Reference Preparation Example 15

The compound which was prepared by using hydroxylamine in place of 30%ammonia water according to the method described in Reference PreparationExample 9-1 and its physical property value are shown below.

Intermediate compound A-38: ¹H-NMR (CDCl₃) δ: 8.46 (1H, d), 7.96 (1H,d), 7.62 (1H, d), 7.48 (1H, t), 7.10 (1H, d), 3.93 (3H, s), 2.87-2.72(2H, m), 1.17 (3H, t).

Reference Preparation Example 16

To a mixture of 4-methoxy-2-(methylthio)pyrimidine-5-carboxylic acid8.38 g and methanol 90 mL was added thionyl chloride 9 mL under icecooling, and the mixture was stirred at 85° C. for 3 hours. Theresulting mixture was cooled to room temperature, and concentrated. Tothe resulting residue was added aqueous saturated sodium hydrogencardonate solution, and the mixture was extracted with ethyl acetate.The resulting organic layer was dried over anhydrous sodium sulfate, andconcentrated to obtain intermediate compound C-1 shown below 4.18 g.

Intermediate compound C-1: ¹H-NMR (CDCl₃) δ: 8.82 (1H, s), 4.10 (3H, s),3.89 (3H, s), 2.59 (3H, s).

Reference Preparation Example 17

To a mixture of the intermediate compound C-4 0.51 g and acetonitrile 26mL was added dropwise a mixture of sulfuryl chloride 0.52 mL andchloroform 32 mL over 30 minutes under ice-cooling. The resultingmixture was stirred under ice-cooling for 1 hour, and the mixture waswarmed to room temperature and stirred for 6 hours. To the resultingmixture was added aqueous saturated sodium hydrogen carbonate solution,and the mixture was extracted with ethyl acetate. The resulting organiclayer was washed with saturated brine, dried over anhydrous sodiumsulfate, and concentrated. The resulting residue was subjected to asilica gel column chromatography to obtain the intermediate compound C-5shown below 0.50 g.

Intermediate compound. C-5: ¹H-NMR (CDCl₃) δ: 9.17 (1H, d), 8.66 (1H,d), 8.34 (1H, s), 4.01 (3H, s), 3.05-2.98 (2H, m), 1.26 (3H, t).

Preparation Example 1

To the mixtures of the intermediate compound A-4 0.65 g, sodium hydride(60% in oil) 0.11 g, and DMF 10 mL y added dropwise2,3,3,3-pentafluoro-1-propanol 0.28 mL under ice-cooling, and themixtures were stirred at room temperature for 3.5 hours. Water was addedto the mixtures, and the mixtures were extracted with ethyl acetate. Theresulting organic layers were dried over anhydrous sodiu 1 sulfate, andconcentrated under reduced pressure. The resulting residue was subjectedto a silica gel column chromatography (methanol:ethyl acetate=1:19) toobtain the present compound A-2 shown below 0.73 g.

Present compound A-2: ¹H-NMR (CDCl₃) δ: 8.44 (1H, dd), 7.68 (1H, dd),7.51 (1H, d), 7.22 (1H, dd), 5.63 (1H, d), 4.51 (2H, t), 3.55 (3H, 2.88(2H, q), 1.26 (3H, t).

Preparation Example A

The compounds which were prepared according to the method described inPreparation Example 1 and their physical property values are shownbelow.

The compounds represented by formula (A-1)

wherein the combination of T, R⁵, A¹, R³ and n represents anycombinations indicated in Table 19.

TABLE 19 Present com- pound T R⁵ A¹ R³ n A-4 OCH₂CF₂CF₃ Et N H 0 A-6OCH₂CF₂CHF₂ Me N H 2 A-7 OCH₂CF₂CHFCF₃ Me N H 2 A-8 OCH₂CF₂CF₂CF₃ Me N H2 A-9 OCH₂CF₂CF₂CF₂CF₃ Me N H 2 A-10 OCH₂CF₃ Me N H 2 A-11 OCH(CH₃)CF₃Me N H 2 A-17

Me N H 2 A-18 OCH₂CF₂CF₃ Me N Cl 2 A-19 OCH₂CF₂CF₃ Pr N H 2 A-20OCH₂CF₂CF₃ i-Pr N H 2 A-21 OCH₂CF₂CF₃ Bu N H 2 A-22 OCH₂CF₂CF₃ CH₂CH═CH₂N H 2 A-23 OCH₂CF₂CF₃ Me CH CF₃ 2 A-24 OCH₂CF₂CF₃ CH₂C≡CH N H 2 A-25OCH₂CF₂CF₃ CH₂c-Pr N H 2 A-27 OCH₂CF₂CF₃ CH₂CF₂CF₃ N H 2 A-32 OCH₂CF₂CF₃c-Pr N H 2 A-39 OCH₂CF₂CF₃ Me N CF₃ 2 A-41 OCH₂CF₂CF₃

N H 2 A-42 OCH₂CF₂CF₃ Bn N H 2 A-55 OCH₂CF₂CHF₂ Me N CF₃ 2 A-59OCH₂CF₂CF₃ Et N CF₃ 2 C-1 OCH₂(1-CN—c-Pr) Me N H 2 C-2 OCH₂C(Me)₂CN Me NH 2 C-7 OCH₂C(Me)₂CN Me N Cl 2 C-8 OCH₂(1-CN—c-Pr) Me N Cl 2

Present compound A-4: ¹H-NMR (CDCl₃) δ: 8.44 (1H, dd), 7.68 (1H, dd),7.49 (1H, d), 7.22 (1H, dd), 5.60 (1H, d), 4.50 (2H, t), 4.22 (2H, q),2.88 (2H, q), 1.28 (3H, t), 1.26 (3H, t).

Present compound A-6: ¹H-NMR (CDCl₃) δ: 8.86 (1H, d), 8.35 (1H, d),7.52-7.47 (2H, m), 6.12-5.85 (1H, m), 5.70 (1H, d), 4.46 (2H, t), 3.52(3H, m), 3.40 (2H, t), 1.29 (3H, t).

Present compound A-7: ¹H-NMR (CDCl₃) δ: 8.85 (1H, d), 8.34 (1H, d),7.51-7.47 (2H, m), 5.69 (1H, d), 5.14-4.97 (1H, m), 4.94-4.38 (2H, m),3.59-3.39 (5H, m), 1.29 (3H, t).

Present compound A-8: ¹H-NMR (CDCl₃) δ: 8.86 (1H, d), 8.34 (1H, d),7.52-7.47 (2H, m), 5.68 (1H, d), 4.54 (2H, t), 3.52 (3H, s), 3.42 (2H,s), 1.29 (3H, t).

Present compound A-9: ¹H-NMR (CDCl₃) δ: 8.85 (1H, d), 8.34 (1H, d),7.51-7.47 (2H, m), 5.67 (1H, d), 4.55 (2H, t), 3.52 (3H, s), 3.47-3.39(2H, m), 1.29 (3H, t).

Present compound A-10: ¹H-NMR (CDCl₃) δ: 8.85 (1H, d), 8.34 (1H, d),7.49 (2H, d), 5.66 (1H, d), 4.54 (2H, t), 3.52 (3H, s), 3.47-3.39 (2H,m), 1.29 (3H, t).

Present compound A-11: ¹H-NMR (CDCl₃) δ: 8.85 (1H, d), 8.35 (1H, d),7.49 (2H, t), 5.71 (1H, d), 4.78 (1H, t), 3.51 (3H, s), 3.44 (2H, s),1.59 (3H, d), 1.29 (3H, t).

Present compound A-17: ¹H-NMR (CDCl₃) δ: 8.88 (1H, d), 8.36 (1H, d),7.78 (1H, s), 7.56-7.54 (2H, m), 6.78 (1H, s), 6.41 (1H, d), 3.47 (2H,br), 3.35 (3H, s), 1.34 (3H, t).

Present compound A-18: ¹H-NMR (CDCl₃) δ: 8.80 (1H, d), 8.33 (1H, d),7.50 (1H, d), 5.69 (1H, d), 4.52 (2H, t), 3.53 (3H, s), 3.50-3.44 (2H,m), 1.34 (3H, t).

Present compound A-19: ¹H-NMR (CDCl₃) δ: 8.86 (1H, dd), 8.34 (1H, dd),7.50 (1H, dd), 7.49 (1H, d), 5.66 (1H, d), 4.50 (2H, dd), 4.09 (2H, t),3.51-3.44 (2H, m), 1.74-1.65 (2H, m), 1.32 (3H, t), 0.96 (3H, t).

Present compound A-20: ¹H-NMR (CDCl₃) δ: 8.86 (1H, dd), 8.35 (1H, dd),7.49 (1H, dd), 7.44 (1H, d), 5.62 (2H, d), 4.50 (2H, t), 3.48-3.41 (2H,m), 1.52-1.50 (6H, m), 1.31 (3H, t).

Present compound A-21: ¹H-NMR (CDCl₃) δ: 8.86 (1H, dd), 8.34 (1H, dd),7.49 (1H, dd), 7.48 (1H, d), 5.65 (1H, d), 4.50 (2H, t), 4.12 (2H, t),3.47 (2H, ddd), 1.67-1.61 (2H, m), 1.39-1.33 (5H, m), 0.94 (3H, t).

Present compound A-22: ¹H-NMR (CDCl₃) δ: 8.86 (1H, dd), 8.34 (1H, dd),7.51 (1H, d), 7.50 (1H, dd), 5.88 (1H, dddd), 5.68 (1H, d), 5.21-5.16(2H, 4.81-4.68 (2H, m), 4.49 (2H, t), 3.50-3.44 (2H, m), 1.30 (3H, t).

Present compound A-23: ¹H-NMR (CDCl₃) δ: 8.35 (1H, d), 7.88 (1H, dd),7.46 (1H, d), 7.39 (1H, d), 5.67 (1H, d), 4.52 (2H, t), 3.54 (3H, s),3.30 (2H, q), 1.27 (3H, t).

Present compound A-24: ¹H-NMR (CDCl₃) δ: 6.87 (1H, dd), 8.35 (1H, dd),7.55-7.50 (2H, m), 5.71 (1H, d), 4.89 (2H, dd), 4.56 (2H, t), 3.49-3.47(2H, m), 2.17-2.15 (1H, m), 1.32 (3H, t).

Present compound A-25: ¹H-NMR (CDCl₃) δ: 8.87 (1H, dd), 8.35 (1H, dd),7.52-7.48 (2H, m), 5.67 (1H, d), 4.52 (2H, t), 4.10-3.97 (2H, m),3.50-3.43 (2H,), 1.32 (3H, t,), 1.26-1.21 (1H, m), 0.53-0.47 (2H, m),0.44-0.39 (2H, m).

Present compound A-27: ¹H-NMR (CDCl₃) δ: 8.87 (1H, dd), 8.36 (1H, dd),7.57 (1H, d), 7.53 (1H, dd), 5.74 (1H, d), 4.85 (2H, br s), 4.54 (2H,t), 3.40 (2H, q), 1.31 (3H, t).

Present compound A-32: ¹H-NMR (CDCl₃) δ: 8.85 (1H, dd), 8.32 (1H, dd),7.49 (1H, dd), 7.47 (1H, d), 5.60 (1H, d), 4.48 (2H, t), 3.55-3.49 (2H,m), 2.81-2.75 (1H, m), 1.35 (3H, t), 1.24-1.20 (2H, m), 0.94-0.85 (2H,m).

Present compound A-39: ¹H-NMR (CDCl₃) δ: 9.09 (1H, s), 8.57 (1H, s),7.56 (1H, d), 5.72 (1H, d), 4.54 (2H, t), 3.54 (3H, s), 3.53 (2H, q),1.36 (3H, t).

Present compound A-41: ¹H-NMR (CDCl₃) δ: 8.88 (1H, dd), 8.36 (1H, dd),7.55 (1H, s), 7.55-7.52 (2H, m), 5.71 (1H, d), 5.35 (2H, d), 4.55 (2H,t), 3.45 (2H, dt), 1.35 (3H, t).

Present compound A-42: ¹H-NMR (CDCl₃) δ: 8.87 (1H, dd), 8.34 (1H, dd),7.53 (1H, d), 7.50 (1H, dd), 7.35-7.23 (5H, m), 5.69 (1H, d), 5.43-5.25(2H, 1), 4.45 (2H, t), 3.41 (2H, q), 1.27 (3H, t).

Present compound A-55: ¹H-NMR (CDCl₃) δ: 9.09 (1H, d), 8.57 (1H, d),7.56 (1H, d), 6.01 (1H, tt), 5.74 (1H, d), 4.50 (2H, t), 3.56-3.50 (2H,m), 3.55 (3H, s), 1.35 (3H, t).

Present compound A-59: ¹H-NMR (CDCl₃) δ: 9.09 (1H, d), 8.55 (1H, d),7.54 (1H, d), 5.70 (1H, d), 4.53 (2H, t), 4.20 (2H, q), 3.58 (2H, q),1.37 (3H, t), 1.28 (3H, t).

Present compound C-1: ¹H-NMR (CDCl₃) δ: 8.84 (1H, d), 8.34 (1H, d), 7.47(2H, d), 5.57 (1H, d), 4.04 (2H, br), 3.58 (3H, s), 3.42 (2H, br), 1.53(2H, br), 1.29 (3H, t), 1.17 (2H, br).

Present compound C-2: ¹H-NMR (CDCl₃) δ: 8.85 (1H, d), 8.35 (1H, d),7.50-7.46 (2H, m), 5.65 (1H, d), 4.00 (2H, s), 3.57 (3H, s), 3.43 (2H,br), 1.58 (3H, s), 1.54 (3H, s), 1.29 (3H, t).

Present compound C-7: ¹H-NMR (CDCl₃) δ: 8.80 (1H, d), 8.34 (1H, d), 7.50(1H, d), 5.68 (1H, d), 4.02 (2H, s), 3.58 (3H, s), 3.51-3.44 (2H, m),1.55 (3H, s), 1.55 (3H, s), 1.34 (3H, t).

Present compound C-8: ¹H-NMR (CDCl₃) δ: 8.80 (1H, d), 8.34 (1H, d), 7.48(1H, d), 5.59 (1H, d), 4.05 (2H, br), 3.59 (3H, s), 3.51-3.43 (2H, m),1.54 (2H, dd), 1.33 (3H, t), 1.19 (2H, dd).

Present compound A-53: ¹H-NMR (CDCl₃) δ: 7.94 (1H, d), 7.38 (1H, d),6.79 (1H, d), 5.60 (1H, d), 4.47 (2H, t), 3.49 (3H, s), 3.47-3.27 (2H,m), 3.17 (6H, s), 1.26 (3H, t).

Present compound A-50: ¹H-NMR (CDCl₃) δ: 8.42 (1H, d), 7.58 (1H, d),6.91 (1H, d), 5.60 (1H, d), 4.48 (2H, t), 3.52 (3H, s), 3.27-3.25 (2H,m), 3.05 (6H, s), 1.03 (3H, t).

The compounds represented by formula (B-1):

wherein the combination of T, R⁵, A₁, R³ and n represents anycombinations indicated in Table 20.

TABLE 20 Present compound T R⁵ A¹ R³ n B-1 OCH₂CF₂CF₃ Me N H 2 B-2OCH₂CF₂CF₃ Me N CF₃ 2 B-4 OCH₂CF₂CF₃ Et N H 2 B-5 OCH₂CF₂CF₃ Pr N H 2B-6 OCH₂CF₂CF₃ Bu N H 2 B-7 OCH₂CF₂CF₃ Me N Cl 2 B-8 OCH₂CF₂CF₃CH₂CH═CH₂ N H 2 B-9 OCH₂CF₂CF₃ CH₂c-Pr N H 2 B-10 OCH₂CF₂CF₃ i-Pr N H 2B-11 OCH₂CF₂CF₃ Bn N H 2 B-12 OCH₂CF₂CF₃ CH₂CH₂CF₃ N H 2

Present compound B-1: ¹H-NMR (CDCl₃) δ: 8.86 (1H, dd), 8.36 (1H, dd),7.51 (1H, dd), 7.36 (1H, s), 5.88 (1H, s), 4.49 (2H, t), 3.60-3.48 (5H,m), 1.33 (3H, t).

Present compound B-2: ¹H-NMR (CDCl₃) δ: 9.09 (1H, d), 8.57 (1H, d), 7.40(1H, s), 5.89 (1H, s), 4.50 (2H, t), 3.63-3.58 (2H, m) 3.60 (3H, s),1.37 (3H, t).

Present compound B-4: ¹H-NMR (CDCl₃) δ: 8.88 (1H, dd), 8.38 (1H, dd),7.51 (1H, dd), 7.38 (1H, s), 5.87 (1H, s), 4.49 (2H, t), 3.94 (2H, q),3.52-3.42 (2H, m), 1.40 (3H, t), 1.31 (3H, t).

Present compound B-5: ¹H-NMR (CDCl₃) δ: 8.87 (1H, dd), 8.37 (1H, dd),7.51 (1H, dd), 7.36 (1H, s), 5.87 (1H, s), 4.48 (2H, t) 3.91-3.79 (2H,m), 3.54-3.40 (2H, m), 1.83-1.74 (2H, m), 1.31 (3H, t), 0.96 (3H, t).

Present compound B-6: ¹H-NMR (CDCl₃) δ: 8.87 (1H, dd), 8.37 (1H, dd),7.51 (1H, dd), 7.36 (1H, s), 5.87 (1H, s), 4.49 (2H, t), 3.94-3.80 (2H,m), 3.53-3.39 (2H, m), 1.77-1.70 (2H, m), 1.42-1.34 (2H, m), 1.30 (3H,t), 0.95 (3H, t).

Present compound B-7: ¹H-NMR (CDCl₃) δ: 8.80 (1H, d), 8.34 (1H, d), 7.35(1H, s), 5.86 (1H, s), 4.48 (2H, t), 3.57 (3H, s), 3.59-3.52 (2H, m),1.35 (3H, t).

Present compound B-8: ¹H-NMR (CDCl₃) δ: 8.87 (1H, dd), 8.36 (1H, dd),7.51 (1H, dd), 7.36 (1H,), 5.90 (1H, ddt), 5.88 (1H, s), 5.32 (1H, d),5.24 (1H, d), 4.48 (2H, t), 4.48 (2H, d), 3.53-3.44 (2H, m), 1.32 (3H,t).

Present compound B-9: ¹H-NMR (CDCl₃) δ: 8.88 (1H, dd), 8.38 (1H, dd),7.51 (1H, dd), 7.46 (1H, s), 5.88 (1H, s), 4.49 (2H, t), 3.81-3.69 (2H,m), 3.52-3.40 (2H, m), 1.31 (3H, t), 1.26-1.16 (1H, m), 0.69-0.64 (2H,m), 0.39-0.35 (2H, m).

Present compound B-10: ¹H-NMR (CDCl₃) δ: 8.89 (1H, dd), 8.40 (1H, dd),7.52 (1H, dd), 7.51 (1H, s), 5.88 (1H, s), 4.81-4.74 (1H, m), 4.50 (2H,t), 3.43-3.35 (2H, m), 1.45 (6H, d), 1.28 (3H, t).

Present compound B-11: ¹H-NMR (CDCl₃) δ: 8.87 (1H, dd), 8.37 (1H, dd),7.51 (1H, dd), 7.48 (1H, s), 7.39-7.32 (3H, m), 7.25-7.22 (2H, m), 5.89(1H, s), 5.05 (2H, s), 4.42 (2H, t), 3.53-3.41 (2H, m), 1.31 (3H, t).

Present compound B-12: ¹H-NMR (CDCl₃) δ: 8.88 (1H, dd), 8.37 (1H, dd),7.53 (1H, dd), 7.37 (1H, s), 5.89 (1H, s), 4.51 (2H, 4.21-4.06 (2H, m),3.46-3.39 (2H, m), 2.66-2.55 (2H, m), 1.30 (3H, t).

Preparation Example 2

The process was carried out by using the Present compound A-2 place ofthe international compound B-2 according to the method described inReference Preparation Example 2-3 to obtain the present compound A-1shown below.

Present compound A-1: ¹H-NMR (CDCl₃) δ: 8.87 (1H, dd), 8.36 (1H, dd),7.51 (1H, dd), 7.51 (1H, d), 5.69 (1H, d), 4.52 (2H, t), 3.53 (3H, s),3.47-3.41 (2H, m), 1.31 (3H, t).

Preparation Example 2A

The compounds which were prepared according to the method described inPreparation Example 2 and their physical property values are shownbelow.

Present compound A-5: ¹H-NMR (CDCl₃) δ: 8.87 (1H, dd), 8.34 (1H, dd),7.50-7.49 (2H, m), 5.66 (1H, d), 4.51 (2H, t), 4.21-4.18 (2H, m),3.53-3.45 (2H, m), 1.32 (3H, t), 1.27 (3H, t).

Present compound A-34: ¹H-NMR (CDCl₃) δ: 8.89 (1H, dd), 8.36 (1H, dd),7.81 (1H, s), 7.55 (1H, dd), 4.92 (2H, d), 3.51 (3H, s), 3.42 (2H, q),1.33 (3H, t).

Preparation Example 3

To the mixtures of the present compound A-2 0.1 g and chloroform 2 mLwas added mCPBA (purity 70%) 0.06 g under ice-cooling, and the mixtureswere stirred at 0° C. to room temperature for 3 hours. To the mixtureswas added aqueous sodium thiosulfate solution, and the mixtures wereextracted with chloroform. The resulting organic layers were washed withaqueous st dium bicarbonate solution, dried over anhydrous sodiumsulfate, and concentrated under reduced pressure. The resulting residuewas subjected to a silica gel column chromatography (methanol:ethylacetate=1:19) to obtain the present compound A-3 shown below 0.08 g.

Present compound A-3: ¹H-NMR (CDCl₃) δ: 8.73 (1H, dd), 8.35 (1H, dd),7.69 (1H, d, J=8.2 Hz), 7.50 (1H, dd), 5.73 (1H, d), 4.55 (2H, t), 3.54(3H, s), 3.38-3.31 (1H, m), 2.89-2.86 (1H, m), 1.40 (3H, t).

Preparation Example 3A

The compound which was prepared according to the method described inPreparation Example 3 and its physical property value are shown below.

Present compound A-33: ¹H-NMR (CDCl₃) δ: 8.76 (1H, dd), 8.38 (1H, dd),7.97 (1H, s), 7.55 (1H, dd), 4.99-4.91 (2H, m), 3.52 (3H, s), 3.27-3.(1H, m), 2.87-2.83 (1H, m), 1.37 (3H, t).

Preparation Example 4-1

The mixtures of the Present compound A-18 0.1 q, cyclopropyl boronicacid 56 mg, [1,1′-bis(diphenylphosphino)ferrocene]palladium(II)dichloromethane additive 32 mg, tripotassium phosphate 0.23 g, toluene1.5 mL and water 0.4 mL were stirred at 100° C. for 2 hours. Theresulting mixtures were stood to cool to room temperature, and water wasthen added thereto, and the mixtures were extracted with ethyl acetate.The resulting organic layers were dried over anhydrous sodium sulfate,and concentrated under reduced pressure. The resulting residue wassubjected to a silica gel column chromatography (ethylacetate:hexane=3:1) to obtain the present compound A-28 shown below 89mg.

Present compound A-28: ¹H-NMR (CDCl₃) δ: 8.63 (1H, d), 7.94 (1H, d),7.47 (1H, d), 5.67 (1H, d), 4.54-4.48 (2H, m), 3.52 (3H, s), 3.41-3.35(2H, m), 2.06-1.99 (1H, m), 1.29 (3H, t), 1.16-1.13 (2H, m), 0.87-0.82(2H, m).

Preparation Example 4-2

The compounds which were prepared according to the method described inPreparation Example 4-1 and their physical property values are shownbelow.

Present compound A-29: ¹H-NMR (CDCl₃) δ: 9.03 (1H, d), 8.48 (1H, d),7.65-7.61 (2H, m), 7.56 (1H, d), 7.23 (2H, dd), 5.71 (1H, d), 4.53 (2H,t), 3.55 (3H, s), 3.50-3.43 (2H, m), 1.34 (3H, t).

Present compound B-3: ¹H-NMR (CDCl₃) δ: 8.62 (1H, d), 7.94 (1H, d), 7.33(1H, s), 5.89 (1H, s), 4.48 (2H, t), 3.56 (3H, s), 3.48 (2H, q),2.04-2.00 (1H, m), 1.31 (3H, t), 1.16-1.14 (2H, m), 0.86-0.81 (2H, m).

Present compound A-31: ¹H-NMR (CDCl₃) δ: 9.59 (1H, d), 9.02 (1H, dd),8.99 (1H, d), 8.13 (1H, dd), 7.99 (1H, dd), 7.59 (1H, d), 5.72 (1H, d),4.54 (2H, t), 3.56-3.50 (2H, m), 3.55 (3H, s), 1.37 (3H, t).

Preparation Example 4-3

The compounds which were prepared by using the present compound A-47 inlace of the present compound A-18 according to the method described inPreparation Example 4-1 and their physical property values are shownbelow.

Present compound A-44

Present compound A-45: ¹H-NMR (CDCl₃) δ: 8.34 (1H, d), 8.06-8.02 (2H,m), 7.82 (1H, d), 7.53 (1H, d), 7.14 (2H, t), 5.68 (1H, d), 4.51 (2H,t), 3.53 (3H, m), 3.48-3.44 (2H, m), 1.19 (3H, t).

Preparation Example 5-1

The mixtures of the intermediate compound A-23 1.68 g, sodium acetate1.87 g, THF 12 mL and 30% hydrogen peroxide solution 0.4 mL, and water 6mL was stirred at 0° C. for 1 hour. To the resulting ixtures was addedsaturated aqueous sodium thiosulfate solution 3 mL, and the mixtureswere stirred for 1 hour. To the resulting mixtures was added saturatedaqueous ammonium chloride solution at room temperature, and the mixtureswere extracted with chloroform. The resulting organic layers were washedwith saturated brine, dried over sodium sulfate, and concentrated underreduced pressure. The resulting residue was subjected to a silica gelcolumn chromatography (ethyl acetate) to obtain the present und. A-43shown below 0.94 g.

Present compound A-43: ¹H-NMR (CDCl₃) δ: 9.35 (1H, s), 8.10 (1H, d),7.60 (1H, d), 7.55 (1H, d), 5.79 (1H, d), 4.55 (2H, t), 3.62 (3H, s),3.24-3.14 (2H, m), 1.32 (3H, t).

Preparation Example 6

The mixtures of the present compound A-43 0.25 q, 2-iodopyridine 0.17 g,copper(II) iodide 0.02 g, 1-butyl imidazole 0.04 g, potassium carbonate0.16 g, and toluene 3 mL were stirred under reflux for 7 hours. Theresulting mixtures were stood to cool to room temperature, and themixtures were filtered through Celite (Registered Trademark) and thefiltrates were concentrated. The resulting residue was subjected to asilica gel column chromatography (ethyl acetate:hexane 1:2) to obtainthe present compound. A-40 shown below 0.08 g.

Present compound A-40: ¹H-NMR (CDCl₃) δ: 8.75 (1H, d), 8.20 (1H, dd),8.17-8.16 (1H, m), 7.81-7.76 (1H, m), 7.53 (1H, d), 7.10 (1H, dd), 7.07(1H, d), 8.68 (1H, d), 4.52 (2H, t), 3.58-3.36 (2H, m), 3.54 (3H, s),1.33 (3H, t),

Preparation Example 7-1

To the mixtures of the present compound A-43 180 mg, cesium carbonate199 mg, and DMF 1 mL was added iodo ethane 49 μL at under ice-cooling,and the mixtures were stirred at room temperature for 4 hours. Water wasadded to the resulting mixtures, and the precipitated solids werefiltered, and the obtained solids were washed with wate dried underreduced pressure to obtain the present compound A-35 shown below 150 mg.

Present compound A-35: ¹H-NMR (CDCl₃) δ: 8.53 (1H, d), 7.81 (1H, d),7.47 (1H, d), 5.66 (1H, d), 4.50 (2H, t), 4.21-4.15 (2H, m), 3.52 (3H,s), 3.43-3.34 (2H, m), 1.49 (3H, t), 1.30 (3H, t).

Preparation Example 7-2

The compounds which were prepared according to the method described inPreparation Example 7-1 and their physical property values are shownbelow.

Present compound A-36: ¹H-NMR (CDCl₃) δ: 8.53 (1H, d), 7.81 (1H, d),7.47 (1H, d), 5.65 (1H, d), 4.50 (2H, t), 4.09-4.04 (2H, m), 3.52 (3H,),3.43-3.35 (2H, m), 1.92-1.83 (2H, m), 1.31 (3H, t), 1.08 (3H, t).

Present compound A-37: ¹H-NMR (CDCl₃) δ: 8.49 (1H, d), 7.79 (1H, d),7.47 (1H, d), 5.65 (1H, d), 4.72-4.66 (1H, m), 4.50 (2H, t), 3.53 (3H,s), 3.41-3.34 (2H, m), 1.42 (3H, br s), 1.40 (3H, br s), 1.30 (3H, t).

Present compound A-38: ¹H-NMR (CDCl₃) δ: 8.62 (1H, d), 7.90 (1H, d),7.48 (1H, d), 5.68 (1H, d), 4.59 (2H, t), 4.52 (2H, t), 3.53 (3H, s),3.42 (2H, q), 1.32 (3H, t).

Preparation Example 8-1

The mixtures of the interuediate compound A-37 700 mg, and copper powder285 mg, heptafluoropropyl iodide 2.65 g and DMSO 10 mL were stirred at140° C. for 16 hours and a half hour in a sealed container. Theresulting mixtures were cooled to room temperature, and ethyl acetatewas added thereto, and the mixtures were filtered through. Celite(Registered Trademark). The resulting filtrates were extracted withethyl acetate and water. The resulting organic layers were washed withsaturated brine and dried over sodium sulfate, and concentrated underreduced pressure. The resulting residue was subjected to a silica gelcolumn chromatography to obtain the present compound A-12 shown below437 mg.

Present compound A-12: ¹H-NMR (CDCl₃) δ: 8.88 (1H, d), 8.34 (1H, d),7.57-7.50 (2H, m), 6.74 (1H, d), 3.64 (3H, s), 3.46-3.37 (2H, m), 1.29(3H, t).

Preparation Example 8-2

The compound which was prepared according to the method described inPreparation Example 8-1 and its physical property value are shown below

Present compound A-13: ¹H-NMR (CDCl₃) δ: 8.88 (1H, d), 8.34 d),7.57-7.51 (2H, m), 6.77 (1H, d), 3.64 (3H,$), 3.46-3.42 (2H, m), 1.33(3H, t).

Preparation Example 9

The compounds which were prepared by using the intermediate compoundA-37 in place of the present compound A-18 according to the methoddescribed in Preparation

Example 4-1 and their physical property values are shown below.

Present compound. A-14: ¹H-NMR (CDCl₃) δ: 8.89-8.83 (2H, m), 8.36 (1H,d), 7.97 (1H, d), 7.85 (1H, d), 7.55-7.54 (2H, m), 6.30 (1H, d),3.58-3.42 (5H, m) 1.35 (3H, t).

Present compound A-15: ¹H-NMR (CDCl₃) δ: 9.02 (1H, s), 8.90 (2H, 8.36(1H, d), 8.02 (1H, s) 7.54 (2H, d), 6.31 (1H, d), 3.56-3.48 (2H, m),3.42 (3H, s), 1.33 (3H, t).

Present compound A-16: ¹H-NMR (CDCl₃) δ: 8.88 (1H, d), 8.37 (1H, d),7.76 (1H, d), 7.69-7.62 (3H, m), 7.54-7.46 (2H, 6.31 (1H, d), 3.56-3.48(2H, m), 3.42 (3H, s), 1.33 (3H, t).

Preparation Example 10

The process was carried out by using the intermediate compound A-36 inplace of the present compound A-43 and using 2,2,3,3,3-pentafluoropropyltriflate in place of iodo ethane according to the method described inPreparation. Examples 7-1 to obtain the present compound A-30 shownbelow.

Present compound A-30

Preparation Example 11

The process was carried out by using the intermediate compound A-30 inplace of 2-fluoro-4-(trifluoromethyl)phenyl boronic acid and using2-bromo-3-ethylthiopyridine in place of the intermediate compound A-28according Lo the method described in Reference Preparation 12-1 toobtain the present compound A-26 shown below.

Present compound A-26: ¹H-NMR (CDCl₃) δ: 1H-NMR (CDCl₃) δ: 8.46 (1H,dd), 7.81 (1H, s), 7.70 (1H, dd), 7.26 (1H, dd), 4.92 (2H, t), 3.52 (3H,s), 2.90 (2H, q), 1.27 (3H, t).

Preparation Example 12

The mixtures of the intermediate compound A-41 10 g and acetic anhydride50 mL were stirred at 150° C. for 16 hours in a sealed container. Theresulting mixtures were cooled to room temperature, and acetic anhydridezas removed by concentrating under reduced pressure. To the resultingreaction mixtures were added methanol 70 mL and concentratedhydrochloric acid, and the mixtures were stirred at 60° C. for 16 hours.The resulting mixtures were cooled to room temperature, and methanol wasremoved by concentrating under reduced pressure. The resulting reactionmixtures wereextracted with water, saturated aqueous sodium bicarbonatesolution, and ethyl acetate successively, to obtain the presentcompound. A-46 shown below 7 g.

Present compound A-46: ¹H-NMR (CDCl₃) δ: 7.86 (1H, d), 7.63 (1H, d),6.49 (1H, d), 5.68 (1H, d), 4.53 (2H, t), 3.48 (3H, s), 3.25 (2H, q),1.24 (3H, t).

Preparation Example 13

To the mixtures of the present compound A-46 4 g, triethylamine 3.7 mL,and dichloromethane 15 ml was added dropwise trifluoromethane sulfonicanhydride 2.5 mL under ice-cooling, and the mixtures were stirred at 0°C. to room temperature for 16 hours. Water was added to the xtures, andthe mixtures were extracted with dichloromethane. The resulting organiclayers were dried over anhydrous sodium sulfate, and concentrated underreduced pressure to obtain the present compound A-47 4 g.

Present compound A-47: ¹H-NMR (CDCl₃) δ: 8.46 (1H, d), 7.52 (1H, d),7.27 (1H, m), 5.59 (1H, d), 4.51 (2H, t), 3.62 (2H, m), 3.57 (3H, s)1.36 (3H, t).

Preparation Example 14

The mixtures of the present compound A-18 100 mg, tert-butyl carbamate31 mg, 2-dicylohexylphoshino-2′,4′,6′-triisopropyl biphenyl 11 mg,palladium(II) acetate 4 mg, cesium carbonate 99 mg, and dioxane 1.7 mLwas stirred at 100° C. for 3 hours under nitrogen atmosphere. Water wasadded to the resulting mixtures at room temperature, and the mixtureswere extracted with ethyl acetate. The resulting organic lavers werewashed with saturated brine, dried over anhydrous sodium sulfate, andconcentrated under reduced pressure. The resulting residue was subjectedto a silica gel column chromatography (ethyl acetate hexane=1:1) toobtain the present compound A-56 shown below 100 mg.

Present compound A-56: ¹H-NMR (CDCl₃) δ: 8.76 (1H, d), 8.51 (1H, d),7.47 (1H, d), 6.76 (1H, s), 5.65 (1H, d), 4.50 (2H, t), 3.52 (3H, s),3.47-3.41 (2H, m), 1.54 (9H, 1.33 (3H, t).

Preparation Example 14-1

The compounds which were prepared according to the method described inPreparation Example 14 and their physical property values are shownbelow.

Present compound A-57: ¹H-NMR (CDCl₃) δ: 8.83 (1H, d), 8.49 (1H, d),7.49 (1H, d), 6.99 (1H, s), 5.67 (1H, d), 4.51 (2H, t), 3.84 (3H,), 3.53(3H, s), 3.49-3.37 (2H, m), 1.33 (3H, t).

Present compound A-58: ¹H-NMR (CDCl₃) δ: 8.81 (1H, d), 8.50 (1H, d),7.49 (1H, d), 6.97 (1H, s), 5.66 (1H, d), 4.51 (2H, t), 4.28 (2H, q),3.53 (3H, s), 3.50-3.37 (2H, m), 1.34 (3H, t), 1.33 (3H, t).

Present compound A-60: ¹H-NMR (CDCl₃) δ: 8.92 (1H, d), 8.59 (1H, d),8.24 (1H, 7.48 (1H, d), 5.68 (1H, d), 4.51 (2H, t), 3.53 (3H, s),3.48-3.36 (2H, m), 1.63-1.57 (1H, m), 1.32 (3H, t), 1.15-1.11 (2H, m),0.94-0.90 (2H, m).

Preparation Exampl 15

The mixtures of the present compound A-56 1.31 g, trifluoroacetic acid1.8 mL and chloroform 5 mL were stirred at 60° C. for 1 hour. To theresulting mixtures was added 10N aqueous sodium hydroxide solution underice-cooling, and the mixtures were extracted with chloroform Theresulting organic layers were washed with saturated brine, dried overanhydrous sodium sulfate, and concentrated under reduced pressure toobtain the present compound A-62 shown below 1.08 g.

Present compound A-62: ¹H-NMR (CDCl₃) δ: 8.29 (1H, d), 7.60 (1H, d),7.46 (1H, d), 5.63 (1H, d), 4.50 (2H, t), 4.03 (2H, br), 3.53 (3H, s),3.39-3.32 (2H, m), 1.30 (3H, t).

Preparation Example 16

To the mixtues of the present compound A-62 200 mg, cupper(II)bromide152 mg, and acetonitrile 1.1 mL was added dropwise tert-butyl nitrite0.06 mL, and the mixtures were stirred at room temperature for 1 hour.Water was added to the resulting mixtures, and the mixtures wereextracted with ethyl acetate. The resulting organic layers were washedwith saturated brine, dried over anhydrous sodium sulfate, andconcentrated under reduced pressure. The resulting residue was subjectedto a silica gel column chromatography to obtain the present compoundA-61 shown below 139 mg.

Present compound A-61: ¹H-NMR (CDCl₃) δ: 8.90 (1H, d), 8.47 (1H, d),7.51 (1H, d), 5.68 (1H, d), 4.52 (2H, t), 3.53 (3H, s), 3.50-3.44 (2H,m), 1.34 (3H, t).

Preparation Example 17

The mixtures of the present compound. A-18 1.00 g,(trimethylsilyl)acetonitrile 0.7 mL, zinc fluoride 0.27 q,4,5′-bis(diphenylphoshino)-9,9′-dimethylxanthene 0.25 g, andtris(dibenzylideneacetone)dipalladium (0) 0.2 g, and DMF 7 mL werestirred at 140° C. for 3 hours. The resulting mixtures were cooled toroom temperature, and water was added thereto, and the mixtures wereextracted with ethyl acetate. The resulting organic layers were washedwith saturated brine, dried over anhydrous sodium sulfate, andconcentrated under reduced pressure. The resulting residue was subjectedto a silica gel column chromatography (ethyl acetate:hexane=2:1) toobtain the present compound A-48 shown below 0.34 g.

Present compound A-48: ¹H-NMR (CDCl₃) δ: 8.86 (1H, d), 8.33 (1H, d),7.53 (1H, d), 5.70 (1H, d), 4.52 (2H, t), 3.91 (2H, s), 3.53 (3H, s),3.47 (2H, q), 1.34 (3H, t).

Preparation Example 18

The mixtures of the present compound A-48 0.24 g, 1,2-dibromoethane 0.13mL, cesium carbonate 0.50 g, and acetonitrile 4 mL were stirred underreflux for 9 hours. Water was added to the resulting mixtures, and themixtures were extracted with ethyl acetate. The resulting organic layerswere dried over anhydrous sodium sulfate, and concentrated under reducedpressure. The resulting residue was subjected to a silica gel columnchromatography (ethyl acetate) to obtain the present compound A-54 shownbelow 0.13

Present compound A-54: ¹H-NMR (CDCl₃) δ: 8.88 (1H, d), 8.14 (1H, d),7.50 (1H, d), 5.69 (1H, d), 4.52 (2H, t), 3.53 (3H, s), 3.44 (2H, q),1.32 (3H, t), 1.26 (2H, t), 0.88 (2H, t).

Preparation Example 19

The compound which was prepared according to the method described inPreparation Examples 1 to 28 and its physical property value are shownbelow.

The compounds represented by formula (C-1):

wherein the combination of T, R⁵, A¹, R^(3B) and R^(3c) represents anycombinations indicated in Table 21.

TABLE 21 Present compound T R⁵ A³ R^(3b) R^(3c) A-49 OCH₂CF₂CF₃ Me CH HMe A-51 OCH₂CF₂CF₃ Me CH H OEt A-52 OCH₂CF₂CF₃ Me CH H Oi-Pr C-3OCH₂C(Me)₂CN Me CH c-Pr H C-4 OCH₂C(Me)₂CN Me CH 4-F—Ph H C-5OCH₂(1-CN-c-Pr) Me CH c-Pr H C-6 OCH₂(1-CN-c-Pr) Me CH 4-F—Ph H A-65OCH₂CF₂CF₃ Me N CF₃ H A-74 OCH₂CF₂CF₃ CH₂OCH₃ CH H H A-75 OCH₂CF₂CF₃ MeCH CH₃ H A-81 OCH₂CF₂CF₃ Me CBr H H C-9 OCH₂C(Me)₂CN Me CH CF₃ H C-10OCH₂(1-CN-c-Pr) Me CH CF₃ H

Present compound A-49

Present compound A-51: ¹H-NMR (CDCl₃) δ: 8.12 (1H, d), 7.42 (1H, d),6.79 (1H, d), 5.63 (1H, d), 4.48 (2H, t), 4.41-4.35 (2H, m), 3.50 (3H,s), 3.22-3.13 (2H, m), 1.36 (3H, t), 1.31-1.24 (3H, m).

Present compound A-52: ¹H-NMR (CDCl₃) δ: 8.10 (1H, d), 7.41 (1H, d),6.74 (1H, d), 5.63 (1H, d), 5.34-5.30 (1H, m), 4.48 (2H, t), 3.58-3.35(5H, m), 1.38-1.27 (9H, m).

Present compound C-3: ¹H-NMR (CDCl₃) δ: 8.63 (1H, d), 7.94 (1H, d), 7.47(1H, d), 5.64 (1H, d), 4.00 (2H, s), 3.58 (3H, s), 3.43-3.34 (2H, m),2.05-1.99 (1H, m), 1.55 (3H, s), 1.55 (3H, s), 1.29 (3H, t), 1.15-1.13(2H, m), 0.87-0.82 (2H, m).

Present compound C-4: ¹H-NMR (CDCl₃) δ: 9.03 (1H, d), 8.48 (1H, d),7.65-7.61 (2H, m), 7.56 (1H, d), 7.25-7.20 (2H, m), 5.69 (1H, d), 4.03(2H, s), 3.60 (3H, s), 3.51-3.43 (2H, m), 1.56 (3H, s), 1.56 (3H, s),1.34 (3H, t).

Present compound C-5: ¹H-NMR (CDCl₃) δ: 8.63 (1H, d), 7.94 (1H, d), 7.45(1H, d), 5.56 (1H, d), 4.04 (2H, d), 3.58 (3H, s), 3.42-3.33 (2H, m),2.03-2.00 (1H, m) 1.53 (2H, dd), 1.29 (3H, t), 1.18 (2H, dd), 1.15-1.12(2H, m), 0.87-0.82 (2H, m).

Present compound C-6: ¹H-NMR (CDCl₃) δ: 9.02 (1H, d), 8.48 (1H, d), 7.63(2H, dd), 7.54 (1H, d), 7.22 (2H, t), 5.61 (1H, d), 4.07 (2H, br), 3.61(3H, s), 3.50-3.43 (2H, m), 1.55 (2H, dd), 1.34 (3H, t), 1.19 (2H, dd).

Present compound A-65: ¹H-NMR (CDCl₃) δ: 9.13-9.11 (1H, dd), 8.58-8.56(1H, dd), 7.86 (1H, s), 4.93-4.90 (2H, 3.54-3.48 (2H, m), 3.52 (3H, s),1.37 (3H, t).

Present compound A-74: ¹H-NMR (CDCl₃) δ: 8.87 (1H, dd), 8.34 (1H, dd),7.53-7.49 (2H, m), 5.68 (1H, d), 5.57-5.53 (2H, m), 4.53 (2H, t),3.50-3.44 (5H, m), 1.32 (3H, t).

Present compound A-75: ¹H-NMR (CDCl₃) δ: 8.68 (1H, d), 8.16 (1H, d),7.49 (1H, d), 5.67 (1H, d), 4.51 (2H, t), 3.52 (3H, s), 3.43-3.39 (2H,m), 2.48 (3H, s), 1.31 (3H, t).

Present compound A-81: ¹H-NMR (CDCl₃) δ: 8.87 (1H, dd), 8.34 (1H, dd),7.61 (1H, s), 7.55 (1H, dd), 4.76-4.71 (2H, m), 3.60 (3H, s), 3.53-3.48(2H, m), 1.35 (3H, t).

Present compound C-9: ¹H-NMR (CDCl₃) δ: 9.09 (1H, d), 8.57 (1H, d), 7.56(1H, d), 5.70 (1H, d), 4.03 (2H, s), 3.60 (3H, s), 3.54 (2H, q), 1.56(3H, s), 1.55 (3H, s), 1.36 (3H, t).

Present compound C-10: ¹H-NMR (CDCl₃) δ: 9.08 (1H, d), 8.57 (1H, d),7.53 (1H, d), 5.62 (1H, d), 4.07 (2H, br), 3.61 (3H, s), 3.53 (2H, q),1.56-1.54 (2H, m), 1.35 (3H, t), 1.21-1.17 (2H, m).

The compounds represented by formula (D-1)

wherein the combination of T, R⁵, A¹, A², A⁴, R^(3a), R^(3b) and R^(3c)represents any combinations indicated in Table 22.

TABLE 22 Present compound T R⁵ A¹ A² A⁴ R^(3a) R^(3b) R^(3c) B-13OCH₂CF₂CF₃ Me N CH CH H OEt H B-14 OCH₂CF₂CF₃ Me N CH CH H OH H B-17OCH₂CF₂CF₃ Me N N CH H H H

Present compound B-13: ¹H-NMR (CDCl₃) δ: 8.52 (1H, 7.81 (1H, d), 7.32(1H, s), 5.86 (1H, s), 4.47 (2H, t), 4.21-4.14 (2H, m), 3.55 (3H, s),3.52-3.45 (2H, m), 1.48 (3H, t), 1.32 (3H, t).

Present compound B-14: ¹H-NMR (CDCl₃) δ: 8.08 (1H, d), 7.59 (1H, d),7.44 (1H, s), 6.08 (1H, s), 4.55 (2H, t), 3.62 (3H, s), 3.31-3.20 (2H,m), 1.34 (3H, t).

Present compound B-17: ¹H-NMR (CDCl₃) δ: 8.94 (1H, dd), 8.33 (1H, dd),7.61 (1H, dd), 6.04 (1H, s), 4.54 (2H, t), 3.83 (3H, s), 3.49 (2H, q),1.36 (3H, t).

Present compound B-15: ¹H-NMR (CDCl₃) δ: 8.54 (1H, dd), 7.79 (1H, dd),7.32 (1H, dd), 6.07 (lH, s), 4.53 (2H, t), 3.84 (3H, s), 2.91 (2H, q),1.26 (3H, t).

Present compound B-16: ¹H-NMR (CDCl₃) δ: 8.64 (1H, dd), 8.42 (1H, dd),7.61 (1H, dd), 6.13 (1H, s), 4.57 (2H, t), 3.87 (3H, s), 3.29-3.21 (1H,m), 2.91-2.87 (1H, m), 1.37 (3H, t).

Reference Process Example 18

A mixture of the intermediate compound A-19 8 g and DMF 50 mL was cooledto 0° C., and thereto was added sodium hydride (60%, in oil) 2.8 g. Theresulting mixture was stirred at 0° C. for 30 minutes, and thereto wasadded the compound of formula (D):

9 g, and the mixture was stirred at 0° C. for 3 hours. Water was addedto the resulting mixture, and the mixture was extracted with ethylacetate. The resulting organic layer was dried over anhydrous sodiumsulfate, and Concentrated under reduced pressure. The resulting residuewas subjected to a silica gel colUmn chromatography to obtain theintermediate compound A-43 shown below 0.5 g and the intermediatecompound A-46 shown below 0.4 g.

Intermediate compound A-43: ¹H-NMR (CDCl₃) δ: 8.01 (1H, d), 7.50 (1H,d), 6.98 (1H, d), 6.53 (1H, d), 3.89 (3H, s), 3.13 (6H, s), 2.96-2.86(2H, m), 1.16 (3H, t).

Intermediate compound A-46: ¹H-NMR (CDCl₃) δ: 8.47 (1H, d), 7.69 (1H,d), 7.00-6.98 (2H, m), 3.95 (3H, s), 3.21-3.13 (2H, m), 3.05 (6H, s),0.99 (3H, t).

Preparation Example 20

To a mixture of the present compound A-18 2.50 g,4,5-bis(diphenylphosphino)-9,9-dimethylxantene 629 mg, palladium (II)acetate 122 mg, N,N-diisopropylethylamine 2.8 mL, and toluene 19 mL wereadded dropwise mixture of 2,4,6-trichlorophenyl formate 3.67 g andtoluene 17 mL over 6 hours at 100° C. under nitrogen atmosphere. Theresulting mixture was stirred at 100° C. for 2 hours, and the mixturewas then cooled to room temperature. Water was added to the resultingmixture and the mixture was extracted with ethyl acetate. The resultingorganic layer was washed with saturatedbrine, dried over anhydroussodium sulfate, and concentrated under reduced pressure. The resultingresidue was subjected to a silica gel column chromatography (ethylacetate:hexane=1:1) to obtain the present compound A-63 shown below 1.61g.

Present compound A-63: ¹H-NMR (CDCl₃) δ: 9.58 (1H, d), 9.07 (1H, d),7.62 (1H, d), 7.47 (2H, s), 5.74 (1H, d), 4.54 (2H, t), 3.62-3.55 (2H,m), 3.55 (3H, s), 1.40 (3H, t).

Preparation Example 21

To a mixture of the present compound A-63 1.31 g, THF 11 mL and water5.5 mL was added lithium hydroxide monohydrate 169 mg under ice-cooling,and the mixture was stirred at room temperature for 30 minutes. Waterwas added to the resulting mixture, and the mixture was extracted withethyl acetate. The resulting aqueous layer was acidified with 6Nhydrochloric acid, and the mixture was extracted with ethyl acetate. Theresulting organic layer was dried over anhydrous sodium sulfate,concentrated under reduced pressure to obtain the present compound A-64shown below 0.5 g

Present compound A-64: ¹H-NMR (CDCl₃) δ: 9.28 (1H, d), 8.83 (1H, d),7.66 (1H, d), 5.83 (1H, d), 4.57 (2H, t), 3.61 (3H, s), 3.53-3.45 (2H,m), 1.41 (3H, t).

Preparation Example 22

To a mixture of the present compound A-64 126 mg, chloroform 2 mL andDMF 16 μL was added oxalyl chloride 46 μL under ice-cooling, and themixture was stirred at room temperature for 1 hour. Methanol 0.5 mL wasadded to the resulting mixture under ice-cooling, and the mixture wasstirred at room temperature for 2 hours. Aqueous saturated hydrogencarbonate solution was added to the resulting mixture, and the mixturewas extracted with ethyl acetate. The resulting organic layer was driedover anhydrous sodium sulfate, concentrated under reduced pressure toobtain the present compound A-66 shown below 0.12 g.

Present comp A-66: ¹H-NMR (CDCl₃) δ: 9.40 (1H, d), 8.89 (1H, d), 7.57(1H, d), 5.71 (1H, d), 4.52 (2H, t), 4.01 (3H, s), 3.56-3.52 (2H, m),3.5 (3H, s), 1.36 (3H, t).

Preparation Example 22-1

The compound which was prepared according to the method described inPreparation Example 22 and its physical property value are shown below.

Present compound A-67: 1H-NMR (CDCl₃) δ: 9.40 (1H, d), 8.88 (1H, d),7.56 (1H, d), 5.71 (1H, d), 4.53 (2H, t), 4.47 (2H, q), 3.54 (2H, q),3.53 (3H, s), 1.44 (3H, t), 1.36 (3H, t).

Present compound A-68: ¹H-NMR (CDCl₃) δ: 9.38 (2H, d), 8.86 (1H, d),7.55 (1H, d), 5.71 (1H, d), 5.37-5.31 (1H, m), 4.53 (2H, t), 3.54-3.52(5H, m), 1.42 (6H, d), 1.36 (3H, t).

Present compound A-71: ¹H-NMR (CDCl₃) δ: 9.22 (1H, d), 8.64 (1H, d),7.54 (1H, d), 6.27 (1H, br), 5.70 (1H, d), 4.52 (2H, t), 3.53 (3H, s),3.50 (2H, q), 3.08 (3H, d), 1.34 (3H, t).

Present compound A-70: ¹H-NMR (CDCl₃) δ: 9.26 (1H, d), 8.71 (1H, d),7.55 (1H, d), 6.31 (1H, br), 5.84 (1H, br), 5.71 (1H, d), 4.53 (2H, t),3.51 (2H, q), 3.54 (3H, s), 1.34 (3H, t).

Present compound A-72: ¹H-NMR (CDCl₃) δ: 8.93 (1H, d), 8.39 (1H, d),7.53 (1H, d), 5.69 (1H, d), 4.52 (2H, t), 3.54-3.45 (2H, m), 3.54 (3H,s), 3.17 (3H, s), 3.08 (3H, s), 1.33 (3H, t).

Present compound A-73: ¹H-NMR (CDCl₃) δ: 9.20 (1H, d), 8.58 (1H, d),7.53 (1H, d), 6.41 (1H, br), 5.70 (1H, d), 4.52 (2H, t), 3.53-3.46 (2H,m), 3.53 (3H, s), 2.98-2.92 (1H, m), 1.33 (3H, t), 0.96-0.91 (2H, m),0.71-0.67 (2H, m).

Preparation Example 23

A mixture of the present compound A-61 200 mg, sodium iodide 178 mg,copper (i) iodide 15 mg, trans-N,N′-dimethylcyclohexane-1,2-diamine 22mg, and dioxane 13 was stirred at 130° C. for 2 hours. Water was addedto the resulting mixture at room temperature, and the mixture wasextracted with ethyl acetate. The resulting organic layer was washedwith saturated brine, dried over anhydrous sodium sulfate, andconcentrated under reduced pressure. The resulting residue was subjectedto a silica gel column chromatography to obtain the present compoundA-69 shown below 160 mg.

Present compound A-69: ¹H-NMR (CDCl₃) δ: 9.04 (1H, d), 8.63 (1H, d),7.51 (1H, d), 5.68 (1H, d), 4.51 (2H, t), 3.52 (3H, s), 3.46 (2H, q),1.33 (3H, t).

Preparation Example 24

To a mixture of the present compound A-61 0.5 g, tert-butyl carbazate0.2 g,2-(dicyclohexylphoshino)-3.6-dimethoxy-2′,4′,6′-triisopropyl-1,1′-biphenyl54 mg, cesium carbonate 0.97 g, and dioxane 6.6 mL was addedtris(dibenzylideneacetone)dipalladium (0) 90 mg, and the mixture wasstirred at 100° C. for 1.5 hours. Water was added to the resultingmixture at room temperature, and the mixture was extracted with ethylacetate. The resulting organic layer was washed with saturated brine,dried over anhydrous sodium sulfate, and concentrated under reducedpressure. The resulting residue was subjected to a silica gel columnchromatography (ethyl acetate:hexane=1:1) to obtain the present compoundA-76 shown below 0.21 g.

Present compound A-76: ¹H-NMR (CDCl₃) δ: 9.14 (1H, d), 8.58 (1H, d),7.50 (1H, d), 5.66 (1H, d), 4.50 (2H, t), 4.45 (2H, s), 3.52 (3H, s),3.45 (2H, q), 1.57 (9H, s), 1.33 (3H, t).

Preparation Example 25

A mixture of the present compound A-76 0.27 g, trifluoro cetic acid 0.18mL, and chloroform 1.5 mL was stirred at 60° C. for 5 hours. Theresulting mixture was cooled to room temper ure, and concentrated underreduced pressure to obtain the present compound A-77 as crude productshown below.

Present compound A-77: ¹H-NMR (CDCl₃) δ: 8.45 (1H, d), 7.92 (1H, d),7.59 (1H, d), 5.84 (1H, d), 5.39 (2H, br), 4.57 (2H, t), 3.56 (3H, s),3.25 (2H, q), 1.27 (3H, t).

Preparation Example 26

To the present compound A-77 were added ammonium formate 0.15 g andethyl orthoformate 1 mL, and the mixture was stirred under reflux for 6hours. Water was added to the resulting mixture at room temperature, andthe mixture was extracted with ethyl acetate. The resulting organiclayer was washed with saturated brine, dried over anhydrous sodiumsulfate, and concentrated under reduced pressure. The resulting residuewas subjected to a silica gel column chromatography (ethyl acetate) toobtain the present compound A-78 shown below 35 mg and the presentcompound A-79 shown below 0.13 g.

Present compound A-78: ¹H-NMR (CDCl₃) δ: 9.26 (1H, d), 8.78 (1H, s),8.68 (1H, d), 7.59 (1H, d), 5.73 (1H, d), 4.55 (2H, t), 3.60-3. (5H, m),1.38 (3H, t).

Present compound A-79: ¹H-NMR (CDCl₃) δ: 9.26 (1H, d), 8.74 (1H, s),8.57 (1H, d), 8.22 (1H, s), 7.57 (1H, d), 5.73 (1H, d), 4.54 (2H, t),3.58-3.50 (5H, m), 1.37 (3H, t).

Preparation Example 27

A mixture of the present compound A-2 1.0 g, N-bromosuccinimide 0.45 g,and DMF 10 mL was stirred for 2 hours at room temperature. Aqueoussaturated hydrogen carbonate solution was added to the resultingmixture, and the mixture was extracted with ethyl acetate. The resultingorganic layer was washed with saturated brine, dried over anhydroussodium sulfate, and concentrated. The resulting residue was subjected toa silica gel column chromatography (methanol:chloroform=1:9) to obtainthe present compound A-80 shown below 0.74 g.

Present compound A-80: ¹H-NMR (CDCl₃) δ: 8.44 (1H, dd), 7.71 (1H, dd),7.63 (1H, s), 7.26 (1H, dd), 4.70 (2H, t), 3.62 (3H, s), 2.90 (2H, q),1.27 (3H, t).

Preparation Example 28

A mixture of the present compound A-2 1.5 g, N-bromosuccinimide 1.02 g,tert-butoxide potassium 0.55 g, and cyanamide 0.21 g, and methanol 30 mLwas stirred at room temperature for 5 hours. Water was added to theresulting mixture, and the mixture was extracted with ethyl acetate. Theresulting organic layer was concentrated under reduced pressure toobtain the present compound A-83 shown below 0.93 g.

Present compound A-83: ¹H-NMR (CDCl₃) δ: 8.80 (1H, dd), 8.46 (1H, dd),7.97 (1H, d), 7.52 (1H, dd), 5.86 (1H, d), 4.60 (2H, t), 3.77-3.69 (1H,m), 3.57 (3H, s), 3.44-3.39 (1H, m), 1.61 (3H, t).

Preparation Example 29

Examples of the compounds that can be prepared according to the methodsdescribed in the Preparation Examples 1 to 28 are indicated below.

The compounds represented by formula (E-1):

wherein the combination of T, A², A³, Q⁵, Q⁶, R^(3b) and R^(3c)represents any combinations indicated in Table 23.

TABLE 23 Present compound T A² A³ Q⁵ Q⁶ R^(3b) R^(3c) A-82 OCH₂CF₂CF₃ CHCMe O O H H A-84 OCH₂CF₂CF₃ CH CH O N—CN H H A-85 OCH₂CF₂CF₃ CH CH O NHH H A-86 OCH₂CF₂CF₃ CH CH O NMe H H A-87 OCH₂CF₂CF₃ N CH — — H H A-88OCH₂CF₂CF₃ N CH O — H H A-89 OCH₂CF₂CF₃ N CH O O H H A-90 OCH₂CF₂CHF₂ NCH O O H H A-91 OCH₂CF₂CF₃ N CH O O CF₃ H A-92 OCH₂CF₂CF₃ N CH O O c-PrH A-93 OCH₂CF₂CF₃ N CH O O 4-F—Ph H A-94 OCH₂CF₂CF₃ N CH O O OEt H A-95OCH₂CF₂CF₃ N CH O O H CF₃ A-96 OCH₂CF₂CF₃ N CH O O H c-Pr A-97OCH₂CF₂CF₃ N CH O O H 4-F—Ph A-98 OCH₂CF₂CF₃ N CH O O H OEt

The compounds represented by formula (F-1):

wherein the combination of T, A², A⁴, Q⁵, Q⁶, R^(3b) and R^(3c)represents any combinations indicated in Table 24.

TABLE 24 Present compound T A² A⁴ Q⁵ Q⁶ R^(3b) R^(3c) B-18 OCH₂CF₂CF₃ CHN — — H H B-19 OCH₂CF₂CF₃ CH N O — H H B-20 OCH₂CF₂CF₃ CH N O O H H B-21OCH₂CF₂CF₃ CH N O O CF₃ H B-22 OCH₂CF₂CHF₂ CH N O O c-Pr H B-23OCH₂CF₂CF₃ CH N O O 4-F—Ph H B-24 OCH₂CF₂CF₃ CH N O O OEt H B-25OCH₂CF₂CF₃ N CH O O CF₃ H B-26 OCH₂CF₂CF₃ N CH O O OEt H B-27OCH₂CF₂CHF₂ N CH O O H 4-F—Ph B-28 OCH₂CF₂CF₃ N CH O O H c-Pr

Next, the formulation Examples of the Present compound Z is described.The “parts” represents “part by weight” unless otherwise specified.

Formulation Example 1

Into a mixture of 35 parts of xylene and 35 parts of DMF, ten parts ofany one of the Present compounds A-1 to A-98, B-1 to B-28, and C-1 toC-10 is added, followed by mixing, and then 14 parts of polyoxyethylenestyryl phenyl ether and parts of calcium dodecylbenzene sulfonate areadded, followed by mixing them to obtain each formulation.

Formulation Example 2

Four (4) parts of sodium lauryi sulfate, 2 parts of calcium ligninsulfonate, 20 parts of synthetic hydrated silicon oxide fine powder and54 parts of diatomaceous earth are mixed, and further 20 parts of anyone of the Present compounds A-1 to A-98, B-1 to B-28, and C-1 to C-10is added, followed by mixing them to obtain each formulation.

Formulation Example 3

To 2 parts of any one of the Present compounds A-1 to A-98, B-1 to B-28,and C-1 to 0-10, 1 part of synthetic hydrated silicon oxide fine powder,2 parts of calcium lignin sulfonate, 30 parts of bentonite and 65 partsof kaolin clay are added, followed by mixing. Then the mixtures arestirred, granulated with a granulator, and forced-air dried to obtaineach formulation.

Formulation Example 4

Into an appropriate amount of acetone, 1 part of any one of the Presentcompoulds A-1 to A-98, B-1 to B-28, and C-1 to C-10 is added, followedby mixing, and then 5 parts of hydrous silica, 0.3 parts of isopropylacid phosphate and 93.7 parts of kaolin clay are added, followed bymixing 2) with stirring thoroughly and removal of acetone from themixtures by evaporation to obtain each formulation.

Formulation Example 5

Thirty five (35) parts of a mixture of polyoxyethylene alkyl ethersulfate ammonium salt and hydrous silica (weight ratio of 1:1), 20 partsof any one of the Present compounds A-1 to A-98, B-1 to B-28, and C-1 toC-10, and 45 parts of water are mixed thoroughly to obtain eachformulation.

Formulation Example 6

Into a mixture of 5 parts of xylene and 5 parts of trichloroethane, 0.1parts of any one of the Present compounds A-1 to A-98, B-1 to B-28, andC-1 to C-10 is added, followed by mixing, and the resulting mixture isthen mixed with 89.9 parts of kerosene to obtain each formulation.

Formulation Example 7

Into 0.5 mL of acetone, 10 mg of any one of the Present compounds A-1 toA-98, B-1 to B-28, and C-1 to C-10 is added, followed by mixing, and thesolution is added dropwise to 5 g of a solid feed powder for an animal(solid feed powder for rearing and breeding CE-2, manufactured by CLEAJapan, Inc.), followed by mixing the resulting mixture uniformly, andthen by drying them by evaporation of acetone to obtain each poisonbait.

Formulation Example A

Into an aerosol can, 0.1 part of any one of the Present compounds A-1 toA-98, B-1 to B-28, and C-1 to C-10, and 49.9 parts of Neothiozole (ChuoKasei Co., Ltd.) are placed. After mounting an aerosol valve, 25 partsof dimethyl ether and 25 parts of LPG are filled, followed by shakingand further mounting an actuator to obtain each oily aerosol.

Formulation Example 9

A mixture of 0.6 part of any one of the Present compounds A-1 to A-98,B-1 to B-28, and C-1 to C-10, 0.01 part of BHT(2,6-di-vert-butyl-4-methylphenol), 5 parts of xylene, 3.39 parts ofdeodorized kerosine and 1 part of an emulsifier {Rheodol MO-60(registered trademark of Kao Corporation)} and 50 parts of distilledwater are filled into an aerosol container, and a valve part isattached. Then, 40 parts of a propellant (LPG) is filled therein throughthe valve under pressure to obtain each aqueous aerosol.

Formulation Example 10

0.1 parts of any one of the Present compounds A-1 to A-98, B-1 to B-28,and C-1 to C-10 are mixed into 2 mL of propylene glycol, and theresulting solution is impregnated into a ceramic plate having a size of4.0 cm×4.0 cm and a thickness of 1.2 cm, to obtain each thermalfumigant.

Preparation Example 11

5 parts of any one of the Present compounds A-1 to A-98, B-1 to B-28,and C-1 to C-10, and 95 parts of ethylene-methyl methacrylate copolymer(the ratio of the methyl methacrylate in the copolymer: 10 weight %),Acryft (registered by trademark) WD 301, manufactured by SumitomoChemical Co. Ltd.) are melted and kneaded with a closed type pressurekneader (manufactured by Moriyama Manufacturing Co. Ltd.), and theresulting kneaded product is extruded from an extrusion molding machinethrough a molding die to obtain each rod-shaped molded product having alength of 15 cm and a diameter of 3 mm.

Formulation Example 12

5 parts of any one of the Present compounds A-1 wo A-98, B-1 to B-28,and C-1 to C-10, and 95 parts of plasticized polyvinyl chloride resinare melted and kneaded with a closed type pressure kneader (manufacturedby Moriyama Manufacturing Co. Ltd.), and the resulting kneaded productis extruded from an extrusion molding machine through a molding die toobtain each rod-shaped molded product having a length of 15 cm and adiameter of 3 mm.

Formulation Example 13

One hundred (100) mg of any one of the Present compounds A-1 to A-98,B-1 to B-28, and C-1 to C-10, 68.75 mg of lactose, 237.5 mg of cornstarch, 43.75 mg of microcrystalline cellulose, 18.75 mg ofpolyvinylpyrrolidone, 28.75 mg of sodium carbomethyl starch and 2.5 mgof magnesium stearate are mixed, and the resulting mixture wascompressed to an appropriate size to obtain each tablet.

Formulation Example 14

Twenty five (25) mg of any one of the Present compounds A-1 to A-98, B-1to B-28, and C-1 to C-10, 60 mg of lactose, 25 mg of corn starch, 6 mgof carmellose calcium and an appropriate amount of 5% of hydroxypropylmethylcellulose are mixed, and the resulting mixture are filled into ahard shell gelatin capsule or a hydroxypropyl methylcellulose capsule toobtain each capsule.

Formulation Example 15

To 100 mg of any one of the Present compounds A-1 to A-98, B-1 to B-28,and C-1 to C-10, 500 mg of fumaric acid, 2,000 mg of sodium chloride,150 mg of methyl paraben, 50 mg of propyl paraben, 25,000 mg ofgranulated sugar, 13,000 mg of sorhitol (70% solution), 100 mg of VeegumK (manufactured by Vanderbilt, 35 mg of perfume and 500 mg of coloringagent, a distilled water is added so that a final volume is set to be100 mL, followed by mixing them to obtain each suspension for oraladministration.

Formulation Example 16

Into a mixture of 5% by weight of an emulsifier, 3% by weight of benzylalcohol and 30% by ht of propylene glycol, 5% by weight of any one ofthe Present compounds A-1 to A-98, B-1 to B-28, and C-1 to C-10 isdissolved, and phosphate buffer is added thereto so that a pH of thesolution is set to be 6.0 to 6.5, and water is added as the rest partsto obtain each solution for oral administration.

Formulation Example 17

To a mixture of 57% by weight of fractional di tillated palm oil and 3%by weight of polysorbate 85, 5% by weight of aluminum distearate isadded, and heated to disperse it. The resulting mixture is cooled toroom temperature, and 25% by weight of saccharin is dispersed in an oilvehicle. Ten (10) % by weight of any one of the Present compounds A-1 toA-98, to B-28, and C-1 to C-10 is divided thereto to obtain each pastefor oral administration.

Formulation Example 18

Five (5) % by weight of any one of the Present compounds A-1 to A-98,B-1 to B-28, and C-1 to C-10 is mixed with 95% by weight of limestonefiller, followed by a wet granulation of the resulting mixture to obtaineach granule for oral administration.

Formulation Example 19

Into 80 parts of diethylene glycol monomethyl ether, 5 parts of any oneof the Present compounds A-1 to A-98, B-1 to B-28, and C-1 to C-10 isdissolved, and 15 parts of propylene carbonate is added thereto, and theresulting mixture is mixed to obtain each spot-on solution.

Formulation Example 20

Into 70 parts of diethylene glycol monomethyl ether, 10 parts of any oneof the Present compounds A-1 to A-98, B-1 to B-28, and C-1 to C-10 isdissolved, and 20 parts of 2-octyldodecanol is added thereto, and theresulting mixture is mixed to obtain a pour-on solution.

Formulation Example 21

To 0.5 parts of any one of the Present compounds A-2 to A-98, B-1 toB-28, and C-1 to C-10, 60 parts of Nikkol (registered by trademark)TEALS-42 (manufactured by Nikko Chemical Co. Ltd.: 42% of aqueoussolution of lauryl sulfuric acid triethanol amine) and 20 parts ofpropylene glycol are added, and the resulting mixture is mixed withstirring thoroughly, and 19.5 parts of water is then added thereto andthe resulting mixture is further mixed with stirring thoroughly toobtain each hydrogenous solution of shampoo formulation.

Formulation Example 22

Zero point one five (0.15)% by weight of any one of the Presentcompounds A-1 to A-98, B-1 to B-28, and C-1 to C-10, 95% by weight ofanimal feed, as well as 4.85% by weight of a mixture of dibasic calciumphosphate, diatomaceous earth, aerosol and carbonate (or chalk) aremixed with stirring thoroughly to obtain each premix for animal feed.

Formulation Example 23

Seven point two (7.2) g of any one of the Present compounds A-1 to A-96,B-1 to B-28, and C-1 to C-10, and 92.8 g of Hosco (registered trademark)S-55 (manufactured by Maruishi Pharmaceuticals) are melted and mixed at100° C., and the resulting mixture was poured into a suppository mold,followed by perforling a cooling solidification to obtain eachsuppository.

Next, Test Examples are used to show an efficacy of the Present compoundZ on controlling harmful arthropods.

The following test examples were carried out at 25° C.

Test Example 1

The test compounds is made to a formulation according to a similarmethod to that described in the Formulation Example 5, and thereto isadded water containing 0.03 v/v % of spreader to prepare a dilutedsolution containing a prescribed concentration of the test compound.

Cucumber (Cucurnis sativus) seedling (on the developmental stage of thesecond true leaf) is planted in a container and approximately 30 cottonaphids (Aphis ossypii) (all stages of life) are released onto the leavesof the cucumber. After 1 day, the diluted solutions are sprayed into theseedling in a ratio of 10 mL/seedling. Further, after 5 days, the numberof the surviving insects is examined and the controlling value iscalculated by the following equation.Controlling value (%)={1−(Cb×Tai)/(Cai×Tb)}×100wherein the symbols in the formula represent the following descriptions.

Cb: Number of the test insects in untreated group;

Cai: Number of thesurviving insects at the time of the investigation inuntreated group;

Tb: Number of the test insects in treated group;

Tai: Number of the surviving insects at the time of the investigation intreated group;

Here the “untreated group” represents a group where the similartreatment procedure to that of the treated group except not using thetest compound is done.

The test was conducted by making the prescribed concentration 500 ppmand using the below-mentioned Present compounds as a test compoundaccording to the test example 1. As a result of the test, thebelow-mentioned Present compounds showed 90% or greater as thecontrolling value.

Present compound number: Present compounds A-1, A-3, A-6, A-7, A-8, A-9,A-10, A-11, A-12, A-13, A-14, A-15, A-16, A-17, A-18, A-19, A-21, A-23,A-24, A-25, A-26, A-30, A-31, A-33, A-34, A-35, A-36, A-37, A-38, A-39,A-41, A-48, A-53, A-74, A-75, A-80, A80, A-81, A-82, A-83, B-3, B-8,B-9, B-11, B-13, B-17, C-1 and C-2.

The test was conducted by making the prescribed concentration 200 ppmand using the below-mentioned Present compounds as a test compoundaccording to the test example 1. As a result of the test, thebelow-mentioned Present compounds showed 90% or greater as thecontrolling value.

Present compound number: Present compounds A-1, A-2, A-3, A-6, A-7, A-8,A-10, A-11, A-12, A-14, A-15, A-16, A-18, A-19, A-20, A-23, A-24, A-26,A-28, A-29, A-31, A-33, A-34, A-35, A-35, A-37, A-38, A-39, A-40, A-48,A-53, A-54, A-55, A-56, A-57, A-58, A-59, A-60, A-61, A-62, A-66, A-67,A-68, A-69, A-70, A-71, A-72, A-73, A-75, A-79, B-2, 13-3, B-4, B-5,B-6, B-8, B-13, B-15, C-1, C-2, C-3, C-4, C-5, and C-6.

Test Example 2

The test compounds are made to a formulation according to a similarmethod to that described in the Formulation Example 5, and thereto isadded water to prepare a diluted solution containing a prescribedconcentration of the test compound.

Cucumber seedling (on the developmental stage of the second true leaf)is planted in a container, and the diluted solutions are the ratio on 5mL/seedling are irrigated into the plant foot. After 7 days,approximately 30 cotton aphids (all stages of life) are inoculated ontothe cucumber leaves. Further, after additional 6 days, the number of thesurviving insects is examined, and the controlling value is calculatedby the following equation.Controlling value (%)={1−(Cb×Tai)/(Cai×Tb)}×100wherein the symbols in the formula represent the following descriptions.

Cb: Number of the test insects in untreated group;

Cai: Number of the surviving insects at the time of the investigation inuntreated group;

Tb: Number of the test insects in treated group;

Tai: Number of the surviving insects at the time of the investigation intreated group;

Here the “untreated group” represents a group where the sirrilartreatment procedure to that of the treated group except not using thetest compound is done.

The test was conducted by making the prescribed concentration 1,000 ppmand using the below-mentioned Present compounds as a test compoundaccording to the test example 2. As a result of the test, thebelow-mentioned. Present compounds showed 90% or greater as thecontrolling value.

Present compound number: Present compounds A-1, A-2, A-3, A-6, A-7, A-8,A-10, A-11, A-14, A-16, A-17, A-18, A-23, A-24, A-26, A-28, A-29, A-31,A-33, A-34, A-35, A-36, A-37, A-38, A-39, A-40, A-48, A-53, A-54, A-55,A-56, A-57, A-58, A-59, A-60, A-61, A-62, A-67, A-68, A-69, A-70, A-71,A-72, A-73, A-75, A-79, B-2, B-3, B-4, B-13, C-1, C-2, C-3, and C-5.

Test Example 3

The test compounds are made to a formulation according to a similarmethod to that described in the Formulation Example 5, and thereto isadded water containing 0.03 v/v % of a spreader to prepare a dilutedsolution containing a prescribed concentration of the test compound.

Rice (Oryza sativa) seedling (on the developmental age of the secondtrue leaf) is planted in a container, and the diluted solutions aresprayed into the seedling in a ratio of 10 mL/seedling. Thereafter, 203rd instar larvae of brown planthoppers (Nilaparvata lugens) arereleased onto the rice leaves. After 6 days, the morality is calculatedby the following equation.Morality (%)={1−the number of the surviving insects/20}×100

The test was conducted by making the prescribed concentration 500 ppmand using the below-mentioned Present compounds as a test compoundaccording to the test example 3. As a result of the test, thebelow-mentioned Present compounds showed 90% or greater as the morality.

Present compound number: Present compounds A-1, A-2, A-3, A-6, A-11,A-12, A-18, A-23, A-26, A-31, A-33, A-34, A-39, A-83, B-3, B-17, C-1,and C-2.

Test Example 4

The test compounds are made to a formulation according to a similarmethod to that described in the Formulation Example 5, and thereto isadded water to prepare a diluted solution containing a prescribedconcentration of the test compound.

Five (5) mL of the diluted solutions described above are added to acontainer, and therein is installed Rice seedling (on the developmentalstage of the second true leaf) that is planted in a container having ahole in the bottom. After 7 days, 20 3rd instar larvae of brownplanthoppe res (Nalaparvata lugens) are released. After 6 days, thenumber of the surviving insects is examined, and the morality iscalculated by the following equation.Morality (%)={1−the number of the surviving insects/20}×100

The test was conducted by making the prescribed concentration 1,000 ppmand using the below-mentioned Present compounds as a test compoundaccording to the test Example 4. As a result of the test, thebelow-mentioned Present compounds showed 90% or greater as the morality.

Present compound number: Present compounds A-1, A-2, A-3, A-6, A-7, A-8,A-11, A-12, A-14, A-16, A-17, A-18, A-19, A-20, A-23, A-24, A-28, A-29,A-31, A-33, A-34, A-35, A-36, A-37, A-38, A-39, A-40, A-54, A-55, A-56,A-57, A-58, A-59, A-60, A-66, A-67, A-68, A-69, A-70, A-71, A-72, A-79,B-2, B-3, C-1, C-2, and C-5.

Test Example 5

The test compounds are made to a formulation according to a similarmethod to that described in the Formulation Example 5, and thereto isadded water containing 0.03 v/v % of a spreader to prepare a dilutedsolution containing a prescribed concentration of the test compound.

The diluted solutions are sprayed into the cabbage (Brassicae oleracea)seedling (on the developmental stage of the second to third true leaf)that is planted in a container in a ratio of 20 mL/seedling. Thereafter,the stem and leaf thereof is cut out and then is installed into thecontainer that is covered with the filter paper. Five cabbage moths(Plutella xylostella) at the second instar larval stages are releasedinto the cup. After 5 days, the surviving insects are counted, and themortality of insects is calculated by the following equation.Morality (%)={1−the number of the surviving insects/5}×100

The test was conducted by making the prescribed concentration 500 ppmand using the below-mentioned Present compounds as a test compoundaccording to the test example 5 As a result of the test, thebelow-mentioned Present compounds showed 80% or greater as the morality.

Present compound number: Present compounds A-1, A-2, A-3, A-6, A-7, A-8,A-9, A-10, A-11, A-12, A-13, A-14, A-15, A-16, A-17, A-18, A-19, A-21,A-22, A-23, A-24, A-25, A-26, A-27, A-30, A-31, A-33, A-34, A-35, A-36,A-37, A-38, A-39, A-41, A-53, A-63, A-75, A-80, A-81, B-3, B-8, B-9,B-11, and B-13.

Test Example 6

The test compounds are made to a formulation according to a similarmethod to that described in the Formulation Example 5, and thereto isadded water containing 0.03 v/v % of a spreader to prepare a dilutedsolution containing a prescribed concentration of the test compound.

The diluted solutions are sprayed into the cucumber seedling (on thedevelopmental stage of the third to fourth true leaf) that is planted ina container in a ratio of 20 mL/seedling. Thereafter, 10 cabbage moths(Plutella xylostella) at the third instar larval stages are releasedinto the container. After 5 days, the surviving insects are counted, andthe mortality of insects is calculated by the following equation.Morality (%)={1−the number of the surviving insects/10}×100

The test was conducted by making the prescribed concentration 200 ppmand using the below-mentioned Present compounds as a test compoundaccording to the Test Example 6. As a result of the test, thebelow-mentioned Present compounds showed 90% or greater as the morality.

Present compound number: Present compounds A-1, A-2, A-3, A-7, A-8, A-9,A-12, A-13, A-18, A-19, A-20, A-21, A-22, A-23, A-24, A-25, A-26, A-27,A-28, A-29, A-31, A-33, A-34, A-35, A-36, A-37, A-38, A-39, A-40, A-41,A-53, A-54, A-56, A-57, A-58, A-59, A-60, A-61, A-66, A-67, A-68, A-69,A-75, A-79, B-2, B-3, B-13, C-2, C-3, and C-4.

Test Example 7

The test compounds are dissolved into a mixed solution ofpolyoxyethylene sorbitan mono-cocoate and acetone (acetone andpolyoxyethylene sorbitan mono-cocoate=5:95 (v/v ratio)) in a ratio of 50μL of the mixed solution per 1 mg of the test compound. Thereto is addedwater containing 0.03% by volume of a spreader to prepare a dilutedsolution containing a prescribed concentration of the test compound.

The young seedling Corns (Zea mays) are immersed into the dilutedsolution for 30 seconds. Thereafter, two grains of the seedling areinstalled in a plastic petri dish (90 mm radiue), and 10 western cornrootworms (Diabrotica virgifera virgifera) at the second instar larvalstages are released onto the container. After 5 days, the number of thedied insects are counted and the mortality of insects is calculated bythe following equation,Morality (%)=(the number of the died insects/10)×100

The test was conducted by making the prescribed concentration 500 ppmand using the below-mentioned Present compounds as a test compoundaccording to the Test Example 7. As a result of the test, thebelow-mentioned Present compounds showed 80% or greater as the morality.

Present compound number: Present compounds A-1, A-3, A-5, A-7, A-8,A-11, A-13, A-18, A-19, A-20, A-22, A-23, A-26 A-31, A-33, A-34, A-38,A-39, A-40, A-66, and B-3

Test Example 8

The test compounds are made to a formulation according to a similarmethod to that described in the Formulation Example 5, and thereto isadded water containing 0.03 v/v % of a spreader to prepare a dilutedsolution containing a prescribed concentration of the test compound.

Silverleaf whiteflies (Bemisia tabaci) are released on tomato(Lycopersicon esculentum) seedling that is planted in the container, andthen spawn for about 24 hours. The seedling are stored for 8 days, andthe larvae of cilverleaf whiteflies are hatched from the laid eggs. Thediluted solutions are sprayed into the seedling in a ratio of 10mL/seedling. After 7 days, the number of the surviving insects isexamined, and the controlling value is calculated by the followingequation.Controlling value (%)={1−(Cb×Tai)/(Cai×Tb)}×100wherein the symbols in the formula represent the following descriptions.

Cb: Number of the insects shortly before the treatment in untreatedgroup;

Cai: Number of the surviving insects at the time of the investigation inuntreated group;

Tb: Number of the insects shortly before the treatment in treated group;

Tai: Number of the surviving insects at the time of the investigation intreated group;

Here the “untreated group” represents a group where the similartreatment procedure to that of the treated group except not using thetest compound is done.

The test was conducted by making the prescribed concentration 200 ppmand using the below-mentioned Present compounds as a test compoundaccording to the test example 8. As a result of the test, thebelow-mentioned Present compounds showed 90% or greater as the morality.

Present compound number: Present compounds A-1, A-2, A-7, A-11, A-12,A-18, A-20, A-23, A-26, A-31, A-33, A-34, A-39, A-54, A-55, A-56, A-59,A-61, A-66, A-67, A-69, and A-79.

Test Example 9

The test compounds are made to a formulation according to a similarmethod to that described in the Formulation Example 5, and thereto isadded water containing 0.03 v/v % of a spreader to prepare a dilutedsolution containing a prescribed concentration of the test compound.

The diluted solutions are sprayed into the cabbage (Brassicae oleracea)seedling (on the developmental stage of the second to third true leaf)that is planted in a container in a ratio of 20 mLf seedling.Thereafter, the stem and leaf thereof is cut out and then is ins ailedinto the container that is covered with the filter paper. Five orientalleaf worm moths (Spodoptera litura) at the second instar larval stagesare released into the cup. After 5 days, the surviving insects arecounted, and the mortality of insects is calculated by the followingequation.Morality (%)={1−the number of the surviving insects/5}×100

The test was conducted by making the prescribed concentration 500 ppmand using the below-mentioned Present compounds as test compoundaccording to the test example 9. As a result of the test, thebelow-mentioned Present compounds showed 80% or greater as the morality.

Present compound number: Present compounds A-12, A-13, A-18, A-23, A-26,A-31, A-33, A-34, A-35, A-36, A-37, A-38, A-39, A-81_(v) B-9, B-11, andB-13.

Test Example 10

The present compounds are dissolved into a mixed solution of xylene, DMFand surfactants (xylene, DMF and surfactants=4:4:1 (v/v ratio)) in aratio of 10 μL of the mixed solution per 1 mg of the present compound.The mixture is diluted with water containing 0.03% by volume of aspreader to prepare a diluted solution A containing a prescribedconcentration the present compound.

The present ingredients are dissolved into a mixed solution of xylene,DMF and surfactants (xylene, DMF and surfactants=4:4:1 (v/v ratio)) in aratio of 10 μL of the mixed solution per 1 mg of the present compound.The mixture is diluted with water containing 0.03% by volume of aspreader to prepare a diluted solution B containing a prescribedconcentration of the present ingredient.

The diluted solution A is mixed with the diluted solution B to preparediluted solution C.

Leaf discs of Cucumber (Cucumber sativus) cotyledon (length 1.5 cm) areplaced in each well of 24-well microplate. Two (2) apterous adults and 8larvae of cotton aphids (Aphis gossypii) per one well are released andthe diluted solution C is sprayed at 20 μL per one well. The group isdefined as “treated group”. A well that is sprayed with 20 μL of watercontaining 0.02% by volume of a spreader instead of the diluted solutionC is defined as “untreated group”.

After drying the diluted solution C, the upper microplate is coveredwith a film sheet. After 5 days, the number of the surviving insects ineach well is examined.

The controlling value is calculated by the following equation.Controlling value (%)={1−(Tai)/(Cai)}×100wherein the symbols in the equation represent the followingdescriptions.

Cai: Number of the surviving insects at the time of the examination inuntreated group;

Tai: Number of the surviving insects at the time of the examination intreated group.

Specific examples of the diluted solution C whose efficacies can beconfirmed by Test Example 11 include the followings) to 5).

1) A diluted solution C comprising any combinations described in theList. A wherein the concentration of the present compound is 200 ppm,and the concentration of the present ingredient is 2,000 ppm. Here inthe List A, “Comp X” represents a compound selected from any one of thepresent compounds A-1 to, A-98, B-1 to B28, and C-1 to C-10,List A:Comp X+Clot hianidin; Comp X+Thiamethoxam; Comp X+Imidacloprid; CompX+Thiacloprid; Comp X+Furupirajituron; Comp X+Sulfoxaflor; CompX+Triflumezopyrim; Comp X+Dicloromezotiaz; Comp X+Beta-cyfluthrin; CompX+Tefluthrin; Comp X+Fipronil; Comp X+Chlorantraniliprole; CompX+Cyantraniliprole; Comp X+Tetraniliprole; Comp X+Thiodicarb; CompX+Carbofuran; Comp X+Fluxametamide; Comp X+Afoxolaner; CompX+Fluralaner; Comp X+Broflanilide; Comp X+Avermectin; Comp X+Fluopyram;Comp X+Fluensulfone; Comp X+Fluazaindolizine; Comp X+Tioxazafen; CompX+Flupyrimin; Comp X+Mycorrhizal fungi; Comp X+Bradyrhizobium japonicumTA-11; Comp X+Bacillus firmus; Comp X+Bacillus firmus 1-1582; CompX+Bacillus amyloliquefaciens; Comp X+Bacillus amyloliquefaciens FZE42;COMP X+Pasteuria nishizawae; Comp X+Pasteuria nishizwae Pn1; CompX+Pasteuria penetrans; Comp X+Tebuconazole; Comp X+Prothioconazole; CompX+Metconazole; Comp X+Ipconazole; Comp X+Triticonazole; CompX+Difenoconazole; Comp X+Imazalil; Comp X+Triadimenol; CompX+Tetraconazole; Comp X+Flutriafol; Comp X+Mandestrobin; CompX+Azoxystrobin; Comp X+Pyraclostrobin; Comp X+Trifloxystrobin; CompX+Fluoxastrobin; Comp X+Picoxystrobin; Comp X+Fenamidone; Comp X+CompX+Metalaxyl-M; Comp X+Fludioxonil; Comp X+Sedaxa e; Comp X+Penflufen;Comp X+Fluxapyroxad; Comp X+Benzovindiflupyr; Comp X+Boscalid; CompX+Carboxin; Comp X+Penthiopyrad; Comp X+Flutolanil; Comp X+Captan; CompX+thiram; Comp X+Tolclofos-methyl; Comp X+Thiabendazole; CompX+Ethaboxam; Comp X+Mancozeb; Comp X+Picarbutrazox; CompX+Oxathiapiprolin; Comp X+Silthiofam; Comp X+Inpyrfluxam.2) A diluted solution C comprising any combinations described in theList A wherein the concentration of the present compound is 200 ppm, andthe concentration of the present ingredient is 200 ppm.3) A diluted solution C comprising any combinations described in theList A wherein the concentration of the present compound is 500 ppm, andthe concentration of the present ingredient is 50 ppm.4) A diluted solution C comprising any combinations described in theList A wherein the concentration of the present compound is 500 pm, andtheconcentration of the present ingredient is 5 ppm.5) A diluted solution C comprising any combinations described in theList A wherein the concentration of the present compound is 500 ppm, andthe concentration of the present ingredient is 0.5 ppm.

INDUSTRIAL APPLICABILITY

The present compound Z shows an excellent control effect against aharmful arthropod.

The invention claimed is:
 1. A compound represented by formula (I):

wherein, R² represents a C1-C6 alkyl group, n is 0, 1 or 2, R³represents a C1-C6 chain hydrocarbon group optionally having one or moresubstituents selected from Group B, a C3-C7 cycloalkyl group optionallyhaving one or more substituents selected from group E, OR¹², NR¹¹R¹²,NR¹¹C(O)R¹³, NR¹¹C(O)OR¹⁴, a cyano group, or a halogen atom, q is 0 or1, Het represents a group represented by the following formula Het 1:

A¹ represents a nitrogen atom, A² represents CR^(4a), A³ represents anitrogen atom or CR^(4b), Q¹ represents an oxygen atom, Q² represents anoxygen atom, R⁵ represents a C1-C6 chain hydrocarbon group optionallyhaving one or more substituents selected from group F, or a C3-C6cycloalkyl group R^(4a) and R^(4b) represents a hydrogen atom, Trepresents a C1-C10 chain hydrocarbon group, wherein the C1-C10 chainhydrocarbon group has one or more halogen atoms, or OR¹ R¹ represents aC1-C10 chain hydrocarbon group, wherein the C1-C10 chain hydrocarbongroup has one or more substituents selected from the group consisting ofa cyano group and a halogen atom, a (C3-C7 cycloalkyl)C1-C3 alkyl group,or a C3-C7 cycloalkyl group, wherein the (C3-C7 cycloalkyl)C1-C3 alkylgroup and the C3-C7 cycloalkyl group each independently have one or moresubstituents selected from the group consisting of a cyano group, ahalogen atom and a C1-C6 haloalkyl group, R¹¹ represents a C1-C6 chainhydrocarbon group optionally having one or more halogen atoms, or ahydrogen atom, R¹² represents a C1-C6 chain hydrocarbon group optionallyhaving one or more substituents selected from Group F, a phenyl group, asix membered heterocyclic group, wherein the phenyl group, and the sixmembered heterocyclic group each independently may optionally have oneor more substituents selected from Group D, or a hydrogen atom, R¹³represents a hydrogen atom, a C1-C6 chain hydrocarbon group optionallyhaving one or more halogen atoms or a C3-C7 cycloalkyl group optionallyhaving one or more halogen atoms, R¹⁴ represents a C1-C6 chainhydrocarbon group optionally having one or more halogen atoms, or aC3-C7 cycloalkyl group optionally having one or more halogen atoms,Group B: a group consisting of a C1-C6 alkoxy group optionally havingone or more halogen atoms, a C3-C6 cycloalkyl group optionally havingone or more halogen atoms, a cyano group, a hydroxy group, and a halogenatom, Group D: a group consisting of a cyano group and a halogen atom,Group E: a group consisting of a C1-C6 chain hydrocarbon groupoptionally having one or more halogen atoms, a halogen atom, and a cyanogroup; Group F: a group consisting of a C3-C6 cycloalkyl groupoptionally having one or more halogen atoms, a phenyl group or a sixmembered aromatic heterocyclic group, wherein the phenyl group and thesix membered aromatic heterocyclic group each independently mayoptionally have one or more substituents selected from Group D, ahalogen atom, and a cyano group.
 2. The compound according to claim 1wherein R¹ represents a C1-C10 chain hydrocarbon group having one ormore halogen atoms, a (C3-C7 cycloalkyl)C1-C3 alkyl group having one ormore substituents selected from the group consisting of a cyano group, ahalogen atom and a C1-C6 haloalkyl group, or a C3-C7 cycloalkyl grouphaving one or more substituents selected from Group G the groupconsisting of a cyano group, a halogen atom and a C1-C6 haloalkyl group.3. The compound according to claim 1, wherein A³ represents CR^(4b). 4.The compound according to claim 1, wherein T represents a C1-05 chainhydrocarbon group having one or more halogen atoms, or OR¹.
 5. Thecompound according to claim 1, wherein T represents a C1-05 chainhydrocarbon group having one or more halogen atoms, or OR¹, and R¹represents a C1-05 chain hydrocarbon group having one or more halogenatoms.
 6. The compound according to claim 1, wherein R³ represents aC1-C6 alkyl group optionally having one or more substituents selectedfrom Group B, a C3-C7 cycloalkyl group optionally having one or moresubstituents selected from Group E, NR¹¹R¹², NR¹¹C(O)OR¹⁴, OR¹², or ahalogen atom.
 7. The compound according to claim 1 wherein R² representsan ethyl group.
 8. A composition for controlling harmful arthropodcomprising the compound according to claim 1 and an inert carrier.
 9. Amethod for controlling harmful arthropod which comprises applying aneffective amount of the compound according to claim 1 to a harmfularthropod or a habitat where a harmful arthropod lives.
 10. A method forcontrolling harmful arthropod which comprises applying an effectiveamount of the compound according to claim 1 to a plant or a soil where aplant grows.
 11. A method for controlling harmful arthropod whichcomprises applying an effective amount of the compound according toclaim 1 to a seed or a bulb.
 12. A composition comprising the compoundaccording to claim 1 and one or more ingredients selected from: Group(a): insecticidal ingredients, miticidal ingredients, and nematicidalingredients; Group (b): fungicidal ingredients; Group (c): plant growthmodulating ingredients; Group (d): phytotoxicity-reducing ingredients;and Group (e): synergist ingredients.
 13. A composition for controllingpest comprising the composition according to claim 12 and an inertcarrier.
 14. A method for controlling pest which comprises applying aneffective amount of the composition according to claim 12 to a pest or ahabitat where a pest lives.
 15. A method for controlling pest whichcomprises applying an effective amount of the composition according toclaim 12 to a plant or a soil where a plant grows.
 16. A method forcontrolling pest which comprises applying an effective amount of thecompound according to claim 12 to a seed or a bulb.
 17. A seed or bulbcarrying an effective amount of the compound according to claim
 1. 18. Acompound represented by formula (II):

wherein, R² represents a C1-C6 alkyl group, n is 0, 1 or 2, A²represents CR^(4a), a combination of A³ and A⁴ represents a combinationwhere A³ represents a nitrogen atom, A⁴ represents a nitrogen atom, or acombination where A³ represents CR^(4b), and A⁴ represents a nitrogenatom, R^(4a) and R^(4b) represent a hydrogen atom, R^(w) represents aC1-C6 chain hydrocarbon group optionally having one or more halogenatoms, a benzyl group optionally having one or more substituentsselected from Group A, a C2-C7 alkylcarbonyl group, a (C1-C3alkoxy)methyl group, or a hydrogen atom, T^(w) represents a C1-C10 chainhydrocarbon group, wherein the C1-C10 chain hydrocarbon group has one ormore halogen atoms, OR¹, a halogen atom, a C1-C6 alkylsulfanyl group, aC1-C6 alkylsulfinyl group, a C1-C6 alkylsulfonyl group, wherein theC1-C6 alkylsulfanyl group, the C1-C6 alkylsulfinyl group, and the C1-C6alkylsulfonyl group each may optionally have a C3-C6 cycloalkyl group, aC3-C6 cycloalkylsulfanyl group, a C3-C6 cycloalkylsulfinyl group, aC3-C6 cycloalkylsulfonyl group, a benzyloxy group optionally having oneor more substituents selected from Group A, a C2-C7 alkylcarbonyloxygroup optionally having one or more halogen atoms, a (C1-C3alkoxy)methoxy group, or a hydroxy group, r¹ represents a C1-C10 chainhydrocarbon group, wherein the C1-C10 chain hydrocarbon group has one ormore substituents selected from the group consisting of a cyano groupand a halogen atom, a (C3-C7 cycloalkyl)C1-C3 alkyl group, or a C3-C7cycloalkyl group, wherein the (C3-C7 cycloalkyl)C1-C3 alkyl group andthe C3-C7 cycloalkyl group each independently have one or moresubstituents selected from the group consisting of a cyano group, ahalogen atom and a C1-C6 haloalkyl group, Group A: a group consisting ofa C1-C6 alkyl group optionally having one or more halogen atoms, a C1-C6alkoxy group optionally having one or more halogen atoms, a halogenatom, a cyano group and a nitro group.
 19. A compound represented byformula (III):

wherein, R² represents a C1-C6 alkyl group, n is 0, 1 or 2, A¹represents a nitrogen atom, A² represents CR⁴a, a combination of A³ andA⁴ represents a combination where A³ represents a nitrogen atom, A⁴represents a nitrogen atom or CR^(4c), or a combination where A³represents CR^(4b), and A⁴ represents a nitrogen atom, R^(4a), R^(4b)and R^(4c) represents a hydrogen atom, R^(w) represents a C1-C6 chainhydrocarbon group optionally having one or more halogen atoms, a benzylgroup optionally having one or more substituents selected from Group A,a C2-C7 alkylcarbonyl group, a (C1-C3 alkoxy)methyl group, or a hydrogenatom, T^(W2) represents a C1-C10 chain hydrocarbon group, wherein thethe C1-C10 chain hydrocarbon group has one or more halogen atoms, OR¹, ahalogen atom, a C1-C6 alkoxy group, a C1-C6 alkylsulfanyl group, a C1-C6alkylsulfinyl group, a C1-C6 alkylsulfonyl group, wherein the C1-C6alkylsulfanyl group, the C1-C6 alkylsulfinyl group, and the C1-C6alkylsulfonyl group each independently may optionally have a C3-C6cycloalkyl group, a C3-C6 cycloalkylsulfanyl group, a C3-C6cycloalkylsulfinyl group, a C3-C6 cycloalkylsulfonyl group, a benzyloxygroup optionally having one or more substituents selected from Group A,a C2-C7 alkylcarbonyloxy group optionally having one or more halogenatoms, a (C1-C3 alkoxy)methoxy group, or a hydroxy group, R¹ representsa C1-C10 chain hydrocarbon group, wherein the C1-C10 chain hydrocarbongroup has one or more substituents selected from the group consisting ofa cyano group and a halogen atom, a (C3-C7 cycloalkyl)C1-C3 alkyl group,or a C3-C7 cycloalkyl group, wherein the (C3-C7 cycloalkyl)C1-C3 alkylgroup and the C3-C7 cycloalkyl group each independently have one or moresubstituents selected from the group consisting of a cyano group, ahalogen atom and a C1-C6 haloalkyl group, R³ represents a C1-C6 chainhydrocarbon group optionally having one or more substituents selectedfrom Group B, a C3-C7 cycloalkyl group optionally having one or moresubstituents selected from group E, OR¹², NR¹¹R¹², NR¹¹C(O)R¹³,NR¹¹C(O)OR¹⁴, a cyano group, or a halogen atom, q is 0 or 1, R¹¹represents a C1-C6 chain hydrocarbon group optionally having one or morehalogen atoms, or a hydrogen atom, R¹² represents a C1-C6 chainhydrocarbon group optionally having one or more substituents selectedfrom Group F, a phenyl group, a six membered heterocyclic group, whereinthe phenyl group and the six membered heterocyclic group eachindependently may optionally have one or more substituents selected fromGroup D or a hydrogen atom R¹³ represents a hydrogen atom, a C1-C6 chainhydrocarbon group optionally having one or more halogen atoms or a C3-C7cycloalkyl group optionally having one or more halogen atoms, R¹⁴represents a C1-C6 chain hydrocarbon group optionally having one or morehalogen atoms or a C3-C7 cycloalkyl group optionally having one or morehalogen atoms, Group A: a group consisting of a C1-C6 alkyl groupoptionally having one or more halogen atoms, a C1-C6 alkoxy groupoptionally having one or more halogen atoms, a halogen atom, a cyanogroup and a nitro group, Group B: a group consisting of a C1-C6 alkoxygroup optionally having one or more halogen atoms, a C3-C6 cycloalkylgroup optionally having one or more halogen atoms, a cyano group, ahydroxy group, and a halogen atom, Group D: a group consisting of acyano group and a halogen atom, Group E: a group consisting of a C1-C6chain hydrocarbon group optionally having one or more halogen atoms, ahalogen atom, and a cyano group; Group F: a group consisting of a C3-C6cycloalkyl group optionally having one or more halogen atoms, a phenylgroup or a six membered aromatic heterocyclic group, wherein the phenylgroup and the six membered aromatic heterocyclic group eachindependently may optionally have one or more substituents selected fromGroup D, a halogen atom, and a cyano group.
 20. A compound representedby formula (IV):

wherein, R² represents a C1-C6 alkyl group, n is 0, 1 or 2, R³represents a C1-C6 chain hydrocarbon group optionally having one or moresubstituents selected from Group B, a C3-C7 cycloalkyl group optionallyhaving one or more substituents selected from group E, OR¹², NR¹¹R¹²,NR¹¹C(O)OR¹⁴, a cyano group, or a halogen atom, q is 0 or 1, Het^(W)represents a group represented by the following formula Het 3:

A¹ represents a nitrogen atom, A² represents CR^(4a), A³ represents anitrogen atom or CR^(4b), Q¹ represents an oxygen atom, R⁵ represents aC1-C6 chain hydrocarbon group optionally having one or more substituentsselected from group F, or a C3-C6 cycloalkyl group R^(4a) and R^(4b)represent a hydrogen atom, X^(L) represents a halogen atom, a C1-C6alkoxy group, a C1-C6 alkylsulfanyl group, a C1-C6 alkylsulfinyl group,a C1-C6 alkylsulfonyl group, wherein the C1-C6 alkylsulfanyl group, theC1-C6 alkylsulfinyl group, and the C1-C6 alkylsulfonyl group eachindependently may optionally have a C3-C6 cycloalkyl group, a C3-C6cycloalkylsulfanyl group, a C3-C6 cycloalkylsulfinyl group, a C3-C6cycloalkylsulfonyl group, a benzyloxy group optionally having one ormore substituents selected from Group A, a C2-C7 alkylcarbonyloxy groupoptionally having one or more halogen atoms, a (C1-C3 alkoxy)methoxygroup, or a hydroxy group, R¹¹ represents a C1-C6 chain hydrocarbongroup optionally one or more halogen atoms, or a hydrogen atom, R¹²represents a C1-C6 chain hydrocarbon group optionally having one or moresubstituents selected from Group F, a phenyl group, or six memberedheterocyclic group, wherein the phenyl group, and the six memberedheterocyclic group each independently may have optionally one or moresubstituents selected from Group D or a hydrogen atom, R¹³ represents ahydrogen atom, a C1-C6 chain hydrocarbon group optionally having one ormore halogen atoms or a C3-C7 cycloalkyl group optionally having one ormore halogen atoms, R¹⁴ represents a C1-C6 chain hydrocarbon groupoptionally having one or more halogen atoms, or a C3-C7 cycloalkyl groupoptionally having one or more halogen atoms, Group A: a group consistingof a C1-C6 alkyl group optionally having one or more halogen atoms, aC1-C6 alkoxy group optionally having one or more halogen atoms, ahalogen atom, a cyano group and a nitro group, Group B: a groupconsisting of a C1-C6 alkoxy group optionally having one or more halogenatoms, a C3-C6 cycloalkyl group optionally having one or more halogenatoms, a cyano group, a hydroxy group, and a halogen atom, Group D: agroup consisting of a cyano group and a halogen atom, Group E: a groupconsisting of a C1-C6 chain hydrocarbon group optionally having one ormore halogen atoms, a halogen atom, and a cyano group; Group F: a groupconsisting of a C3-C6 cycloalkyl group optionally having one or morehalogen atoms, a phenyl group or a six membered aromatic heterocyclicgroup, wherein the phenyl group and the six membered aromaticheterocyclic group each independently may optionally have one or moresubstituents selected from Group D, a halogen atom, and a cyano group.